IN2012DN01224A - - Google Patents

Info

Publication number
IN2012DN01224A
IN2012DN01224A IN1224DEN2012A IN2012DN01224A IN 2012DN01224 A IN2012DN01224 A IN 2012DN01224A IN 1224DEN2012 A IN1224DEN2012 A IN 1224DEN2012A IN 2012DN01224 A IN2012DN01224 A IN 2012DN01224A
Authority
IN
India
Prior art keywords
biofilm
oral care
sesquiterpenoid
disclosed
antimicrobial agent
Prior art date
Application number
Inventor
Lyndsay Schaeffer-Korbylo
Andre Michelle Morgan
Davide Miksa
Laurence Du-Thumm
Michael Prencipe
Gregory Szewczyk
Evangelia Stelios Arvanitidou
Original Assignee
Colgate Palmolive Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Colgate Palmolive Co filed Critical Colgate Palmolive Co
Publication of IN2012DN01224A publication Critical patent/IN2012DN01224A/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N49/00Biocides, pest repellants or attractants, or plant growth regulators, containing compounds containing the group, wherein m+n>=1, both X together may also mean —Y— or a direct carbon-to-carbon bond, and the carbon atoms marked with an asterisk are not part of any ring system other than that which may be formed by the atoms X, the carbon atoms in square brackets being part of any acyclic or cyclic structure, or the group, wherein A means a carbon atom or Y, n>=0, and not more than one of these carbon atoms being a member of the same ring system, e.g. juvenile insect hormones or mimics thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/20Halogens; Compounds thereof
    • A61K8/21Fluorides; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • A61K8/342Alcohols having more than seven atoms in an unbroken chain
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • A61K8/347Phenols
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/35Ketones, e.g. benzophenone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/36Carboxylic acids; Salts or anhydrides thereof
    • A61K8/365Hydroxycarboxylic acids; Ketocarboxylic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4906Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
    • A61K8/4926Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having six membered rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9789Magnoliopsida [dicotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/92Oral administration

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Emergency Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Inorganic Chemistry (AREA)
  • Environmental Sciences (AREA)
  • Agronomy & Crop Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Dentistry (AREA)
  • Plant Pathology (AREA)
  • Pest Control & Pesticides (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Insects & Arthropods (AREA)
  • Botany (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Cosmetics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Natural Medicines & Medicinal Plants (AREA)

Abstract

Disclosed are oral care compositions and the use of such oral care compositions for treating conditions caused by biofilm formation. Also disclosed are methods for inhibiting biofilm formation and/or degrading biofilm. The oral care composition includes a sesquiterpenoid and an antimicrobial agent, in which the sesquiterpenoid and the antimicrobial agent are present in an amount effective to inhibit and/or degrade a biofilm in the oral cavity.
IN1224DEN2012 2009-08-12 2009-08-12 IN2012DN01224A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2009/053500 WO2011019342A2 (en) 2009-08-12 2009-08-12 Oral care composition

Publications (1)

Publication Number Publication Date
IN2012DN01224A true IN2012DN01224A (en) 2015-04-10

Family

ID=43415319

Family Applications (1)

Application Number Title Priority Date Filing Date
IN1224DEN2012 IN2012DN01224A (en) 2009-08-12 2009-08-12

Country Status (15)

