IL89633A - 4,5,6,7-Tetrahydroimidazo [4,5,1-jk] [1,4]benzodiazepin-2-(1h)-ones, their preparation and pharmaceutical compositions containing them - Google Patents

4,5,6,7-Tetrahydroimidazo [4,5,1-jk] [1,4]benzodiazepin-2-(1h)-ones, their preparation and pharmaceutical compositions containing them

Info

Publication number: IL89633A
Authority: IL; Israel
Prior art keywords: formula; hydrogen; methyl; benzodiazepin; tetrahydro
Prior art date: 1988-03-18

Application number

IL8963389A

Other languages

English (en)

Other versions

IL89633A0 (en

Original Assignee

Janssen Pharmaceutica Nv

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1988-03-18

Filing date

1989-03-16

Publication date

1994-02-27

1989-03-16 Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv

1989-09-28 Publication of IL89633A0 publication Critical patent/IL89633A0/xx

1992-04-10 Priority to IL101562A priority Critical patent/IL101562A0/xx

1994-02-27 Publication of IL89633A publication Critical patent/IL89633A/en

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/06—Peri-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Virology (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Plural Heterocyclic Compounds (AREA)

IL8963389A 1988-03-18 1989-03-16 4,5,6,7-Tetrahydroimidazo [4,5,1-jk] [1,4]benzodiazepin-2-(1h)-ones, their preparation and pharmaceutical compositions containing them IL89633A (en)

Priority Applications (1)

Application Number	Priority Date	Filing Date	Title
IL101562A IL101562A0 (en)	1988-03-18	1992-04-10	Benzodiazepine derivatives

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB888806449A GB8806449D0 (en)	1988-03-18	1988-03-18	Antiviral hexahydroimiazo(1 4)benzodiazepin-2-ones

Publications (2)

Publication Number	Publication Date
IL89633A0 IL89633A0 (en)	1989-09-28
IL89633A true IL89633A (en)	1994-02-27

Family

ID=10633662

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL8963389A IL89633A (en)	1988-03-18	1989-03-16	4,5,6,7-Tetrahydroimidazo [4,5,1-jk] [1,4]benzodiazepin-2-(1h)-ones, their preparation and pharmaceutical compositions containing them

Country Status (26)

