IL81006A0 - Sulfinyl and sulfonyl substituted-3-benzazepines - Google Patents

Sulfinyl and sulfonyl substituted-3-benzazepines

Info

Publication number
IL81006A0
IL81006A0 IL81006A IL8100686A IL81006A0 IL 81006 A0 IL81006 A0 IL 81006A0 IL 81006 A IL81006 A IL 81006A IL 8100686 A IL8100686 A IL 8100686A IL 81006 A0 IL81006 A0 IL 81006A0
Authority
IL
Israel
Prior art keywords
c6alkyl
hydrogen
compounds
benzazepines
sulfinyl
Prior art date
Application number
IL81006A
Other languages
English (en)
Original Assignee
Smithkline Beckman Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beckman Corp filed Critical Smithkline Beckman Corp
Publication of IL81006A0 publication Critical patent/IL81006A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/16—Benzazepines; Hydrogenated benzazepines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/06—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to ring carbon atoms
    • C07D233/08—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to ring carbon atoms with alkyl radicals, containing more than four carbon atoms, directly attached to ring carbon atoms
    • C07D233/12—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to ring carbon atoms with alkyl radicals, containing more than four carbon atoms, directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D233/16—Radicals substituted by nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Thermal Transfer Or Thermal Recording In General (AREA)
  • Hydrogenated Pyridines (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
IL81006A 1985-12-20 1986-12-17 Sulfinyl and sulfonyl substituted-3-benzazepines IL81006A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/811,789 US4659706A (en) 1985-12-20 1985-12-20 Sulfinyl and sulfonyl substituted 3-benzazepines

Publications (1)

Publication Number Publication Date
IL81006A0 true IL81006A0 (en) 1987-03-31

Family

ID=25207582

Family Applications (1)

Application Number Title Priority Date Filing Date
IL81006A IL81006A0 (en) 1985-12-20 1986-12-17 Sulfinyl and sulfonyl substituted-3-benzazepines

Country Status (17)

Country Link
US (1) US4659706A (de)
EP (1) EP0229510B1 (de)
JP (1) JPS62158255A (de)
KR (1) KR870006007A (de)
CN (1) CN86108627A (de)
AT (1) ATE53385T1 (de)
AU (1) AU589240B2 (de)
CA (1) CA1263384A (de)
DE (1) DE3671746D1 (de)
DK (1) DK610686A (de)
FI (1) FI865220L (de)
HU (1) HUT43826A (de)
IL (1) IL81006A0 (de)
NO (1) NO865203L (de)
PH (1) PH22358A (de)
PT (1) PT83929B (de)
ZA (1) ZA869501B (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0285287A3 (de) * 1987-03-23 1990-08-16 Smithkline Beecham Corporation Verwendung von 3-Benzazepinen zur Behandlung von gastrointestinalen Mobilitätsstörungen
WO1993000094A2 (en) * 1991-06-21 1993-01-07 Smithkline Beecham Plc Use of tetrahydrobenzazepine derivatives for the treatment of portal hypertension and migraine
AU755119B2 (en) 1998-09-18 2002-12-05 Alcon Laboratories, Inc. Serotonergic 5HT2 agonists for treating glaucoma
CA2347095A1 (en) * 1998-10-16 2000-04-27 Takeda Chemical Industries, Ltd. Nitrogen-containing condensed heterocyclic derivatives, their production and agent
KR100480782B1 (ko) * 2002-10-26 2005-04-07 삼성에스디아이 주식회사 연료전지 단위체, 그 제조방법 및 상기 연료전지 단위체를채용한 연료전지
US20060073172A1 (en) * 2004-10-01 2006-04-06 Schneider L W Stabilized ophthalmic solution for the treatment of glaucoma and lowering intraocular pressure

