IN2012DN00403A - - Google Patents

Download PDF

Info

Publication number
IN2012DN00403A
IN2012DN00403A IN403DEN2012A IN2012DN00403A IN 2012DN00403 A IN2012DN00403 A IN 2012DN00403A IN 403DEN2012 A IN403DEN2012 A IN 403DEN2012A IN 2012DN00403 A IN2012DN00403 A IN 2012DN00403A
Authority
IN
India
Prior art keywords
nucleic acid
acid molecule
seq
encodes
terpene synthase
Prior art date
Application number
Inventor
Katherine Grace Zulak
Christopher Jones
Jessie Moniodia
Joerg Bohlmann
Original Assignee
Univ Western Australia
Forest Products Commission
Univ British Columbia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AU2009903016A external-priority patent/AU2009903016A0/en
Application filed by Univ Western Australia, Forest Products Commission, Univ British Columbia filed Critical Univ Western Australia
Publication of IN2012DN00403A publication Critical patent/IN2012DN00403A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P5/00—Preparation of hydrocarbons or halogenated hydrocarbons
    • C12P5/007—Preparation of hydrocarbons or halogenated hydrocarbons containing one or more isoprene units, i.e. terpenes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P15/00—Preparation of compounds containing at least three condensed carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/527—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving lyase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/6895—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for plants, fungi or algae
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/573—Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y402/00—Carbon-oxygen lyases (4.2)
    • C12Y402/03—Carbon-oxygen lyases (4.2) acting on phosphates (4.2.3)
    • C12Y402/03081—Exo-alpha-bergamotene synthase (4.2.3.81)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y402/00—Carbon-oxygen lyases (4.2)
    • C12Y402/03—Carbon-oxygen lyases (4.2) acting on phosphates (4.2.3)
    • C12Y402/03082—Alpha-santalene synthase (4.2.3.82)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y402/00—Carbon-oxygen lyases (4.2)
    • C12Y402/03—Carbon-oxygen lyases (4.2) acting on phosphates (4.2.3)
    • C12Y402/03083—Beta-santalene synthase (4.2.3.83)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Botany (AREA)
  • Mycology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

An isolated nucleic acid molecule that encodes a terpene synthase and is selected from among: a) a nucleic acid molecule comprising the sequence of nucleotides set forth in SEQ ID NO: 1, SEQ ID NO: 3 or SEQ ID NO: 5; b) a nucleic acid molecule that is a fragment of (a); c) a nucleic acid molecule comprising a sequence of nucleotides that is complementary to (a)-or (b); and d) a nucleic acid molecule that encodes a terpene synthase having at least or at least about or at least about 60%, 65%, 70%, 75%, 80%, 85%, 90%, 95%, 96%, 97%, 98%, 99% identity to any one of (a)-(c); wherein the nucleic acid molecule encodes a terpene synthase.
IN403DEN2012 2009-06-29 2010-06-25 IN2012DN00403A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AU2009903016A AU2009903016A0 (en) 2009-06-29 Novel Gene and Product
PCT/AU2010/000802 WO2011000026A1 (en) 2009-06-29 2010-06-25 Terpene synthases from santalum

Publications (1)

Publication Number Publication Date
IN2012DN00403A true IN2012DN00403A (en) 2015-08-21

Family

ID=43410351

Family Applications (1)

Application Number Title Priority Date Filing Date
IN403DEN2012 IN2012DN00403A (en) 2009-06-29 2010-06-25

Country Status (8)

