IL77668A - Production of cholecalciferol derivatives and novel intermediates used therefor - Google Patents

Production of cholecalciferol derivatives and novel intermediates used therefor

Info

Publication number: IL77668A
Authority: IL; Israel
Prior art keywords: production; intermediates used; novel intermediates; used therefor; cholecalciferol derivatives
Prior art date: 1986-01-21

Application number

IL77668A

Other languages

English (en)

Inventor

Sterling Jeffrey

Weiner Ben-Zion

Barasch Dinora

Hirsch Danielle

Slovin Eliot

Original Assignee

Teva Pharma

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1986-01-21

Filing date

1986-01-21

Publication date

1989-03-31

1986-01-21 Application filed by Teva Pharma filed Critical Teva Pharma

1986-01-21 Priority to IL77668A priority Critical patent/IL77668A/xx

1986-12-01 Priority to ZA869054A priority patent/ZA869054B/xx

1986-12-02 Priority to AU66010/86A priority patent/AU590644B2/en

1986-12-15 Priority to DE8686117422T priority patent/DE3672251D1/de

1986-12-15 Priority to AT86117422T priority patent/ATE54138T1/de

1986-12-15 Priority to EP86117422A priority patent/EP0230600B1/de

1986-12-22 Priority to US06/944,921 priority patent/US4758382A/en

1987-01-20 Priority to JP62012153A priority patent/JPS62169762A/ja

1989-03-31 Publication of IL77668A publication Critical patent/IL77668A/xx

1991-11-01 Priority to JP3287990A priority patent/JP2505669B2/ja

Links

239000000543 intermediate Substances 0.000 title abstract 2
150000003704 vitamin D3 derivatives Chemical class 0.000 title 1
GMRQFYUYWCNGIN-NKMMMXOESA-N calcitriol Chemical compound C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@@H](CCCC(C)(C)O)C)=C\C=C1\C[C@@H](O)C[C@H](O)C1=C GMRQFYUYWCNGIN-NKMMMXOESA-N 0.000 abstract 2
238000000034 method Methods 0.000 abstract 2
238000002360 preparation method Methods 0.000 abstract 1
230000000707 stereoselective effect Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

IL77668A 1986-01-21 1986-01-21 Production of cholecalciferol derivatives and novel intermediates used therefor IL77668A (en)

Priority Applications (9)

Application Number	Priority Date	Filing Date	Title
IL77668A IL77668A (en)	1986-01-21	1986-01-21	Production of cholecalciferol derivatives and novel intermediates used therefor
ZA869054A ZA869054B (en)	1986-01-21	1986-12-01	Production of cholecalciferol derivatives and novel intermediates used therefor
AU66010/86A AU590644B2 (en)	1986-01-21	1986-12-02	Production of cholecalciferol derivatives and novel intermediates used therefor
DE8686117422T DE3672251D1 (de)	1986-01-21	1986-12-15	Herstellung von cholecalciferolderivaten und neue hierfuer verwendete zwischenprodukte.
AT86117422T ATE54138T1 (de)	1986-01-21	1986-12-15	Herstellung von cholecalciferolderivaten und neue hierfuer verwendete zwischenprodukte.
EP86117422A EP0230600B1 (de)	1986-01-21	1986-12-15	Herstellung von Cholecalciferolderivaten und neue hierfür verwendete Zwischenprodukte
US06/944,921 US4758382A (en)	1986-01-21	1986-12-22	Process for the stereospecific preparation of 24(R),25- and 24(S),25-dihydroxycholecalciferol and novel intermediates used therefor
JP62012153A JPS62169762A (ja)	1986-01-21	1987-01-20	コレカルシフェロール誘導体の製法
JP3287990A JP2505669B2 (ja)	1986-01-21	1991-11-01	コレカルシフェロ―ル誘導体の製造に用いる新規化合物およびその製法

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
IL77668A IL77668A (en)	1986-01-21	1986-01-21	Production of cholecalciferol derivatives and novel intermediates used therefor

Publications (1)

Publication Number	Publication Date
IL77668A true IL77668A (en)	1989-03-31

Family

ID=11056511

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL77668A IL77668A (en)	1986-01-21	1986-01-21	Production of cholecalciferol derivatives and novel intermediates used therefor

Country Status (8)

