IL99579A - 2-(4-Piperidinyl)-1h-pyrido [4,3-d] indol-1-ones and related compounds and a process for their preparation - Google Patents

2-(4-Piperidinyl)-1h-pyrido [4,3-d] indol-1-ones and related compounds and a process for their preparation

Info

Publication number
IL99579A
IL99579A IL9957991A IL9957991A IL99579A IL 99579 A IL99579 A IL 99579A IL 9957991 A IL9957991 A IL 9957991A IL 9957991 A IL9957991 A IL 9957991A IL 99579 A IL99579 A IL 99579A
Authority
IL
Israel
Prior art keywords
compound
formula
pyrido
indol
ioweralkyl
Prior art date
Application number
IL9957991A
Other languages
English (en)
Other versions
IL99579A0 (en
Original Assignee
Hoechst Marion Roussel Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Marion Roussel Inc filed Critical Hoechst Marion Roussel Inc
Priority to IL113439A priority Critical patent/IL113439A/xx
Publication of IL99579A0 publication Critical patent/IL99579A0/xx
Publication of IL99579A publication Critical patent/IL99579A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychiatry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
IL9957991A 1990-09-27 1991-09-26 2-(4-Piperidinyl)-1h-pyrido [4,3-d] indol-1-ones and related compounds and a process for their preparation IL99579A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
IL113439A IL113439A (en) 1990-09-27 1991-09-26 2-(1-substituted-4-piperidinyl) aminoethyl-1h-indole-3- carboxylic acids, 2-(1-substituted- 4-piperidinyl) carbamoylmethyl-1h- indoles and their homologs

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07588870 US5102889B1 (en) 1990-09-27 1990-09-27 2-(4-piperidinyl)-1h-pyrido(4,3-b)indol-1-ones and related compounds

Publications (2)

Publication Number Publication Date
IL99579A0 IL99579A0 (en) 1992-08-18
IL99579A true IL99579A (en) 1999-04-11

Family

ID=24355647

Family Applications (3)

Application Number Title Priority Date Filing Date
IL9957991A IL99579A (en) 1990-09-27 1991-09-26 2-(4-Piperidinyl)-1h-pyrido [4,3-d] indol-1-ones and related compounds and a process for their preparation
IL113439A IL113439A (en) 1990-09-27 1991-09-26 2-(1-substituted-4-piperidinyl) aminoethyl-1h-indole-3- carboxylic acids, 2-(1-substituted- 4-piperidinyl) carbamoylmethyl-1h- indoles and their homologs
IL11343995A IL113439A0 (en) 1990-09-27 1995-04-20 Indole-piperidinyl compounds

Family Applications After (2)

Application Number Title Priority Date Filing Date
IL113439A IL113439A (en) 1990-09-27 1991-09-26 2-(1-substituted-4-piperidinyl) aminoethyl-1h-indole-3- carboxylic acids, 2-(1-substituted- 4-piperidinyl) carbamoylmethyl-1h- indoles and their homologs
IL11343995A IL113439A0 (en) 1990-09-27 1995-04-20 Indole-piperidinyl compounds

Country Status (22)

