IL75359A - Injection apparatus with electrical blood absorbing stimulation - Google Patents

Injection apparatus with electrical blood absorbing stimulation

Info

Publication number
IL75359A
IL75359A IL75359A IL7535985A IL75359A IL 75359 A IL75359 A IL 75359A IL 75359 A IL75359 A IL 75359A IL 7535985 A IL7535985 A IL 7535985A IL 75359 A IL75359 A IL 75359A
Authority
IL
Israel
Prior art keywords
injection
blood flow
muscle tissue
patient
received
Prior art date
Application number
IL75359A
Other languages
English (en)
Other versions
IL75359A0 (en
Original Assignee
Survival Technology
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/638,695 external-priority patent/US4658830A/en
Priority claimed from US06/708,845 external-priority patent/US4661469A/en
Application filed by Survival Technology filed Critical Survival Technology
Publication of IL75359A0 publication Critical patent/IL75359A0/xx
Publication of IL75359A publication Critical patent/IL75359A/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/02—Ammonia; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/44—Oxidoreductases (1)
    • A61K38/446—Superoxide dismutase (1.15)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/49—Urokinase; Tissue plasminogen activator
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M5/2066—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically comprising means for injection of two or more media, e.g. by mixing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/327—Applying electric currents by contact electrodes alternating or intermittent currents for enhancing the absorption properties of tissue, e.g. by electroporation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/36014—External stimulators, e.g. with patch electrodes
    • A61N1/36017—External stimulators, e.g. with patch electrodes with leads or electrodes penetrating the skin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y115/00—Oxidoreductases acting on superoxide as acceptor (1.15)
    • C12Y115/01—Oxidoreductases acting on superoxide as acceptor (1.15) with NAD or NADP as acceptor (1.15.1)
    • C12Y115/01001—Superoxide dismutase (1.15.1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21068—Tissue plasminogen activator (3.4.21.68), i.e. tPA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M2005/1787—Syringes for sequential delivery of fluids, e.g. first medicament and then flushing liquid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M2005/206—With automatic needle insertion
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M2005/2073—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically preventing premature release, e.g. by making use of a safety lock
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/19—Syringes having more than one chamber, e.g. including a manifold coupling two parallelly aligned syringes through separate channels to a common discharge assembly
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/372—Arrangements in connection with the implantation of stimulators
    • A61N1/375—Constructional arrangements, e.g. casings
    • A61N1/3756—Casings with electrodes thereon, e.g. leadless stimulators

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biophysics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Wood Science & Technology (AREA)
  • Dermatology (AREA)
  • Inorganic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Vascular Medicine (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Electrotherapy Devices (AREA)
  • Catching Or Destruction (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
IL75359A 1984-08-08 1985-05-31 Injection apparatus with electrical blood absorbing stimulation IL75359A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US06/638,695 US4658830A (en) 1984-08-08 1984-08-08 Method and apparatus for initiating reperfusion treatment by an unattended individual undergoing heart attack symptoms
US06/708,845 US4661469A (en) 1984-08-08 1985-03-06 t-PA composition capable of being absorbed into the blood stream and method of administration
US06/735,311 US4832682A (en) 1984-08-08 1985-05-20 Injection method and apparatus with electrical blood absorbing stimulation

Publications (2)

Publication Number Publication Date
IL75359A0 IL75359A0 (en) 1985-09-29
IL75359A true IL75359A (en) 1990-12-23

Family

ID=27417625

Family Applications (1)

Application Number Title Priority Date Filing Date
IL75359A IL75359A (en) 1984-08-08 1985-05-31 Injection apparatus with electrical blood absorbing stimulation

Country Status (9)

Country Link
US (1) US4832682A (fr)
EP (1) EP0191771B1 (fr)
JP (1) JPH0613051B2 (fr)
AT (1) ATE109014T1 (fr)
AU (1) AU591871B2 (fr)
CA (1) CA1274140A (fr)
DE (1) DE3587892T2 (fr)
IL (1) IL75359A (fr)
WO (1) WO1986001120A1 (fr)

Families Citing this family (39)

