IN2012DN02073A - - Google Patents

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Publication number
IN2012DN02073A
IN2012DN02073A IN2073DEN2012A IN2012DN02073A IN 2012DN02073 A IN2012DN02073 A IN 2012DN02073A IN 2073DEN2012 A IN2073DEN2012 A IN 2073DEN2012A IN 2012DN02073 A IN2012DN02073 A IN 2012DN02073A
Authority
IN
India
Prior art keywords
hcg
including recombinant
preparations including
preparations
recombinant hcg
Prior art date
Application number
Inventor
Ian Cottingham
Daniel Plaksin
Richard Boyd White
Original Assignee
Ferring Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ferring Bv filed Critical Ferring Bv
Publication of IN2012DN02073A publication Critical patent/IN2012DN02073A/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/24—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g. HCG; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/59—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g.hCG [human chorionic gonadotropin]; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1048—Glycosyltransferases (2.4)
    • C12N9/1081—Glycosyltransferases (2.4) transferring other glycosyl groups (2.4.99)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/005—Glycopeptides, glycoproteins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y204/00—Glycosyltransferases (2.4)
    • C12Y204/99—Glycosyltransferases (2.4) transferring other glycosyl groups (2.4.99)

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Endocrinology (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Reproductive Health (AREA)
  • Wood Science & Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Toxicology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Gynecology & Obstetrics (AREA)
  • Diabetes (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Preparations including recombinant HCG (r HCG).
IN2073DEN2012 2009-10-05 2010-10-04 IN2012DN02073A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP09252360 2009-10-05
PCT/GB2010/001854 WO2011042688A1 (en) 2009-10-05 2010-10-04 Pharmaceutical preparation comprising recombinant hcg

Publications (1)

Publication Number Publication Date
IN2012DN02073A true IN2012DN02073A (en) 2015-08-21

Family

ID=41471027

Family Applications (1)

Application Number Title Priority Date Filing Date
IN2073DEN2012 IN2012DN02073A (en) 2009-10-05 2010-10-04

Country Status (25)

Country Link
US (5) US8975226B2 (en)
EP (2) EP2486051B1 (en)
JP (6) JP6176924B2 (en)
KR (7) KR102489143B1 (en)
CN (1) CN107050434B (en)
AR (2) AR079876A1 (en)
AU (1) AU2010304922B2 (en)
BR (1) BR112012007990A2 (en)
CA (1) CA2776790A1 (en)
DK (1) DK2486051T3 (en)
ES (2) ES3036152T3 (en)
HR (1) HRP20200941T1 (en)
HU (1) HUE050793T2 (en)
IL (3) IL218548A (en)
IN (1) IN2012DN02073A (en)
JO (1) JOP20200039A1 (en)
LT (1) LT2486051T (en)
MX (1) MX2012003951A (en)
PL (1) PL2486051T3 (en)
PT (1) PT2486051T (en)
RS (1) RS60413B1 (en)
RU (2) RU2724528C2 (en)
SI (1) SI2486051T1 (en)
TW (2) TWI532495B (en)
WO (1) WO2011042688A1 (en)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI488640B (en) 2008-04-16 2015-06-21 菲瑞茵國際中心股份有限公司 Pharmaceutical preparation
TWI532495B (en) 2009-10-05 2016-05-11 菲瑞茵國際中心股份有限公司 Pharmaceutical preparation
WO2012131306A1 (en) 2011-03-31 2012-10-04 Ferring B.V. Pharmaceutical preparation
AR090095A1 (en) * 2011-06-06 2014-10-22 Ferring Bv PHARMACEUTICAL PREPARATION THAT INCLUDES STIMULATING HORMONE OF THE RECOMBINANT FOLICLE
JO3092B1 (en) * 2011-08-08 2017-03-15 Ferring Bv Complex for controlled stimulation of the ovary
WO2013093760A2 (en) * 2011-12-19 2013-06-27 Grifols, S.A. Compositions, methods, and kits for preparing sialylated recombinant proteins
SG10201704774VA (en) 2012-12-10 2017-07-28 Seikagaku Kogyo Co Ltd Novel recombinant factor c and method for producing the same, and method for measuring endotoxin
CN107429237B (en) * 2014-12-22 2021-09-28 豪夫迈·罗氏有限公司 CMP-dependent sialidase Activity
EA034022B1 (en) * 2015-04-24 2019-12-19 Ферринг Б.В. Method of production of gonadotrophin
MX381279B (en) 2015-06-26 2025-03-12 Ferring Bv VIRAL PURIFICATION AND/OR INACTIVATION METHODS.
US20210038694A1 (en) 2018-04-30 2021-02-11 Ferring B.V. Composition for controlled ovarian stimulation
US20210244821A1 (en) * 2020-02-05 2021-08-12 Novartis Ag Cho cell expressed het il-15
CN116199742B (en) * 2022-07-06 2025-01-24 华兰基因工程有限公司 A method for preparing recombinant human chorionic gonadotropin Fc fusion protein
KR102821987B1 (en) * 2024-10-24 2025-06-26 에이디텍 주식회사 Composition for treating infertility comprising beta core fragment hCG as an active ingredient

