IN2012DN00338A - - Google Patents

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Publication number
IN2012DN00338A
IN2012DN00338A IN338DEN2012A IN2012DN00338A IN 2012DN00338 A IN2012DN00338 A IN 2012DN00338A IN 338DEN2012 A IN338DEN2012 A IN 338DEN2012A IN 2012DN00338 A IN2012DN00338 A IN 2012DN00338A
Authority
IN
India
Prior art keywords
methods
relates
present
region containing
containing protein
Prior art date
Application number
Inventor
Soice Neil
Hubbard Dana
Zhang Yu
Harmzik James
Original Assignee
Millipore Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Millipore Corp filed Critical Millipore Corp
Publication of IN2012DN00338A publication Critical patent/IN2012DN00338A/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/22—Affinity chromatography or related techniques based upon selective absorption processes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/36—Extraction; Separation; Purification by a combination of two or more processes of different types
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/18—Ion-exchange chromatography
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)

Abstract

The present invention relates, at least in part, to improved methods of protein purification. In particular, the present invention relates, at least in part, to methods for purifying an Fc region containing protein from a composition comprising the Fc region containing protein and one or more impurities, where the methods eliminate the need for a holding tank and/or a buffer exchange step.
IN338DEN2012 2009-08-07 2010-08-05 IN2012DN00338A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US27370909P 2009-08-07 2009-08-07
PCT/US2010/044539 WO2011017514A1 (en) 2009-08-07 2010-08-05 Methods for purifying a target protein from one or more impurities in a sample

Publications (1)

Publication Number Publication Date
IN2012DN00338A true IN2012DN00338A (en) 2015-05-22

Family

ID=43544660

Family Applications (1)

Application Number Title Priority Date Filing Date
IN338DEN2012 IN2012DN00338A (en) 2009-08-07 2010-08-05

Country Status (9)

Country Link
US (1) US8536316B2 (en)
EP (1) EP2462157B1 (en)
JP (2) JP5791602B2 (en)
KR (1) KR101415660B1 (en)
CN (2) CN107188960A (en)
ES (1) ES2817802T3 (en)
IN (1) IN2012DN00338A (en)
SG (1) SG177577A1 (en)
WO (1) WO2011017514A1 (en)

