IL80108A - Process for preparing 1,4-diisopropyl-2,5-diketopiperazines - Google Patents
Process for preparing 1,4-diisopropyl-2,5-diketopiperazinesInfo
- Publication number
- IL80108A IL80108A IL80108A IL8010886A IL80108A IL 80108 A IL80108 A IL 80108A IL 80108 A IL80108 A IL 80108A IL 8010886 A IL8010886 A IL 8010886A IL 80108 A IL80108 A IL 80108A
- Authority
- IL
- Israel
- Prior art keywords
- diketopiperazines
- diisopropyl
- preparing
- unsubstituted
- substituted
- Prior art date
Links
- LCTYQXDHTHVMLH-UHFFFAOYSA-N 1,4-di(propan-2-yl)piperazine-2,5-dione Chemical class CC(C)N1CC(=O)N(C(C)C)CC1=O LCTYQXDHTHVMLH-UHFFFAOYSA-N 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- BEBCJVAWIBVWNZ-UHFFFAOYSA-N glycinamide Chemical class NCC(N)=O BEBCJVAWIBVWNZ-UHFFFAOYSA-N 0.000 abstract 1
- -1 haloacetyl halide Chemical class 0.000 abstract 1
- 230000000269 nucleophilic effect Effects 0.000 abstract 1
- BXRNXXXXHLBUKK-UHFFFAOYSA-N piperazine-2,5-dione Chemical class O=C1CNC(=O)CN1 BXRNXXXXHLBUKK-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/06—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members
- C07D241/08—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/778,817 US4694081A (en) | 1985-09-23 | 1985-09-23 | Process to prepare 2,5-diketopiperazines |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL80108A0 IL80108A0 (en) | 1986-12-31 |
| IL80108A true IL80108A (en) | 1991-07-18 |
Family
ID=25114475
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL80108A IL80108A (en) | 1985-09-23 | 1986-09-22 | Process for preparing 1,4-diisopropyl-2,5-diketopiperazines |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US4694081A (de) |
| EP (1) | EP0216746B1 (de) |
| JP (1) | JPS6272676A (de) |
| AT (1) | ATE57694T1 (de) |
| AU (1) | AU588626B2 (de) |
| CA (1) | CA1257266A (de) |
| DE (1) | DE3675134D1 (de) |
| HU (1) | HU196382B (de) |
| IL (1) | IL80108A (de) |
| ZA (1) | ZA867212B (de) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4806538A (en) * | 1984-11-02 | 1989-02-21 | Fujisawa Pharmaceutical Co., Ltd. | Piperazine compound as PAF-antagonist |
| US4992552A (en) * | 1988-08-31 | 1991-02-12 | Eastman Kodak Company | Process for preparation of amino acids |
| JPH04234374A (ja) * | 1990-12-27 | 1992-08-24 | Ajinomoto Co Inc | ジケトピペラジン誘導体の製造方法 |
| US5208375A (en) * | 1991-07-02 | 1993-05-04 | Mallinckrodt Medical, Inc. | Compositions for magnetic resonance imaging |
| US5874589A (en) * | 1997-07-18 | 1999-02-23 | Glaxo Wellcome, Inc. | Methods for synthesizing diverse collections of tetramic acids and derivatives thereof |
| CN100553636C (zh) | 2000-08-04 | 2009-10-28 | Dmi生物科学公司 | 二酮基哌嗪和包含它们的组合物的使用方法 |
| GB2382346B (en) * | 2000-08-04 | 2004-08-11 | Dmi Biosciences Inc | Method of synthesizing diketopiperazines |
| KR100542820B1 (ko) * | 2002-09-17 | 2006-01-20 | 이재호 | 옥사릴 클로라이드를 이용한 1-에틸-2,3-디옥소피페라진의제조방법 |
| WO2004030522A2 (en) * | 2002-10-02 | 2004-04-15 | Dmi Biosciences, Inc. | Diagnosis and monitoring of diseases |
