IL59004A0 - Substituted benzamides their preparation and pharmaceutical compositions containing them - Google Patents

Substituted benzamides their preparation and pharmaceutical compositions containing them

Info

Publication number
IL59004A0
IL59004A0 IL59004A IL5900479A IL59004A0 IL 59004 A0 IL59004 A0 IL 59004A0 IL 59004 A IL59004 A IL 59004A IL 5900479 A IL5900479 A IL 5900479A IL 59004 A0 IL59004 A0 IL 59004A0
Authority
IL
Israel
Prior art keywords
preparation
pharmaceutical compositions
compositions containing
substituted benzamides
benzamides
Prior art date
Application number
IL59004A
Other languages
English (en)
Original Assignee
Beecham Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beecham Group Ltd filed Critical Beecham Group Ltd
Publication of IL59004A0 publication Critical patent/IL59004A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/14—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing 9-azabicyclo [3.3.1] nonane ring systems, e.g. granatane, 2-aza-adamantane; Cyclic acetals thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/08—Bridged systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
IL59004A 1978-12-30 1979-12-19 Substituted benzamides their preparation and pharmaceutical compositions containing them IL59004A0 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB7850380 1978-12-30
GB7909262 1979-03-15
GB7927831 1979-08-09

Publications (1)

Publication Number Publication Date
IL59004A0 true IL59004A0 (en) 1980-03-31

Family

ID=27260652

Family Applications (1)

Application Number Title Priority Date Filing Date
IL59004A IL59004A0 (en) 1978-12-30 1979-12-19 Substituted benzamides their preparation and pharmaceutical compositions containing them

Country Status (14)

Country Link
US (5) US4273778A (de)
EP (3) EP0220339B1 (de)
AR (1) AR225301A1 (de)
AT (1) ATE24320T1 (de)
AU (2) AU527837B2 (de)
CA (2) CA1218062A (de)
DE (3) DE2967642D1 (de)
DK (1) DK553979A (de)
ES (1) ES8101072A1 (de)
IE (2) IE49737B1 (de)
IL (1) IL59004A0 (de)
MX (1) MX6255E (de)
NZ (1) NZ192476A (de)
ZA (1) ZA797054B (de)

