IL72018A - Biologically active heptapeptides structurally related to region within growth hormones and pharmaceutical compositions comprising them - Google Patents

Biologically active heptapeptides structurally related to region within growth hormones and pharmaceutical compositions comprising them

Info

Publication number
IL72018A
IL72018A IL72018A IL7201884A IL72018A IL 72018 A IL72018 A IL 72018A IL 72018 A IL72018 A IL 72018A IL 7201884 A IL7201884 A IL 7201884A IL 72018 A IL72018 A IL 72018A
Authority
IL
Israel
Prior art keywords
sub
hgh
analogs
amino acid
acid residues
Prior art date
Application number
IL72018A
Other languages
English (en)
Other versions
IL72018A0 (en
Original Assignee
Amgen
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amgen filed Critical Amgen
Publication of IL72018A0 publication Critical patent/IL72018A0/xx
Publication of IL72018A publication Critical patent/IL72018A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/61—Growth hormone [GH], i.e. somatotropin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1002—Tetrapeptides with the first amino acid being neutral
    • C07K5/1016—Tetrapeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/12—Growth hormone, growth factor other than t-cell or b-cell growth factor, and growth hormone releasing factor; related peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Endocrinology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Diabetes (AREA)
  • Animal Behavior & Ethology (AREA)
  • Zoology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Toxicology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Emergency Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
IL72018A 1983-06-04 1984-06-04 Biologically active heptapeptides structurally related to region within growth hormones and pharmaceutical compositions comprising them IL72018A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/501,024 US4699897A (en) 1983-06-04 1983-06-04 Biologically active peptides structurally related to regions within growth hormones

Publications (2)

Publication Number Publication Date
IL72018A0 IL72018A0 (en) 1984-10-31
IL72018A true IL72018A (en) 1990-03-19

Family

ID=23991846

Family Applications (1)

Application Number Title Priority Date Filing Date
IL72018A IL72018A (en) 1983-06-04 1984-06-04 Biologically active heptapeptides structurally related to region within growth hormones and pharmaceutical compositions comprising them

Country Status (8)

Country Link
US (1) US4699897A (de)
EP (1) EP0137904B1 (de)
JP (1) JPH07116229B2 (de)
AT (1) ATE50266T1 (de)
CA (1) CA1267995A (de)
DE (1) DE3481306D1 (de)
IL (1) IL72018A (de)
WO (1) WO1984004915A1 (de)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0238473A3 (de) * 1986-03-18 1989-06-07 Monsanto Company Serinprotease-Hemmungsstoffe
US5244882A (en) * 1987-03-12 1993-09-14 Amgen, Inc. Porcine growth hormone analogs, and compositions
US5104806A (en) * 1987-03-12 1992-04-14 Amgen, Inc. Porcine growth hormone analogs encoding dna
GB8707398D0 (en) * 1987-03-27 1987-04-29 Coopers Animal Health Biologically active molecules
GB8718937D0 (en) * 1987-08-11 1987-09-16 Coopers Animal Health Biologically active molecules
US5864008A (en) * 1988-03-25 1999-01-26 James; Stephen Peptides derived from foot-and-mouth disease virus, pharmaceutical compositions, and methods for using the peptides
JPH03503416A (ja) * 1988-03-25 1991-08-01 マリンクロットベタリナリィ，インコーポレイテッド ペプチド
US5688666A (en) * 1988-10-28 1997-11-18 Genentech, Inc. Growth hormone variants with altered binding properties
US6780613B1 (en) * 1988-10-28 2004-08-24 Genentech, Inc. Growth hormone variants
US5534617A (en) * 1988-10-28 1996-07-09 Genentech, Inc. Human growth hormone variants having greater affinity for human growth hormone receptor at site 1
CA2345497A1 (en) 1988-10-28 1990-04-28 Genentech, Inc. Growth hormone variants and method for forming growth hormone variants
US5179080A (en) * 1989-08-31 1993-01-12 Clinical Homecare, Corp. Formulations containing growth hormone and nutritional supplements, and methods of treating malnutrition in chronic lung disease
DE69129154T2 (de) * 1990-12-03 1998-08-20 Genentech, Inc., South San Francisco, Calif. Verfahren zur anreicherung von proteinvarianten mit geänderten bindungseigenschaften
JPH07508025A (ja) * 1992-05-08 1995-09-07 トーマス・ジェファーソン・ユニバーシティ インスリン様増殖因子（ｉｇｆ−１）類似体
SE9203496D0 (sv) * 1992-11-20 1992-11-20 Kabi Pharmacia Ab New oligopeptides
US5928896A (en) * 1993-04-23 1999-07-27 Virginia Commonwealth University Polypeptides that include conformation-constraining groups which flank a protein--protein interaction site
WO1994025482A1 (en) * 1993-04-23 1994-11-10 Evans Herbert J Polypeptides that include conformation-constraining groups which flank a protein-protein interaction site
US6258550B1 (en) 1993-04-23 2001-07-10 Virginia Commonwealth University Polypeptides that include conformation-constraining groups which flank a protein-protein interaction site
US5952465A (en) * 1993-04-23 1999-09-14 Virginia Commonwealth University Polypeptides that include conformation-constraining groups which flank a protein-protein interaction site
US5965698A (en) * 1993-04-23 1999-10-12 Virginia Commonwealth University Polypeptides that include conformation-constraining groups which flank a protein--protein interaction site
US6084066A (en) * 1993-10-29 2000-07-04 Virginia Commonwealth University Polypetides that include conformation-constraining groups which flank a protein-protein interaction site
US6184208B1 (en) 1994-06-29 2001-02-06 Immunotech Developments Inc. Peptide, a method for its preparation and a pharmaceutical composition containing the peptide
RU2107691C1 (ru) * 1995-03-02 1998-03-27 Дейгин Владислав Исакович Пептид и способ его получения
JP3628333B2 (ja) * 1995-09-21 2005-03-09 ジェネンテック インコーポレーテッド ヒト成長ホルモン変異体
US6159940A (en) * 1996-02-28 2000-12-12 Immunotech Developments Inc. Method for modulating hemopoiesis
EP1663377A4 (de) 2003-08-07 2011-09-07 Merit Medical Systems Inc Therapeutisches medizinisches gerät, abgabe und anwendungsverfahren