| EP2517718B1 (de) | 2003-05-15 | 2016-03-02 | Ampio Pharmaceuticals, Inc. | Behandlung von T-Zell-vermittelten Krankheiten |
| JP5856843B2 (ja) | 2008-05-27 | 2016-02-10 | アンピオ ファーマシューティカルズ，インコーポレイテッド | ジケトピペラジンを用いた医薬組成物 |
| US8116047B2 (en) * | 2008-12-18 | 2012-02-14 | Sandisk Technologies Inc. | Electrostatic discharge protective circuit having rise time detector and discharge sustaining circuitry |
| KR101278140B1 (ko) * | 2010-07-15 | 2013-06-27 | 공주대학교 산학협력단 | 2,5-다이케토피페라진 유도체를 활성성분으로 포함하는 농업용 약제 |
| EP2613786A4 (de) | 2010-09-07 | 2013-10-23 | Dmi Acquisition Corp | Behandlung von erkrankungen |
| MY172699A (en) | 2011-10-10 | 2019-12-10 | Ampio Pharmaceuticals Inc | Implantable medical devices with increased immune tolerance, and methods for making and implanting |
| EA028343B1 (ru) | 2011-10-10 | 2017-11-30 | Ампио Фармасьютикалз, Инк. | Лечение дегенеративного заболевания сустава |
| EP2771007B1 (de) | 2011-10-28 | 2018-04-04 | Ampio Pharmaceuticals, Inc. | Behandlung von rhinitis |
| BR112015020469A2 (pt) | 2013-03-15 | 2020-01-28 | Ampio Pharmaceuticals Inc | Usos de da-dkp, composição e método para fornecimento de células-tronco a umindivíduo |
| RU2736513C2 (ru) | 2014-08-18 | 2020-11-17 | Ампио Фармасьютикалз, Инк. | Лечение патологических состояний суставов |
| EP3310375A4 (de) | 2015-06-22 | 2019-02-20 | Ampio Pharmaceuticals, Inc. | Verwendung von niedermolekularen fraktionen von humanem serumalbumin bei der behandlung von erkrankungen |
| WO2021195265A1 (en) | 2020-03-24 | 2021-09-30 | Ampio Pharmaceuticals, Inc. | Methods for treating diseases associated with respiratory viruses |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2913496A (en) * | 1957-06-07 | 1959-11-17 | Du Pont | N-(2-hydroxyethyl)-n'-pentenyl-ethylenediamine |
| DE1189553B (de) * | 1962-08-09 | 1965-03-25 | Degussa | Verfahren zur Herstellung von racemischen und optisch aktiven Piperazinderivaten |
| US4140791A (en) * | 1978-05-30 | 1979-02-20 | Chevron Research Company | 1,4-Di-(2,6-dimethylphenyl)-2,5-piperazinedione and its fungicidal use |
| JPS5618969A (en) * | 1979-07-24 | 1981-02-23 | Toyama Chem Co Ltd | Novel 1-(4-aminobenzyl)-2,3-dioxopiperazine derivative, its acid addition salt, and their preparation |
| US4400330A (en) * | 1982-07-29 | 1983-08-23 | Stauffer Chemical Company | Method for preparation of N-phosphonomethylglycine |
| GB8427735D0 (en) * | 1984-11-02 | 1984-12-12 | Fujisawa Pharmaceutical Co | Piperazine compound |
| US4804499A (en) * | 1985-09-23 | 1989-02-14 | Monsanto Company | Process for the preparation of N-substituted aminomethylphosphonic acids |
| US4694082A (en) * | 1985-09-23 | 1987-09-15 | Monsanto Company | Compound 1,4-diisopropyl-2,5-diketopiperazine |
-
1985
- 1985-09-23 US US06/778,817 patent/US4694081A/en not_active Expired - Fee Related
-
1986
- 1986-09-22 JP JP61222275A patent/JPS6272676A/ja active Pending
- 1986-09-22 AT AT86870133T patent/ATE57694T1/de active
- 1986-09-22 EP EP86870133A patent/EP0216746B1/de not_active Expired - Lifetime