Country Link
US (2) US8906349B2 (en)
EP (1) EP2464328B1 (en)
JP (1) JP2013501782A (en)
CN (1) CN102625691B (en)
AR (1) AR077861A1 (en)
AU (1) AU2009351103B2 (en)
BR (1) BR112012002992A2 (en)
CA (1) CA2770920C (en)
IN (1) IN2012DN01224A (en)
MX (1) MX2012001800A (en)
RU (1) RU2526913C2 (en)
SG (1) SG178166A1 (en)
TW (1) TWI394591B (en)
WO (1) WO2011019342A2 (en)
ZA (1) ZA201201006B (en)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8513305B2 (en) 2007-05-14 2013-08-20 Research Foundation Of State University Of New York Induction of a physiological dispersion response in bacterial cells in a biofilm
JP5852007B2 (en) 2009-12-18 2016-02-03 コルゲート・パーモリブ・カンパニーColgate−Palmolive Company Chalcones as enhancers of antimicrobial agents
MX2012007876A (en) 2010-01-07 2012-08-03 Colgate Palmolive Co Color change of chalcone-containing oral care formulations.
AU2011357782B2 (en) * 2011-01-31 2015-07-02 Colgate-Palmolive Company Oral care compositions
CN104066417B (en) 2011-12-02 2017-02-15 高露洁-棕榄公司 Oral care composition comprising isobutyl magnolol
JP5992304B2 (en) * 2011-12-13 2016-09-14 大正製薬株式会社 Oral body odor improving composition
US20130315843A1 (en) * 2012-05-25 2013-11-28 The Procter & Gamble Company Composition for reduction of trpa1 and trpv1 sensations
RU2500384C1 (en) * 2012-08-16 2013-12-10 Общество с ограниченной ответственностью Концерн "КАЛИНА" Mouth rinse formulation
CN104822422B (en) * 2012-12-03 2018-03-13 高露洁-棕榄公司 For treating the composition and method of carious tooth
WO2014151567A1 (en) 2013-03-15 2014-09-25 Colgate-Palmolive Company Oral care compositions containing deoxy sugar antimetabolites
CN105283166B (en) * 2013-06-18 2018-07-17 高露洁-棕榄公司 Include the antimicrobial compositions of essential oil combination
CN103913853A (en) * 2013-07-05 2014-07-09 马准吾 Contact lens having cooling coating layer
EP3188707B1 (en) * 2014-09-01 2022-05-11 Colgate-Palmolive Company Zinc-containing compositions with essential oils
US9782333B2 (en) * 2015-01-21 2017-10-10 Chattem Inc. Oral composition for xerostomia
CN117224709A (en) * 2016-05-12 2023-12-15 宾夕法尼亚州立大学托管会 Compositions and methods for inhibiting biofilm deposition and production
EP3468530A4 (en) 2016-06-10 2020-03-11 Clarity Cosmetics Inc. NON-COMEDOGENOUS HAIR AND SCALP CARE FORMULATIONS AND METHOD OF USE
BR112018075118A2 (en) * 2016-06-24 2019-03-26 Colgate-Palmolive Company a oral care composition
US10335615B2 (en) 2016-06-24 2019-07-02 Colgate-Palmolive Company Oral care compositions and methods of use
EP3512607B1 (en) 2016-10-20 2024-02-14 Colgate-Palmolive Company Antimicrobial compositions for oral care or cleansing, and methods for anti-attachment polymers and coatings
US11198972B2 (en) 2016-10-25 2021-12-14 The Procter & Gamble Company Fibrous structures
WO2018081191A1 (en) 2016-10-25 2018-05-03 The Procter & Gamble Company Differential pillow height fibrous structures
CN106581159B (en) * 2017-01-24 2020-05-12 广州薇美姿实业有限公司 Oral care composition for children and morning and evening benefiting combined toothpaste for children
EP3454877A4 (en) * 2017-05-12 2019-12-04 The Trustees of The University of Pennsylvania COMPOSITIONS AND METHODS FOR INHIBITING DEPOSITION AND PRODUCTION OF BIOFILMS
CN117941682A (en) * 2017-12-22 2024-04-30 联合利华知识产权控股有限公司 Antimicrobial compositions
RU2691410C1 (en) * 2018-04-26 2019-06-13 Федеральное государственное бюджетное учреждение науки "Институт морских биологических исследований имени А.О. Ковалевского РАН" Oral and throat care means
US11541105B2 (en) 2018-06-01 2023-01-03 The Research Foundation For The State University Of New York Compositions and methods for disrupting biofilm formation and maintenance
WO2019239357A1 (en) * 2018-06-12 2019-12-19 Buzzelet Development And Technologies Ltd Dental care cannabis device and use thereof
WO2020126347A1 (en) 2018-12-18 2020-06-25 Unilever N.V. An antimicrobial composition
WO2020126317A1 (en) 2018-12-21 2020-06-25 Unilever N.V. Antimicrobial compositions comprising modified clay and nonionic triblock copolymers
EP3897531B1 (en) * 2018-12-21 2025-07-09 Unilever IP Holdings B.V. Antimicrobial compositions comprising modified clay and biphenol
US20220071877A1 (en) * 2018-12-26 2022-03-10 Colgate-Palmolive Company Methods of Shifting Biofilm in the Oral Cavity from Pathogenic to Healthy Biofilm
US20220401395A1 (en) * 2019-08-26 2022-12-22 Isp Investments Llc Mucoadhesive compositions and method of use thereof
JP2024047742A (en) * 2022-09-27 2024-04-08 ライオン株式会社 Dentifrice Composition
WO2026087025A1 (en) * 2024-10-21 2026-04-30 Symrise Ag Anti-caries oral hygiene composition