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2843525A (en) * 1953-01-23 1958-07-15 Allen & Hanburys Ltd Insulin synthetic poly-amino acid complexes
US3326763A (en) * 1962-01-08 1967-06-20 Protein Foundation Inc Reagent for increasing activity of insulin
US3698912A (en) * 1969-07-01 1972-10-17 Morton Norwich Products Inc Process for making nutrient composition
US3868358A (en) * 1971-04-30 1975-02-25 Lilly Co Eli Protamine-insulin product
US3912807A (en) * 1974-04-18 1975-10-14 American Home Prod Treatment of diabetes using somatostatin and insulin
FR2296427A1 (fr) * 1974-12-31 1976-07-30 Choay Sa Agent peptidique de regulation de la glycemie
US3941763A (en) * 1975-03-28 1976-03-02 American Home Products Corporation PGlu-D-Met-Trp-Ser-Tyr-D-Ala-Leu-Arg-Pro-Gly-NH2 and intermediates
DE2658984C2 (de) * 1976-12-27 1983-08-18 Thera Gesellschaft für Patentverwertung mbH, 8036 Herrsching Injizierbare Insulinpräparate
US4407948A (en) * 1977-09-23 1983-10-04 The Regents Of The University Of California Purification of nucleotide sequences suitable for expression in bacteria
EP0053029A1 (de) * 1980-11-24 1982-06-02 Peninsula Laboratories Incorporated Nicht-enkephalinartige Peptide, ihre Herstellung, sie enthaltende Zusammensetzungen und ihre medizinische und tierärztliche Verwendung
US4438032A (en) * 1981-01-30 1984-03-20 The Regents Of The University Of California Unique T-lymphocyte line and products derived therefrom
US4558033A (en) * 1983-06-06 1985-12-10 Amgen Potentiation of the effects of insulin by peptides

Also Published As

Publication number Publication date
US4699897A (en) 1987-10-13
JPS60501504A (ja) 1985-09-12
EP0137904A2 (de) 1985-04-24
JPH07116229B2 (ja) 1995-12-13
CA1267995A (en) 1990-04-17
DE3481306D1 (de) 1990-03-15
WO1984004915A1 (en) 1984-12-20
EP0137904B1 (de) 1990-02-07
EP0137904A3 (en) 1987-01-07
IL72018A0 (en) 1984-10-31
ATE50266T1 (de) 1990-02-15

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Legal Events

Date Code Title Description
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees
ERR Corrigendum

Free format text: CORRECT DATE OF PRIORITY NUMBER 29.04.2016