IN2009KN04279A - - Google Patents

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Info

Publication number: IN2009KN04279A
Authority: IN; India
Prior art keywords: alkyl group; group; hydrogen atom; nrr; represent
Prior art date: 2007-06-13

Application number

Other languages

English (en)

Inventor

Antoine Alam

Francoise Bono

Olivier Duclos

Cort Gary Mc

Original Assignee

Sanofi Aventis

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2007-06-13

Filing date

2008-06-11

Publication date

2015-08-28

2008-06-11 Application filed by Sanofi Aventis filed Critical Sanofi Aventis

2015-08-28 Publication of IN2009KN04279A publication Critical patent/IN2009KN04279A/en

Links

125000000217 alkyl group Chemical group 0.000 abstract 4
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 3
125000003545 alkoxy group Chemical group 0.000 abstract 2
150000001875 compounds Chemical class 0.000 abstract 1
239000003814 drug Substances 0.000 abstract 1
238000002360 preparation method Methods 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Urology & Nephrology (AREA)
Ophthalmology & Optometry (AREA)
Immunology (AREA)
Rheumatology (AREA)
Physical Education & Sports Medicine (AREA)
Orthopedic Medicine & Surgery (AREA)
Dermatology (AREA)
Oncology (AREA)
Gastroenterology & Hepatology (AREA)
Pain & Pain Management (AREA)
Communicable Diseases (AREA)
Vascular Medicine (AREA)
Neurology (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Epidemiology (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Quinoline Compounds (AREA)

IN4279KON2009 2007-06-13 2008-06-11 IN2009KN04279A (pt)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
FR0704193A FR2917413B1 (fr)	2007-06-13	2007-06-13	Derives de 7-alkynyl-1,8-naphthyridones, leur preparation et leur application en therapeutique
PCT/FR2008/000794 WO2009007536A2 (fr)	2007-06-13	2008-06-11	Dérivés de 7 -alkynyl-1,8-naphthyridones, leur préparation et leur application en thérapeutique

Publications (1)

Publication Number	Publication Date
IN2009KN04279A true IN2009KN04279A (pt)	2015-08-28

Family

ID=38961501

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IN4279KON2009 IN2009KN04279A (pt)	2007-06-13	2008-06-11

Country Status (28)