Country Link
US (1) US5102889B1 (cs)
EP (1) EP0481254B1 (cs)
JP (1) JP3241762B2 (cs)
KR (1) KR100210338B1 (cs)
AT (1) ATE132148T1 (cs)
AU (1) AU8475091A (cs)
CA (1) CA2052424C (cs)
CS (1) CS295191A3 (cs)
DE (1) DE69115833T2 (cs)
DK (1) DK0481254T3 (cs)
ES (1) ES2082078T3 (cs)
FI (1) FI914503A7 (cs)
GR (1) GR3018746T3 (cs)
HU (1) HUT59405A (cs)
IE (1) IE72156B1 (cs)
IL (3) IL99579A (cs)
NO (1) NO913777L (cs)
NZ (2) NZ239934A (cs)
PT (1) PT99074B (cs)
TW (1) TW199159B (cs)
YU (1) YU158691A (cs)
ZA (1) ZA917691B (cs)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4975445A (en) * 1989-12-06 1990-12-04 Warner-Lambert Company Substituted cyclohexenes as central nervous system agents
JP2004502642A (ja) * 2000-02-11 2004-01-29 ブリストル−マイヤーズ　スクイブ　カンパニー カンナビノイドレセプターモジュレーター、それらの製造方法、および呼吸系および非呼吸系疾患の処置のためのカンナビノイドレセプターモジュレーターの使用
KR102570307B1 (ko) * 2016-10-31 2023-08-25 주식회사 이엔에프테크놀로지 식각 조성물
CN109400617A (zh) * 2019-01-09 2019-03-01 湖北大学 一种新型吲哚并吡喃酮骨架化合物及其制备方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR205452A1 (es) * 1973-12-06 1976-05-07 Endo Lab Metodo para preparar nuevos trans-2, 3, 4, 4a, 5, 9b-hexahidro-5-fenil-1h-pirido(4,3-b) indoles
DE2557341A1 (de) * 1975-12-19 1977-06-30 Hoechst Ag Basisch substituierte indolderivate und verfahren zu ihrer herstellung
US4432978A (en) * 1979-07-30 1984-02-21 Pfizer Inc. Hexahydro-trans-pyridoindole
US4252811A (en) * 1979-07-30 1981-02-24 Pfizer Inc. Hexahydro-trans-pyridoindole neuroleptic agents
FR2619111B1 (fr) * 1987-08-07 1991-01-11 Synthelabo Derives de (piperidinyl-4)methyl-2 tetrahydro-1,2,3,4 9h-pyrido (3,4-b) indole, leur preparation et leur application en therapeutique
NZ226032A (en) * 1987-09-03 1991-12-23 Glaxo Group Ltd 2-(imidazolylmethyl)-pyrido or-azepino(4,3-b)indole-1(2h)-one derivatives; preparatory processes and pharmaceutical compositions
IL91167A (en) * 1988-08-02 1993-06-10 Glaxo Group Ltd Substituted 2-(imidazolymethyl)-pyrido- (and azepino-) indol-1-one derivatives, their preparation and pharmaceutical compositions containing them
GB8904551D0 (en) * 1989-02-28 1989-04-12 Glaxo Group Ltd Chemical compounds

Also Published As

Publication number Publication date
IL99579A0 (en) 1992-08-18
EP0481254A3 (en) 1992-05-06
NZ248705A (en) 1994-09-27
HU913081D0 (en) 1992-01-28
EP0481254B1 (en) 1995-12-27
ATE132148T1 (de) 1996-01-15
IL113439A (en) 1997-03-18
TW199159B (cs) 1993-02-01
DE69115833T2 (de) 1996-06-05
ZA917691B (en) 1992-05-27
NO913777L (no) 1992-03-30
JP3241762B2 (ja) 2001-12-25
DK0481254T3 (da) 1996-04-29
NZ239934A (en) 1994-09-27
IL113439A0 (en) 1995-07-31
NO913777D0 (no) 1991-09-26
PT99074B (pt) 1999-02-26
CA2052424A1 (en) 1992-03-28
KR100210338B1 (ko) 1999-07-15
CA2052424C (en) 2001-12-25
JPH04282381A (ja) 1992-10-07
IE913388A1 (en) 1992-04-08
KR920006355A (ko) 1992-04-27
FI914503L (fi) 1992-03-28
GR3018746T3 (en) 1996-04-30
FI914503A0 (fi) 1991-09-25
US5102889B1 (en) 1993-05-11
ES2082078T3 (es) 1996-03-16
HUT59405A (en) 1992-05-28
AU8475091A (en) 1992-04-02
FI914503A7 (fi) 1992-03-28
EP0481254A2 (en) 1992-04-22
US5102889A (en) 1992-04-07
CS295191A3 (en) 1992-04-15
DE69115833D1 (de) 1996-02-08
PT99074A (pt) 1992-08-31
YU158691A (sh) 1994-06-10
IE72156B1 (en) 1997-03-26

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Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees