IL99803A - Pharmaceutical compositions comprising interleukin-6 for the treatment of chronic lymphocytic leukemia and B-cell lymphomas - Google Patents

Pharmaceutical compositions comprising interleukin-6 for the treatment of chronic lymphocytic leukemia and B-cell lymphomas

Info

Publication number
IL99803A
IL99803A IL9980391A IL9980391A IL99803A IL 99803 A IL99803 A IL 99803A IL 9980391 A IL9980391 A IL 9980391A IL 9980391 A IL9980391 A IL 9980391A IL 99803 A IL99803 A IL 99803A
Authority
IL
Israel
Prior art keywords
treatment
lymphocytic leukemia
interleukin
chronic lymphocytic
pharmaceutical compositions
Prior art date
Application number
IL9980391A
Other languages
English (en)
Other versions
IL99803A0 (en
Original Assignee
Yeda Res & Dev
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yeda Res & Dev filed Critical Yeda Res & Dev
Priority to IL9980391A priority Critical patent/IL99803A/xx
Publication of IL99803A0 publication Critical patent/IL99803A0/xx
Priority to AU26365/92A priority patent/AU660493B2/en
Priority to CA002080504A priority patent/CA2080504C/en
Priority to ZA927965A priority patent/ZA927965B/xx
Priority to DK92117953T priority patent/DK0538810T3/da
Priority to AT92117953T priority patent/ATE164077T1/de
Priority to JP4323558A priority patent/JP2823453B2/ja
Priority to ES92117953T priority patent/ES2114903T3/es
Priority to EP92117953A priority patent/EP0538810B1/de
Priority to DE69224786T priority patent/DE69224786T2/de
Priority to US07/963,313 priority patent/US5462731A/en
Publication of IL99803A publication Critical patent/IL99803A/xx
Priority to GR980400613T priority patent/GR3026423T3/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
    • A61K38/1793—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/20—Interleukins [IL]
    • A61K38/204—IL-6
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cell Biology (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
IL9980391A 1991-10-20 1991-10-20 Pharmaceutical compositions comprising interleukin-6 for the treatment of chronic lymphocytic leukemia and B-cell lymphomas IL99803A (en)

Priority Applications (12)

Application Number Priority Date Filing Date Title
IL9980391A IL99803A (en) 1991-10-20 1991-10-20 Pharmaceutical compositions comprising interleukin-6 for the treatment of chronic lymphocytic leukemia and B-cell lymphomas
AU26365/92A AU660493B2 (en) 1991-10-20 1992-10-12 Method for treatment of chronic lymphocytic leukemia using interleukin -6
CA002080504A CA2080504C (en) 1991-10-20 1992-10-14 Pharmaceutical compositions comprising il-6
ZA927965A ZA927965B (en) 1991-10-20 1992-10-15 Pharmaceutical compositions comprising IL-6.
US07/963,313 US5462731A (en) 1991-10-20 1992-10-20 Use of IL-6 for the treatment of chronic lymphocyte leukemia (CLL) and B-cell lymphomas
DK92117953T DK0538810T3 (da) 1991-10-20 1992-10-20 Anvendelse af interleukin-6 til fremstilling af et farmaceutisk præparat til behandling af lymfocytisk leukæmi og B-celle-l
AT92117953T ATE164077T1 (de) 1991-10-20 1992-10-20 Die verwendung von interleukin-6 zur herstellung einer pharmazeutischen zusammensetzung zur behandlung von lymphocytic leukemia und b-zell lymphoma.
JP4323558A JP2823453B2 (ja) 1991-10-20 1992-10-20 インターロイキン−６の医薬組成物
ES92117953T ES2114903T3 (es) 1991-10-20 1992-10-20 Utilizacion de interleukina-6 para la fabricacion de una composicion farmaceutica para el tratamiento de la leucemia linfocitica y linfomas de las celulas b.
EP92117953A EP0538810B1 (de) 1991-10-20 1992-10-20 Die Verwendung von Interleukin-6 zur Herstellung einer pharmazeutischen Zusammensetzung zur Behandlung von Lymphocytic Leukemia und B-Zell Lymphoma.
DE69224786T DE69224786T2 (de) 1991-10-20 1992-10-20 Die Verwendung von Interleukin-6 zur Herstellung einer pharmazeutischen Zusammensetzung zur Behandlung von Lymphocytic Leukemia und B-Zell Lymphoma.
GR980400613T GR3026423T3 (en) 1991-10-20 1998-03-20 The use of IL-6 for the manufacture of a pharmaceutical composition for the treatment of lymphocytic leukemia and B-cell lymphomas.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IL9980391A IL99803A (en) 1991-10-20 1991-10-20 Pharmaceutical compositions comprising interleukin-6 for the treatment of chronic lymphocytic leukemia and B-cell lymphomas

