IL85627A - Pharmaceutical compositions for treatment of disorders of ischemic origin comprising metformin and its salts - Google Patents
Pharmaceutical compositions for treatment of disorders of ischemic origin comprising metformin and its saltsInfo
- Publication number
- IL85627A IL85627A IL85627A IL8562788A IL85627A IL 85627 A IL85627 A IL 85627A IL 85627 A IL85627 A IL 85627A IL 8562788 A IL8562788 A IL 8562788A IL 85627 A IL85627 A IL 85627A
- Authority
- IL
- Israel
- Prior art keywords
- metformin
- salts
- treatment
- disorders
- pharmaceutical compositions
- Prior art date
Links
- XZWYZXLIPXDOLR-UHFFFAOYSA-N metformin Chemical compound CN(C)C(=N)NC(N)=N XZWYZXLIPXDOLR-UHFFFAOYSA-N 0.000 title abstract 2
- 229960003105 metformin Drugs 0.000 title abstract 2
- 150000003839 salts Chemical class 0.000 title abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
- 208000035475 disorder Diseases 0.000 title 1
- 230000000302 ischemic effect Effects 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 239000003814 drug Substances 0.000 abstract 3
- 206010029113 Neovascularisation Diseases 0.000 abstract 1
- 230000000496 anti-anoxic effect Effects 0.000 abstract 1
- 230000002253 anti-ischaemic effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Epidemiology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
The invention relates to the use of metformin and its salts in the preparation of medicaments. This derivative is used in the preparation of medicaments manifesting anti-ischaemic and antianoxic properties. It is also employed in the preparation of medicaments intended for the treatment or regression of neovascularisation.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8703028A FR2611500B1 (en) | 1987-03-06 | 1987-03-06 | USE OF BIGUANIDE DERIVATIVES IN THE PREPARATION OF MEDICINES |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL85627A0 IL85627A0 (en) | 1988-08-31 |
| IL85627A true IL85627A (en) | 1993-01-14 |
Family
ID=9348653
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL85627A IL85627A (en) | 1987-03-06 | 1988-03-03 | Pharmaceutical compositions for treatment of disorders of ischemic origin comprising metformin and its salts |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP0283369B1 (en) |
| JP (1) | JPH0818978B2 (en) |
| AT (1) | ATE98120T1 (en) |
| AU (1) | AU610134B2 (en) |
| CA (1) | CA1328606C (en) |
| DE (1) | DE3886075T2 (en) |
| DK (1) | DK169713B1 (en) |
| FR (1) | FR2611500B1 (en) |
| IL (1) | IL85627A (en) |
| ZA (1) | ZA881540B (en) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5100919A (en) * | 1984-03-19 | 1992-03-31 | The Rockefeller University | Biguanides and derivatives thereof as inhibitors of advanced glycosylation of a target protein |
| WO1991012003A1 (en) * | 1990-02-09 | 1991-08-22 | The Upjohn Company | Use of insulin sensitizing agents to treat hypertension |
| US5356913A (en) * | 1990-02-09 | 1994-10-18 | The Upjohn Company | Use of insulin sensitizing agents to treat hypertension |
| DE4432757A1 (en) * | 1994-09-14 | 1996-03-21 | Boehringer Mannheim Gmbh | Pharmaceutical preparation containing metformin and process for its preparation |
| AU3631795A (en) * | 1994-09-15 | 1996-03-29 | Pharmagenesis, Inc. | Composition and method for immunotherapy |
| AU738804B2 (en) * | 1997-12-08 | 2001-09-27 | Bristol-Myers Squibb Company | Novel salts of metformin and method |
| US6099859A (en) | 1998-03-20 | 2000-08-08 | Andrx Pharmaceuticals, Inc. | Controlled release oral tablet having a unitary core |
| US6517870B1 (en) * | 1998-04-29 | 2003-02-11 | Sumitomo Pharmaceuticals Company, Limited | Oral formulation comprising biguanide and an organic acid |
| SI0976395T1 (en) * | 1998-07-30 | 2006-04-30 | Merck Sante Sas | Tablet for extended release of a drug in the stomach |
