IN2012DN00338A - - Google Patents

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Publication number
IN2012DN00338A
IN2012DN00338A IN338DEN2012A IN2012DN00338A IN 2012DN00338 A IN2012DN00338 A IN 2012DN00338A IN 338DEN2012 A IN338DEN2012 A IN 338DEN2012A IN 2012DN00338 A IN2012DN00338 A IN 2012DN00338A
Authority
IN
India
Prior art keywords
methods
relates
present
region containing
containing protein
Prior art date
Application number
Inventor
Soice Neil
Hubbard Dana
Zhang Yu
Harmzik James
Original Assignee
Millipore Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Millipore Corp filed Critical Millipore Corp
Publication of IN2012DN00338A publication Critical patent/IN2012DN00338A/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/22—Affinity chromatography or related techniques based upon selective absorption processes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/36—Extraction; Separation; Purification by a combination of two or more processes of different types
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/18—Ion-exchange chromatography
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)

Abstract

The present invention relates, at least in part, to improved methods of protein purification. In particular, the present invention relates, at least in part, to methods for purifying an Fc region containing protein from a composition comprising the Fc region containing protein and one or more impurities, where the methods eliminate the need for a holding tank and/or a buffer exchange step.
IN338DEN2012 2009-08-07 2010-08-05 IN2012DN00338A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US27370909P 2009-08-07 2009-08-07
PCT/US2010/044539 WO2011017514A1 (en) 2009-08-07 2010-08-05 Methods for purifying a target protein from one or more impurities in a sample

Publications (1)

Publication Number Publication Date
IN2012DN00338A true IN2012DN00338A (en) 2015-05-22

Family

ID=43544660

Family Applications (1)

Application Number Title Priority Date Filing Date
IN338DEN2012 IN2012DN00338A (en) 2009-08-07 2010-08-05

Country Status (9)

Country Link
US (1) US8536316B2 (en)
EP (1) EP2462157B1 (en)
JP (2) JP5791602B2 (en)
KR (1) KR101415660B1 (en)
CN (2) CN102574911B (en)
ES (1) ES2817802T3 (en)
IN (1) IN2012DN00338A (en)
SG (1) SG177577A1 (en)
WO (1) WO2011017514A1 (en)

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KR20140091721A (en) * 2011-11-02 2014-07-22 제넨테크, 인크. Overload and elute chromatography
WO2013075740A1 (en) 2011-11-23 2013-05-30 Sanofi Antibody purification method
CN102492040B (en) * 2011-12-29 2014-06-25 嘉和生物药业有限公司 Method for purifying anti-HER2 or/and anti-HER3 antibody proteins
SG10201701224UA (en) * 2012-03-12 2017-04-27 Merck Patent Gmbh Removal of protein aggregates from biopharmaceutical preparations in a flowthrough mode
EP2682168A1 (en) 2012-07-02 2014-01-08 Millipore Corporation Purification of biological molecules
EP2889617B1 (en) 2012-08-27 2017-10-11 Asahi Kasei Medical Co., Ltd. Antibody purification method by means of temperature-responsive chromatography
KR102250937B1 (en) * 2012-09-11 2021-05-12 코히러스 바이오사이언시즈, 인코포레이티드 Correctly folded etanercept in high purity and excellent yield
MY178616A (en) 2012-09-17 2020-10-19 Grace W R & Co Chromatography media and devices
US10421795B2 (en) 2012-12-17 2019-09-24 Merck Sharp & Dohme Corp. Process for purifying insulin and analogues thereof
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DK2994485T3 (en) * 2013-05-06 2018-04-23 Sanofi Sa CONTINUOUS MULTIPLE STEP PROCEDURE FOR PURIFICATION OF ANTIBODIES
EP3041593B1 (en) * 2013-09-05 2025-01-29 F. Hoffmann-La Roche AG Method of cleaning a chromatography material for its reuse
KR20160054597A (en) * 2013-09-17 2016-05-16 가부시키가이샤 가네카 Novel antibody purification method and antibody obtained therefrom, and novel antibody purification method using cation exchanger and antibody obtained therefrom
US9951101B2 (en) 2013-12-12 2018-04-24 Emd Millipore Corporation Protein separations using an acrylamide containing filter
JP6612242B2 (en) * 2014-02-14 2019-11-27 ジーイー・ヘルスケア・バイオサイエンス・アクチボラグ Automated multi-stage purification system and multi-stage chromatography purification method
EP3116891B1 (en) 2014-03-10 2020-02-12 Richter Gedeon Nyrt. Immunoglobulin purification using pre-cleaning steps
CN104826617B (en) * 2014-03-25 2017-06-13 西北大学 Difunctional mixed mode chromatographic stationary phases of a kind of WAX/HIC for Separation of Proteins and preparation method thereof
JP6914189B2 (en) 2014-05-02 2021-08-04 ダブリュー・アール・グレース・アンド・カンパニー−コーンＷ Ｒ Ｇｒａｃｅ ＆ Ｃｏ−Ｃｏｎｎ Functionalized Carrier Materials and Methods for Making and Using Functionalized Carrier Materials
WO2015198320A1 (en) * 2014-06-24 2015-12-30 Insight Biopharmaceuticals Ltd. Methods of purifying antibodies
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CN107921407B (en) 2015-06-05 2022-07-05 格雷斯公司 Biological treatment adsorption clarifying agent and preparation and use methods thereof
WO2017176735A1 (en) * 2016-04-05 2017-10-12 Haemonetics Corporation Methods and devices for the enrichment of immunoglobulin from blood
CN107964044B (en) * 2016-10-19 2021-11-19 无锡科捷诺生物科技有限责任公司 Method for purifying anti-CD 20 monoclonal antibody from milk sample
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EP3546475A1 (en) 2018-03-27 2019-10-02 Sanofi Full flow-through process for purifying recombinant proteins
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TW202128264A (en) 2019-09-25 2021-08-01 瑞士商赫孚孟拉羅股份公司 Cation chromatography using predicted elution buffer salt concentration
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Also Published As

Publication number Publication date
EP2462157A4 (en) 2012-12-26
US20110065901A1 (en) 2011-03-17
KR101415660B1 (en) 2014-07-16
EP2462157A1 (en) 2012-06-13
EP2462157B1 (en) 2020-06-17
WO2011017514A1 (en) 2011-02-10
JP5791602B2 (en) 2015-10-07
ES2817802T3 (en) 2021-04-08
CN102574911A (en) 2012-07-11
US8536316B2 (en) 2013-09-17
JP2013501721A (en) 2013-01-17
SG177577A1 (en) 2012-03-29
KR20120089432A (en) 2012-08-10
JP6335838B2 (en) 2018-05-30
CN107188960A (en) 2017-09-22
JP2015157846A (en) 2015-09-03
CN102574911B (en) 2017-06-06

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