Country	Link
EP (1)	EP0336466B1 (de)
JP (1)	JP2693559B2 (de)
KR (1)	KR0133073B1 (de)
CN (1)	CN1031058C (de)
AT (1)	ATE84035T1 (de)
AU (2)	AU617435B2 (de)
BG (1)	BG51251A3 (de)
CA (1)	CA1310964C (de)
DE (1)	DE68904102T2 (de)
DK (1)	DK130989A (de)
ES (1)	ES2053946T3 (de)
FI (1)	FI89800C (de)
GB (1)	GB8806449D0 (de)
GR (1)	GR3006728T3 (de)
HU (2)	HU206873B (de)
IE (1)	IE63108B1 (de)
IL (1)	IL89633A (de)
JO (1)	JO1589B1 (de)
MY (1)	MY104942A (de)
NO (1)	NO167737C (de)
NZ (1)	NZ228216A (de)
PH (1)	PH27044A (de)
PT (1)	PT90034B (de)
SU (1)	SU1748647A3 (de)
TN (1)	TNSN89039A1 (de)
ZA (1)	ZA892062B (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5270464A (en) *	1989-03-14	1993-12-14	Janssen Pharmaceutica N.V.	Anti-HIV-1 tetrahydroimidazo[1,4]benzodiazepin-2-(thi) ones
IL93136A (en) *	1989-02-23	1995-01-24	Janssen Pharmaceutica Nv	Tetrahydroimidazo (1,4) benzodiazepin-2-thione derivatives, their preparation and pharmaceutical compositions containing them
NZ235137A (en) *	1989-09-13	1992-02-25	Janssen Pharmaceutica Nv	Tetrahydroimidazo(1,4)benzodiazepine derivatives, preparation and pharmaceutical compositions thereof
US5164376A (en) *	1989-10-30	1992-11-17	Hoffmann-Laroche Inc.	Method for treating retroviral infections with aryl-(2-pyrryl) keytone compound
EP0436245A1 (de) *	1989-12-27	1991-07-10	Duphar International Research B.V	Substituierte 3,4-annelierte Benzimidazol-2(1H)-one
US5141735A (en) *	1990-06-18	1992-08-25	Hoffman-La Roche, Inc.	Substituted amino-benzodiazepines having anitviral activity
NZ238664A (en) *	1990-07-06	1992-12-23	Janssen Pharmaceutica Nv	Substituted tetrahydroimidazo(1,4)benzodiazepin-2-(thi)ones and pharmaceutical anti-viral compositions
GB9018601D0 (en) *	1990-08-24	1990-10-10	Fujisawa Pharmaceutical Co	Tricyclic compounds
DE4036552C1 (de) *	1990-11-16	1992-02-06	Boehringer Mannheim Gmbh, 6800 Mannheim, De
GB9109557D0 (en)	1991-05-02	1991-06-26	Wellcome Found	Chemical compounds
DE69221309T2 (de) *	1991-10-11	1997-12-11	The Du Pont Merck Pharmaceutical Co., Wilmington, Del.	Cyclische harnstoffe und analoga verwendbar als retrovirale proteasehemmer
US6177435B1 (en)	1992-05-13	2001-01-23	Glaxo Wellcome Inc.	Therapeutic combinations
AU4079593A (en) *	1992-05-13	1993-12-13	Wellcome Foundation Limited, The	Therapeutic combinations
ATE551345T1 (de) *	2004-09-22	2012-04-15	Pfizer	Polymorphe formen des phosphatsalzes von 8-fluor- 2-ä4-ä(methylamino)methylüphenylü-1,3,4,5- tetrahydro-6h-azepinoä5,4,3-cdüindol-6-on
EP2079747B1 (de) *	2006-10-13	2011-03-09	Pfizer Limited	Als anabole mittel für vieh geeignete heterozyklische verbindungen
KR101589314B1 (ko)	2007-08-20	2016-01-28	에보텍 인터내셔널 게엠베하	수면 장애의 치료

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2534257A1 (fr) *	1982-10-12	1984-04-13	Roussel Uclaf	Nouveaux derives de la 6-amino 7-hydroxy 4,5,6,7-tetrahydro-imidazo/4,5,1-j-k/ /1/ benzazepin-2(1h)-one, leurs sels, application a titre de medicaments, compositions les renfermant et un intermediaire
IL93136A (en) *	1989-02-23	1995-01-24	Janssen Pharmaceutica Nv	Tetrahydroimidazo (1,4) benzodiazepin-2-thione derivatives, their preparation and pharmaceutical compositions containing them

1988
- 1988-03-18 GB GB888806449A patent/GB8806449D0/en active Pending
1989
- 1989-02-10 MY MYPI89000163A patent/MY104942A/en unknown
- 1989-03-03 NZ NZ228216A patent/NZ228216A/xx unknown
- 1989-03-08 AT AT89200575T patent/ATE84035T1/de not_active IP Right Cessation
- 1989-03-08 ES ES89200575T patent/ES2053946T3/es not_active Expired - Lifetime
- 1989-03-08 EP EP89200575A patent/EP0336466B1/de not_active Expired - Lifetime
- 1989-03-08 DE DE8989200575T patent/DE68904102T2/de not_active Expired - Fee Related
- 1989-03-13 JO JO19891589A patent/JO1589B1/en active
- 1989-03-14 AU AU31310/89A patent/AU617435B2/en not_active Ceased
- 1989-03-14 JP JP1059859A patent/JP2693559B2/ja not_active Expired - Lifetime
- 1989-03-16 IE IE85189A patent/IE63108B1/en not_active IP Right Cessation
- 1989-03-16 IL IL8963389A patent/IL89633A/en not_active IP Right Cessation
- 1989-03-16 BG BG087682A patent/BG51251A3/bg unknown
- 1989-03-16 HU HU911782A patent/HU206873B/hu not_active IP Right Cessation
- 1989-03-16 HU HU891240A patent/HU203757B/hu not_active IP Right Cessation
- 1989-03-16 CA CA000593935A patent/CA1310964C/en not_active Expired - Fee Related
- 1989-03-17 NO NO891176A patent/NO167737C/no unknown
- 1989-03-17 PH PH38339A patent/PH27044A/en unknown
- 1989-03-17 PT PT90034A patent/PT90034B/pt not_active IP Right Cessation
- 1989-03-17 FI FI891279A patent/FI89800C/fi not_active IP Right Cessation
- 1989-03-17 DK DK130989A patent/DK130989A/da not_active Application Discontinuation
- 1989-03-17 ZA ZA892062A patent/ZA892062B/xx unknown
- 1989-03-17 SU SU894613664A patent/SU1748647A3/ru active
- 1989-03-18 CN CN89101474A patent/CN1031058C/zh not_active Expired - Fee Related
- 1989-03-18 KR KR89003388A patent/KR0133073B1/ko not_active Expired - Fee Related
- 1989-03-19 TN TNTNSN89039A patent/TNSN89039A1/fr unknown
1991
- 1991-09-02 AU AU83602/91A patent/AU630575B2/en not_active Ceased
1992
- 1992-12-31 GR GR920403099T patent/GR3006728T3/el unknown