| US6099862A (en) * | 1998-08-31 | 2000-08-08 | Andrx Corporation | Oral dosage form for the controlled release of a biguanide and sulfonylurea |
| FR2796551B1 (en) * | 1999-07-23 | 2003-07-25 | Lipha | NOVEL METFORMIN SALTS, PROCESS FOR OBTAINING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME |
| FR2796940B1 (en) * | 1999-07-26 | 2005-04-08 | Lipha | NOVEL METFORMIN SALTS, PROCESS FOR OBTAINING THEM AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME |
| FR2809310B1 (en) * | 2000-05-26 | 2004-02-13 | Centre Nat Rech Scient | USE OF BIGUANIDE DERIVATIVES FOR MANUFACTURING A MEDICINAL PRODUCT HAVING A HEALING EFFECT |
| AU2001213150A1 (en) * | 2000-08-03 | 2002-02-18 | Olga Evgenievna Kolesova | Composition of metformin with succinic acid or salts thereof and method for treating diabetes |
| US7785627B2 (en) | 2002-09-20 | 2010-08-31 | Watson Pharmaceuticals, Inc. | Pharmaceutical formulation containing a biguanide and a thiazolidinedione derivative |
| US9060941B2 (en) | 2002-09-20 | 2015-06-23 | Actavis, Inc. | Pharmaceutical formulation containing a biguanide and a thiazolidinedione derivative |
| US7959946B2 (en) | 2002-09-20 | 2011-06-14 | Watson Pharmaceuticals, Inc. | Pharmaceutical formulation containing a biguanide and a thiazolidinedione derivative |
| US8084058B2 (en) | 2002-09-20 | 2011-12-27 | Watson Pharmaceuticals, Inc. | Pharmaceutical formulation containing a biguanide and a thiazolidinedione derivative |
| WO2007038979A1 (en) * | 2005-09-22 | 2007-04-12 | Swissco Development Ag | Effervescent metformin composition and tablets and granules made therefrom |
| CN105152983A (en) | 2007-01-29 | 2015-12-16 | 韩诺生物制药株式会社 | N, N-dimethyl imidodicarbonimidic diamide acetate, method for producing the same and pharmaceutical compositions comprising the same |
| GR1007299B (en) * | 2010-03-24 | 2011-06-06 | Uni - Pharma Κλεων Τσετης Φαρμακευτικα Εργαστηρια Αβεε Με Δ.Τ. Uni-Pharma Αβεε, | Original effervescent hydrochloric metformin composition in the form of tablets |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2448448A (en) * | 1942-06-08 | 1948-08-31 | Courtaulds Ltd | Dyeing of textile fibers containing nitrogen |
-
1987
- 1987-03-06 FR FR8703028A patent/FR2611500B1/en not_active Expired - Lifetime
-
1988
- 1988-03-02 AT AT88400484T patent/ATE98120T1/en not_active IP Right Cessation
- 1988-03-02 EP EP88400484A patent/EP0283369B1/en not_active Expired - Lifetime
- 1988-03-02 DE DE88400484T patent/DE3886075T2/en not_active Expired - Fee Related
- 1988-03-02 CA CA000560486A patent/CA1328606C/en not_active Expired - Fee Related
- 1988-03-03 IL IL85627A patent/IL85627A/en not_active IP Right Cessation
- 1988-03-03 ZA ZA881540A patent/ZA881540B/en unknown
- 1988-03-04 DK DK116788A patent/DK169713B1/en not_active IP Right Cessation
- 1988-03-04 AU AU12727/88A patent/AU610134B2/en not_active Ceased
- 1988-03-05 JP JP63050627A patent/JPH0818978B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| AU610134B2 (en) | 1991-05-16 |
| AU1272788A (en) | 1988-09-08 |
| IL85627A0 (en) | 1988-08-31 |
| DE3886075D1 (en) | 1994-01-20 |
| JPS63230628A (en) | 1988-09-27 |
| ATE98120T1 (en) | 1993-12-15 |
| EP0283369A3 (en) | 1989-11-29 |
| DK116788A (en) | 1988-09-07 |
| DK169713B1 (en) | 1995-01-23 |
| DE3886075T2 (en) | 1994-04-14 |
| ZA881540B (en) | 1988-08-26 |
| JPH0818978B2 (en) | 1996-02-28 |
| FR2611500A1 (en) | 1988-09-09 |
| CA1328606C (en) | 1994-04-19 |
| EP0283369B1 (en) | 1993-12-08 |
| DK116788D0 (en) | 1988-03-04 |
| FR2611500B1 (en) | 1990-05-04 |
| EP0283369A2 (en) | 1988-09-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| KB | Patent renewed | ||
| HP | Change in proprietorship | ||
| KB | Patent renewed | ||
| EXP | Patent expired |