IL76387A - Peptide antibodies which exhibit specificity for single amino acid differences between proteins and their use in detecting oncogene products - Google Patents

Peptide antibodies which exhibit specificity for single amino acid differences between proteins and their use in detecting oncogene products

Info

Publication number
IL76387A
IL76387A IL76387A IL7638785A IL76387A IL 76387 A IL76387 A IL 76387A IL 76387 A IL76387 A IL 76387A IL 7638785 A IL7638785 A IL 7638785A IL 76387 A IL76387 A IL 76387A
Authority
IL
Israel
Prior art keywords
proteins
amino acid
single amino
acid differences
peptide antibodies
Prior art date
Application number
IL76387A
Other languages
English (en)
Other versions
IL76387A0 (en
Original Assignee
Cetus Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cetus Corp filed Critical Cetus Corp
Publication of IL76387A0 publication Critical patent/IL76387A0/xx
Publication of IL76387A publication Critical patent/IL76387A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/82—Translation products from oncogenes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/81—Packaged device or kit
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/961—Chemistry: molecular biology and microbiology including a step of forming, releasing, or exposing the antigen or forming the hapten-immunogenic carrier complex or the antigen per se
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/807—Apparatus included in process claim, e.g. physical support structures
    • Y10S436/808—Automated or kit
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/811—Test for named disease, body condition or organ function
    • Y10S436/813—Cancer

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Organic Chemistry (AREA)
  • Cell Biology (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Oncology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
IL76387A 1984-09-19 1985-09-13 Peptide antibodies which exhibit specificity for single amino acid differences between proteins and their use in detecting oncogene products IL76387A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US65275284A 1984-09-19 1984-09-19
US06/661,909 US4798787A (en) 1984-09-19 1984-10-17 Peptide antibodies and their use in detecting oncogene products

Publications (2)

Publication Number Publication Date
IL76387A0 IL76387A0 (en) 1986-01-31
IL76387A true IL76387A (en) 1991-08-16

Family

ID=27096357

Family Applications (1)

Application Number Title Priority Date Filing Date
IL76387A IL76387A (en) 1984-09-19 1985-09-13 Peptide antibodies which exhibit specificity for single amino acid differences between proteins and their use in detecting oncogene products

Country Status (8)

Country Link
US (1) US4798787A (fr)
EP (1) EP0175360A3 (fr)
AU (1) AU591461B2 (fr)
CA (1) CA1265649A (fr)
DE (1) DE175360T1 (fr)
DK (1) DK425885A (fr)
IL (1) IL76387A (fr)
NZ (1) NZ213535A (fr)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3346953A1 (de) * 1983-12-24 1985-08-14 Organogen Medizinisch-Molekularbiologische Forschungsgesellschaft mbH, 6900 Heidelberg Cardiodilatin, ein neues peptidhormon und verfahren zu seiner herstellung
US4762706A (en) * 1984-10-17 1988-08-09 Cetus Corporation Peptide antibodies and their use in detecting oncogene products
US5443956A (en) * 1985-01-29 1995-08-22 Oncogene Science, Inc. Detection, quantitation and classification of RAS proteins in body fluids and tissues
US4898932A (en) * 1985-01-29 1990-02-06 E. I. Du Pont De Nemours And Company Monoclonal antibodies reactive with activated and oncogenic ras p21 proteins
US5084380A (en) * 1985-01-29 1992-01-28 Applied Biotechnology Monoclonal antibodies reactive with activated and oncogenic ras p21 proteins
US6200764B1 (en) 1985-01-29 2001-03-13 Bayer Corporation Detection, quantitation and classification of ras proteins in body fluids and tissues
CA1296660C (fr) * 1985-01-29 1992-03-03 Walter P. Carney Anticorps monoclonal dirige contre un dodecapeptide relie a un oncogene p21 ras
EP0203587A3 (fr) * 1985-05-30 1989-08-09 F. Hoffmann-La Roche Ag Peptides ras oncogènes et anticorps
US6083709A (en) * 1985-08-21 2000-07-04 Osi Pharmaceuticals, Inc. Immunoassay for detection of mutant P53 polypeptide in serum
AU615876B2 (en) * 1985-08-21 1991-10-17 Oncogene Science, Inc. Immunoassay for the detection of Oncogene encoded products
US5015568A (en) * 1986-07-09 1991-05-14 The Wistar Institute Diagnostic methods for detecting lymphomas in humans
JPS6374492A (ja) * 1986-09-18 1988-04-04 Hiroshi Shiyuku モノクロ−ナル抗体
US4968603A (en) * 1986-12-31 1990-11-06 The Regents Of The University Of California Determination of status in neoplastic disease
CA1339069C (fr) * 1987-11-09 1997-07-29 Henry Lee Niman Recepteurs monoclonaux induits par des polypeptides pour ligans proteiniques
US5112737A (en) * 1988-02-22 1992-05-12 Applied Biotechnology, Inc. Monoclonal antibodies against activated ras proteins with amino acid mutations at position 13 of the protein
WO1989008710A1 (fr) * 1988-03-08 1989-09-21 E.I. Du Pont De Nemours And Company Anticorps monoclonaux reagissant avec des proteines ras p21 activees et oncogenes
DE68929511T2 (de) * 1988-04-22 2004-11-18 Bayer Corp. Nachweis, Quantifizierung und Klassifizierung von RAS-Proteinen in Körperflüssigkeiten und Geweben
AU3964489A (en) * 1988-07-08 1990-02-05 Smithkline Beckman Corporation Retroviral protease binding peptides
JPH04500122A (ja) * 1988-08-12 1992-01-09 プロジェンクス・インコーポレイテッド 蛋白リガンドに対するポリペプチド誘発モノクローナル受容体
FR2660757B1 (fr) * 1990-04-06 1994-05-27 Immunotech Sa Procede d'identification ou de dosage de proteines et applications.
EP0489149B1 (fr) * 1990-06-27 2001-10-17 Princeton University Sondes de detection de p53 mutant
US5620848A (en) * 1990-06-27 1997-04-15 Trustees Of Princeton University Methods for detecting mutant p53
US5650489A (en) * 1990-07-02 1997-07-22 The Arizona Board Of Regents Random bio-oligomer library, a method of synthesis thereof, and a method of use thereof
EP0576476B1 (fr) * 1991-02-01 2003-05-28 OSI Pharmaceuticals, Inc. Dosage immunologique pour detecter un polypeptide mutant p53 dans des fluides biologiques
US6150398A (en) * 1991-05-08 2000-11-21 The United States Of America As Represented By The Department Of Health And Human Services Methods for the treatment of cancer
IL107250A (en) * 1993-10-12 2001-08-08 Yeda Res & Dev Dna molecules involved in programmed cell death, proteins encoded thereby and methods and compositions using said dna molecules and proteins
US6160106A (en) * 1993-10-12 2000-12-12 Yeda Research & Development Co., Ltd. Tumor suppressor genes, proteins encoded thereby and use of said genes and proteins
US20020006629A1 (en) * 2000-02-29 2002-01-17 Danishefsky Samuel J. Affinity matrix bearing tumor-associated carbohydrate-or glycopeptide-based antigens and uses thereof

