IL79452A0 - Prostacyclins,their analogues or prostaglandins and thromboxane antagonists for the treatment of thrombotic and thrombo-embolic syndromes - Google Patents
Prostacyclins,their analogues or prostaglandins and thromboxane antagonists for the treatment of thrombotic and thrombo-embolic syndromesInfo
- Publication number
- IL79452A0 IL79452A0 IL79452A IL7945286A IL79452A0 IL 79452 A0 IL79452 A0 IL 79452A0 IL 79452 A IL79452 A IL 79452A IL 7945286 A IL7945286 A IL 7945286A IL 79452 A0 IL79452 A0 IL 79452A0
- Authority
- IL
- Israel
- Prior art keywords
- thrombo
- thrombotic
- treatment
- prostacyclins
- prostaglandins
- Prior art date
Links
- 230000009424 thromboembolic effect Effects 0.000 title abstract 2
- 230000001732 thrombotic effect Effects 0.000 title abstract 2
- 239000005557 antagonist Substances 0.000 title 1
- 229940094443 oxytocics prostaglandins Drugs 0.000 title 1
- 150000003815 prostacyclins Chemical class 0.000 title 1
- 150000003180 prostaglandins Chemical class 0.000 title 1
- 208000011580 syndromic disease Diseases 0.000 title 1
- RZWIIPASKMUIAC-VQTJNVASSA-N thromboxane Chemical compound CCCCCCCC[C@H]1OCCC[C@@H]1CCCCCCC RZWIIPASKMUIAC-VQTJNVASSA-N 0.000 title 1
- KAQKFAOMNZTLHT-VVUHWYTRSA-N epoprostenol Chemical compound O1C(=CCCCC(O)=O)C[C@@H]2[C@@H](/C=C/[C@@H](O)CCCCC)[C@H](O)C[C@@H]21 KAQKFAOMNZTLHT-VVUHWYTRSA-N 0.000 abstract 3
- 229940122202 Thromboxane receptor antagonist Drugs 0.000 abstract 2
- 239000002396 thromboxane receptor blocking agent Substances 0.000 abstract 2
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Combination products containing a prostaglandine (PG), a prostacycline (PC) or a prostacycline analogue (PCA) and a thromboxane receptor antagonist (TXAA), suited for joint use in the treatment of forms of thrombotic or thrombo-embolic illnesses.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19853526362 DE3526362A1 (en) | 1985-07-19 | 1985-07-19 | PROSTACYCLINE, YOUR ANALOGA OR PROSTAGLANDINE AND THROMBOXANANTAGONISTS FOR THE TREATMENT OF THROMBOTIC AND THROMBOEMBOLIC DISEASES |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL79452A0 true IL79452A0 (en) | 1986-10-31 |
Family
ID=6276548
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL79452A IL79452A0 (en) | 1985-07-19 | 1986-07-18 | Prostacyclins,their analogues or prostaglandins and thromboxane antagonists for the treatment of thrombotic and thrombo-embolic syndromes |
Country Status (13)
| Country | Link |
|---|---|
| EP (1) | EP0268581B1 (en) |
| JP (1) | JP2513656B2 (en) |
| AT (1) | ATE74507T1 (en) |
| AU (1) | AU602867B2 (en) |
| CA (1) | CA1273577A (en) |
| DE (2) | DE3526362A1 (en) |
| DK (1) | DK169017B1 (en) |
| ES (1) | ES2000090A6 (en) |
| GR (1) | GR861862B (en) |
| IE (1) | IE59338B1 (en) |
| IL (1) | IL79452A0 (en) |
| WO (1) | WO1987000434A1 (en) |
| ZA (1) | ZA865395B (en) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3717337A1 (en) * | 1987-05-22 | 1988-12-15 | Hoechst Ag | METHOD FOR DETECTING THE ANTIAGGREGATORY EFFECT OF VASOACTIVE SUBSTANCES, SPECIFICALLY OF PHOSPHODIESTERASE AND / OR CYCLOOXYGENASE INHIBITORS |
| AT393962B (en) * | 1987-10-22 | 1992-01-10 | Thomae Gmbh Dr K | Synergistic pharmaceutical combination with a content of a phosphodiesterase inhibitor and the use thereof |
| US4808627A (en) * | 1987-12-16 | 1989-02-28 | E. R. Squibb & Sons, Inc. | Method of preventing or treating toxemia in pregnancy using a thromboxane A2 receptor antagonist |
