IL82103A - Cell line producing aids viral antigens without producing infectious virus particles and method and kit for the detection of aids antibodies in a sample - Google Patents
Cell line producing aids viral antigens without producing infectious virus particles and method and kit for the detection of aids antibodies in a sampleInfo
- Publication number
- IL82103A IL82103A IL82103A IL8210387A IL82103A IL 82103 A IL82103 A IL 82103A IL 82103 A IL82103 A IL 82103A IL 8210387 A IL8210387 A IL 8210387A IL 82103 A IL82103 A IL 82103A
- Authority
- IL
- Israel
- Prior art keywords
- aids
- infectious virus
- producing
- cells
- kit
- Prior art date
Links
- 208000015181 infectious disease Diseases 0.000 title abstract 4
- 241000700605 Viruses Species 0.000 title abstract 3
- 230000002458 infectious effect Effects 0.000 title abstract 3
- 239000000427 antigen Substances 0.000 title 1
- 102000036639 antigens Human genes 0.000 title 1
- 108091007433 antigens Proteins 0.000 title 1
- 238000001514 detection method Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 239000002245 particle Substances 0.000 title 1
- 230000003612 virological effect Effects 0.000 title 1
- 208000030507 AIDS Diseases 0.000 abstract 2
- 208000005074 Retroviridae Infections Diseases 0.000 abstract 1
- 108010087302 Viral Structural Proteins Proteins 0.000 abstract 1
- 230000001154 acute effect Effects 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 230000001413 cellular effect Effects 0.000 abstract 1
- 239000003153 chemical reaction reagent Substances 0.000 abstract 1
- 230000002950 deficient Effects 0.000 abstract 1
- 238000010790 dilution Methods 0.000 abstract 1
- 239000012895 dilution Substances 0.000 abstract 1
- 238000003119 immunoblot Methods 0.000 abstract 1
- 230000001566 pro-viral effect Effects 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
- 241001430294 unidentified retrovirus Species 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
- C12Q1/701—Specific hybridization probes
- C12Q1/702—Specific hybridization probes for retroviruses
- C12Q1/703—Viruses associated with AIDS
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16061—Methods of inactivation or attenuation
- C12N2740/16062—Methods of inactivation or attenuation by genetic engineering
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16111—Human Immunodeficiency Virus, HIV concerning HIV env
- C12N2740/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/81—Packaged device or kit
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/807—Apparatus included in process claim, e.g. physical support structures
- Y10S436/808—Automated or kit
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/811—Test for named disease, body condition or organ function
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/811—Test for named disease, body condition or organ function
- Y10S436/813—Cancer
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/808—Materials and products related to genetic engineering or hybrid or fused cell technology, e.g. hybridoma, monoclonal products
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Virology (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- General Engineering & Computer Science (AREA)
- AIDS & HIV (AREA)
- Analytical Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Physics & Mathematics (AREA)
- Biomedical Technology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/849,059 US4752565A (en) | 1986-04-07 | 1986-04-07 | Cell line producing AIDS viral antigens without producing infectious virus particles |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL82103A0 IL82103A0 (en) | 1987-10-30 |
| IL82103A true IL82103A (en) | 1991-01-31 |
Family
ID=25304965
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL82103A IL82103A (en) | 1986-04-07 | 1987-04-03 | Cell line producing aids viral antigens without producing infectious virus particles and method and kit for the detection of aids antibodies in a sample |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US4752565A (fr) |
