IL76909A - Pharmaceutical compositions comprising tellurium-and selenium-containing compounds,some new telluro-and selenodioxyacycloalkyl halide compounds for the induction of in vivo and in vitro production of cytokines and their preparation - Google Patents

Pharmaceutical compositions comprising tellurium-and selenium-containing compounds,some new telluro-and selenodioxyacycloalkyl halide compounds for the induction of in vivo and in vitro production of cytokines and their preparation

Info

Publication number
IL76909A
IL76909A IL76909A IL7690985A IL76909A IL 76909 A IL76909 A IL 76909A IL 76909 A IL76909 A IL 76909A IL 7690985 A IL7690985 A IL 7690985A IL 76909 A IL76909 A IL 76909A
Authority
IL
Israel
Prior art keywords
selenodioxyacycloalkyl
telluro
tellurium
selenium
cytokines
Prior art date
Application number
IL76909A
Other languages
English (en)
Original Assignee
Univ Bar Ilan
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Bar Ilan filed Critical Univ Bar Ilan
Publication of IL76909A publication Critical patent/IL76909A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D517/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having selenium, tellurium, or halogen atoms as ring hetero atoms
    • C07D517/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having selenium, tellurium, or halogen atoms as ring hetero atoms in which the condensed system contains two hetero rings
    • C07D517/10—Spiro-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/095—Sulfur, selenium, or tellurium compounds, e.g. thiols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/04—Sulfur, selenium or tellurium; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D329/00—Heterocyclic compounds containing rings having oxygen and selenium or oxygen and tellurium atoms as the only ring hetero atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Inorganic Chemistry (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
IL76909A 1985-03-15 1985-11-01 Pharmaceutical compositions comprising tellurium-and selenium-containing compounds,some new telluro-and selenodioxyacycloalkyl halide compounds for the induction of in vivo and in vitro production of cytokines and their preparation IL76909A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US71254985A 1985-03-15 1985-03-15
US06/782,129 US4761490A (en) 1985-03-15 1985-09-30 Organic derivatives of tellurium and selenium and their use to stimulate cytokine production

Publications (1)

Publication Number Publication Date
IL76909A true IL76909A (en) 1990-07-12

Family

ID=27108846

Family Applications (1)

Application Number Title Priority Date Filing Date
IL76909A IL76909A (en) 1985-03-15 1985-11-01 Pharmaceutical compositions comprising tellurium-and selenium-containing compounds,some new telluro-and selenodioxyacycloalkyl halide compounds for the induction of in vivo and in vitro production of cytokines and their preparation

Country Status (9)

