IL69056A - Method of treating non-human mammals with cyclic ketenedithioacetal derivatives,pharmaceutical compositions containing them,certain new such compounds and their preparation - Google Patents

Method of treating non-human mammals with cyclic ketenedithioacetal derivatives,pharmaceutical compositions containing them,certain new such compounds and their preparation

Info

Publication number
IL69056A
IL69056A IL69056A IL6905683A IL69056A IL 69056 A IL69056 A IL 69056A IL 69056 A IL69056 A IL 69056A IL 6905683 A IL6905683 A IL 6905683A IL 69056 A IL69056 A IL 69056A
Authority
IL
Israel
Prior art keywords
sub
compounds
cyclic
preparation
pharmaceutical compositions
Prior art date
Application number
IL69056A
Other languages
English (en)
Other versions
IL69056A0 (en
Original Assignee
Zyma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zyma Sa filed Critical Zyma Sa
Publication of IL69056A0 publication Critical patent/IL69056A0/xx
Publication of IL69056A publication Critical patent/IL69056A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/10—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
    • C07D295/104—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/108—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/385—Heterocyclic compounds having sulfur as a ring hetero atom having two or more sulfur atoms in the same ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
    • C07C45/46—Friedel-Crafts reactions
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/84—Ketones containing a keto group bound to a six-membered aromatic ring containing ether groups, groups, groups, or groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D339/00—Heterocyclic compounds containing rings having two sulfur atoms as the only ring hetero atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D339/00—Heterocyclic compounds containing rings having two sulfur atoms as the only ring hetero atoms
    • C07D339/02—Five-membered rings
    • C07D339/06—Five-membered rings having the hetero atoms in positions 1 and 3, e.g. cyclic dithiocarbonates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D339/00—Heterocyclic compounds containing rings having two sulfur atoms as the only ring hetero atoms
    • C07D339/08—Six-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Cephalosporin Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pyrane Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
IL69056A 1982-06-25 1983-06-23 Method of treating non-human mammals with cyclic ketenedithioacetal derivatives,pharmaceutical compositions containing them,certain new such compounds and their preparation IL69056A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8218472 1982-06-25

Publications (2)

Publication Number Publication Date
IL69056A0 IL69056A0 (en) 1983-10-31
IL69056A true IL69056A (en) 1987-12-31

Family

ID=10531279

Family Applications (1)

Application Number Title Priority Date Filing Date
IL69056A IL69056A (en) 1982-06-25 1983-06-23 Method of treating non-human mammals with cyclic ketenedithioacetal derivatives,pharmaceutical compositions containing them,certain new such compounds and their preparation

Country Status (21)

Country Link
US (2) US4818765A (da)
EP (1) EP0099329B1 (da)
JP (1) JPS5916887A (da)
KR (1) KR900007319B1 (da)
AT (1) ATE57927T1 (da)
AU (1) AU566303B2 (da)
CA (1) CA1239402A (da)
DD (1) DD210908A5 (da)
DE (1) DE3381964D1 (da)
DK (1) DK292883A (da)
FI (1) FI832291L (da)
GB (1) GB2124211B (da)
GR (1) GR79552B (da)
HU (1) HU194862B (da)
IE (1) IE55484B1 (da)
IL (1) IL69056A (da)
NO (1) NO832314L (da)
NZ (1) NZ204700A (da)
PH (1) PH25133A (da)
PT (1) PT76934B (da)
ZA (1) ZA834636B (da)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3586541T2 (de) * 1985-05-31 1993-01-14 Banyu Pharma Co Ltd 1,3-dithiol-2-ylidenderivate.
DE3587252T2 (de) * 1985-10-09 1993-07-15 Nihon Nohyaku Co Ltd Keten-s,s,-acetalderivate, verfahren zu ihrer herstellung und methode zur heilung von mykose unter verwendung dieser derivate.
JPS62158215A (ja) * 1985-12-28 1987-07-14 Nippon Nohyaku Co Ltd 脂肪壊死症治療剤
GB2188842A (en) * 1986-02-05 1987-10-14 Zyma Sa Cyclic dithiols for treating pulmonary fibrosis
EP0234480A3 (en) * 1986-02-21 1988-09-14 Nihon Nohyaku Co., Ltd. 1, 3-diketone derivatives and their use
CA1327361C (en) * 1988-01-14 1994-03-01 Nihon Nohyaku Co., Ltd. Ketenedithioacetal derivative and processes for producing the same as well as a composition containing the same
KR920009818A (ko) * 1990-11-26 1992-06-25 쯔무라 아끼라 신규 벤조디옥솔 유도체 및 이를 함유하는 간장해 개선제
DE19645313A1 (de) 1996-11-04 1998-05-07 Basf Ag Substituierte 3-Benzylpyrazole
US7498331B2 (en) * 2003-11-06 2009-03-03 United States Of America As Represented By The Secretary Of The Army Arthropod repellent pharmacophore models, compounds identified as fitting the pharmacophore models, and methods of making and using thereof
DE102013110740A1 (de) * 2013-09-27 2015-04-02 Karlsruher Institut für Technologie Polymer-fixierte Dithiolan- bzw. Dithianderivate
CA2957785C (en) 2014-08-11 2023-01-03 Angion Biomedica Corporation Cytochrome p450 inhibitors and uses thereof
CA2970819A1 (en) 2014-12-31 2016-07-07 Angion Biomedica Corp. Methods and agents for treating disease

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3525751A (en) * 1967-03-27 1970-08-25 Syntex Corp Hormonal diphenyl methylol and benzhydrylidene derivatives
FR1582882A (da) * 1968-06-25 1969-10-10
US3781281A (en) * 1972-11-08 1973-12-25 Du Pont 2-arylidene-1,3-dithioles and preparation thereof from acethylenes,carbon disulfide,and aromatic aldehydes in the presence of aliphatic phosphines
GB1604739A (en) * 1977-07-28 1981-12-16 Yamanouchi Pharma Co Ltd 7-methoxy-7-(1,3-dithietane-2-carboxamide) cephalosporanic acid derivatives
GB1604738A (en) * 1977-07-28 1981-12-16 Yamanouchi Pharma Co Ltd 1,3-dithietane-2-carboxylic acid derivatives and the preparation thereof

Also Published As

Publication number Publication date
PT76934A (en) 1983-07-01
GR79552B (da) 1984-10-30
IL69056A0 (en) 1983-10-31
NZ204700A (en) 1986-03-14
ZA834636B (en) 1984-03-28
HU194862B (en) 1988-03-28
DE3381964D1 (de) 1990-12-06
PT76934B (en) 1986-04-21
GB8316086D0 (en) 1983-07-20
JPS5916887A (ja) 1984-01-28
KR900007319B1 (ko) 1990-10-08
US4946861A (en) 1990-08-07
AU566303B2 (en) 1987-10-15
PH25133A (en) 1991-02-19
IE55484B1 (en) 1990-09-26
ATE57927T1 (de) 1990-11-15
GB2124211A (en) 1984-02-15
EP0099329A1 (en) 1984-01-25
NO832314L (no) 1983-12-27
FI832291A0 (fi) 1983-06-22
AU1626183A (en) 1984-01-05
EP0099329B1 (en) 1990-10-31
DD210908A5 (de) 1984-06-27
DK292883A (da) 1983-12-26
DK292883D0 (da) 1983-06-24
US4818765A (en) 1989-04-04
CA1239402A (en) 1988-07-19
FI832291A7 (fi) 1983-12-26
FI832291L (fi) 1983-12-26
KR840005126A (ko) 1984-11-03
IE831479L (en) 1983-12-25
GB2124211B (en) 1985-12-24

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