| US4820733A (en) * | 1988-03-07 | 1989-04-11 | E.R. Squibb & Sons, Inc. | Method of preventing or reducing platelet loss during extracorporeal circulation using a thromboxane A2 receptor antagonist |
| USH1139H (en) * | 1988-07-21 | 1993-02-02 | E. R. Squibb & Sons, Inc. | Combination of a calcium channel blocker and thromboxane A2 receptor antagonist or synthetase inhibitor and method for treating ischemia employing such combination |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1595056A (en) * | 1976-10-12 | 1981-08-05 | Wellcome Found | Pharmaceutical combination |
| SE443716B (en) * | 1977-05-20 | 1986-03-10 | Wellcome Found | SETTING TO PREPARE A PHARMACEUTICAL PREPARATION FOR INHIBITING BLOOD SPOT SEGREGATION CONTAINING PROSTACYCLINE OR DIHYDROPROSTACYCLINE AND A PHOSPHODIESTERATION INHIBITOR |
| CH637298A5 (en) * | 1978-01-01 | 1983-07-29 | Wellcome Found | Combination preparation counteracting the aggregation of blood platelets |
| HU191110B (en) * | 1982-10-01 | 1987-01-28 | Farmitala Carlo Erba Spa,It | Process for the production of the 15-cycloaliphatic derivatives 13,14-didehydro-carbaprostacyclines |
| US4456615A (en) * | 1982-10-25 | 1984-06-26 | E. R. Squibb & Sons, Inc. | 7-Oxabicycloheptane substituted amino prostaglandin analogs and their use in inhibiting platelet aggregation and bronchoconstriction |
| US4499296A (en) * | 1983-11-14 | 1985-02-12 | G. D. Searle & Co. | Omega cycloalkyl prostaglandins |
| US4579958A (en) * | 1983-12-23 | 1986-04-01 | G. D. Searle & Co. | 5-fluoro-3-oxa-6,7-didehydro-PGI1 compounds |
-
1985
- 1985-07-19 DE DE19853526362 patent/DE3526362A1/en not_active Ceased
-
1986
- 1986-06-20 WO PCT/DE1986/000260 patent/WO1987000434A1/en not_active Ceased
- 1986-06-20 EP EP86903257A patent/EP0268581B1/en not_active Expired - Lifetime
- 1986-06-20 DE DE8686903257T patent/DE3684785D1/en not_active Expired - Lifetime
- 1986-06-20 AT AT86903257T patent/ATE74507T1/en not_active IP Right Cessation
- 1986-06-20 AU AU59933/86A patent/AU602867B2/en not_active Ceased
- 1986-06-20 JP JP61503522A patent/JP2513656B2/en not_active Expired - Lifetime
- 1986-07-17 GR GR861862A patent/GR861862B/en unknown
- 1986-07-18 IL IL79452A patent/IL79452A0/en not_active IP Right Cessation
- 1986-07-18 ES ES8600380A patent/ES2000090A6/en not_active Expired
- 1986-07-18 ZA ZA865395A patent/ZA865395B/en unknown
- 1986-07-18 CA CA000514184A patent/CA1273577A/en not_active Expired - Lifetime
- 1986-07-21 IE IE192386A patent/IE59338B1/en not_active IP Right Cessation
-
1987
- 1987-03-17 DK DK136887A patent/DK169017B1/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| GR861862B (en) | 1986-11-17 |
| IE59338B1 (en) | 1994-02-09 |
| JP2513656B2 (en) | 1996-07-03 |
| ES2000090A6 (en) | 1987-12-01 |
| DK136887A (en) | 1987-03-17 |
| WO1987000434A1 (en) | 1987-01-29 |
| DK169017B1 (en) | 1994-08-01 |
| EP0268581B1 (en) | 1992-04-08 |
| DE3684785D1 (en) | 1992-05-14 |
| ZA865395B (en) | 1987-03-25 |
| ATE74507T1 (en) | 1992-04-15 |
| AU602867B2 (en) | 1990-11-01 |
| DK136887D0 (en) | 1987-03-17 |
| DE3526362A1 (en) | 1987-01-22 |
| IE861923L (en) | 1987-01-19 |
| EP0268581A1 (en) | 1988-06-01 |
| AU5993386A (en) | 1987-02-10 |
| CA1273577A (en) | 1990-09-04 |
| JPS63501360A (en) | 1988-05-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RH | Patent void |