Country Link
US (3) US8569025B2 (en)
EP (1) EP2449107B1 (en)
CN (1) CN102725410B (en)
BR (1) BRPI1014137A2 (en)
CA (1) CA2766810C (en)
IL (1) IL217221A0 (en)
IN (1) IN2012DN00403A (en)
WO (1) WO2011000026A1 (en)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009132220A2 (en) 2008-04-23 2009-10-29 Danisco Us Inc. Isoprene synthase variants for improved microbial production of isoprene
ES2626456T3 (en) * 2008-12-11 2017-07-25 Firmenich Sa Enzymatic procedure to produce beta-santalene and the corresponding enzyme
AU2015201051B2 (en) * 2008-12-11 2017-03-02 Firmenich Sa Method for producing beta-santalene
US8518686B2 (en) 2009-04-23 2013-08-27 Danisco Us Inc. Three-dimensional structure of isoprene synthase and its use thereof for generating variants
EP2449107B1 (en) 2009-06-29 2015-04-08 The University Of Western Australia Terpene synthases from santalum
CA2816306A1 (en) 2010-10-27 2012-05-03 Danisco Us Inc. Isoprene synthase variants for improved production of isoprene
JP2013544084A (en) 2010-10-29 2013-12-12 アリリクス・インコーポレイテッド Modified valencene synthase polypeptide, coding nucleic acid molecule and uses thereof
HK1201297A1 (en) 2011-11-21 2015-08-28 The University Of British Columbia Diterpene synthases and method for producing diterpenoids
US9550815B2 (en) 2012-01-23 2017-01-24 University Of British Columbia ABC terpenoid transporters and methods of using the same
US9163263B2 (en) 2012-05-02 2015-10-20 The Goodyear Tire & Rubber Company Identification of isoprene synthase variants with improved properties for the production of isoprene
CN105121647A (en) * 2012-11-01 2015-12-02 不列颠哥伦比亚大学 Cytochrome p450 and cytochrome p450 reductase polypeptides, encoding nucleic acid molecules and uses thereof
WO2014150599A1 (en) 2013-03-14 2014-09-25 Allylix, Inc. Valencene synthase polypeptides, encoding nucleic acid molecules and uses thereof
US9714418B2 (en) * 2014-03-31 2017-07-25 Evolva, Inc. Modified santalene synthase polypeptides, encoding nucleic acid molecules and uses thereof
WO2016087179A1 (en) 2014-12-02 2016-06-09 Firmenich Sa Intermediates and process for the preparation of sandalwood oil building blocks
CN108239630B (en) * 2016-12-27 2021-07-16 武汉臻智生物科技有限公司 Method for modifying terpene synthase
US20220315911A1 (en) * 2017-03-02 2022-10-06 Isobionics B.V. Santalene synthase
NL2018457B1 (en) 2017-03-02 2018-09-21 Isobionics B V Santalene Synthase
NL2019473B1 (en) 2017-09-01 2019-03-11 Isobionics B V Terpene Synthase producing patchoulol and elemol, and preferably also pogostol
CN110093329B (en) * 2018-01-30 2023-07-04 深圳艾格鑫科技有限公司 Terpene synthase and application thereof
CN108660128B (en) * 2018-05-18 2021-07-13 江苏省农业科学院 A kind of alfalfa terpene synthase, its encoding gene, vector, polyclonal antibody and application thereof
CN111434773B (en) * 2019-01-15 2021-06-18 天津大学 A kind of recombinant yeast with high yield of sandalwood oil and its construction method and application
CN111073941B (en) * 2019-09-12 2022-10-14 天津芸熙生物技术有限公司 Preparation process of sandalwood polypeptide
CN112852650B (en) * 2019-11-27 2023-04-14 暨南大学 A kind of Saccharomyces cerevisiae engineered bacteria with high production of santalene and santalol and its construction method and application
CN113544245A (en) * 2019-12-23 2021-10-22 弗门尼舍有限公司 Biochemical production of sandalwood oil
EP4162061A1 (en) 2020-06-04 2023-04-12 Isobionics B.V. Synthetic santalene synthases
CN112410362A (en) * 2020-11-06 2021-02-26 浙江万里学院 Rhododendron micranthum TPS gene, primer for cloning Rhododendron micranthum TPS gene, cloning method and application thereof
CN112831519B (en) * 2020-12-28 2022-10-21 上海交通大学 Method for preparing santalol by utilizing sweet wormwood herbs
CN113025594B (en) * 2021-03-04 2022-05-31 安徽农业大学 Polypeptide, nucleic acid and application of polypeptide and nucleic acid in synthesis of geraniol
CN114457067B (en) * 2022-02-10 2024-10-25 中国科学院天津工业生物技术研究所 A low-cost and rapid method to remove errors in DNA synthesis
CN117327717B (en) * 2023-10-25 2026-07-31 杭州欣贝莱生物科技有限公司 Gene and biological enzyme for catalytic synthesis of camphene and application of gene and biological enzyme in camphene production
CN118812684B (en) * 2024-09-03 2025-06-13 广西壮族自治区农业科学院 SaERF89 gene from Santalum album and its application in biosynthesis of α-bisabolol
CN119039411B (en) * 2024-09-12 2025-12-12 广西壮族自治区农业科学院 Sandalwood SaERF89 gene and its application in the biosynthesis of (Z)-α-trans-bergamotol