Families Citing this family (99)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL59004A0 (en) 1978-12-30 1980-03-31 Beecham Group Ltd Substituted benzamides their preparation and pharmaceutical compositions containing them
FR2476088A2 (fr) * 1979-01-16 1981-08-21 Delalande Sa Nouveaux derives du nor-tropane, leur procede de preparation et leur application en therapeutique
US4424358A (en) 1979-01-16 1984-01-03 Delalande S.A. β-3-Amino nor-tropane compounds
US4350691A (en) * 1979-12-20 1982-09-21 Beecham Group Limited Certain azabicyclocarboxamides and compositions containing same
US4416683A (en) * 1980-09-16 1983-11-22 Eli Lilly And Company Benzamides, compositions and agricultural method
US4943634A (en) * 1980-09-16 1990-07-24 Eli Lilly And Company N-heterocyclic benzamides
US5086184A (en) * 1980-09-16 1992-02-04 Dowelanco N-heterocyclic benzamides
FR2493848B2 (fr) * 1980-11-07 1986-05-16 Delalande Sa Nouveaux derives des nor-tropane et granatane, leur procede de preparation et leur application en therapeutique
ZA818221B (en) * 1980-12-12 1982-10-27 Beecham Group Plc Pharmaceutical compounds
US4430435A (en) 1980-12-24 1984-02-07 Burroughs Wellcome Co. Assay system
EP0057536A1 (de) * 1981-01-26 1982-08-11 Beecham Group Plc Pharmazeutisch aktive Verbindungen
US4353922A (en) * 1981-03-13 1982-10-12 Syntex (U.S.A.) Inc. Anticholinergic bronchodilators
EP0067565A1 (de) * 1981-06-16 1982-12-22 Beecham Group Plc Bicyclische Benzamide, Verfahren zu ihrer Herstellung und ihre Verwendung
EP0069481A1 (de) * 1981-06-17 1983-01-12 Beecham Group Plc Azabicycloalkylbenzamide, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zusammensetzungen
DE3268378D1 (en) * 1981-06-17 1986-02-20 Beecham Group Plc Alkylthio derivatives of azabicyclobenzamides, their preparation and pharmaceutical compositions
EP0068699A1 (de) * 1981-06-22 1983-01-05 Beecham Group Plc Decahydrochinolylbenzamide, Verfahren zu ihrer Herstellung, und diese enthaltende pharmazeutische Zusammensetzungen
EP0068700A1 (de) * 1981-06-29 1983-01-05 Beecham Group Plc Azabicycloalkylbenzamide, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zusammensetzungen
EP0069482A1 (de) * 1981-06-29 1983-01-12 Beecham Group Plc Azabicycloalkylbenzamide, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zusammensetzungen
GB2111479A (en) * 1981-10-01 1983-07-06 Beecham Group Plc Benzamides
EP0083737A1 (de) * 1981-12-15 1983-07-20 Beecham Group Plc N-Azabicycloalkan-Benzamide, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zusammenstellungen
EP0093488A3 (de) * 1982-03-18 1984-05-23 Beecham Group Plc Nortropyl-Benzopyrrolinon-Verbindungen, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zusammensetzungen
US4612319A (en) * 1982-04-14 1986-09-16 Beecham Group P.L.C. Bridged quinolizidinylbenzamides, compositions containing them and methods for their use
NZ203861A (en) * 1982-04-14 1986-07-11 Beecham Group Plc Bicyclic heterocyclic compounds and pharmaceutical compositions containing such
DE3368061D1 (en) * 1982-05-11 1987-01-15 Beecham Group Plc Azabicycloalkane derivatives, their preparation and medicaments containing them
AU1508183A (en) * 1982-06-04 1983-12-08 Beecham Group Plc Benzamide and anilide derivatives of 8-azabicyclo-(3.2.1)- -octane
FI74707C (fi) * 1982-06-29 1988-03-10 Sandoz Ag Foerfarande foer framstaellning av terapeutiskt anvaendbara alkylenoeverbryggade piperidylestrar eller -amider av bicykliska karboxylsyror.
EP0099194A3 (de) * 1982-07-03 1984-04-11 Beecham Group Plc Benzamide
JPS5936675A (ja) * 1982-07-13 1984-02-28 サンド・アクチエンゲゼルシヤフト 二環性複素環式カルボン酸アザビシクロアルキルエステルまたはアミド
EP0101641A3 (de) * 1982-07-22 1984-03-28 Beecham Group Plc Sulphonylamino-aza-bicycloalkyl-Derivate
EP0102195A3 (de) * 1982-08-03 1984-04-11 Beecham Group Plc Substituierte Azabicycloalkyl-Derivate mit dopaminantagonistischer Wirkung
EP0126087A1 (de) * 1982-09-24 1984-11-28 Beecham Group Plc Amino-azabicycloalkyl-derivate als dopamin-antagonisten
GB8302483D0 (en) * 1983-01-29 1983-03-02 Beecham Group Plc Compounds
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GB8317597D0 (en) * 1983-06-29 1983-08-03 Beecham Group Plc Pharmaceutical compounds
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FR2557110B1 (fr) * 1983-12-23 1989-11-24 Sandoz Sa Nouveaux derives d'amines cycliques, leur preparation et leur utilisation comme medicaments
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GB8516371D0 (en) * 1985-06-28 1985-07-31 Beecham Group Plc Compounds
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DE3629598A1 (de) * 1986-08-30 1988-03-03 Boehringer Ingelheim Kg 3-brom-2,6-dimethoxibenzamide, ihre herstellung und verwendung
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US5240146A (en) * 1990-12-14 1993-08-31 Smedley William H Variable proportion dispenser
IL100432A (en) * 1990-12-27 1996-01-19 Erba Carlo Spa Dihydrobenzofuran carboxamide derivatives their preparation and pharmaceutical compositions containing them
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FR2831884B1 (fr) 2001-11-02 2003-12-26 Pf Medicament Nouveaux derives amides heteroaromatiques de 3 beta-amino azabicyclooctane, leur procede de preparation et leurs applications en therapeutique
HUP0202001A2 (hu) * 2002-06-14 2005-08-29 Sanofi-Aventis DDP-IV gátló hatású azabiciklooktán- és nonánszármazékok
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AU2004215679A1 (en) 2003-02-27 2004-09-10 F. Hoffmann-La Roche Ag CCR-3 receptor antagonists
DE602004010299T2 (de) 2003-12-22 2008-09-18 Memory Pharmaceuticals Corp. Indole, 1h-indazole, 1,2-benzisoxazole und 1,2-benzisothiazole und deren herstellung und anwendungen
NZ550534A (en) 2004-03-25 2009-07-31 Memory Pharm Corp Indazoles, benzothiazoles, benzoisothiazoles, benzisoxazoles, and preparation and uses thereof
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JP2007538011A (ja) 2004-05-07 2007-12-27 メモリー・ファーマシューティカルズ・コーポレイション １ｈ−インダゾール、ベンゾチアゾール、１，２−ベンゾイソキサゾール、１，２−ベンゾイソチアゾール、およびクロモン、ならびにそれらの調製および使用
RU2418797C2 (ru) 2004-12-22 2011-05-20 Мемори Фармасьютиклз Корпорейшн Лиганды никотинового рецептора альфа-7, их получение и применение
US8106066B2 (en) 2005-09-23 2012-01-31 Memory Pharmaceuticals Corporation Indazoles, benzothiazoles, benzoisothiazoles, benzisoxazoles, pyrazolopyridines, isothiazolopyridines, and preparation and uses thereof
SI2336125T1 (sl) * 2008-04-11 2013-04-30 Janssen Pharmaceutica N.V. Tiazolopiridin-2-iloksi-fenil in tiazolopirazin-2-iloksi-fenil amini kot modulatorji levkotrien a4 hidrolaze
CN102459251B (zh) * 2009-05-14 2015-05-20 詹森药业有限公司 作为白三烯a4水解酶的调节剂的具有两个稠合双环杂芳基部分的化合物
CN104860946A (zh) * 2015-05-14 2015-08-26 湖北生物医药产业技术研究院有限公司 Ccr5拮抗剂的制备方法
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CN116751196B (zh) * 2023-05-08 2025-08-29 大连万福制药有限公司 一种高效合成马拉维诺中间体n-苄基托品胺的方法