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3483185A (en) * 1966-08-16 1969-12-09 American Home Prod N-substituted 2,3,4,5-tetrahydro-1h-3-benzazepines
CA974989A (en) * 1968-03-11 1975-09-23 Wallace And Tiernan Inc. Process for preparing 1,2,4,5-tetrahydro-3h,3-benzazepines and products obtained thereby
DE1921737A1 (de) * 1969-04-29 1970-11-12 Bayer Ag Heterocyclische Acylreste enthaltende Sulfonylharnstoffe und Sulfonylsemicarbazide mit antidiabetischer Wirkung
US3671519A (en) * 1969-07-14 1972-06-20 American Home Prod N-substituted 2,3,4,5,-tetrahydro-1h-3-benzazepines
US3725388A (en) * 1970-06-25 1973-04-03 Boehringer Sohn Ingelheim N-acyl-7-(n{41 -cycloalkyl-ureido-n{40 -sulfonyl)-isoquinolines and -benzazepines and alkali metal salts thereof
CH593263A5 (de) * 1974-02-22 1977-11-30 Hoffmann La Roche
US4206210A (en) * 1977-01-19 1980-06-03 Smithkline Corporation Alkylthio-7,8-dihdroxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepines having dopaminergic activity
US4265890A (en) * 1978-07-07 1981-05-05 Smithkline Corporation 6-Phenyl thio- and 6-cyclohexyl thio-2,3,4,5-tetrahydro-1H-3-benzazepines
US4469634A (en) * 1982-07-29 1984-09-04 Smithkline Beckman Corporation Allyloxy- and allylthio-2,3,4,5-tetrahydro-1H-3-benzazepines

Also Published As

Publication number Publication date
FI865220A7 (fi) 1987-06-21
PH22358A (en) 1988-08-12
ZA869501B (en) 1987-08-26
CN86108627A (zh) 1987-07-22
KR870006007A (ko) 1987-07-08
AU6677986A (en) 1987-06-25
DK610686D0 (da) 1986-12-17
CA1263384A (en) 1989-11-28
PT83929A (en) 1987-01-01
PT83929B (pt) 1989-05-12
HUT43826A (en) 1987-12-28
DK610686A (da) 1987-06-21
FI865220L (fi) 1987-06-21
DE3671746D1 (de) 1990-07-12
EP0229510B1 (de) 1990-06-06
AU589240B2 (en) 1989-10-05
NO865203L (no) 1987-06-22
EP0229510A1 (de) 1987-07-22
NO865203D0 (no) 1986-12-19
ATE53385T1 (de) 1990-06-15
FI865220A0 (fi) 1986-12-19
US4659706A (en) 1987-04-21
JPS62158255A (ja) 1987-07-14

Similar Documents

Publication Publication Date Title
PH25508A (en) Substituted quinazoline derivatives for use in gastrointestinal diseases
AU589240B2 (en) Sulfinyl and sulfonyl substituted-3-benzazepine
AU584235B2 (en) New tricyclic compounds, processes for the preparation thereof and pharmaceutical compositions containing them
FI92320B (fi) Menetelmä uusien terapeuttisesti käyttökelpoisten bisfenyylialkyylipiperatsiinijohdannaisten valmistamiseksi
ES2019840A6 (es) Procedimiento para preparar nuevos derivados de tieno-triazolo-diazepina.
AU586724B2 (en) 1-phenyl-3-benzazepines
EP0302757A3 (de) Antiemetisch wirksame Serotonin-Depletoren
ZA881561B (en) Substituted pyridine-2,4-dicarboxylic acid derivatives,processes for their preparation,the use thereof and medicaments based on these compounds
DK492989D0 (da) Aminopyrrolidinon, farmaceutisk praeparat indeholdende en saadan forbindelse og fremgangsmaade til fremstilling deraf
DK0401093T3 (da) Hidtil ukendte pyrrolidonderivater, fremgangsmåde til fremstilling heraf og farmaceutiske midler indeholdende disse
HUT71127A (en) 2,3,4,5-tetrahydro-1h-3-benzodiazepines and pharmaceutically acceptable acid additional salts thereof, pharmaceutical compositions containing them and process for their preparation
EP0276805A3 (en) Substituted 3-phenyl-7h-thiazoloû3,2-b¨û1,2,4¨triazin-7-ones, processes for their preparation, medicaments containing them and their use as well as some of the intermediates obtained during the preparation of said compounds
ES8802506A1 (es) Procedimiento para preparar derivados de fluoralcanos.
NZ216741A (en) 6-oxo-1,6-dihydropyridazines and pharmaceutical compositions
GR850484B (de)
PT82535B (en) Pharmacologically active propionylanilides
GB9926301D0 (en) Novel compounds