Also Published As

Publication number	Publication date
NO891176L (no)	1989-09-19
NZ228216A (en)	1991-01-29
GR3006728T3 (de)	1993-06-30
HU203757B (en)	1991-09-30
EP0336466A1 (de)	1989-10-11
IL89633A0 (en)	1989-09-28
BG51251A3 (bg)	1993-03-15
KR890014546A (ko)	1989-10-24
NO891176D0 (no)	1989-03-17
AU8360291A (en)	1991-11-07
CA1310964C (en)	1992-12-01
PT90034A (pt)	1989-11-10
GB8806449D0 (en)	1988-04-20
ES2053946T3 (es)	1994-08-01
HU206873B (en)	1993-01-28
DK130989D0 (da)	1989-03-17
FI89800B (fi)	1993-08-13
FI891279L (fi)	1989-09-19
PT90034B (pt)	1994-05-31
HU911782D0 (en)	1991-12-30
MY104942A (en)	1994-07-30
AU617435B2 (en)	1991-11-28
NO167737B (no)	1991-08-26
CN1036957A (zh)	1989-11-08
TNSN89039A1 (fr)	1991-02-04
KR0133073B1 (en)	1998-04-17
DE68904102D1 (de)	1993-02-11
FI89800C (fi)	1993-11-25
NO167737C (no)	1991-12-04
ATE84035T1 (de)	1993-01-15
IE890851L (en)	1989-09-18
HUT52099A (en)	1990-06-28
AU3131089A (en)	1989-09-21
ZA892062B (en)	1990-11-28
DE68904102T2 (de)	1993-05-06
JPH01275582A (ja)	1989-11-06
CN1031058C (zh)	1996-02-21
EP0336466B1 (de)	1992-12-30
AU630575B2 (en)	1992-10-29
JP2693559B2 (ja)	1997-12-24
IE63108B1 (en)	1995-03-22
SU1748647A3 (ru)	1992-07-15
FI891279A0 (fi)	1989-03-17
DK130989A (da)	1989-09-19
JO1589B1 (en)	1989-12-16
PH27044A (en)	1993-02-01

Legal Events

Date	Code	Title	Description
2000-02-17	RH	Patent void

Publication	Publication Date	Title
EP0336466B1 (de)	1992-12-30	Antivirale Tetrahydroimidazo(1,4)benzodiazepin-2-one
EP0384522B1 (de)	1993-01-13	Antivirale Tetrahydroimidazo[1,4]benzodiazepin-2-thione
US5371079A (en)	1994-12-06	Antiretroviral tetrahydroimidazo[1,4]benzodiazepin-2-(thi)ones
AU644192B2 (en)	1993-12-02	Antiviral tetrahydroimidazo(1,4)benzodiazepin-2-(thio)ones
AU635328B2 (en)	1993-03-18	Antiviral tetrahydroimidazo (1,4) benzodiazepines
HRP930480A2 (en)	1996-02-29	Antiviral tetrahydroimidazo (1,4) benzodiazepine-2-thiones