| EP (1) | EP0241239B1 (fr) |
| JP (1) | JP2691184B2 (fr) |
| AT (1) | ATE114711T1 (fr) |
| AU (1) | AU597654B2 (fr) |
| CA (1) | CA1286619C (fr) |
| DE (1) | DE3750782T2 (fr) |
| IE (1) | IE67276B1 (fr) |
| IL (1) | IL82103A (fr) |
| NZ (1) | NZ219897A (fr) |
| WO (1) | WO1987006258A1 (fr) |
Families Citing this family (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4843011A (en) * | 1985-08-01 | 1989-06-27 | Akzo N.V. | Monoclonal antibodies for binding HTLV-III proteins, and cell lines for their production |
| FR2625100A2 (fr) * | 1986-03-13 | 1989-06-30 | Lurhuma Zirimwabagabo | Utilisation d'antigenes pour la preparation de vaccins, proteine rendue immunogene et composition pharmaceutique la comportant |
| US4935372A (en) * | 1986-05-20 | 1990-06-19 | Dana Farber Cancer Institute | Art nucleotide segments, vectors, cell lines methods of preparation and use |
| SE8605535L (sv) * | 1986-12-22 | 1988-06-23 | Birgitta Asjo | Cellsystem, dess framstellning och anvendning |
| SE8701765L (sv) * | 1987-04-28 | 1988-10-29 | Statens Bakteriologiska Lab | Analysmetod och medel foer denna |
| US4931393A (en) * | 1987-09-14 | 1990-06-05 | The United States Of America As Represented By The Department Of Health And Human Services | Non-infectious mutant clone of HIV |
| US5019510A (en) * | 1987-10-28 | 1991-05-28 | Institut Pasteur | Isolation, molecular cloning and sequencing of an HIV-1 isolate from a Gabonese donor |
| JPH01120284A (ja) * | 1987-11-05 | 1989-05-12 | Shiro Kato | Hiv不完全粒子および該製造方法 |
| US6569679B1 (en) | 1988-03-21 | 2003-05-27 | Chiron Corporation | Producer cell that generates adenoviral vectors encoding a cytokine and a conditionally lethal gene |
| US6133029A (en) | 1988-03-21 | 2000-10-17 | Chiron Corporation | Replication defective viral vectors for infecting human cells |
| US5997859A (en) * | 1988-03-21 | 1999-12-07 | Chiron Corporation | Method for treating a metastatic carcinoma using a conditionally lethal gene |
| US5716826A (en) * | 1988-03-21 | 1998-02-10 | Chiron Viagene, Inc. | Recombinant retroviruses |
| US5747324A (en) * | 1988-06-10 | 1998-05-05 | Therion Biologics Corporation | Self-assembled, defective, non-self-propagating lentivirus particles |
| US5614404A (en) * | 1988-06-10 | 1997-03-25 | Theriod Biologics, Incorporated | Self-assembled, defective, non-self-propagating lentivirus particles |
| US5631154A (en) * | 1988-06-10 | 1997-05-20 | Therion Biologics, Incorporated | Self assembled, defective, non-self-propagating lentivirus particles |
| US5089479A (en) * | 1988-11-28 | 1992-02-18 | Krivan Howard C | Adhesion of mycoplasma pneumoniae and mycoplasma hominus to sulfatide |
| JP2852431B2 (ja) * | 1988-12-07 | 1999-02-03 | 財団法人阪大微生物病研究会 | レトロウイルスのプロテアーゼ、逆転写酵素及びエンドヌクレアーゼ、並びにこれ等の酵素の製法 |
| JP3140757B2 (ja) * | 1989-02-06 | 2001-03-05 | デイナ・フアーバー・キヤンサー・インステイテユート | パッケージング欠陥hivプロウイルス、細胞系及びその使用 |
| JP3034025B2 (ja) * | 1989-06-01 | 2000-04-17 | アプライド・バイオテクノロジー・インコーポレーテツド | 自己アセンブルド欠損非自己増殖性ウイルス粒子 |
| GB8923123D0 (en) * | 1989-10-13 | 1989-11-29 | Connaught Lab | A vaccine for human immunodeficiency virus |
| JPH05501201A (ja) * | 1989-10-16 | 1993-03-11 | ホワイトヘツド・インスチチユート・フオー・バイオメデイカル・リサーチ | 非感染性hiv―1粒子およびそれらの使用 |
| US5861282A (en) * | 1989-10-16 | 1999-01-19 | Whitehead Institute For Biomedical Research | Non-infectious HIV particles and uses therefor |
| JP3203599B2 (ja) * | 1989-10-24 | 2001-08-27 | カイロン コーポレイション | 感染性タンパク質デリバリーシステム |
| EP0502105A4 (en) * | 1989-11-20 | 1993-02-24 | Oncogen Limited Partnership | Non-replicating recombinant-made retroviral particles used as antiviral agents and immunogens |
| CA2059317A1 (fr) * | 1991-01-15 | 1992-07-16 | Yi Zeng | Essai immunoenzymatique pour la detection des anticorps diriges contre le vih-1 |
| US6268211B1 (en) * | 1991-08-20 | 2001-07-31 | L'institut De Recherches Cliniques De Montreal | Non-infectious HIV transgene |