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US5078680A (en) * 1984-08-08 1992-01-07 Survival Technology, Inc. Automatic injector for emergency treatment
US4689042A (en) * 1985-05-20 1987-08-25 Survival Technology, Inc. Automatic medicament ingredient mixing and injecting apparatus
DE3806562A1 (de) * 1988-03-01 1989-09-14 Alpha Therapeutic Gmbh Zweikammerspritze mit einer fuellung aus aktivitaetsempfindlichem humanen protein als wirkstoff
US6197806B1 (en) 1995-12-20 2001-03-06 Nippon Zoki Pharmaceutical Co., Ltd. Eliminating agent for activated oxygen and free radicals
JPH10182460A (ja) * 1996-12-27 1998-07-07 Nippon Zoki Pharmaceut Co Ltd ３−デオキシグルコソン生成阻害剤
AU754989B2 (en) 1998-11-16 2002-11-28 Nippon Zoki Pharmaceutical Co., Ltd. A therapeutic agent for intractable vasculitis
US6713291B2 (en) * 1999-01-28 2004-03-30 Alan D. King Electrodes coated with treating agent and uses thereof
WO2000044438A1 (fr) * 1999-01-28 2000-08-03 Cyto Pulse Sciences, Inc. Administration de macromolecules dans des cellules
US6517517B1 (en) * 2000-06-08 2003-02-11 Mayo Foundation For Medical Education And Research Automated injection device for administration of liquid medicament
US6423050B1 (en) * 2000-06-16 2002-07-23 Zbylut J. Twardowski Method and apparatus for locking of central-vein catheters
JP4711523B2 (ja) 2001-02-13 2011-06-29 日本臓器製薬株式会社 低アルブミン血症改善剤
WO2003024507A2 (fr) * 2001-09-19 2003-03-27 Biovalve Technologies, Inc. Microaiguilles, jeux de microaiguilles, et systemes et procedes associes
EP1480712A2 (fr) * 2001-09-28 2004-12-01 BioValve Technologies, Inc. Matrices de microaiguilles commutables, et systemes et procedes associes
US6912417B1 (en) * 2002-04-05 2005-06-28 Ichor Medical Systmes, Inc. Method and apparatus for delivery of therapeutic agents
IL157981A (en) 2003-09-17 2014-01-30 Elcam Medical Agricultural Cooperative Ass Ltd Auto injector
CA2559083C (fr) 2004-03-08 2015-06-16 Ichor Medical Systems, Inc. Appareil ameliore pour une administration electriquement mediee d'agents therapeutiques
IL160891A0 (en) 2004-03-16 2004-08-31 Auto-mix needle
US20050273054A1 (en) * 2004-06-03 2005-12-08 Florida Atlantic University Epinephrine auto-injector
WO2006084173A1 (fr) * 2005-02-04 2006-08-10 The Johns Hopkins University Systeme de canon de therapie genique par electroporation
ES2688900T3 (es) 2007-11-12 2018-11-07 Medicom Innovation Partner A/S Autoinyector con ubicaciones de anclaje cambiantes para un accionador mecánico
JP2013538643A (ja) * 2010-10-04 2013-10-17 ナーボマトリクス リミテッド 低インピーダンスの箇所を発見し、そこに電気的刺激を印加するための電極
US9692829B2 (en) 2012-12-03 2017-06-27 Mylan Inc. Medication delivery system and method
US20140155827A1 (en) 2012-12-03 2014-06-05 Mylan, Inc. Medicament information system and method
US9643770B2 (en) 2012-12-03 2017-05-09 Mylan Inc. System and method for medicament storage, dispensing, and administration
US9179260B2 (en) 2012-12-03 2015-11-03 Mylan Inc. Medicament information system and method
JP6709009B2 (ja) * 2014-10-06 2020-06-10 アクティヴァックスＡｋｔｉｖａｘ 自動注射器
US11020527B2 (en) 2015-07-10 2021-06-01 Alk-Abelló A/S Injector comprising a safety pin
KR102535764B1 (ko) 2016-03-28 2023-05-30 아이커 메디칼 시스템스 인코포레이티드 치료제를 전달하기 위한 장치
US11167085B2 (en) 2016-06-15 2021-11-09 True Concepts Medical Technologies, Llc Syringe systems and methods for multi-stage fluid delivery
JP6751779B2 (ja) * 2016-06-15 2020-09-09 ホプキンズ、マイケル 体液の捕集及びサンプリングのためのシリンジ・システム及び方法
AT519383B1 (de) * 2016-10-27 2018-09-15 Pharma Consult Gmbh Injektionsvorrichtung, insbesondere Autoinjektor, zur gleichzeitigen Abgabe von mehreren Medikamenten
US11565047B2 (en) 2017-01-09 2023-01-31 Verily Life Sciences Llc Wearable non-liquid medication injection device
CN212662367U (zh) * 2017-01-09 2021-03-09 威里利生命科学有限责任公司 可穿戴非液体药物注射装置
WO2019229010A1 (fr) 2018-05-29 2019-12-05 Idorsia Pharmaceuticals Ltd. Dispositif et procédé d'administration d'au moins une substance
AU2021280366B2 (en) 2020-05-29 2025-01-23 Windgap Medical, Inc. A dynamic mixing and delivery system for mixing a therapeutic agent in an injector or autoinjector
US10842949B1 (en) 2020-07-30 2020-11-24 Benson Eric Wengreen Auto-injectors featuring medicine delivery assurance
CA3191987A1 (fr) * 2020-09-08 2022-03-17 Gaetan Painchaud Auto-injecteur pour l'administration de medicaments
US12370372B2 (en) 2021-07-09 2025-07-29 Medtronic, Inc. Electrical contact for a medical device lead
JP7824793B2 (ja) * 2022-03-04 2026-03-05 テルモ株式会社 オートインジェクタ保持具および薬剤投与具