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US9096648B2 (en) * 2011-08-19 2015-08-04 Emd Millipore Corporation Methods of reducing level of one or more impurities in a sample during protein purification
WO2013033517A1 (en) * 2011-09-01 2013-03-07 Human Genome Sciences, Inc. Viral clearance methods
EP2578286A1 (en) 2011-10-04 2013-04-10 Merck Patent GmbH Method and apparatus for chromatographic purification
HUE035685T2 (en) * 2011-11-02 2018-05-28 Hoffmann La Roche Overload and elution chromatography
WO2013075740A1 (en) 2011-11-23 2013-05-30 Sanofi Antibody purification method
CN102492040B (en) * 2011-12-29 2014-06-25 嘉和生物药业有限公司 Method for purifying anti-HER2 or/and anti-HER3 antibody proteins
SG10201701224UA (en) * 2012-03-12 2017-04-27 Merck Patent Gmbh Removal of protein aggregates from biopharmaceutical preparations in a flowthrough mode
EP2682168A1 (en) 2012-07-02 2014-01-08 Millipore Corporation Purification of biological molecules
JP6253584B2 (en) * 2012-08-27 2017-12-27 旭化成メディカル株式会社 Antibody purification method by temperature-responsive chromatography
SI2895188T1 (en) * 2012-09-11 2018-05-31 Coherus Biosciences, Inc. Correctly folded etanercept in high purity and excellent yield
EP2812091B1 (en) 2012-09-17 2021-03-10 W.R. Grace & CO. - CONN. Chromatography media and devices
US10421795B2 (en) 2012-12-17 2019-09-24 Merck Sharp & Dohme Corp. Process for purifying insulin and analogues thereof
EP2959509B1 (en) 2013-02-14 2018-05-23 Nanopareil, Llc Electrospun hybrid nanofibre felt, method for making the same, and method for purifying biomolecules
EP3301115B1 (en) * 2013-05-06 2021-11-10 Sanofi Continuous multistep process for purifying antibodies
US20150093800A1 (en) * 2013-09-05 2015-04-02 Genentech, Inc. Method for chromatography reuse
JPWO2015041218A1 (en) * 2013-09-17 2017-03-02 株式会社カネカ Novel antibody purification method and antibody obtained therefrom (Novel Antibody Purification Method), and novel antibody purification method using cation exchange group and novel antibody purification antibody method
JP6326499B2 (en) 2013-12-12 2018-05-16 イー・エム・デイー・ミリポア・コーポレイシヨン Protein separation using acrylamide-containing filters
JP6612242B2 (en) * 2014-02-14 2019-11-27 ジーイー・ヘルスケア・バイオサイエンス・アクチボラグ Automated multi-stage purification system and multi-stage chromatography purification method
PL3116891T3 (en) 2014-03-10 2020-07-27 Richter Gedeon Nyrt. Immunoglobulin purification using pre-cleaning steps
CN104826617B (en) * 2014-03-25 2017-06-13 西北大学 Difunctional mixed mode chromatographic stationary phases of a kind of WAX/HIC for Separation of Proteins and preparation method thereof
PL3137209T3 (en) 2014-05-02 2023-01-02 W.R. Grace & Co. - Conn. Functionalized support material and methods of making and using functionalized support material
WO2015198320A1 (en) * 2014-06-24 2015-12-30 Insight Biopharmaceuticals Ltd. Methods of purifying antibodies
DE102014010353B4 (en) 2014-07-10 2024-09-12 Sartorius Stedim Biotech Gmbh Device, use of this device and method for substance separation with improved utilization of the capacity of chromatographic media
EP3230299A1 (en) 2014-12-08 2017-10-18 EMD Millipore Corporation Mixed bed ion exchange adsorber
KR102566292B1 (en) 2015-06-05 2023-08-10 더블유.알. 그레이스 앤드 캄파니-콘. Adsorbent bioprocessing clarifiers and methods of making and using the same
JP7163187B2 (en) * 2016-04-05 2022-10-31 ヘモネティクス・コーポレーション Method and apparatus for concentration of immunoglobulins from blood
CN107964044B (en) * 2016-10-19 2021-11-19 无锡科捷诺生物科技有限责任公司 Method for purifying anti-CD 20 monoclonal antibody from milk sample
WO2019183334A1 (en) 2018-03-21 2019-09-26 Waters Technologies Corporation Non-antibody high-affinity-based sample preparation, sorbents, devices and methods
EP3546475A1 (en) 2018-03-27 2019-10-02 Sanofi Full flow-through process for purifying recombinant proteins
WO2020125757A1 (en) * 2018-12-21 2020-06-25 Wuxi Biologics (Shanghai) Co., Ltd. A method for improving aggregate removal by protein a chromatography
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TW202128264A (en) * 2019-09-25 2021-08-01 瑞士商赫孚孟拉羅股份公司 Cation chromatography using predicted elution buffer salt concentration
CA3156649A1 (en) * 2019-10-04 2021-04-08 Merck Patent Gmbh Purification of proteins and viral inactivation
CN110724204B (en) * 2019-11-18 2021-10-22 广东菲鹏制药股份有限公司 Purification method of Fc fusion protein
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Also Published As

Publication number Publication date
JP6335838B2 (en) 2018-05-30
SG177577A1 (en) 2012-03-29
EP2462157A1 (en) 2012-06-13
KR101415660B1 (en) 2014-07-16
CN102574911A (en) 2012-07-11
CN102574911B (en) 2017-06-06
WO2011017514A1 (en) 2011-02-10
US8536316B2 (en) 2013-09-17
CN107188960A (en) 2017-09-22
ES2817802T3 (en) 2021-04-08
JP5791602B2 (en) 2015-10-07
JP2015157846A (en) 2015-09-03
US20110065901A1 (en) 2011-03-17
KR20120089432A (en) 2012-08-10
EP2462157A4 (en) 2012-12-26
EP2462157B1 (en) 2020-06-17
JP2013501721A (en) 2013-01-17

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