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4294894A (en) * 1979-01-15 1981-10-13 E. R. Squibb & Sons, Inc. Transparent toothpaste having a medicinal action and process for its production
JPS58213706A (en) * 1982-06-08 1983-12-12 Lion Corp Agent for inhibiting dental plaque formation
JPS6333326A (en) 1986-07-29 1988-02-13 Kao Corp Antibacterial composition
US5256401A (en) * 1987-01-30 1993-10-26 Colgate-Palmolive Company Antibacterial antiplaque mouthwash composition
JP2605714B2 (en) * 1987-05-11 1997-04-30 ライオン株式会社 Oral composition
JPH01151512A (en) 1988-07-21 1989-06-14 Tsurui Yakuhin Kogyo Kk Preventive agent for dental caries
US5424059A (en) * 1988-12-29 1995-06-13 Colgate Palmolive Company Antibacterial antiplaque dentifrice
US5116602A (en) 1989-09-27 1992-05-26 Colgate-Palmolive Company Antiplaque oral compositions
JPH04202121A (en) 1990-11-29 1992-07-22 Sunstar Inc Cetylpyridinium chloride-containing antimicrobial composition for oral cavity
JP3803695B2 (en) * 1994-11-28 2006-08-02 サンスター株式会社 Antibacterial preparation
US6319958B1 (en) 1998-06-22 2001-11-20 Wisconsin Alumni Research Foundation Method of sensitizing microbial cells to antimicrobial compound
WO2000062744A2 (en) 1999-04-19 2000-10-26 The Procter & Gamble Company Skin care compositions containing combination of skin care actives
US20040057908A1 (en) 2001-12-13 2004-03-25 Bowen William H. Oral compositions and use thereof
US6998112B2 (en) * 2003-03-18 2006-02-14 Arthur Zuckerman Sleep inducing toothpaste made with natural herbs and a natural hormone
US20040208908A1 (en) * 2003-04-16 2004-10-21 The Trustees Of Columbia University In The City Of New York Antimicrobial medical articles containing a synergistic combination of anti-infective compounds and octoxyglycerin
RU2241438C1 (en) 2003-05-29 2004-12-10 Закрытое акционерное общество "Модум" Tooth paste composition
JP2005015369A (en) * 2003-06-25 2005-01-20 Lion Corp Oral composition
BRPI0412675A (en) * 2003-07-17 2006-10-03 Univ Columbia antimicrobial compositions containing synergistic combinations of quaternary ammonium compounds and essential oils and / or constituents
JP2005298357A (en) 2004-04-07 2005-10-27 Lion Corp Oral composition
JP2007008843A (en) 2005-06-29 2007-01-18 Lion Corp Dentifrice composition and method for preventing discoloration of dentifrice composition
WO2007042472A1 (en) 2005-10-14 2007-04-19 Symrise Gmbh & Co. Kg Synergistic mixtures of bisabolol and ginger extract
US20090226384A1 (en) 2006-01-03 2009-09-10 Cavinkare Private Limited Antimicrobial composition containing triclosan and at least one functionalized hydrocarbon
RU2006135434A (en) 2006-10-06 2008-04-20 Сергей Борисович Улитовский (RU) DENTAL PASTE CONTAINING PAPAIN, LACTOPEROXIDASE AND LACTOSE ENZYMES
ITMI20071136A1 (en) * 2007-06-04 2008-12-05 Velleja Res Srl TOPIC FORMULATIONS FOR THE PREVENTION AND TREATMENT OF THE INFLAMMATORY AND / OR INFECTIOUS STATES OF THE GENITAL AREA
JP2009149535A (en) 2007-12-19 2009-07-09 Lion Corp Oral composition
US9724541B2 (en) * 2009-04-06 2017-08-08 Lisa Marie Kao Dental cleaning and polishing composition comprising diamond particles

Also Published As

Publication number Publication date
CN102625691A (en) 2012-08-01
BR112012002992A2 (en) 2016-04-19
ZA201201006B (en) 2014-07-30
CA2770920A1 (en) 2011-02-17
CN102625691B (en) 2015-07-22
US20150157542A1 (en) 2015-06-11
CA2770920C (en) 2014-07-22
JP2013501782A (en) 2013-01-17
TW201124173A (en) 2011-07-16
RU2526913C2 (en) 2014-08-27
SG178166A1 (en) 2012-03-29
MX2012001800A (en) 2012-03-14
TWI394591B (en) 2013-05-01
WO2011019342A2 (en) 2011-02-17
RU2012108729A (en) 2013-09-20
EP2464328B1 (en) 2016-03-30
US8906349B2 (en) 2014-12-09
AR077861A1 (en) 2011-09-28
US20120128599A1 (en) 2012-05-24
US9889077B2 (en) 2018-02-13
EP2464328A2 (en) 2012-06-20
AU2009351103B2 (en) 2013-05-23
AU2009351103A1 (en) 2012-02-23
WO2011019342A3 (en) 2011-04-07

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