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IL59004A0 (en) 1978-12-30 1980-03-31 Beecham Group Ltd Substituted benzamides their preparation and pharmaceutical compositions containing them
FR2446823A1 (fr) * 1979-01-16 1980-08-14 Delalande Sa Nouveaux derives du nor-tropane, leur procede de preparation et leur application en therapeutique
US4424358A (en) * 1979-01-16 1984-01-03 Delalande S.A. β-3-Amino nor-tropane compounds

Also Published As

Publication number Publication date
CA1220473A (en) 1987-04-14
DE2966476D1 (en) 1984-01-12
MX6255E (es) 1985-02-15
CA1218062A (en) 1987-02-17
IE49737B1 (en) 1985-12-11
IE792524L (en) 1980-06-30
IE49736B1 (en) 1985-12-11
US4336259A (en) 1982-06-22
US4705858A (en) 1987-11-10
AU9135182A (en) 1983-03-10
AU543825B2 (en) 1985-05-02
EP0081054B1 (de) 1986-12-17
EP0220339A1 (de) 1987-05-06
AU527837B2 (en) 1983-03-24
EP0013138A1 (de) 1980-07-09
EP0081054A2 (de) 1983-06-15
EP0220339B1 (de) 1989-11-08
EP0013138B1 (de) 1983-12-07
ATE24320T1 (de) 1987-01-15
NZ192476A (en) 1982-09-14
AR225301A1 (es) 1982-03-15
AU5425579A (en) 1980-07-03
US4599420A (en) 1986-07-08
DK553979A (da) 1980-08-15
ES487379A0 (es) 1980-12-01
ES8101072A1 (es) 1980-12-01
US4544660A (en) 1985-10-01
ZA797054B (en) 1980-12-31
DE2967692D1 (de) 1989-12-14
US4273778A (en) 1981-06-16
EP0081054A3 (en) 1983-08-24
DE2967642D1 (de) 1987-01-29

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