IL76157A - Butyrolactam derivatives,their preparation and pharmaceutical compositions containing them - Google Patents

Butyrolactam derivatives,their preparation and pharmaceutical compositions containing them

Info

Publication number
IL76157A
IL76157A IL76157A IL7615785A IL76157A IL 76157 A IL76157 A IL 76157A IL 76157 A IL76157 A IL 76157A IL 7615785 A IL7615785 A IL 7615785A IL 76157 A IL76157 A IL 76157A
Authority
IL
Israel
Prior art keywords
butyrolactam
derivatives
preparation
pharmaceutical compositions
compositions containing
Prior art date
Application number
IL76157A
Other languages
English (en)
Other versions
IL76157A0 (en
Original Assignee
Chinese Acad Med Science
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chinese Acad Med Science, Bayer Ag filed Critical Chinese Acad Med Science
Publication of IL76157A0 publication Critical patent/IL76157A0/xx
Publication of IL76157A publication Critical patent/IL76157A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/80—[b, c]- or [b, d]-condensed
    • C07D209/94—[b, c]- or [b, d]-condensed containing carbocyclic rings other than six-membered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/08—Bridged systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Joining Of Building Structures In Genera (AREA)
  • Package Frames And Binding Bands (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IL76157A 1984-08-24 1985-08-21 Butyrolactam derivatives,their preparation and pharmaceutical compositions containing them IL76157A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19843431257 DE3431257A1 (de) 1984-08-24 1984-08-24 Neue (delta)-butyrolactame, pharmakologisch aktive zusammensetzungen derselben, verfahren zu ihrer herstellung und ihre medizinische verwendung

Publications (2)

Publication Number Publication Date
IL76157A0 IL76157A0 (en) 1985-12-31
IL76157A true IL76157A (en) 1988-08-31

Family

ID=6243847

Family Applications (1)

Application Number Title Priority Date Filing Date
IL76157A IL76157A (en) 1984-08-24 1985-08-21 Butyrolactam derivatives,their preparation and pharmaceutical compositions containing them

Country Status (16)

Country Link
US (1) US4879390A (fr)
EP (1) EP0172514B1 (fr)
JP (1) JPH0660159B2 (fr)
KR (1) KR860001787A (fr)
AT (1) ATE46504T1 (fr)
AU (1) AU571729B2 (fr)
CA (1) CA1262250A (fr)
DE (2) DE3431257A1 (fr)
DK (1) DK385285A (fr)
ES (2) ES8609241A1 (fr)
FI (1) FI853228A7 (fr)
GR (1) GR852050B (fr)
HU (1) HU195774B (fr)
IL (1) IL76157A (fr)
PT (1) PT81005B (fr)
ZA (1) ZA856414B (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU579029B2 (en) * 1985-10-18 1988-11-10 Bayer Aktiengesellschaft Process for the preparation of ` -butyrolactams
DE3616989A1 (de) * 1986-05-21 1987-11-26 Bayer Ag Enantiomerenreine 4,5-disubstituierte (gamma)-butyrolactame, verfahren zu ihrer herstellung und ihre verwendung
DE3927367A1 (de) * 1989-08-19 1991-02-21 Bayer Ag Verfahren zur herstellung von dehydrocycloclausenamid und dessen derivate in der racemischen form und als optisch aktive (+) oder (-)-enantiomere
DE3927370A1 (de) * 1989-08-19 1991-02-21 Bayer Ag Verfahren zur herstellung von clausenamid und neoclausenamid und deren derivate
JP4585073B2 (ja) * 2000-02-15 2010-11-24 丸善製薬株式会社 抗男性ホルモン剤、養毛化粧料、前立腺肥大抑制剤、外用剤及び飲食品
US6787564B2 (en) * 2002-03-26 2004-09-07 Institute Of Materia Medica, Chinese Academy Of Medical Sciences Optically active clausenamides, process of the preparation thereof, pharmaceutical composition containing the same and their medical use
EP1348696B1 (fr) * 2002-03-26 2012-02-01 Institute Of Materia Medica, Chinese Academy Of Medical Sciences Utilisation de clausenamides optiquement actifs pour la préparation de compositions pharmaceutiques, compositions pharmaceutiques les contenant
CN1295215C (zh) * 2002-12-31 2007-01-17 中国医学科学院药物研究所 黄皮酰胺的光学活性衍生物、其制法和其药物组合物与用途
WO2016015333A1 (fr) * 2014-08-01 2016-02-04 F.Hoffmann-La Roche Ag Dérivés de 2-oxa-5-azabicyclo[2.2.1]heptan-3-yl
CN118084757B (zh) * 2023-10-10 2025-09-16 广东药科大学 2个内酰胺类物质及其应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI325174A7 (fr) * 1973-11-19 1975-05-20 Sandoz Ag

Also Published As

Publication number Publication date
ATE46504T1 (de) 1989-10-15
DE3573113D1 (en) 1989-10-26
ES554061A0 (es) 1987-04-01
FI853228L (fi) 1986-02-25
GR852050B (fr) 1985-12-20
ES8609241A1 (es) 1986-07-16
FI853228A7 (fi) 1986-02-25
KR860001787A (ko) 1986-03-22
PT81005A (en) 1985-09-01
FI853228A0 (fi) 1985-08-22
JPS62181250A (ja) 1987-08-08
ES8704457A1 (es) 1987-04-01
CA1262250A (fr) 1989-10-10
AU4657185A (en) 1986-02-27
AU571729B2 (en) 1988-04-21
DK385285D0 (da) 1985-08-23
PT81005B (en) 1987-06-26
HU195774B (en) 1988-07-28
ZA856414B (en) 1986-04-30
HUT38904A (en) 1986-07-28
US4879390A (en) 1989-11-07
DE3431257A1 (de) 1986-03-06
EP0172514B1 (fr) 1989-09-20
EP0172514A1 (fr) 1986-02-26
ES546381A0 (es) 1986-07-16
DK385285A (da) 1986-02-25
IL76157A0 (en) 1985-12-31
JPH0660159B2 (ja) 1994-08-10

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