IL59992A0 - Morphinan-6-one derivatives and their use as medicines - Google Patents

Morphinan-6-one derivatives and their use as medicines

Info

Publication number: IL59992A0
Authority: IL; Israel
Prior art keywords: methyl; morphinan; medicines; derivatives; cyclobutylmethyl
Prior art date: 1979-05-21

Application number

IL59992A

Other languages

English (en)

Original Assignee

Miles Lab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1979-05-21

Filing date

1980-05-05

Publication date

1980-07-31

1979-05-21 Priority claimed from US06/040,664 external-priority patent/US4230712A/en

1980-05-05 Application filed by Miles Lab filed Critical Miles Lab

1980-07-31 Publication of IL59992A0 publication Critical patent/IL59992A0/xx

Links

XUSCOHKHRDQKCI-ARFHVFGLSA-N (1S,9R,10R)-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2,4,6-trien-13-one Chemical class C1C(=O)CC[C@H]2[C@]3([H])NCC[C@@]21C1=CC=CC=C1C3 XUSCOHKHRDQKCI-ARFHVFGLSA-N 0.000 title abstract 2
229940079593 drug Drugs 0.000 title 1
239000003814 drug Substances 0.000 title 1
125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 2
125000000217 alkyl group Chemical group 0.000 abstract 1
229940035676 analgesics Drugs 0.000 abstract 1
239000000730 antalgic agent Substances 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
125000004850 cyclobutylmethyl group Chemical group C1(CCC1)C* 0.000 abstract 1
125000004186 cyclopropylmethyl group Chemical group [H]C([H])(*)C1([H])C([H])([H])C1([H])[H] 0.000 abstract 1
125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 1
239000003887 narcotic antagonist Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/22—Bridged ring systems
- C07D221/28—Morphinans
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Pain & Pain Management (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Biomedical Technology (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Other In-Based Heterocyclic Compounds (AREA)

IL59992A 1979-05-21 1980-05-05 Morphinan-6-one derivatives and their use as medicines IL59992A0 (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US06/040,664 US4230712A (en)	1978-02-10	1979-05-21	7-Methyl-8β-lower alkyl or 7-methyl-8-lower alkyl B/C cis or trans morphinan-6-one compounds and therapeutic method of treating pain employing them

Publications (1)

Publication Number	Publication Date
IL59992A0 true IL59992A0 (en)	1980-07-31

Family

ID=21912259

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL59992A IL59992A0 (en)	1979-05-21	1980-05-05	Morphinan-6-one derivatives and their use as medicines

Country Status (6)

Country	Link
EP (1)	EP0019254B1 (de)
JP (1)	JPS55154957A (de)
AT (1)	ATE1502T1 (de)
CA (1)	CA1135692A (de)
DE (1)	DE3060798D1 (de)
IL (1)	IL59992A0 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4370333A (en) *	1981-06-29	1983-01-25	Sisa, Incorporated	17-Cyclopropylmethyl-3-hydroxy-14-methoxy 7α-methyl-morphinan-6-one and therapeutic method of treating pain with it
ES2653265T3 (es) *	2012-12-28	2018-02-06	Purdue Pharma Lp	Morfinanos sustituidos y el uso de éstos

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2178010A (en) *	1937-02-03	1939-10-31	Small Lyndon Frederick	Nuclear substituted derivatives of the morphine series and methods for their preparation
US3654280A (en) *	1968-03-21	1972-04-04	Shionogi & Co	L-n allylic-3-hydroxy-6-oxomorphinans
CA1093070A (en) *	1978-02-10	1981-01-06	Michael P. Kotick	8.beta.-ALKYL-SUBSTITUTED MORPHINAN-6-ONE COMPOUNDS

1980
- 1980-04-30 CA CA000350957A patent/CA1135692A/en not_active Expired
- 1980-05-05 IL IL59992A patent/IL59992A0/xx unknown
- 1980-05-12 AT AT80102616T patent/ATE1502T1/de not_active IP Right Cessation
- 1980-05-12 DE DE8080102616T patent/DE3060798D1/de not_active Expired
- 1980-05-12 EP EP80102616A patent/EP0019254B1/de not_active Expired
- 1980-05-20 JP JP6603880A patent/JPS55154957A/ja active Pending

Also Published As

Publication number	Publication date
ATE1502T1 (de)	1982-09-15
JPS55154957A (en)	1980-12-02
CA1135692A (en)	1982-11-16
EP0019254A1 (de)	1980-11-26
DE3060798D1 (en)	1982-10-28
EP0019254B1 (de)	1982-09-01

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