IN2012DN01932A - - Google Patents
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- Publication number
- IN2012DN01932A IN2012DN01932A IN1932DEN2012A IN2012DN01932A IN 2012DN01932 A IN2012DN01932 A IN 2012DN01932A IN 1932DEN2012 A IN1932DEN2012 A IN 1932DEN2012A IN 2012DN01932 A IN2012DN01932 A IN 2012DN01932A
- Authority
- IN
- India
- Prior art keywords
- receptor
- micrornas
- cell
- virus
- infection
- Prior art date
Links
- 108700011259 MicroRNAs Proteins 0.000 abstract 6
- 241000700605 Viruses Species 0.000 abstract 5
- 208000015181 infectious disease Diseases 0.000 abstract 3
- 108020004999 messenger RNA Proteins 0.000 abstract 2
- 238000000338 in vitro Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000002679 microRNA Substances 0.000 abstract 1
- 238000012986 modification Methods 0.000 abstract 1
- 230000004048 modification Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
The invention relates to an in vitro method for identifying microRNAs or the target mRNAs thereof, the expression of which during the infection of cells by a virus using a cell receptor and at least one cell co-receptor for entering the cell, is specifically modified on the basis of the cell co-receptor used by the virus for its entering the cells, comprising: i) determining the microRNA expression levels in a test cell expressing a receptor, a first co-receptor and at least one other co-receptor, after infection by a first virus using the first co-receptor and by at least one other virus using another co-receptor, respectively; ii) identifying the microRNAs, the expression level of which is modulated during the infection by each of the viruses in relation to the expression level in the uninfected cells; iii) comparing the thus-identified microRNAs; iv) selecting the microRNAs, the modification of the expression level of which is specific to the use of a co-receptor; v) optionally identifying the target mRNAs of the thus-selected microRNAs.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0956045A FR2949789B1 (en) | 2009-09-04 | 2009-09-04 | IDENTIFICATION OF CELLULAR TROPISM OF VIRUSES |
| PCT/FR2010/051817 WO2011027075A1 (en) | 2009-09-04 | 2010-09-01 | Identifying viral cell tropism |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IN2012DN01932A true IN2012DN01932A (en) | 2015-07-24 |
Family
ID=42077918
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN1932DEN2012 IN2012DN01932A (en) | 2009-09-04 | 2010-09-01 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US9175334B2 (en) |
| EP (1) | EP2473629B8 (en) |
| JP (1) | JP5837496B2 (en) |
| CN (1) | CN102812131B (en) |
| AU (1) | AU2010291028B2 (en) |
| CA (1) | CA2773068A1 (en) |
| ES (1) | ES2537121T3 (en) |
| FR (1) | FR2949789B1 (en) |
| IN (1) | IN2012DN01932A (en) |
| WO (1) | WO2011027075A1 (en) |
| ZA (1) | ZA201202432B (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2624808T3 (en) * | 2011-05-11 | 2017-07-17 | The Regents Of The University Of Michigan | MDM2 spirooxindol antagonists |
| CA2867420A1 (en) * | 2012-03-19 | 2013-09-26 | Prestizia | Methods for determining the tropism and receptor usage of a virus, in particular hiv, in body samples taken from the circulation |
| EP2813578A1 (en) * | 2013-06-14 | 2014-12-17 | Prestizia | Methods for detecting an infectious agent, in particular HIV1, using long noncoding RNA |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7393634B1 (en) * | 1999-10-12 | 2008-07-01 | United States Of America As Represented By The Secretary Of The Air Force | Screening for disease susceptibility by genotyping the CCR5 and CCR2 genes |
| WO2009033185A1 (en) * | 2007-09-06 | 2009-03-12 | University Of Massachusetts | Virus-specific mirna signatures for diagnosis and therapeutic treatment of viral infection |
-
2009
- 2009-09-04 FR FR0956045A patent/FR2949789B1/en not_active Expired - Fee Related
-
2010
- 2010-09-01 EP EP20100763790 patent/EP2473629B8/en not_active Not-in-force
- 2010-09-01 ES ES10763790.2T patent/ES2537121T3/en active Active
- 2010-09-01 CN CN201080050205.0A patent/CN102812131B/en not_active Expired - Fee Related
- 2010-09-01 JP JP2012527369A patent/JP5837496B2/en not_active Expired - Fee Related
- 2010-09-01 CA CA2773068A patent/CA2773068A1/en not_active Abandoned
- 2010-09-01 US US13/394,002 patent/US9175334B2/en not_active Expired - Fee Related
- 2010-09-01 IN IN1932DEN2012 patent/IN2012DN01932A/en unknown
- 2010-09-01 WO PCT/FR2010/051817 patent/WO2011027075A1/en not_active Ceased
- 2010-09-01 AU AU2010291028A patent/AU2010291028B2/en not_active Ceased
-
2012
- 2012-04-03 ZA ZA2012/02432A patent/ZA201202432B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| FR2949789A1 (en) | 2011-03-11 |
| CA2773068A1 (en) | 2011-03-10 |
| US20130040832A1 (en) | 2013-02-14 |
| ES2537121T3 (en) | 2015-06-02 |
| WO2011027075A1 (en) | 2011-03-10 |
| EP2473629A1 (en) | 2012-07-11 |
| EP2473629B1 (en) | 2015-02-25 |
| AU2010291028B2 (en) | 2015-11-19 |
| JP2013503620A (en) | 2013-02-04 |
| CN102812131B (en) | 2016-08-10 |
| AU2010291028A1 (en) | 2012-04-19 |
| US9175334B2 (en) | 2015-11-03 |
| EP2473629B8 (en) | 2015-05-13 |
| CN102812131A (en) | 2012-12-05 |
| FR2949789B1 (en) | 2011-12-09 |
| JP5837496B2 (en) | 2015-12-24 |
| ZA201202432B (en) | 2012-12-27 |
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