Publications (2)

Publication Number Publication Date
IL99803A0 IL99803A0 (en) 1992-08-18
IL99803A true IL99803A (en) 1997-02-18

Family

ID=11062985

Family Applications (1)

Application Number Title Priority Date Filing Date
IL9980391A IL99803A (en) 1991-10-20 1991-10-20 Pharmaceutical compositions comprising interleukin-6 for the treatment of chronic lymphocytic leukemia and B-cell lymphomas

Country Status (12)

Country Link
US (1) US5462731A (de)
EP (1) EP0538810B1 (de)
JP (1) JP2823453B2 (de)
AT (1) ATE164077T1 (de)
AU (1) AU660493B2 (de)
CA (1) CA2080504C (de)
DE (1) DE69224786T2 (de)
DK (1) DK0538810T3 (de)
ES (1) ES2114903T3 (de)
GR (1) GR3026423T3 (de)
IL (1) IL99803A (de)
ZA (1) ZA927965B (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ263102A (en) * 1993-03-19 1997-05-26 Immunex Corp Pharmaceutical compositions comprising a ligand protein such as interleukin-4 and a soluble receptor protein that binds thereto
US5641657A (en) * 1994-05-19 1997-06-24 Human Genome Sciences, Inc. DNA encoding an interleukin-6 splice variant
US6028050A (en) * 1996-11-27 2000-02-22 Tosoh Corporation Method for increasing platelets by administering soluble interleukin-6 receptor
IL122818A0 (en) * 1997-07-10 1998-08-16 Yeda Res & Dev Chimeric interleukin-6 soluble receptor/ligand protein analogs thereof and uses thereof
AU9184901A (en) * 2000-09-14 2002-03-26 Ares Trading Sa Use of il-6r/il-6 chimera in huntington's disease
DE10107737A1 (de) * 2001-02-16 2002-09-05 S Rose John Christian Albrecht Verwendung eines Konjugats aus IL-6 und einem IL-6 Rezeptor zur Tumortherapie

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH04500208A (ja) * 1988-08-26 1992-01-16 シェリング・コーポレーション インターロイキン―６で末端分化を誘導することによる骨髄性白血病の治療
PT92479A (pt) * 1988-12-01 1990-06-29 Univ North Carolina Processo de preparacao de genes recombinantes e suas proteinas de codificacao
JP2805224B2 (ja) * 1989-01-13 1998-09-30 味の素株式会社 血小板減少症治療剤
US5087448A (en) * 1989-02-02 1992-02-11 The Board Of Regents Of The University Of Oklahoma Enhancing growth of megakaryocytes in mammals using interleuking 6
US5216128A (en) * 1989-06-01 1993-06-01 Yeda Research And Development Co., Ltd. IFN-β2/IL-6 receptor its preparation and pharmaceutical compositions containing it

Also Published As

Publication number Publication date
CA2080504C (en) 2006-10-03
GR3026423T3 (en) 1998-06-30
AU660493B2 (en) 1995-06-29
DE69224786D1 (de) 1998-04-23
JP2823453B2 (ja) 1998-11-11
EP0538810A2 (de) 1993-04-28
EP0538810B1 (de) 1998-03-18
IL99803A0 (en) 1992-08-18
ATE164077T1 (de) 1998-04-15
ZA927965B (en) 1993-05-04
US5462731A (en) 1995-10-31
JPH0725785A (ja) 1995-01-27
DE69224786T2 (de) 1998-07-09
EP0538810A3 (en) 1993-08-04
AU2636592A (en) 1993-04-22
CA2080504A1 (en) 1993-04-21
ES2114903T3 (es) 1998-06-16
DK0538810T3 (da) 1998-12-21

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