IL87221A - 7-(2-methyl- 4-aminopyrrolidinyl) naphthyridine or quinoline compounds and pharmaceutical compositions containing them - Google Patents

7-(2-methyl- 4-aminopyrrolidinyl) naphthyridine or quinoline compounds and pharmaceutical compositions containing them

Info

Publication number: IL87221A
Authority: IL; Israel
Prior art keywords: naphthyridine; aminopyrrolidinyl; methyl; pharmaceutical compositions; compositions containing
Prior art date: 1987-08-04

Application number

IL87221A

Other languages

English (en)

Other versions

IL87221A0 (en

Original Assignee

Abbott Lab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-08-04

Filing date

1988-07-26

Publication date

1993-02-21

1988-07-26 Application filed by Abbott Lab filed Critical Abbott Lab

1988-12-30 Publication of IL87221A0 publication Critical patent/IL87221A0/xx

1993-02-21 Publication of IL87221A publication Critical patent/IL87221A/xx

Links

125000002943 quinolinyl group Chemical class N1=C(C=CC2=CC=CC=C12)* 0.000 title abstract 2
KWYQZIJYJKBEPE-UHFFFAOYSA-N 5-methyl-1-(1,8-naphthyridin-2-yl)pyrrolidin-3-amine Chemical compound CC1CC(N)CN1C1=CC=C(C=CC=N2)C2=N1 KWYQZIJYJKBEPE-UHFFFAOYSA-N 0.000 title 1
239000008194 pharmaceutical composition Substances 0.000 title 1
FLBAYUMRQUHISI-UHFFFAOYSA-N 1,8-naphthyridine Chemical compound N1=CC=CC2=CC=CN=C21 FLBAYUMRQUHISI-UHFFFAOYSA-N 0.000 abstract 1
125000001255 4-fluorophenyl group Chemical group [H]C1=C([H])C(*)=C([H])C([H])=C1F 0.000 abstract 1
150000001412 amines Chemical class 0.000 abstract 1
230000000844 anti-bacterial effect Effects 0.000 abstract 1
125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
229910052739 hydrogen Inorganic materials 0.000 abstract 1
239000001257 hydrogen Substances 0.000 abstract 1
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Luminescent Compositions (AREA)

IL87221A 1987-08-04 1988-07-26 7-(2-methyl- 4-aminopyrrolidinyl) naphthyridine or quinoline compounds and pharmaceutical compositions containing them IL87221A (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US8141687A	1987-08-04	1987-08-04
US07/160,950 US4962112A (en)	1987-08-04	1988-02-26	7-(2-methyl-4-aminopyrrolidinyl)naphthryidine and quinoline compounds

Publications (2)

Publication Number	Publication Date
IL87221A0 IL87221A0 (en)	1988-12-30
IL87221A true IL87221A (en)	1993-02-21

Family

ID=26765562

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL87221A IL87221A (en)	1987-08-04	1988-07-26	7-(2-methyl- 4-aminopyrrolidinyl) naphthyridine or quinoline compounds and pharmaceutical compositions containing them

Country Status (14)

Country	Link
US (1)	US4962112A (fr)
EP (1)	EP0302371B1 (fr)
JP (1)	JP2645091B2 (fr)
KR (1)	KR970007918B1 (fr)
AT (1)	ATE115575T1 (fr)
AU (1)	AU615934B2 (fr)
CA (1)	CA1340784C (fr)
DE (1)	DE3852442T2 (fr)
DK (1)	DK169786B1 (fr)
ES (1)	ES2068190T3 (fr)
GR (1)	GR3015404T3 (fr)
IE (1)	IE65175B1 (fr)
IL (1)	IL87221A (fr)
NZ (1)	NZ225584A (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IL83049A (en) *	1986-07-04	1991-12-12	Chemie Linz Ag	4-quinolinone-3-carboxylic acid derivatives,their manufacture and pharmaceutical compositions containing them
US5173484A (en) *	1988-02-05	1992-12-22	Bayer Aktiengesellschaft	Quinolone- and naphthyridone carboxylic acid derivatives, process for their production, antibacterial compositions and feed additives containing them
IL91648A (en) *	1988-09-22	1997-03-18	Abbott Lab	Amino acid quinoline and naphthyridine derivatives, their preparation and pharmaceutical compositions containing them
CA2012681A1 (fr) *	1989-03-31	1990-09-30	Masayasu Okuhira	Derives de la quinolone, procedes de preparation et agents antibacteriens les renfermant
DE3918544A1 (de) *	1989-06-07	1990-12-13	Bayer Ag	Verfahren zur herstellung von 7-(3-amino- sowie 3-amino-methyl-1-pyrrolidinyl)-3-chinolon- carbonsaeuren sowie -naphthyridoncarbonsaeuren
US4992449A (en) *	1990-02-01	1991-02-12	American Cyanamid Company	7-(substituted)cycloalkylamino-1-(substituted)-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids
CN1054980A (zh) *	1990-02-19	1991-10-02	杏林制药株式会社	具有旋光活性的8-甲氧基喹诺酮羧酸衍生物，它们的制备方法以及它们的中间体