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US3078850A (en) * 1960-08-26 1963-02-26 Imp Electronics Inc Electrochemotherapeutic cardiac device
US3380449A (en) * 1964-11-02 1968-04-30 Stanley J. Sarnoff Cartridge with burstable seal
US3364929A (en) * 1964-12-21 1968-01-23 Burroughs Wellcome Co Method for administering muscle relaxant drug
US3565080A (en) * 1964-12-21 1971-02-23 Burroughs Wellcome Co Neuromuscular block monitoring apparatus
US3391695A (en) * 1966-06-17 1968-07-09 Stanley J. Sarnoff Cartridge with reflexed burstable diaphragm
US3424155A (en) * 1968-01-24 1969-01-28 Stanley J Sarnoff Burstable diaphragm seal
BE755224A (fr) * 1969-08-25 1971-02-24 Philips Nv Seringue d'injection
US3807411A (en) * 1971-08-16 1974-04-30 Concept External cardiac pacer with separable generating and power-probe units
US3882863A (en) * 1973-08-01 1975-05-13 Survival Technology Hypodermic injection device having cannula covered with resilient sheath
US4031893A (en) * 1976-05-14 1977-06-28 Survival Technology, Inc. Hypodermic injection device having means for varying the medicament capacity thereof
US4103690A (en) * 1977-03-21 1978-08-01 Cordis Corporation Self-suturing cardiac pacer lead
US4178928A (en) * 1977-08-10 1979-12-18 Tischlinger Edward A Self injector
US4226235A (en) * 1979-01-25 1980-10-07 Survival Technology, Inc. Plural injecting device
US4394863A (en) * 1981-10-23 1983-07-26 Survival Technology, Inc. Automatic injector with cartridge having separate sequentially injectable medicaments
US4413991A (en) * 1982-03-18 1983-11-08 Schmitz John B Dual dose ampule
US4658830A (en) * 1984-08-08 1987-04-21 Survival Technology, Inc. Method and apparatus for initiating reperfusion treatment by an unattended individual undergoing heart attack symptoms

Also Published As

Publication number Publication date
EP0191771A1 (fr) 1986-08-27
AU4438785A (en) 1986-03-07
EP0191771B1 (fr) 1994-07-27
JPH0613051B2 (ja) 1994-02-23
ATE109014T1 (de) 1994-08-15
US4832682A (en) 1989-05-23
JPS61502865A (ja) 1986-12-11
AU591871B2 (en) 1989-12-21
CA1274140A (fr) 1990-09-18
WO1986001120A1 (fr) 1986-02-27
IL75359A0 (en) 1985-09-29
DE3587892T2 (de) 1994-11-10
EP0191771A4 (fr) 1987-12-07
DE3587892D1 (de) 1994-09-01

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