Country	Link
US (2)	US8263614B2 (pt)
EP (1)	EP2158194B1 (pt)
JP (1)	JP5346337B2 (pt)
KR (1)	KR20100019507A (pt)
CN (1)	CN101815715B (pt)
AR (1)	AR066955A1 (pt)
AT (1)	ATE509923T1 (pt)
AU (1)	AU2008274100B2 (pt)
BR (1)	BRPI0813809B1 (pt)
CA (1)	CA2690349C (pt)
CO (1)	CO6150157A2 (pt)
CY (1)	CY1111748T1 (pt)
DK (1)	DK2158194T3 (pt)
EA (1)	EA016552B1 (pt)
ES (1)	ES2366629T3 (pt)
FR (1)	FR2917413B1 (pt)
HR (1)	HRP20110550T1 (pt)
IL (1)	IL202677A (pt)
IN (1)	IN2009KN04279A (pt)
MA (1)	MA31674B1 (pt)
ME (1)	ME00957B (pt)
MX (1)	MX2009013514A (pt)
MY (1)	MY146939A (pt)
NZ (1)	NZ581883A (pt)
PL (1)	PL2158194T3 (pt)
PT (1)	PT2158194E (pt)
SI (1)	SI2158194T1 (pt)
WO (1)	WO2009007536A2 (pt)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2917412B1 (fr) *	2007-06-13	2009-08-21	Sanofi Aventis Sa	Derives de 7-alkynyl, 1,8-naphthyridones, leur preparation et leur application en therapeutique
EP2249831A2 (en)	2007-12-10	2010-11-17	Sunesis Pharmaceuticals, Inc.	Methods of using (+)-1,4-dihydro-7-ý(3s,4s)-3-methoxy-4-(methylamino)-1-pyrrolidinyl¨-4-oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic acid for treatment of antecedent hematologic disorders
FR2933700B1 (fr)	2008-07-08	2010-07-30	Sanofi Aventis	Derives de pyridino-pyridinones, leur preparation et leur application en therapeutique
FR2952934B1 (fr) *	2009-11-23	2012-06-22	Sanofi Aventis	Derives de pyridino-pyridinones, leur preparation et leur application en therapeutique
FR2954943B1 (fr) *	2010-01-07	2013-03-01	Sanofi Aventis	Derives de pyridino-pyridinones arylsulfonamides, leur preparation et leur application en therapeutique
FR2955109B1 (fr) *	2010-01-08	2012-09-07	Sanofi Aventis	Derives de 5-oxo-5,8-dihydro-pyrido[2, 3-d]pyrimidine, leur preparation et leur application en therapeutique
WO2012009097A1 (en) *	2010-06-17	2012-01-19	Cytokinetics, Inc.	Methods of treating lung disease
WO2013072882A1 (en) *	2011-11-18	2013-05-23	Actelion Pharmaceuticals Ltd	2 -amino- 1, 8 -naphthyridine-3 -carboxamide derivatives as antimicrobial agents
CN116509854B (zh) *	2023-04-26	2025-05-23	浙江省中医院、浙江中医药大学附属第一医院（浙江省东方医院）	一种萘啶酮衍生物的应用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ES2211965T3 (es)	1995-08-02	2004-07-16	Darwin Discovery Limited	Quinolonas y su utilizacion terapeutica.
KR20010005830A (ko)	1998-01-29	2001-01-15	도리이 신이치로	타입 ⅳ 포스포디에스테라제 억제활성을 지닌 1-사이클로알킬-1,8-나프틸리딘-4-온 유도체
DE19826050A1 (de) *	1998-06-12	1999-12-16	Bayer Ag	Verfahren zur Herstellung von Chinolon- und Naphthyridoncarbonsäuren und deren Ester
IL158783A0 (en)	2001-05-08	2004-05-12	Schering Ag	Selective anthranilamide pyridine amides as inhibitors of vegfr-2 and vegfr-3
EP1397359B1 (en)	2001-05-24	2005-08-31	Merck Frosst Canada & Co.	1-biaryl-1,8-napthyridin-4-one phosphodiesterase-4 inhibitors
US7148357B2 (en)	2002-07-31	2006-12-12	Schering Ag	VEGFR-2 and VEGFR-3 inhibitory anthranilamide pyridines
WO2005118587A1 (en) *	2004-06-02	2005-12-15	Takeda Pharmaceutical Company Limited	Indole derivative and use for treatment of cancer
FR2917412B1 (fr) *	2007-06-13	2009-08-21	Sanofi Aventis Sa	Derives de 7-alkynyl, 1,8-naphthyridones, leur preparation et leur application en therapeutique