Country Link
US (1) US4761490A (da)
EP (1) EP0194393B1 (da)
JP (2) JPH0791286B2 (da)
CN (1) CN1018640B (da)
AU (2) AU595487B2 (da)
CA (1) CA1327046C (da)
DE (1) DE3578176D1 (da)
DK (2) DK168864B1 (da)
IL (1) IL76909A (da)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4962207A (en) * 1985-09-30 1990-10-09 Bar-Ilan University Organic derivatives of tellurium and selenium
NZ228144A (en) * 1988-03-14 1991-03-26 Univ Bar Ilan Complexes of te and se, and methods of stimulating cells using them
US4929739A (en) * 1988-03-24 1990-05-29 Bar-Ilan University Complexes of tellurium and selenium derivatives
AU3578189A (en) * 1988-04-27 1989-11-24 Immunomedics Inc. Improved radiotherapy
US4946437A (en) * 1988-12-02 1990-08-07 Bar-Ilan University Method for the stimulation of bone marrow cells
US5126149A (en) * 1989-01-26 1992-06-30 Bar-Ilan University Method of inducing the production of cytokines
US5262149A (en) * 1992-08-13 1993-11-16 Benjamin Sredni Method of treating or preventing alopecia
US5610179A (en) * 1994-12-15 1997-03-11 Sredni; Benjamin Method of treating babesiosis
JPH10510812A (ja) * 1994-12-15 1998-10-20 ベーカー ノートン ファーマスーティカルズ、インコーポレーテッド タクサン化合物およびテルルおよび／またはセレン化合物の併用により腫瘍の発育を減少させるための方法および組成物
US5654328A (en) * 1994-12-15 1997-08-05 Sredni; Benjamin Method and composition for reducing tumor development with a combination of platinum and tellurium or selenium compounds
RU2177322C1 (ru) * 2001-01-22 2001-12-27 Новицкий Юрий Алексеевич Селеновое фосфолипогликопротеиновое элемент-органическое вещество, обладающее иммуномодулирующим действием (его варианты)
RU2176916C1 (ru) * 2001-01-22 2001-12-20 Новицкий Юрий Алексеевич Селеновое гликопротеиновое элементорганическое вещество, обладающее иммуностимулирующим действием (его варианты)
US7045150B2 (en) * 2001-07-31 2006-05-16 Tellus Biotech Ltd. Tellurium containing nutrient formulation and process for enhancing the cumulative weight gain or feed efficacy in poultry
US6472381B1 (en) * 2001-10-12 2002-10-29 Biomas Inc. Method of treating psoriasis
IL146694A (en) * 2001-11-22 2010-12-30 Biomas Ltd Use of an aqueous solution containing a biologically active complex of tellurium dioxide for manufacturing a medicament
WO2005060341A2 (en) * 2003-12-18 2005-07-07 Biomas, Ltd Tellurium derivatives for prevention and treatment of neurodegenerative processes
NZ548988A (en) * 2004-01-22 2010-04-30 Biomas Ltd Therapeutic methods and pharmaceutical compositions for treating warts with tellurium compounds
ES2312012T3 (es) * 2004-09-17 2009-02-16 Biomas Ltd. Nuevos compuestos de telurio y su uso como inmunomodulares.
CA2580805A1 (en) * 2004-09-17 2006-03-23 Biomas Ltd. Use of tellurium compounds as adjuvants
EP1924254A4 (en) * 2005-09-15 2011-01-19 Biomas Ltd USE OF TELLURO COMPOUNDS FOR PROTECTION AGAINST ULTRAVIOLET RADIATION
WO2007032009A2 (en) * 2005-09-15 2007-03-22 Biomas Ltd. Use of tellurium compounds for treatment of basal cell carcinoma and/or actinic keratosis
US20100297256A1 (en) * 2007-11-23 2010-11-25 Benjamin Sredni Methods and compositions for inhibiting integrins using tellurium-containing compounds
WO2010146585A1 (en) 2009-06-16 2010-12-23 Biomas Ltd. Tellurium-containing compounds for treating viral infections
JP2012076976A (ja) * 2010-10-06 2012-04-19 National Institute For Materials Science 硫化物及びセレン化物粉体の合成方法
US11497767B2 (en) 2015-02-18 2022-11-15 Enlivex Therapeutics R&D Ltd Combination immune therapy and cytokine control therapy for cancer treatment
US11318163B2 (en) 2015-02-18 2022-05-03 Enlivex Therapeutics Ltd Combination immune therapy and cytokine control therapy for cancer treatment
US11304976B2 (en) 2015-02-18 2022-04-19 Enlivex Therapeutics Ltd Combination immune therapy and cytokine control therapy for cancer treatment
JP6884155B2 (ja) 2016-02-18 2021-06-09 エンリヴェックス セラピューティクス リミテッド 癌治療のための併用免疫療法及びサイトカイン制御療法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4239846A (en) * 1978-04-10 1980-12-16 Eastman Kodak Company Tellurium (IV) compounds and compositions
US4508662A (en) * 1983-03-24 1985-04-02 The United States Of America As Represented By The Secretary Of The Air Force Pentafluorotelluriumoxide fluorocarbons
US4578225A (en) * 1984-05-29 1986-03-25 The United States Of America As Represented By The Secretary Of The Air Force Multi-(OTeF5)-substituted fluorocarbons
US4675088A (en) * 1986-01-31 1987-06-23 The United States Of America As Represented By The Secretary Of The Air Force Synthesis of Rf OTeF5

Also Published As

Publication number Publication date
JPS61215386A (ja) 1986-09-25
JPH07179351A (ja) 1995-07-18
EP0194393A2 (en) 1986-09-17
AU595487B2 (en) 1990-04-05
JP2528268B2 (ja) 1996-08-28
CN86101696A (zh) 1986-12-24
JPH0791286B2 (ja) 1995-10-04
CN1018640B (zh) 1992-10-14
US4761490A (en) 1988-08-02
DK487085D0 (da) 1985-10-23
AU5502290A (en) 1990-09-13
AU625922B2 (en) 1992-07-16
EP0194393B1 (en) 1990-06-13
DE3578176D1 (de) 1990-07-19
DK168890B1 (da) 1994-07-04
AU4912885A (en) 1986-09-18
DK9892A (da) 1992-01-27
DK487085A (da) 1986-09-16
DK9892D0 (da) 1992-01-27
DK168864B1 (da) 1994-06-27
EP0194393A3 (en) 1987-09-02
CA1327046C (en) 1994-02-15

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Legal Events

Date Code Title Description
KB Patent renewed
RH1 Patent not in force