| JPH07500490A (ja) * | 1991-05-15 | 1995-01-19 | ランスティチュ ドュ レシェルシュ クリニーク ドュ モントリオール | 非感染性hivゲノムを保持するトランスジェニック非ヒト動物 |
| US5470572A (en) * | 1993-07-16 | 1995-11-28 | University Of Puerto Rico | Non-infectious simian immunodeficiency virus particles produced by cell line CRL 11393 |
| WO1995014091A2 (fr) | 1993-11-18 | 1995-05-26 | Chiron Viagene, Inc. | Compositions et procedes d'utilisation de genes a pouvoir letal conditionnel |
| WO1995016040A2 (fr) * | 1993-12-10 | 1995-06-15 | The Canadian Red Cross Society | Titrage par immunofluorescence concernant la detection d'anticorps et utilisant des antigenes recombines sous forme non soluble |
| US5888814A (en) * | 1994-06-06 | 1999-03-30 | Chiron Corporation | Recombinant host cells encoding TNF proteins |
| US5733781A (en) | 1994-07-19 | 1998-03-31 | Gen-Probe Incorporated | Oligonucleotides and methods for inhibiting propagation of human immunodeficiency virus |
| US6410725B1 (en) * | 1999-02-26 | 2002-06-25 | Myriad Genetics Inc. | Method for extracting DNA from dried specimens |
| CN1332038C (zh) * | 2001-08-24 | 2007-08-15 | 日本油脂株式会社 | 单链核酸分子间错配的判断方法 |
| CA2923833C (fr) | 2013-10-22 | 2020-02-25 | F. Hoffmann-La Roche Ag | Procede permettant de mesurer des particules virales exemptes de cellules a partir de taches de sang seche |
| CN116676367A (zh) * | 2023-05-31 | 2023-09-01 | 中国疾病预防控制中心性病艾滋病预防控制中心 | 一种基于8e5细胞的hiv-1病毒载量检测能力验证质控品的制备方法及应用 |
| CN118792258A (zh) * | 2024-06-29 | 2024-10-18 | 中国疾病预防控制中心性病艾滋病预防控制中心 | 一种含有逆转录酶抑制剂耐药位点q151m的细胞株、构建方法与应用 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2480780B1 (fr) * | 1980-04-22 | 1985-12-06 | Pasteur Institut | Procede de transformation de cellules, notamment eucaryotes, par un adn circulaire tel que celui du virus de l'hepatite b et preparations contenant les produits d'expression desdits adn |
| US4652599A (en) * | 1984-04-23 | 1987-03-24 | The United States Of America As Represented By The Department Of Health And Human Services | Method of continuous production of retroviruses (HTLV-III) from patients with AIDS and pre-AIDS using permissive cells |
| US4520113A (en) * | 1984-04-23 | 1985-05-28 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Serological detection of antibodies to HTLV-III in sera of patients with AIDS and pre-AIDS conditions |
| DE3436682A1 (de) * | 1984-10-05 | 1986-04-10 | Hoechst Ag, 6230 Frankfurt | Schlauchfoermige verpackungshuelle, insbesondere wursthuelle, auf polyamidbasis |
-
1986
- 1986-04-07 US US06/849,059 patent/US4752565A/en not_active Expired - Lifetime
-
1987
- 1987-04-03 EP EP87302934A patent/EP0241239B1/fr not_active Expired - Lifetime
- 1987-04-03 AT AT87302934T patent/ATE114711T1/de not_active IP Right Cessation
- 1987-04-03 DE DE3750782T patent/DE3750782T2/de not_active Expired - Lifetime
- 1987-04-03 IL IL82103A patent/IL82103A/xx not_active IP Right Cessation
- 1987-04-06 JP JP62502365A patent/JP2691184B2/ja not_active Expired - Lifetime
- 1987-04-06 CA CA000533899A patent/CA1286619C/fr not_active Expired - Lifetime
- 1987-04-06 AU AU72827/87A patent/AU597654B2/en not_active Expired
- 1987-04-06 IE IE88387A patent/IE67276B1/en not_active IP Right Cessation
- 1987-04-06 WO PCT/US1987/000742 patent/WO1987006258A1/fr not_active Ceased
- 1987-04-07 NZ NZ219897A patent/NZ219897A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA1286619C (fr) | 1991-07-23 |
| ATE114711T1 (de) | 1994-12-15 |
| EP0241239A2 (fr) | 1987-10-14 |
| EP0241239B1 (fr) | 1994-11-30 |
| AU7282787A (en) | 1987-11-09 |
| IE870883L (en) | 1987-10-07 |
| JPS63500985A (ja) | 1988-04-14 |
| DE3750782T2 (de) | 1995-04-13 |
| AU597654B2 (en) | 1990-06-07 |
| EP0241239A3 (en) | 1989-08-16 |
| IE67276B1 (en) | 1996-03-20 |
| JP2691184B2 (ja) | 1997-12-17 |
| WO1987006258A1 (fr) | 1987-10-22 |
| US4752565A (en) | 1988-06-21 |
| DE3750782D1 (de) | 1995-01-12 |
| NZ219897A (en) | 1990-04-26 |
| IL82103A0 (en) | 1987-10-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| KB | Patent renewed | ||
| KB | Patent renewed | ||
| KB | Patent renewed | ||
| EXP | Patent expired |