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4730000A (en) *	1984-04-09	1988-03-08	Abbott Laboratories	Quinoline antibacterial compounds
NZ208470A (en) *	1983-07-18	1988-06-30	Abbott Lab	6-fluoro-1,4-dihydro-4-oxo-quinoline-3-carboxylic acid derivatives and antibacterial compositions containing such
CS274601B2 (en) *	1983-07-27	1991-09-15	Dainippon Pharmaceutical Co	Method of 1,8-naphthyridine derivative production
US4616019A (en) *	1984-01-26	1986-10-07	Abbott Laboratories	Naphthyridine antibacterial compounds
JPS60228479A (ja) *	1984-04-26	1985-11-13	Toyama Chem Co Ltd	１，４−ジヒドロ−４−オキソナフチリジン誘導体およびその塩

1988
- 1988-02-26 US US07/160,950 patent/US4962112A/en not_active Expired - Lifetime
- 1988-07-21 IE IE223188A patent/IE65175B1/en not_active IP Right Cessation
- 1988-07-21 CA CA000572639A patent/CA1340784C/fr not_active Expired - Lifetime
- 1988-07-26 IL IL87221A patent/IL87221A/xx not_active IP Right Cessation
- 1988-07-27 EP EP88112103A patent/EP0302371B1/fr not_active Expired - Lifetime
- 1988-07-27 DE DE3852442T patent/DE3852442T2/de not_active Expired - Lifetime
- 1988-07-27 ES ES88112103T patent/ES2068190T3/es not_active Expired - Lifetime
- 1988-07-27 AT AT88112103T patent/ATE115575T1/de not_active IP Right Cessation
- 1988-07-27 NZ NZ225584A patent/NZ225584A/xx unknown
- 1988-08-02 KR KR1019880009842A patent/KR970007918B1/ko not_active Expired - Lifetime
- 1988-08-02 JP JP63193315A patent/JP2645091B2/ja not_active Expired - Lifetime
- 1988-08-03 AU AU20371/88A patent/AU615934B2/en not_active Expired
- 1988-08-04 DK DK435388A patent/DK169786B1/da not_active IP Right Cessation
1995
- 1995-03-13 GR GR950400557T patent/GR3015404T3/el unknown

Also Published As

Publication number	Publication date
DE3852442T2 (de)	1995-04-27
ES2068190T3 (es)	1995-04-16
EP0302371A2 (fr)	1989-02-08
EP0302371A3 (en)	1989-10-18
EP0302371B1 (fr)	1994-12-14
DK435388A (da)	1989-02-05
ATE115575T1 (de)	1994-12-15
DK435388D0 (da)	1988-08-04
JPS6450880A (en)	1989-02-27
KR890003755A (ko)	1989-04-17
IL87221A0 (en)	1988-12-30
AU2037188A (en)	1989-02-09
KR970007918B1 (ko)	1997-05-17
US4962112A (en)	1990-10-09
DE3852442D1 (de)	1995-01-26
DK169786B1 (da)	1995-02-27
JP2645091B2 (ja)	1997-08-25
GR3015404T3 (en)	1995-06-30
IE65175B1 (en)	1995-10-04
NZ225584A (en)	1990-06-26
AU615934B2 (en)	1991-10-17
IE882231L (en)	1989-02-04
CA1340784C (fr)	1999-10-12

Legal Events

Date	Code	Title
1998-12-27	KB	Patent renewed
2002-08-14	KB	Patent renewed
2006-09-05	KB	Patent renewed
2008-12-29	EXP	Patent expired

Publication	Publication Date	Title
IL72100A (en)	1988-09-30	6-fluoro-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid derivatives,their preparation and pharmaceutical compositions comprising them
GR3017850T3 (en)	1996-01-31	Pyrazolopyridine compound and processes for preparation thereof.
EP0342675A3 (en)	1990-12-27	Novel quinolonecarboxylic acid derivatives
IL93938A0 (en)	1990-12-23	Novel quinoline derivatives,preparation processes thereof,and antibacterial agents containing the same
EP0223385A3 (en)	1988-12-21	8-azabicycloû3,2,1¨octane and 9-azabicycloû3,3,1¨nonane derivatives
IL84917A0 (en)	1988-06-30	Quinolinone derivative,its preparation and pharmaceutical compositions containing it
ES8801290A1 (es)	1988-01-01	Un metodo para preparar derivados de cefem
HUT72434A (en)	1996-04-29	Novel pyridone carboxylic acid derivatives, pharmaceutical compositions containing them and processes for their production
IL87221A (en)	1993-02-21	7-(2-methyl- 4-aminopyrrolidinyl) naphthyridine or quinoline compounds and pharmaceutical compositions containing them
NZ222185A (en)	1990-07-26	N-substituted methanesulphonamide derivatives, and anticancer compositions containing such
ES8604959A1 (es)	1986-02-16	Un compuesto
NZ225659A (en)	1991-10-25	Pharmaceutical compositions containing pyrrolidin-1-yl-6-fluoro-1,4-dihydro-4-oxo-1,8 naphthyridine-3-carboxylic acid derivatives
GR3003126T3 (en)	1993-02-17	Quinolinecarboxylic acid derivatives, a composition comprising the same, process for preparing the same, and the use of the same for the manufacture of medicaments
HUT41773A (en)	1987-05-28	Process for producing 2-/ 4-substituted-amino-3-oxo-2-isoxazolidinyl-5-oxo-2-tetrahydrofurane-carboxylic acid derivatives and pharmaceutical compositions containing them
IL95619A0 (en)	1991-06-30	N-azabicyclo(3.3.0)octane amides of aromatic acids and pharmaceutical compositions containing them
NZ225763A (en)	1991-01-29	Pyrrolo (2,1-a) isoquinoline derivatives
DE3650023D1 (de)	1994-09-15	Beta-Lactamverbindungen und deren Herstellung.