IL96812A0 - Iodinated non-ionic compounds,their preparation and contrast media containing them - Google Patents
Iodinated non-ionic compounds,their preparation and contrast media containing themInfo
- Publication number
- IL96812A0 IL96812A0 IL96812A IL9681290A IL96812A0 IL 96812 A0 IL96812 A0 IL 96812A0 IL 96812 A IL96812 A IL 96812A IL 9681290 A IL9681290 A IL 9681290A IL 96812 A0 IL96812 A0 IL 96812A0
- Authority
- IL
- Israel
- Prior art keywords
- preparation
- media containing
- contrast media
- ionic compounds
- iodinated non
- Prior art date
Links
- 229940039231 contrast media Drugs 0.000 title 1
- 239000002872 contrast media Substances 0.000 title 1
- 150000008040 ionic compounds Chemical class 0.000 title 1
- -1 2,3-dihydroxypropyl Chemical group 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 230000015572 biosynthetic process Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/04—X-ray contrast preparations
- A61K49/0433—X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/04—X-ray contrast preparations
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/28—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton
- C07C237/46—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having carbon atoms of carboxamide groups, amino groups and at least three atoms of bromine or iodine, bound to carbon atoms of the same non-condensed six-membered aromatic ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Cephalosporin Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Compounds having general formula (I), wherein R is selected among 2,3-dihydroxypropyl and 1,3-dihydroxy-2-propyl groups. These compounds can be used as contrasting products for X-ray image formation.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9000106A FR2656865B1 (en) | 1990-01-05 | 1990-01-05 | NON-IONIC IODINE COMPOUND, PROCESS FOR PREPARING THE SAME, AND CONTRAST PRODUCT CONTAINING THE SAME. |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL96812A0 true IL96812A0 (en) | 1991-09-16 |
| IL96812A IL96812A (en) | 1995-05-26 |
Family
ID=9392557
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL9681290A IL96812A (en) | 1990-01-05 | 1990-12-27 | Non-ionic (3-hydroxy-2-hydroxymethyl)-propionamido-2, 4, 6-triiodoisophtalamides their preparation and contrast media containing them |
Country Status (25)
| Country | Link |
|---|---|
| EP (1) | EP0437144B1 (en) |
| JP (1) | JP2529032B2 (en) |
| KR (1) | KR100194506B1 (en) |
| AT (1) | ATE114639T1 (en) |
| CA (1) | CA2050334C (en) |
| CZ (1) | CZ283986B6 (en) |
| DE (1) | DE69014581T2 (en) |
| DK (1) | DK0437144T3 (en) |
| ES (1) | ES2067710T3 (en) |
| FI (1) | FI102746B (en) |
| FR (1) | FR2656865B1 (en) |
| GR (1) | GR3015183T3 (en) |
| HK (1) | HK1006019A1 (en) |
| HU (1) | HUT59079A (en) |
| IE (1) | IE65329B1 (en) |
| IL (1) | IL96812A (en) |
| NO (1) | NO180297C (en) |
| NZ (1) | NZ236675A (en) |
| PL (1) | PL165683B1 (en) |
| PT (1) | PT96410B (en) |
| RO (1) | RO108559B1 (en) |
| SK (1) | SK279646B6 (en) |
| TR (1) | TR24944A (en) |
| WO (1) | WO1991009836A1 (en) |
| ZA (1) | ZA9173B (en) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2687669B1 (en) * | 1992-02-24 | 1997-12-19 | Guerbet Sa | COMPOUNDS FOR USE IN CONTRAST PRODUCTS FOR RADIOGRAPHY. |