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3654090A (en) 1968-09-24 1972-04-04 Organon Method for the determination of antigens and antibodies
NL154598B (en) 1970-11-10 1977-09-15 Organon Nv PROCEDURE FOR DETERMINING AND DETERMINING LOW MOLECULAR COMPOUNDS AND PROTEINS THAT CAN SPECIFICALLY BIND THESE COMPOUNDS AND TEST PACKAGING.
US4016043A (en) 1975-09-04 1977-04-05 Akzona Incorporated Enzymatic immunological method for the determination of antigens and antibodies
US5837832A (en) 1993-06-25 1998-11-17 Affymetrix, Inc. Arrays of nucleic acid probes on biological chips
SE9602545L (en) 1996-06-25 1997-12-26 Michael Mecklenburg Method of discriminating complex biological samples
AU7164998A (en) 1997-04-28 1998-11-24 B-E Safe, Inc. Taxonomic identification of microorganisms, proteins and peptides involved in vertebrate disease states
US6265639B1 (en) 1998-01-22 2001-07-24 Washington State University Foundation Gymnosperm nucleic acid molecules encoding sesquiterpene synthases and methods of use
US6531303B1 (en) 1998-07-06 2003-03-11 Arkion Life Sciences Llc Method of producing geranylgeraniol
ATE546521T1 (en) 2002-10-04 2012-03-15 Firmenich & Cie SESQUITERPENE SYNTHASES AND METHODS OF USE
FR2881143B1 (en) 2005-01-27 2010-12-17 Librophyt SYSTEM FOR PRODUCING TERPENOIDS IN PLANTS
EP2311940B1 (en) * 2005-06-17 2017-08-09 Firmenich SA Novel sesquiterpene synthases and methods of their use
WO2009044336A2 (en) 2007-10-05 2009-04-09 Firmenich Sa Method for producing diterpenes
WO2009109597A1 (en) 2008-03-06 2009-09-11 Firmenich Sa Method for producing alpha- santalene
ES2626456T3 (en) 2008-12-11 2017-07-25 Firmenich Sa Enzymatic procedure to produce beta-santalene and the corresponding enzyme
EP2449107B1 (en) 2009-06-29 2015-04-08 The University Of Western Australia Terpene synthases from santalum
HK1201297A1 (en) 2011-11-21 2015-08-28 The University Of British Columbia Diterpene synthases and method for producing diterpenoids
US9550815B2 (en) 2012-01-23 2017-01-24 University Of British Columbia ABC terpenoid transporters and methods of using the same

Also Published As

Publication number Publication date
WO2011000026A1 (en) 2011-01-06
US8569025B2 (en) 2013-10-29
EP2449107A1 (en) 2012-05-09
EP2449107A4 (en) 2013-01-02
CA2766810A1 (en) 2011-01-06
CA2766810C (en) 2017-10-10
US20140196166A1 (en) 2014-07-10
US20150167021A1 (en) 2015-06-18
BRPI1014137A2 (en) 2015-08-25
CN102725410A (en) 2012-10-10
CN102725410B (en) 2016-03-16
US20120208173A1 (en) 2012-08-16
IL217221A0 (en) 2012-02-29
US9260728B2 (en) 2016-02-16
US8993284B2 (en) 2015-03-31
EP2449107B1 (en) 2015-04-08

Similar Documents

Publication Publication Date Title
WO2010127304A3 (en) Sequencing methods
EA201490534A1 (en) METHODS OF SWORDING DNA CODED LIBRARIES
WO2008052101A3 (en) Multiplex automated genome engineering
WO2011012316A3 (en) Rna with a combination of unmodified and modified nucleotides for protein expression
NZ607870A (en) Lactococcus crispr-cas sequences
MX346862B (en) SEQUENCES CONSENSUS OF HIV ENVELOPE AND METHOD TO USE THE SAME.
MX2009012846A (en) Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same.
WO2009012263A3 (en) Tissue-specific micrornas and compositions and uses thereof
WO2010018563A3 (en) Compositions and methods for the prognosis of lymphoma
MX2012003473A (en) Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same.
WO2008067423A3 (en) Methods of improving the introduction of dna into bacterial cells
WO2007112097A3 (en) Novel signature self renewal gene expression programs
WO2008078180A3 (en) Materials and methods for the generation of transcripts comprising modified nucleotides
WO2010135836A8 (en) Novel beta-glucosidase enzymes
NZ583783A (en) Avian interferon-lambda polypeptide and genetic sequences encoding the same
MX2010003109A (en) C5a BINDING NUCLEIC ACIDS.
MX2020005724A (en) Alpha-amylase variants and polynucleotides encoding same.
EP4253534A3 (en) Alpha-amylase variants and polynucleotides encoding same
MX2009000656A (en) Sdf-i binding nucleic acids.
NZ588658A (en) Aberrant mitochondrial dna, associated fusion transcripts and hybridization probes therefor
MX351107B (en) Mcp-i binding nucleic acids.
WO2008146745A1 (en) Novel lysophosphatidate acyltransferase gene
MX346019B (en) Kit for detecting bovine leukemia virus(blv), and use thereof.
MX337913B (en) Polypeptides having cellobiohydrolase activity and polynucleotides encoding same.
IN2015DN03206A (en)