IL84261A - Pharmaceutical compositions comprising a 2,4-diphenyl 1,3-dioxane derivative and a thromboxane a2 synthetase inhibitor - Google Patents

Pharmaceutical compositions comprising a 2,4-diphenyl 1,3-dioxane derivative and a thromboxane a2 synthetase inhibitor

Info

Publication number: IL84261A
Authority: IL; Israel
Prior art keywords: thromboxane; diphenyl; pharmaceutical compositions; synthetase inhibitor; dioxane derivative
Prior art date: 1986-11-04

Application number

IL84261A

Other languages

English (en)

Original Assignee

Ici Plc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1986-11-04

Filing date

1987-10-23

Publication date

1991-12-15

1987-10-23 Application filed by Ici Plc filed Critical Ici Plc

1991-12-15 Publication of IL84261A publication Critical patent/IL84261A/xx

Links

239000008194 pharmaceutical composition Substances 0.000 title abstract 2
TUJMFENFEJTHDG-UHFFFAOYSA-N 2,4-diphenyl-1,3-dioxane Chemical class O1CCC(C=2C=CC=CC=2)OC1C1=CC=CC=C1 TUJMFENFEJTHDG-UHFFFAOYSA-N 0.000 title 1
108010069102 Thromboxane-A synthase Proteins 0.000 title 1
239000003112 inhibitor Substances 0.000 title 1
DSNBHJFQCNUKMA-SCKDECHMSA-N thromboxane A2 Chemical compound OC(=O)CCC\C=C/C[C@@H]1[C@@H](/C=C/[C@@H](O)CCCCC)O[C@@H]2O[C@H]1C2 DSNBHJFQCNUKMA-SCKDECHMSA-N 0.000 abstract 3
239000002253 acid Substances 0.000 abstract 1
230000015572 biosynthetic process Effects 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
201000010099 disease Diseases 0.000 abstract 1
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
229940079593 drug Drugs 0.000 abstract 1
239000003814 drug Substances 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1
229940127293 prostanoid Drugs 0.000 abstract 1
150000003814 prostanoids Chemical class 0.000 abstract 1
239000000126 substance Substances 0.000 abstract 1
238000003786 synthesis reaction Methods 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Epidemiology (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Hematology (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Pulmonology (AREA)
Diabetes (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

IL84261A 1986-11-04 1987-10-23 Pharmaceutical compositions comprising a 2,4-diphenyl 1,3-dioxane derivative and a thromboxane a2 synthetase inhibitor IL84261A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB868626297A GB8626297D0 (en)	1986-11-04	1986-11-04	Pharmaceutical compositions

Publications (1)

Publication Number	Publication Date
IL84261A true IL84261A (en)	1991-12-15

Family

ID=10606757

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL84261A IL84261A (en)	1986-11-04	1987-10-23	Pharmaceutical compositions comprising a 2,4-diphenyl 1,3-dioxane derivative and a thromboxane a2 synthetase inhibitor

Country Status (13)

Country	Link
US (1)	US4908380A (fr)
EP (1)	EP0266980B1 (fr)
JP (1)	JPS63130532A (fr)
AT (1)	ATE81774T1 (fr)
AU (1)	AU608546B2 (fr)
CA (1)	CA1308660C (fr)
DE (1)	DE3782396T2 (fr)
DK (1)	DK576887A (fr)
ES (1)	ES2052581T3 (fr)
GB (1)	GB8626297D0 (fr)
GR (1)	GR3006099T3 (fr)
IL (1)	IL84261A (fr)
ZA (1)	ZA877886B (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5248780A (en) *	1988-02-16	1993-09-28	Imperial Chemical Industries, Plc	Pyridyl substituted alkenoic acid derivatives
GB8901201D0 (en) *	1988-02-16	1989-03-15	Ici Plc	Pyridine derivatives
GB9021571D0 (en) *	1990-10-04	1990-11-21	Ici Plc	Heterocyclic acids
US20110178112A1 (en)	2006-01-18	2011-07-21	Evolva Sa	PPAR Modulators
EP2150111B1 (fr)	2007-01-18	2016-10-19	Evolva SA	1,3-dioxanes substitués utilisés en tant que modulateurs ppar
MX2009007667A (es) *	2007-01-18	2011-12-08	Evolva Sa	Profarmacos de 1,3-dioxanos sustituidos y sus usos.
AR072297A1 (es)	2008-06-27	2010-08-18	Novartis Ag	Derivados de indol-2-il-piridin-3-ilo, composicion farmaceutica que los comprende y su uso en medicamentos para el tratamiento de enfermedades mediadas por la sintasa aldosterona.

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB2111050B (en) *	1981-11-19	1985-09-11	Ciba Geigy Ag	N-substituted-2-pyridylindoles
GB8310407D0 (en) *	1982-05-12	1983-05-25	Ici Plc	1 3 - dioxan -5- ylalkenoic acids
GB8330120D0 (en) *	1983-11-11	1983-12-21	Ici Plc	Chemical process
GB8511890D0 (en) *	1985-05-10	1985-06-19	Ici Plc	Benzene derivatives
GB8619450D0 (en) *	1986-08-08	1986-09-17	Glaxo Group Ltd	Chemical compositions

1986
- 1986-11-04 GB GB868626297A patent/GB8626297D0/en active Pending
1987
- 1987-10-20 ZA ZA877886A patent/ZA877886B/xx unknown
- 1987-10-23 IL IL84261A patent/IL84261A/xx not_active IP Right Cessation
- 1987-10-30 ES ES87309635T patent/ES2052581T3/es not_active Expired - Lifetime
- 1987-10-30 DE DE8787309635T patent/DE3782396T2/de not_active Expired - Fee Related
- 1987-10-30 EP EP87309635A patent/EP0266980B1/fr not_active Expired - Lifetime
- 1987-10-30 AT AT87309635T patent/ATE81774T1/de not_active IP Right Cessation
- 1987-11-03 US US07/118,226 patent/US4908380A/en not_active Expired - Fee Related
- 1987-11-03 CA CA000550880A patent/CA1308660C/fr not_active Expired - Lifetime
- 1987-11-03 DK DK576887A patent/DK576887A/da not_active Application Discontinuation
- 1987-11-04 AU AU80698/87A patent/AU608546B2/en not_active Ceased
- 1987-11-04 JP JP62277555A patent/JPS63130532A/ja active Pending
1992
- 1992-10-29 GR GR910402232T patent/GR3006099T3/el unknown

Also Published As

Publication number	Publication date
CA1308660C (fr)	1992-10-13
DE3782396T2 (de)	1993-07-08
EP0266980A2 (fr)	1988-05-11
EP0266980B1 (fr)	1992-10-28
ZA877886B (en)	1988-05-04
DK576887D0 (da)	1987-11-03
ATE81774T1 (de)	1992-11-15
US4908380A (en)	1990-03-13
GB8626297D0 (en)	1986-12-03
GR3006099T3 (fr)	1993-06-21
ES2052581T3 (es)	1994-07-16
AU608546B2 (en)	1991-04-11
AU8069887A (en)	1988-05-05
DE3782396D1 (de)	1992-12-03
EP0266980A3 (en)	1989-11-08
DK576887A (da)	1988-05-05
JPS63130532A (ja)	1988-06-02

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Legal Events

Date	Code	Title	Description
2005-07-25	MM9K	Patent not in force due to non-payment of renewal fees