IL61930A - 25-hydroxy-26,26,26,27,27,27-hexafluorocholecalciferol and pharmaceutical compositions containing it - Google Patents

25-hydroxy-26,26,26,27,27,27-hexafluorocholecalciferol and pharmaceutical compositions containing it

Info

Publication number: IL61930A
Authority: IL; Israel
Prior art keywords: hexafluorocholecalciferol; hydroxy; pharmaceutical compositions; compositions containing; pharmaceutical
Prior art date: 1980-02-04

Application number

IL61930A

Other languages

English (en)

Other versions

IL61930A0 (en

Original Assignee

Wisconsin Alumni Res Found

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1980-02-04

Filing date

1981-01-19

Publication date

1984-11-30

1981-01-19 Application filed by Wisconsin Alumni Res Found filed Critical Wisconsin Alumni Res Found

1981-01-19 Priority to IL7050581A priority Critical patent/IL70505A/xx

1981-02-27 Publication of IL61930A0 publication Critical patent/IL61930A0/xx

1983-12-21 Priority to IL70505A priority patent/IL70505A0/xx

1984-11-30 Publication of IL61930A publication Critical patent/IL61930A/xx

Links

UYSBDEYGNDFSLX-BKMDTPKSSA-N (1r,3z)-3-[(2e)-2-[(1r,3as,7ar)-7a-methyl-1-[(2r)-7,7,7-trifluoro-6-hydroxy-6-(trifluoromethyl)heptan-2-yl]-2,3,3a,5,6,7-hexahydro-1h-inden-4-ylidene]ethylidene]-4-methylidenecyclohexan-1-ol Chemical compound C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@@H](CCCC(O)(C(F)(F)F)C(F)(F)F)C)=C\C=C1\C[C@H](O)CCC1=C UYSBDEYGNDFSLX-BKMDTPKSSA-N 0.000 title 1
239000008194 pharmaceutical composition Substances 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J17/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Steroid Compounds (AREA)

IL61930A 1980-02-04 1981-01-19 25-hydroxy-26,26,26,27,27,27-hexafluorocholecalciferol and pharmaceutical compositions containing it IL61930A (en)

Priority Applications (2)

Application Number	Priority Date	Filing Date	Title
IL7050581A IL70505A (en)	1980-02-04	1981-01-19	3beta,25-dihydroxy-26,26,26,27,27,27-hexafluoro-cholest-5-ene and-cholesta-5,7-diene and 3beta-ester and ether derivatives thereof
IL70505A IL70505A0 (en)	1980-02-04	1983-12-21	3beta,25-dihydroxy-26,26,26,27,27,27-hexafluoro-cholest-5-ene and cholesta-5,7-diene and 3beta-ester and ether derivatives thereof

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US06/118,149 US4248791A (en)	1980-02-04	1980-02-04	25-Hydroxy-26,26,26,27,27,27-hexafluorocholecalciferol

Publications (2)

Publication Number	Publication Date
IL61930A0 IL61930A0 (en)	1981-02-27
IL61930A true IL61930A (en)	1984-11-30

Family

ID=22376765

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL61930A IL61930A (en)	1980-02-04	1981-01-19	25-hydroxy-26,26,26,27,27,27-hexafluorocholecalciferol and pharmaceutical compositions containing it

Country Status (12)