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TW518235B (en) * 1997-01-15 2003-01-21 Akzo Nobel Nv A gonadotropin-containing pharmaceutical composition with improved stability on prolong storage
BR9810478A (en) 1997-06-25 2000-09-12 Applied Research Systems Disulfide-crosslinked glycoprotein hormone analogs and their preparation and use
US6500627B1 (en) 1998-02-03 2002-12-31 The Trustees Of Columbia University In The City Of New York Methods for predicting pregnancy outcome in a subject by HCG assay
WO2003050286A1 (en) * 2001-10-29 2003-06-19 Crucell Holland B.V. Methods and means for producing proteins with predetermined post-translational modifications
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UA87433C2 (en) * 2001-10-22 2009-07-27 Еплайд Рісьорч Системз Ерс Холдінг Н.В. Gonadotropines for stimulation of folliculogenesis
CN100347306C (en) * 2001-10-29 2007-11-07 克鲁塞尔荷兰公司 Methods and means for producing proteins with predetermined post-translational modifications
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TWI532495B (en) 2009-10-05 2016-05-11 菲瑞茵國際中心股份有限公司 Pharmaceutical preparation
WO2012131306A1 (en) * 2011-03-31 2012-10-04 Ferring B.V. Pharmaceutical preparation
JO3092B1 (en) * 2011-08-08 2017-03-15 Ferring Bv Complex for controlled stimulation of the ovary

Also Published As

Publication number Publication date
IL218548A (en) 2017-03-30
HRP20200941T1 (en) 2020-09-18
JP6310440B2 (en) 2018-04-11
JOP20200039A1 (en) 2022-10-30
JP6580104B2 (en) 2019-09-25
RU2016118236A (en) 2018-10-29
ES3036152T3 (en) 2025-09-15
EP3611185A1 (en) 2020-02-19
US12234272B2 (en) 2025-02-25
JP2016074680A (en) 2016-05-12
KR20170133531A (en) 2017-12-05
CN107050434B (en) 2021-07-27
IL218548A0 (en) 2012-05-31
RU2588650C2 (en) 2016-07-10
US20220340634A1 (en) 2022-10-27
LT2486051T (en) 2020-07-10
JP2018076296A (en) 2018-05-17
CA2776790A1 (en) 2011-04-14
JP7292153B2 (en) 2023-06-16
KR20210141771A (en) 2021-11-23
KR102489143B1 (en) 2023-01-13
KR20230012104A (en) 2023-01-25
JP7196244B2 (en) 2022-12-26
KR101804479B1 (en) 2017-12-05
RS60413B1 (en) 2020-07-31
EP3611185B1 (en) 2025-04-30
DK2486051T3 (en) 2020-06-22
AU2010304922A1 (en) 2012-03-29
US20180030107A1 (en) 2018-02-01
KR20120094909A (en) 2012-08-27
TWI604850B (en) 2017-11-11
PL2486051T3 (en) 2020-09-07
US20130023476A1 (en) 2013-01-24
US20140249082A1 (en) 2014-09-04
ES2798258T3 (en) 2020-12-10
RU2016118236A3 (en) 2019-09-18
HUE050793T2 (en) 2021-01-28
US9676835B2 (en) 2017-06-13
IL250733A0 (en) 2017-04-30
KR102213154B1 (en) 2021-02-05
BR112012007990A2 (en) 2017-07-25
EP2486051A1 (en) 2012-08-15
KR20190028823A (en) 2019-03-19
IL267556A (en) 2019-08-29
JP2013506708A (en) 2013-02-28
KR20190067256A (en) 2019-06-14
JP6176924B2 (en) 2017-08-09
TWI532495B (en) 2016-05-11
AR079876A1 (en) 2012-02-29
KR20210014767A (en) 2021-02-09
CN107050434A (en) 2017-08-18
JP2021176867A (en) 2021-11-11
US11292824B2 (en) 2022-04-05
US10526390B2 (en) 2020-01-07
TW201113030A (en) 2011-04-16
RU2012112907A (en) 2013-11-10
MX2012003951A (en) 2012-05-29
AR125991A2 (en) 2023-08-30
US8975226B2 (en) 2015-03-10
PT2486051T (en) 2020-06-17
JP2023075144A (en) 2023-05-30
WO2011042688A1 (en) 2011-04-14
SI2486051T1 (en) 2020-08-31
CN102549011A (en) 2012-07-04
RU2724528C2 (en) 2020-06-23
TW201632198A (en) 2016-09-16
US20200247863A1 (en) 2020-08-06
AU2010304922B2 (en) 2014-11-06
IL250733B (en) 2019-07-31
KR101987982B1 (en) 2019-06-11
EP2486051B1 (en) 2020-03-25
JP2020000246A (en) 2020-01-09

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