Country	Link
US (1)	US4758382A (de)
EP (1)	EP0230600B1 (de)
JP (2)	JPS62169762A (de)
AT (1)	ATE54138T1 (de)
AU (1)	AU590644B2 (de)
DE (1)	DE3672251D1 (de)
IL (1)	IL77668A (de)
ZA (1)	ZA869054B (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4927815A (en) *	1988-04-29	1990-05-22	Wisconsin Alumni Research Foundation	Compounds effective in inducing cell differentiation and process for preparing same
WO1990000560A1 (en) *	1988-07-05	1990-01-25	Kuraray Co., Ltd.	Steroid compounds
GB9007236D0 (en) *	1990-03-30	1990-05-30	Leo Pharm Prod Ltd	Chemical compounds
AU650751B2 (en) *	1991-05-28	1994-06-30	Wisconsin Alumni Research Foundation	Novel synthesis of 19-nor vitamin D compounds
ATE143007T1 (de) *	1991-07-05	1996-10-15	Duphar Int Res	Vitamin-d derivat, verfahren zu dessen herstellung sowie zwischenprodukte dafür
JP2876547B2 (ja) *	1992-06-23	1999-03-31	呉羽化学工業株式会社	抗クル病剤
AU5018893A (en) *	1992-08-17	1994-03-15	Alcon Laboratories, Inc.	Substituted hydrindanes for the treatment of angiogenesis-dependent diseases
US5464866A (en) *	1992-08-17	1995-11-07	Alcon Laboratories, Inc.	Substituted hydrindanes for the treatment of angiogenesis-dependent diseases
JP3306468B2 (ja) *	1997-10-30	2002-07-24	セレスティカ・ジャパン・イーエムエス株式会社	自動ハンダ付け機構及びその機構を用いる装置並びにそのハンダ付け方法
PL188697B1 (pl) *	1998-01-14	2005-03-31	Inst Farmaceutyczny	Sposób otrzymywania pochodnych cholekalcyferolu oraz nowe związki pośrednie
JP4752110B2 (ja) *	2000-12-25	2011-08-17	住友化学株式会社	トリフルオロプロペニル化合物の製造法
EP2144872A2 (de) *	2007-04-18	2010-01-20	Johns Hopkins University	Gering kalzämische und hoch antiproliferative calcitriol-analoga

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3715374A (en) *	1972-05-05	1973-02-06	Wisconsin Alumni Res Found	24,25-dihydroxycholecalciferol
US4069321A (en) *	1975-10-14	1978-01-17	Merck & Co., Inc.	Blocked cholecalciferol and dihydrotachysterol 3 derivatives
JPS5735599A (en) *	1980-08-05	1982-02-26	Chugai Pharmaceut Co Ltd	24,25-dihydroxycholestane and its preparation
US4442093A (en) *	1981-05-15	1984-04-10	Kureha Kagaku Kogyo Kabushiki Kaisha	Method for administering 24,25-dihydroxycholecalciferol to persons suffering from hypercalcemia
EP0115314B1 (de) *	1983-01-28	1988-06-08	F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft	Verfahren zur Herstellung von Cholecalciferolderivaten
US4508651A (en) *	1983-03-21	1985-04-02	Hoffmann-La Roche Inc.	Synthesis of 1α,25-dihydroxyergocalciferol
IL74264A (en) *	1984-02-08	1988-08-31	Hoffmann La Roche	Preparation of calciferol derivatives,certain such novel compounds and pharmaceutical compositions containing them

1986
- 1986-01-21 IL IL77668A patent/IL77668A/xx not_active IP Right Cessation
- 1986-12-01 ZA ZA869054A patent/ZA869054B/xx unknown
- 1986-12-02 AU AU66010/86A patent/AU590644B2/en not_active Ceased
- 1986-12-15 DE DE8686117422T patent/DE3672251D1/de not_active Expired - Lifetime
- 1986-12-15 EP EP86117422A patent/EP0230600B1/de not_active Expired - Lifetime
- 1986-12-15 AT AT86117422T patent/ATE54138T1/de not_active IP Right Cessation
- 1986-12-22 US US06/944,921 patent/US4758382A/en not_active Expired - Fee Related
1987
- 1987-01-20 JP JP62012153A patent/JPS62169762A/ja active Granted
1991
- 1991-11-01 JP JP3287990A patent/JP2505669B2/ja not_active Expired - Fee Related

Also Published As

Publication number	Publication date
AU6601086A (en)	1987-07-23
JPS62169762A (ja)	1987-07-25
JP2505669B2 (ja)	1996-06-12
ZA869054B (en)	1987-07-29
DE3672251D1 (de)	1990-08-02
EP0230600A1 (de)	1987-08-05
JPH0424346B2 (de)	1992-04-24
JPH054962A (ja)	1993-01-14
ATE54138T1 (de)	1990-07-15
US4758382A (en)	1988-07-19
AU590644B2 (en)	1989-11-09
EP0230600B1 (de)	1990-06-27

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Legal Events

Date	Code	Title	Description
1996-03-31	KB	Patent renewed
2000-12-06	RH	Patent void