| IT1256163B (en) * | 1992-10-27 | 1995-11-29 | Zambon Spa | PROCESS FOR THE PREPARATION OF AN INTERMEDIATE OF THE ORGANIC SYNTHESIS |
| IT1283319B1 (en) * | 1996-03-29 | 1998-04-16 | Zambon Spa | PROCESS FOR THE PREPARATION OF A USEFUL INTERMEDIATE IN THE SYNTHESIS OF HYDURATED CONTRAST MEDIA |
| PT108524B (en) | 2015-06-02 | 2017-12-15 | Hovione Farmaciência S A | PROCESS FOR THE PREPARATION OF USEFUL INTERMEDIARIES IN THE PREPARATION OF NON-IONIC CONTRACTING AGENTS |
| CN108947959B (en) * | 2017-05-27 | 2022-09-20 | 正大天晴药业集团股份有限公司 | Preparation method of non-ionic iodine contrast agent intermediate |
| CN110903275A (en) * | 2018-09-14 | 2020-03-24 | 苏州科伦药物研究有限公司 | Process for producing iobitridol, intermediate therefor, and process for producing the same |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2909439A1 (en) * | 1979-03-08 | 1980-09-18 | Schering Ag | NEW NON-ionic x-ray contrast agents |
| DE3429949A1 (en) * | 1984-08-10 | 1986-02-20 | Schering AG, 1000 Berlin und 4709 Bergkamen | Novel non-ionic 2,4,6-triiodoisophthalic acid bisamides, process for the preparation thereof and the use thereof as X-ray contrast media |
| IL90326A (en) * | 1988-06-02 | 1993-05-13 | Guerbet Sa | Non-ionic triiodobenzene compounds and contrast media containing them |
-
1990
- 1990-01-05 FR FR9000106A patent/FR2656865B1/en not_active Expired - Fee Related
- 1990-12-20 SK SK6482-90A patent/SK279646B6/en unknown
- 1990-12-20 CZ CS906482A patent/CZ283986B6/en not_active IP Right Cessation
- 1990-12-26 EP EP90403770A patent/EP0437144B1/en not_active Expired - Lifetime
- 1990-12-26 DE DE69014581T patent/DE69014581T2/en not_active Expired - Lifetime
- 1990-12-26 DK DK90403770.2T patent/DK0437144T3/en active
- 1990-12-26 ES ES90403770T patent/ES2067710T3/en not_active Expired - Lifetime
- 1990-12-26 AT AT90403770T patent/ATE114639T1/en not_active IP Right Cessation
- 1990-12-27 IL IL9681290A patent/IL96812A/en not_active IP Right Cessation
- 1990-12-28 HU HU912860A patent/HUT59079A/en unknown
- 1990-12-28 RO RO148263A patent/RO108559B1/en unknown
- 1990-12-28 WO PCT/FR1990/000969 patent/WO1991009836A1/en not_active Ceased
- 1990-12-28 KR KR1019910701024A patent/KR100194506B1/en not_active Expired - Lifetime
- 1990-12-28 CA CA002050334A patent/CA2050334C/en not_active Expired - Lifetime
-
1991
- 1991-01-03 PT PT96410A patent/PT96410B/en not_active IP Right Cessation
- 1991-01-04 JP JP3052354A patent/JP2529032B2/en not_active Expired - Lifetime
- 1991-01-04 IE IE3591A patent/IE65329B1/en not_active IP Right Cessation
- 1991-01-04 ZA ZA9173A patent/ZA9173B/en unknown
- 1991-01-04 NZ NZ236675A patent/NZ236675A/en unknown
- 1991-01-04 PL PL91288603A patent/PL165683B1/en not_active IP Right Cessation
- 1991-01-18 TR TR91/0009A patent/TR24944A/en unknown
- 1991-08-30 NO NO913403A patent/NO180297C/en not_active IP Right Cessation
- 1991-09-02 FI FI914114A patent/FI102746B/en active
-
1995
- 1995-02-27 GR GR940403887T patent/GR3015183T3/en unknown
-
1998
- 1998-06-10 HK HK98105100A patent/HK1006019A1/en not_active IP Right Cessation
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| KB | Patent renewed | ||
| KB | Patent renewed | ||
| KB | Patent renewed | ||
| MM9K | Patent not in force due to non-payment of renewal fees |