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4535058A (en) * 1982-10-01 1985-08-13 Massachusetts Institute Of Technology Characterization of oncogenes and assays based thereon
CA1252046A (fr) * 1982-11-04 1989-04-04 Martin J. Cline Methodes de depistage du cancer
US4699877A (en) * 1982-11-04 1987-10-13 The Regents Of The University Of California Methods and compositions for detecting human tumors
ZA84617B (en) * 1983-02-14 1984-09-26 Arup Sen Synthetic polypeptides from viryl oncogenes
NZ207394A (en) * 1983-03-08 1987-03-06 Commw Serum Lab Commission Detecting or determining sequence of amino acids
CA1219232A (fr) * 1983-08-17 1987-03-17 Richard A. Lerner Recepteurs monoclonaux induits par un polypeptide contre des ligands
US4658022A (en) * 1985-08-08 1987-04-14 Molecular Diagnostics, Inc. Binding of antibody reagents to denatured protein analytes

Also Published As

Publication number Publication date
DK425885A (da) 1986-03-20
US4798787A (en) 1989-01-17
EP0175360A3 (fr) 1988-03-30
EP0175360A2 (fr) 1986-03-26
NZ213535A (en) 1991-05-28
CA1265649A (fr) 1990-02-06
AU591461B2 (en) 1989-12-07
DK425885D0 (da) 1985-09-19
IL76387A0 (en) 1986-01-31
DE175360T1 (de) 1986-09-25
AU4756985A (en) 1986-03-27

Similar Documents

Publication Publication Date Title
IL76387A (en) Peptide antibodies which exhibit specificity for single amino acid differences between proteins and their use in detecting oncogene products
IL77748A (en) Amino acid and peptide derivatives as peptidase inhibitors
EP0243929A3 (en) Polypeptide and protein derivatives and process for their preparation
GB8628313D0 (en) Dna rna peptides/polypeptides
AU4876585A (en) Peptide anitbodies and their use in detecting oncogene products
ZA855031B (en) Assay for simultaneous detection of antigen and antibody in given serum
AU3227684A (en) Detection of antibodies in human serum
AU5805886A (en) Ras oncogene peptides and antibodies
EP0296796A3 (en) Analytical method and element for protein assay
NZ225392A (en) Peptide or protein sequencing method and reaction chambers for sequenators
IL64574A0 (en) Method of competitive protein binding assay
IL87730A0 (en) Peptides and antibodies
DE3477809D1 (en) Dna coding for a signal amino acid sequence and vectors containing the same
GB8413301D0 (en) Polypeptide and protein products
ZA894800B (en) Proteins and nucleic acids
IE883226L (en) Separation of nucleic acids from protein material using¹cation exchangers
DE3470608D1 (en) An improved apparatus for sequencing peptides and proteins
IL71941A0 (en) Peptide derivatives and use thereof for quantitatively assaying enzymes
DE3568298D1 (en) Process for hydrolysis of peptide or protein
IL73181A0 (en) Process for the preparation of carrier-bound fibrin and its use in a process for the determination of proteins
PT81408A (en) Process for the preparation of new peptides having activity in the factor of growth and sequence of the nucleic acid which classifies the peptides
GB8806571D0 (en) Supports for proteins & amino acids
ZA907279B (en) Antibodies and proteins
GB2212502B (en) Monoclonal antibody against membrane cytoskeleton proteins
NZ220485A (en) Peptides of 4-10 amino-acids and use in test kits for detecting aids antibodies

Legal Events

Date Code Title Description
HC Change of name of proprietor(s)
RH Patent void