IL83420A - Process for the preparation of stereospecific 4-halomethyl-azetidin-2-ones from beta-ypsilon-unsaturated o-acylhydroxamates - Google Patents

Process for the preparation of stereospecific 4-halomethyl-azetidin-2-ones from beta-ypsilon-unsaturated o-acylhydroxamates

Info

Publication number: IL83420A
Authority: IL; Israel
Prior art keywords: ones; beta; unsaturated; lower alkyl; acylhydroxamates
Prior art date: 1986-08-06

Application number

IL83420A

Other languages

English (en)

Other versions

IL83420A0 (en

Original Assignee

Univ Norte Dame Du Lac

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1986-08-06

Filing date

1987-08-03

Publication date

1992-07-15

1987-08-03 Application filed by Univ Norte Dame Du Lac filed Critical Univ Norte Dame Du Lac

1988-01-31 Publication of IL83420A0 publication Critical patent/IL83420A0/xx

1992-07-15 Publication of IL83420A publication Critical patent/IL83420A/xx

Links

230000000707 stereoselective effect Effects 0.000 title 1
125000000217 alkyl group Chemical group 0.000 abstract 4
229910052736 halogen Inorganic materials 0.000 abstract 2
150000002367 halogens Chemical class 0.000 abstract 2
DYLIWHYUXAJDOJ-OWOJBTEDSA-N (e)-4-(6-aminopurin-9-yl)but-2-en-1-ol Chemical compound NC1=NC=NC2=C1N=CN2C\C=C\CO DYLIWHYUXAJDOJ-OWOJBTEDSA-N 0.000 abstract 1
125000003545 alkoxy group Chemical group 0.000 abstract 1
125000003277 amino group Chemical group 0.000 abstract 1
125000000051 benzyloxy group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])O* 0.000 abstract 1
230000003115 biocidal effect Effects 0.000 abstract 1
239000003153 chemical reaction reagent Substances 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
125000002485 formyl group Chemical group [H]C(*)=O 0.000 abstract 1
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
239000012442 inert solvent Substances 0.000 abstract 1
239000000543 intermediate Substances 0.000 abstract 1
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
125000003884 phenylalkyl group Chemical group 0.000 abstract 1
125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
125000001424 substituent group Chemical group 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
- C07D205/085—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a nitrogen atom directly attached in position 3
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Cephalosporin Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

IL83420A 1986-08-06 1987-08-03 Process for the preparation of stereospecific 4-halomethyl-azetidin-2-ones from beta-ypsilon-unsaturated o-acylhydroxamates IL83420A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US06/893,748 US4751296A (en)	1986-08-06	1986-08-06	Process for 4-halomethyl-azetidinones by cyclization of O-acylhydroxamates

Publications (2)

Publication Number	Publication Date
IL83420A0 IL83420A0 (en)	1988-01-31
IL83420A true IL83420A (en)	1992-07-15

Family

ID=25402018

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL83420A IL83420A (en)	1986-08-06	1987-08-03	Process for the preparation of stereospecific 4-halomethyl-azetidin-2-ones from beta-ypsilon-unsaturated o-acylhydroxamates

Country Status (9)

Country	Link
US (1)	US4751296A (de)
EP (1)	EP0256763B1 (de)
JP (1)	JPH0780839B2 (de)
KR (1)	KR880002824A (de)
AT (1)	ATE98229T1 (de)
CA (1)	CA1282066C (de)
DE (1)	DE3788384T2 (de)
HU (1)	HU201737B (de)
IL (1)	IL83420A (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE69217910T2 (de) *	1992-03-09	1997-09-04	Hoechst Ag	Vereinfachende Verfahren zur Herstellung von Vinylglycin (2-Aminobut-3-ensäure) und passende Auflösung von einem Derivat
CN100516052C (zh) *	2006-09-30	2009-07-22	中国科学院上海有机化学研究所	羟酰胺缩合酯类化合物、制备方法及其用途
US7807720B2 (en) *	2007-02-01	2010-10-05	Panthera Biopharma, Llc	Hydroxamic acid derivatives of 3-phenyl propionic acids useful as therapeutic agents for treating anthrax poisoning