- 1986-09-22 HU HU864016A patent/HU196382B/hu not_active IP Right Cessation
- 1986-09-22 IL IL80108A patent/IL80108A/xx unknown
- 1986-09-22 ZA ZA867212A patent/ZA867212B/xx unknown
- 1986-09-22 AU AU63034/86A patent/AU588626B2/en not_active Ceased
- 1986-09-22 CA CA000518770A patent/CA1257266A/en not_active Expired
- 1986-09-22 DE DE8686870133T patent/DE3675134D1/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| AU6303486A (en) | 1987-03-26 |
| CA1257266A (en) | 1989-07-11 |
| DE3675134D1 (de) | 1990-11-29 |
| EP0216746A2 (de) | 1987-04-01 |
| US4694081A (en) | 1987-09-15 |
| ZA867212B (en) | 1987-08-26 |
| AU588626B2 (en) | 1989-09-21 |
| ATE57694T1 (de) | 1990-11-15 |
| EP0216746B1 (de) | 1990-10-24 |
| EP0216746A3 (en) | 1987-09-09 |
| HUT41748A (en) | 1987-05-28 |
| HU196382B (en) | 1988-11-28 |
| JPS6272676A (ja) | 1987-04-03 |
| IL80108A0 (en) | 1986-12-31 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IL80108A (en) | Process for preparing 1,4-diisopropyl-2,5-diketopiperazines | |
| DE3569112D1 (en) | 4,5-dihydro-4-oxo-2- û(2-trans-phenylcyclopropyl)amino¨-3-furancarboxylic acids and derivatives thereof | |
| EP0195402A3 (en) | Bis(hydroxyphthalimide) and process for preparing the same, and process for preparing polyesterimide by the use thereof | |
| EP0218970A3 (en) | Chiral rhodium-diphosphine complexes for asymmetrical hydrogenation | |
| GEP19970662B (en) | Method of alkylanilinofumarate synthesis | |
| ES8504764A1 (es) | Procedimiento para preparar piridil y quinolil-imidazolinonas. | |
| YU4286A (en) | PROCESS FOR PREPARING NEW 12-AMINOPYRIDAZINO(4',5'3,4(PYROLO)2,1-a)IZOCHYNOLINES | |
| EP0234940A3 (en) | Novel derivatives based upon pyrido-menadione adducts and uses thereof | |
| ES2002161A6 (es) | Procedimiento para preparar 1,3-diazabiciclo (4.4.0)dec-2-en-4-onas antiarritmicas | |
| EP0119091A3 (en) | 2,2-diethoxypropionic acid derivatives | |
| ES8801684A1 (es) | Un procedimiento para la preparacion de un derivado de ciclopentadieno polimerico. | |
| AU3441684A (en) | Bis(3,5-dioxopiperazine)-ethane derivatives | |
| SU1250153A1 (ru) | Устройство для сверхвысокочастотного нагрева | |
| SU1233456A1 (ru) | Способ получения замещенных n-[(1,3,5-триазин-2-ил)аминокарбонил]бензолсульфонамидов | |
| SU1258083A1 (ru) | Сталь | |
| Tattersall | Dislocation Thomas Kinsella's exploration in his poetry of his sense of alienation from woman. | |
| SU1269465A1 (ru) | Способ получения 2-анилино-7-гидрокси-6н-1,3,4-тиадиазепинов | |
| SU1218889A2 (ru) | Магнитогидродинамическая машина | |
| IL71763A0 (en) | Cyclohexanecarboxylic acid derivatives and their preparation | |
| IL82458A0 (en) | Novel derivatives based upon pyrido-menadione adducts and uses thereof | |
| SU1216944A1 (ru) | Способ получения 2,6-ди-трет-бутилфенола | |
| SU1111454A1 (ru) | Способ получения (4,6-дизамещенный пиримидинил-2)тиофанийбромидов | |
| CA54209S (en) | Iron base | |
| SU1271111A1 (ru) | Сплав на основе алюминия | |
| CA55572S (en) | Pressing iron |