IL86665A0 - Mitomycin analogs - Google Patents

Mitomycin analogs

Info

Publication number: IL86665A0
Authority: IL; Israel
Prior art keywords: analogs; mitomycin; mitomycin analogs; utility; mitosane
Prior art date: 1987-06-12

Application number

IL86665A

Other languages

English (en)

Original Assignee

Bristol Myers Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-06-12

Filing date

1988-06-09

Publication date

1988-11-30

1988-06-09 Application filed by Bristol Myers Co filed Critical Bristol Myers Co

1988-11-30 Publication of IL86665A0 publication Critical patent/IL86665A0/xx

Links

NWIBSHFKIJFRCO-WUDYKRTCSA-N Mytomycin Chemical class C1N2C(C(C(C)=C(N)C3=O)=O)=C3[C@@H](COC(N)=O)[C@@]2(OC)[C@@H]2[C@H]1N2 NWIBSHFKIJFRCO-WUDYKRTCSA-N 0.000 title abstract 5
NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
239000002246 antineoplastic agent Substances 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
229910052739 hydrogen Inorganic materials 0.000 abstract 1
239000001257 hydrogen Substances 0.000 abstract 1
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
229960004857 mitomycin Drugs 0.000 abstract 1
229910052717 sulfur Inorganic materials 0.000 abstract 1
239000011593 sulfur Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
- C07D487/14—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Hematology (AREA)
Oncology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Medicinal Preparation (AREA)

IL86665A 1987-06-12 1988-06-09 Mitomycin analogs IL86665A0 (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US6183987A	1987-06-12	1987-06-12

Publications (1)

Publication Number	Publication Date
IL86665A0 true IL86665A0 (en)	1988-11-30

Family

ID=22038465

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL86665A IL86665A0 (en)	1987-06-12	1988-06-09	Mitomycin analogs

Country Status (10)

Country	Link
US (1)	US5374739A (2)
EP (1)	EP0294828B1 (2)
JP (1)	JPS63316781A (2)
AT (1)	ATE93524T1 (2)
CA (1)	CA1326487C (2)
CY (1)	CY1742A (2)
DE (1)	DE3883434T2 (2)
ES (1)	ES2058182T3 (2)
HK (1)	HK127993A (2)
IL (1)	IL86665A0 (2)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6524812B1 (en)	1993-10-07	2003-02-25	Regents Of The University Of Minnesota	Genes encoding resistance to DNA alkylating agents
US6495348B1 (en) *	1993-10-07	2002-12-17	Regents Of The University Of Minnesota	Mitomycin biosynthetic gene cluster
CN1684641A (zh)	2002-09-26	2005-10-19	血管内装置有限公司	用于递送丝裂霉素通过洗脱生物相容可移植医疗器件的装置和方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NL129868C (2) *	1963-06-07
DE1570029A1 (de) *	1964-07-09	1970-04-09	Kyowa Hakko Kogyo Kk	Verfahren zur Herstellung von Mitosanverbindungen
US3420846A (en) *	1964-08-25	1969-01-07	Kyowa Hakko Kogyo Kk	7-substituted mitomycin a
US3332944A (en) *	1964-11-02	1967-07-25	American Cyanamid Co	Antibiotic derivatives of mitomycins a, b, c and porfiromycin
JPS5439098A (en) *	1977-08-31	1979-03-24	Kyowa Hakko Kogyo Co Ltd	Mitomycin c derivatives
US4460599A (en) *	1979-12-05	1984-07-17	University Patents, Inc.	Mitomycin analogs
US4268676A (en) *	1979-12-05	1981-05-19	University Patents, Inc.	Mitomycin analogs
US4487769A (en) *	1982-06-04	1984-12-11	Bristol-Myers Company	Amidines
US4579737A (en) *	1983-05-09	1986-04-01	Bristol-Myers Company	Bis-amidines
US4567256A (en) *	1983-05-09	1986-01-28	Bristol-Myers Company	Amidine process
AU581673B2 (en) *	1984-09-04	1989-03-02	Bristol-Myers Company	Substituted 7-oxomitosanes
FR2571373A1 (fr) *	1984-10-09	1986-04-11	Bristol Myers Co	Procede de preparation de derives n7-substitues de la mitomycine c

1988
- 1988-06-09 IL IL86665A patent/IL86665A0/xx unknown
- 1988-06-10 AT AT88109275T patent/ATE93524T1/de not_active IP Right Cessation
- 1988-06-10 DE DE88109275T patent/DE3883434T2/de not_active Expired - Fee Related
- 1988-06-10 EP EP88109275A patent/EP0294828B1/en not_active Expired - Lifetime
- 1988-06-10 CA CA000569183A patent/CA1326487C/en not_active Expired - Fee Related
- 1988-06-10 JP JP63143414A patent/JPS63316781A/ja active Granted
- 1988-06-10 ES ES88109275T patent/ES2058182T3/es not_active Expired - Lifetime
1993
- 1993-05-28 US US08/068,833 patent/US5374739A/en not_active Expired - Fee Related
- 1993-11-18 HK HK1279/93A patent/HK127993A/en not_active IP Right Cessation
1995
- 1995-10-20 CY CY174295A patent/CY1742A/xx unknown

Also Published As

Publication number	Publication date
JPH0563476B2 (2)	1993-09-10
JPS63316781A (ja)	1988-12-26
EP0294828A2 (en)	1988-12-14
CY1742A (en)	1995-10-20
EP0294828B1 (en)	1993-08-25
DE3883434D1 (de)	1993-09-30
DE3883434T2 (de)	1993-12-09
US5374739A (en)	1994-12-20
ES2058182T3 (es)	1994-11-01
CA1326487C (en)	1994-01-25
EP0294828A3 (en)	1990-05-09
HK127993A (en)	1993-11-26
ATE93524T1 (de)	1993-09-15

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