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4174316A (en) *	1978-08-14	1979-11-13	Merck & Co., Inc.	4-Iodomethylazetidin-2-one
US4565654A (en) *	1983-03-28	1986-01-21	University Of Notre Dame Du Lac	N-Acyloxy monocyclic β-lactams

1986
- 1986-08-06 US US06/893,748 patent/US4751296A/en not_active Expired - Fee Related
1987
- 1987-08-03 IL IL83420A patent/IL83420A/xx not_active IP Right Cessation
- 1987-08-05 DE DE87306916T patent/DE3788384T2/de not_active Expired - Fee Related
- 1987-08-05 CA CA000543734A patent/CA1282066C/en not_active Expired - Lifetime
- 1987-08-05 AT AT87306916T patent/ATE98229T1/de not_active IP Right Cessation
- 1987-08-05 EP EP87306916A patent/EP0256763B1/de not_active Expired - Lifetime
- 1987-08-05 HU HU873580A patent/HU201737B/hu not_active IP Right Cessation
- 1987-08-05 JP JP62196152A patent/JPH0780839B2/ja not_active Expired - Lifetime
- 1987-08-05 KR KR1019870008577A patent/KR880002824A/ko not_active Ceased

Also Published As

Publication number	Publication date
JPH0780839B2 (ja)	1995-08-30
EP0256763A1 (de)	1988-02-24
DE3788384D1 (de)	1994-01-20
IL83420A0 (en)	1988-01-31
EP0256763B1 (de)	1993-12-08
KR880002824A (ko)	1988-05-11
DE3788384T2 (de)	1994-04-28
US4751296A (en)	1988-06-14
HU201737B (en)	1990-12-28
CA1282066C (en)	1991-03-26
HUT45011A (en)	1988-05-30
JPS6344560A (ja)	1988-02-25
ATE98229T1 (de)	1993-12-15

Legal Events

Date	Code	Title	Description
1998-08-16	RH	Patent void

Publication	Publication Date	Title
IL89929A0 (en)	1989-12-15	Beta-lactam derivatives,their preparation and pharmaceutical compositions containing them
AU3282793A (en)	1993-08-12	Improvements in or relating to organic compounds
ES2000604A6 (es)	1988-03-01	Un procedimiento para preparar aril-piperidin esteres
DE59408646D1 (de)	1999-09-30	Verfahren zur Herstellung von Biphenylderivaten
AU586867B2 (en)	1989-07-27	Biocidal mixture
AU4370089A (en)	1990-05-03	Preparation of 1,4-diazabicyclo(3.2.2.)nonane
IL83420A (en)	1992-07-15	Process for the preparation of stereospecific 4-halomethyl-azetidin-2-ones from beta-ypsilon-unsaturated o-acylhydroxamates
DK381488D0 (da)	1988-07-08	Fremgangsmaade til fremstilling af cephemforbindelser og cephalosporinderivater opnaaet ved fremgangsmaaden
NO902017L (no)	1990-11-09	Organisk kjemisk forbindelse, flytende krystallmateriale inneholdende denne og flytende krystallinnretning inneholdende dette.
AU1323188A (en)	1988-09-22	1,2-1,4 addition reaction sequence leading to diphenylacetylenes
AU1117892A (en)	1992-08-27	Process for the preparation of sulfonyl isocyanates
AU590455B2 (en)	1989-11-02	Process for preparing penems
ES8704447A1 (es)	1987-04-01	Un procedimiento para preparar el homero s de un 3-eter de 2-hidroxi -profil-amina.
DE3269494D1 (en)	1986-04-03	Novel intermediates and process for preparing (s)-3-acylamino-4-substituted-2-azetidinones
AU1370488A (en)	1988-09-29	A process for the preparation of nabumetone
ATE64381T1 (de)	1991-06-15	Verfahren zur herstellung von betalactamderivaten.
BR8804664A (pt)	1989-04-18	Processo para a preparacao de um composto e compostos