Country	Link
US (1)	US4248791A (de)
AU (1)	AU544294B2 (de)
BE (1)	BE887344A (de)
CH (2)	CH651295A5 (de)
DK (1)	DK436981A (de)
FR (1)	FR2477145B1 (de)
GB (2)	GB2082586B (de)
IE (1)	IE50815B1 (de)
IL (1)	IL61930A (de)
IT (1)	IT1194789B (de)
NZ (1)	NZ196039A (de)
WO (1)	WO1981002298A1 (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4248791A (en) *	1980-02-04	1981-02-03	Wisconsin Alumni Research Foundation	25-Hydroxy-26,26,26,27,27,27-hexafluorocholecalciferol
US4358406A (en) *	1981-07-27	1982-11-09	Wisconsin Alumni Research Foundation	26,26,26,27,27,27-Hexafluoro-1α,25-dihydroxycholecalciferol and process for preparing same
US4411833A (en) *	1982-05-26	1983-10-25	Wisconsin Alumni Research Foundation	Method for preparing 26,26,26,27,27,27-hexafluoro-1α,25-dihydroxycholesterol
JPS59500864A (ja) *	1982-05-26	1984-05-17	ウイスコンシン　アラムナイ　リサ−チ　フオンデ−シヨン	２６，２６．２６，２７．２７，２７―ヘキサフルオロ―１α，２５―ジヒドロキシコレステロール化合物及びその製造方法
US4613594A (en) *	1984-11-16	1986-09-23	Hoffmann-La Roche Inc.	Fluorinated vitamin D3 compounds
ZA859138B (en) *	1984-12-19	1986-08-27	Hoffmann La Roche	Cholecalciferol derivatives
EP0205025A1 (de) *	1985-05-27	1986-12-17	Sumitomo Pharmaceuticals Company, Limited	Fluorin enthaltende Vitamin-D3-Derivate und Zelldifferenzierung induzierende Mittel, die sie als aktiven Wirkstoff enthalten
JPH0764804B2 (ja) *	1986-04-25	1995-07-12	住友製薬株式会社	活性型ビタミンｄ３のフッ素誘導体
CA1314872C (en)	1986-04-25	1993-03-23	Toshio Nishizawa	Fluorine derivatives of vitamin d _and process for producing the same
US4853378A (en) *	1986-10-20	1989-08-01	Sumitomo Chemical Company, Limited	Fluorine derivatives of vitamin D3 and process for producing the same
JPS63196556A (ja) *	1987-02-10	1988-08-15	Taisho Pharmaceut Co Ltd	含フツ素ビタミンｄ誘導体
JPH0737476B2 (ja) *	1991-01-17	1995-04-26	ウイスコンシンアラムナイリサーチフオンデーシヨン	２６，２６，２６，２７，２７，２７−ヘキサフルオロ−１α，２５−ジヒドロキシコレステロール
BR9405735A (pt) *	1993-02-19	1995-12-05	Wisconsin Alumni Res Found	Uso de 26,26,26,27,27,27-hexaflúor-1-alfa 25-dihidróxi colecalciferol para o tratamento de distúrbios do metabolismo do cálcio
US5428029A (en) *	1993-11-24	1995-06-27	Hoffmann-La Roche Inc.	Vitamin D3 fluorinated analogs
CA2981549A1 (en) *	2009-01-27	2010-08-05	Berg Llc	Vitamin d3 and analogs thereof for alleviating side effects associated with chemotherapy
CN106265695B (zh)	2009-08-14	2021-05-07	博格有限责任公司	用于治疗脱发的维生素d3及其类似物
CA2776464C (en) *	2009-10-02	2017-10-24	Wisconsin Alumni Research Foundation	1-desoxy-2-methylene-19-nor-vitamin d analogs and their uses
CN112156097A (zh)	2013-05-29	2021-01-01	博格有限责任公司	使用维生素d预防或减轻化疗诱发的脱发
US20200281944A1 (en) *	2017-11-17	2020-09-10	Mahmood Piraee	Combinations Of Lanosterol Or 25-Hydroxycholesterol Including Derivatives Thereof Useful In The Treatment Of Lens Disorders

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4069321A (en) *	1975-10-14	1978-01-17	Merck & Co., Inc.	Blocked cholecalciferol and dihydrotachysterol 3 derivatives
US4196133A (en) *	1979-03-05	1980-04-01	Wisconsin Alumni Research Foundation	24,24-Difluoro-25-hydroxycholecalciferol
US4248791A (en) *	1980-02-04	1981-02-03	Wisconsin Alumni Research Foundation	25-Hydroxy-26,26,26,27,27,27-hexafluorocholecalciferol

1980
- 1980-02-04 US US06/118,149 patent/US4248791A/en not_active Expired - Lifetime
1981
- 1981-01-13 CH CH6517/81A patent/CH651295A5/de not_active IP Right Cessation
- 1981-01-13 CH CH1134/85A patent/CH652725A5/de not_active IP Right Cessation
- 1981-01-13 WO PCT/US1981/000035 patent/WO1981002298A1/en not_active Ceased
- 1981-01-16 NZ NZ196039A patent/NZ196039A/xx unknown
- 1981-01-19 IL IL61930A patent/IL61930A/xx unknown
- 1981-02-02 IE IE196/81A patent/IE50815B1/en unknown
- 1981-02-02 GB GB8132235A patent/GB2082586B/en not_active Expired
- 1981-02-02 BE BE0/203676A patent/BE887344A/fr unknown
- 1981-02-02 IT IT19459/81A patent/IT1194789B/it active
- 1981-02-02 FR FR8101957A patent/FR2477145B1/fr not_active Expired
- 1981-02-02 GB GB8103086A patent/GB2068382B/en not_active Expired
- 1981-02-03 AU AU66846/81A patent/AU544294B2/en not_active Ceased
- 1981-10-02 DK DK436981A patent/DK436981A/da unknown

Also Published As

Publication number	Publication date
GB2082586B (en)	1983-10-05
NZ196039A (en)	1983-07-15
AU6684681A (en)	1981-08-13
FR2477145A1 (fr)	1981-09-04
IE810196L (en)	1981-08-04
IL61930A0 (en)	1981-02-27
IE50815B1 (en)	1986-07-23
AU544294B2 (en)	1985-05-23
CH652725A5 (de)	1985-11-29
US4248791A (en)	1981-02-03
BE887344A (fr)	1981-06-01
IT8119459A0 (it)	1981-02-02
FR2477145B1 (fr)	1985-09-20
WO1981002298A1 (en)	1981-08-20
DK436981A (da)	1981-10-02
IT1194789B (it)	1988-09-28
GB2068382B (en)	1984-02-29
GB2068382A (en)	1981-08-12
GB2082586A (en)	1982-03-10
CH651295A5 (de)	1985-09-13

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