2007
- 2007-06-13 FR FR0704193A patent/FR2917413B1/fr not_active Expired - Fee Related
2008
- 2008-06-11 HR HR20110550T patent/HRP20110550T1/hr unknown
- 2008-06-11 AT AT08826271T patent/ATE509923T1/de active
- 2008-06-11 MY MYPI20095317A patent/MY146939A/en unknown
- 2008-06-11 EA EA201070010A patent/EA016552B1/ru not_active IP Right Cessation
- 2008-06-11 PT PT08826271T patent/PT2158194E/pt unknown
- 2008-06-11 IN IN4279KON2009 patent/IN2009KN04279A/en unknown
- 2008-06-11 EP EP08826271A patent/EP2158194B1/fr active Active
- 2008-06-11 CA CA2690349A patent/CA2690349C/fr active Active
- 2008-06-11 NZ NZ581883A patent/NZ581883A/en not_active IP Right Cessation
- 2008-06-11 KR KR1020097025902A patent/KR20100019507A/ko not_active Abandoned
- 2008-06-11 CN CN200880020155.4A patent/CN101815715B/zh active Active
- 2008-06-11 AR ARP080102478A patent/AR066955A1/es unknown
- 2008-06-11 PL PL08826271T patent/PL2158194T3/pl unknown
- 2008-06-11 WO PCT/FR2008/000794 patent/WO2009007536A2/fr not_active Ceased
- 2008-06-11 MX MX2009013514A patent/MX2009013514A/es active IP Right Grant
- 2008-06-11 BR BRPI0813809-5A patent/BRPI0813809B1/pt active IP Right Grant
- 2008-06-11 ES ES08826271T patent/ES2366629T3/es active Active
- 2008-06-11 JP JP2010511681A patent/JP5346337B2/ja active Active
- 2008-06-11 AU AU2008274100A patent/AU2008274100B2/en active Active
- 2008-06-11 SI SI200830319T patent/SI2158194T1/sl unknown
- 2008-06-11 ME MEP-2009-334A patent/ME00957B/me unknown
- 2008-06-11 DK DK08826271.2T patent/DK2158194T3/da active
2009
- 2009-12-04 US US12/631,130 patent/US8263614B2/en active Active
- 2009-12-10 IL IL202677A patent/IL202677A/en not_active IP Right Cessation
- 2009-12-11 CO CO09142107A patent/CO6150157A2/es unknown
2010
- 2010-01-12 MA MA32509A patent/MA31674B1/fr unknown
2011
- 2011-08-09 CY CY20111100763T patent/CY1111748T1/el unknown
2012
- 2012-06-01 US US13/486,414 patent/US8586602B2/en active Active

Also Published As

Publication number	Publication date
CO6150157A2 (es)	2010-04-20
CN101815715A (zh)	2010-08-25
DK2158194T3 (da)	2011-09-12
MY146939A (en)	2012-10-15
WO2009007536A8 (fr)	2010-01-07
JP2010529179A (ja)	2010-08-26
EA016552B1 (ru)	2012-05-30
CA2690349A1 (fr)	2009-01-15
CN101815715B (zh)	2014-10-08
CY1111748T1 (el)	2015-10-07
CA2690349C (fr)	2015-11-24
US20120238598A1 (en)	2012-09-20
SI2158194T1 (sl)	2011-10-28
ATE509923T1 (de)	2011-06-15
FR2917413A1 (fr)	2008-12-19
JP5346337B2 (ja)	2013-11-20
FR2917413B1 (fr)	2009-08-21
WO2009007536A2 (fr)	2009-01-15
MA31674B1 (fr)	2010-09-01
HK1143590A1 (en)	2011-01-07
US8586602B2 (en)	2013-11-19
NZ581883A (en)	2011-05-27
US8263614B2 (en)	2012-09-11
ES2366629T3 (es)	2011-10-24
HRP20110550T1 (hr)	2011-09-30
AU2008274100A1 (en)	2009-01-15
EP2158194B1 (fr)	2011-05-18
WO2009007536A3 (fr)	2009-03-19
PT2158194E (pt)	2011-08-17
ME00957B (me)	2012-06-20
EP2158194A2 (fr)	2010-03-03
MX2009013514A (es)	2010-01-27
KR20100019507A (ko)	2010-02-18
IL202677A (en)	2014-12-31
EA201070010A1 (ru)	2010-06-30
BRPI0813809A2 (pt)	2020-02-04
PL2158194T3 (pl)	2011-10-31
US20100144782A1 (en)	2010-06-10
AR066955A1 (es)	2009-09-23
IL202677A0 (en)	2010-06-30
BRPI0813809B1 (pt)	2021-05-25
AU2008274100B2 (en)	2013-07-11

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TW200700419A (en)	2007-01-01	5,6-dialkyl-7-aminoazolopyrimidines, their preparation and their use for controlling harmful fungi, and compositions comprising these compounds
EA200700179A1 (ru)	2007-08-31	Производные пиррола, их получение и их применение в терапии
MX2010007348A (es)	2010-08-18	Derivados de n-fenil-imidazo[1,2-a]piridin-2-carboxamidas, su preparacion y su aplicacion terapeutica.