IL66547A - T-even bacteriophage dna fragment as a stabilizer for proteins expressed by cloned dna and its production - Google Patents
T-even bacteriophage dna fragment as a stabilizer for proteins expressed by cloned dna and its productionInfo
- Publication number
- IL66547A IL66547A IL66547A IL6654782A IL66547A IL 66547 A IL66547 A IL 66547A IL 66547 A IL66547 A IL 66547A IL 6654782 A IL6654782 A IL 6654782A IL 66547 A IL66547 A IL 66547A
- Authority
- IL
- Israel
- Prior art keywords
- dna
- dna fragment
- isolated
- fragments
- proteins expressed
- Prior art date
Links
- 239000012634 fragment Substances 0.000 title abstract 8
- 108090000623 proteins and genes Proteins 0.000 title abstract 5
- 102000004169 proteins and genes Human genes 0.000 title abstract 5
- 241001515965 unidentified phage Species 0.000 title abstract 3
- 239000003381 stabilizer Substances 0.000 title 1
- 230000001580 bacterial effect Effects 0.000 abstract 4
- 238000010367 cloning Methods 0.000 abstract 3
- 230000002159 abnormal effect Effects 0.000 abstract 2
- 230000015556 catabolic process Effects 0.000 abstract 2
- 238000006731 degradation reaction Methods 0.000 abstract 2
- 230000007246 mechanism Effects 0.000 abstract 1
- 239000002773 nucleotide Substances 0.000 abstract 1
- 125000003729 nucleotide group Chemical group 0.000 abstract 1
- 239000013612 plasmid Substances 0.000 abstract 1
- 230000017854 proteolysis Effects 0.000 abstract 1
- 108091008146 restriction endonucleases Proteins 0.000 abstract 1
- 230000000087 stabilizing effect Effects 0.000 abstract 1
- 230000001131 transforming effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/555—Interferons [IFN]
- C07K14/565—IFN-beta
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/67—General methods for enhancing the expression
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/70—Vectors or expression systems specially adapted for E. coli
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2795/00—Bacteriophages
- C12N2795/00011—Details
- C12N2795/10011—Details dsDNA Bacteriophages
- C12N2795/10111—Myoviridae
- C12N2795/10122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Landscapes
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Wood Science & Technology (AREA)
- Molecular Biology (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Gastroenterology & Hepatology (AREA)
- Physics & Mathematics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Plant Pathology (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Virology (AREA)
- Toxicology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Enzymes And Modification Thereof (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US29361481A | 1981-08-17 | 1981-08-17 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL66547A0 IL66547A0 (en) | 1982-12-31 |
| IL66547A true IL66547A (en) | 1989-02-28 |
Family
ID=23129795
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL66547A IL66547A (en) | 1981-08-17 | 1982-08-15 | T-even bacteriophage dna fragment as a stabilizer for proteins expressed by cloned dna and its production |
Country Status (7)
| Country | Link |
|---|---|
| EP (1) | EP0072925B1 (de) |
| AT (1) | ATE34584T1 (de) |
| AU (1) | AU551490B2 (de) |
| CA (1) | CA1207253A (de) |
| DE (1) | DE3278539D1 (de) |
| DK (1) | DK315582A (de) |
| IL (1) | IL66547A (de) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4673641A (en) * | 1982-12-16 | 1987-06-16 | Molecular Genetics Research And Development Limited Partnership | Co-aggregate purification of proteins |
| EP0133044B1 (de) * | 1983-08-01 | 1990-11-07 | The Research Foundation Of State University Of New York | Stabilisierung von Fremdproteinen und Plasmide zur Verwendung hierfür |
| US4758512A (en) * | 1984-03-06 | 1988-07-19 | President And Fellows Of Harvard College | Hosts and methods for producing recombinant products in high yields |
| US5028531A (en) * | 1984-03-19 | 1991-07-02 | Fujisawa Pharmaceutical Company, Ltd. | IGF-I fusion proteins; protection of IGF-I from degradation by host cell; and processes for the production thereof |
| DK108685A (da) * | 1984-03-19 | 1985-09-20 | Fujisawa Pharmaceutical Co | Vaekstfaktor i |
| US4663281A (en) * | 1984-03-22 | 1987-05-05 | Mass Institute Of Technology | Enhanced production of proteinaceous materials in eucaryotic cells |
| EP0212285A1 (de) * | 1985-07-29 | 1987-03-04 | Arthur A. Gottlieb | Herleitung und Verwendung ausgewählter Genprodukte |
| AU582288B2 (en) * | 1986-03-07 | 1989-03-16 | Damon Biotech Inc. | Vector and method for achieving high level expression in eukaryotic cells |
| CA1340740C (en) * | 1987-12-08 | 1999-09-14 | Eileen R. Mulvihill | Co-expression in eukaryotic cells |
| US5648254A (en) * | 1988-01-15 | 1997-07-15 | Zymogenetics, Inc. | Co-expression in eukaryotic cells |
| US6982153B1 (en) | 1998-12-03 | 2006-01-03 | Targanta Therapeutics, Inc. | DNA sequences from staphylococcus aureus bacteriophage 77 that encode anti-microbial polypeptides |
| JP2002531107A (ja) * | 1998-12-03 | 2002-09-24 | フェージテック，インコーポレーテッド | バクテリオファージゲノミクスに基づく新規抗微生物剤の開発 |
| JP2004515251A (ja) | 2000-12-19 | 2004-05-27 | ファゲテック，インコーポレイティド | スタフィロコッカス・アウレウス必須遺伝子及びそのコードされるタンパク質ｓｔａａｕ＿ｒ９に関連する組成物及び方法 |
-
1982
- 1982-06-25 CA CA000405949A patent/CA1207253A/en not_active Expired
- 1982-07-14 DK DK315582A patent/DK315582A/da not_active Application Discontinuation
- 1982-07-20 AU AU86206/82A patent/AU551490B2/en not_active Ceased
- 1982-07-21 DE DE8282106599T patent/DE3278539D1/de not_active Expired
- 1982-07-21 AT AT82106599T patent/ATE34584T1/de active
- 1982-07-21 EP EP82106599A patent/EP0072925B1/de not_active Expired
- 1982-08-15 IL IL66547A patent/IL66547A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP0072925A3 (en) | 1984-02-01 |
| DK315582A (da) | 1983-02-18 |
| ATE34584T1 (de) | 1988-06-15 |
| EP0072925B1 (de) | 1988-05-25 |
| AU8620682A (en) | 1983-02-24 |
| DE3278539D1 (en) | 1988-06-30 |
| EP0072925A2 (de) | 1983-03-02 |
| AU551490B2 (en) | 1986-05-01 |
| CA1207253A (en) | 1986-07-08 |
| IL66547A0 (en) | 1982-12-31 |
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