IN2012DN06631A - - Google Patents
Info
- Publication number
- IN2012DN06631A IN2012DN06631A IN6631DEN2012A IN2012DN06631A IN 2012DN06631 A IN2012DN06631 A IN 2012DN06631A IN 6631DEN2012 A IN6631DEN2012 A IN 6631DEN2012A IN 2012DN06631 A IN2012DN06631 A IN 2012DN06631A
- Authority
- IN
- India
- Prior art keywords
- yloxy
- methyl
- isoxazol
- pyran
- piperidin
- Prior art date
Links
- WLLOFQROROXOMO-GOSISDBHSA-N 4-[[4-[[4-[(3r)-oxolan-3-yl]oxy-1,2-benzoxazol-3-yl]oxymethyl]piperidin-1-yl]methyl]oxan-4-ol Chemical compound C1CC(COC=2C3=C(O[C@H]4COCC4)C=CC=C3ON=2)CCN1CC1(O)CCOCC1 WLLOFQROROXOMO-GOSISDBHSA-N 0.000 abstract 1
- 208000015122 neurodegenerative disease Diseases 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
- A61K31/422—Oxazoles not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
- A61K31/423—Oxazoles condensed with carbocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Psychiatry (AREA)
- Epidemiology (AREA)
- Hospice & Palliative Care (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US30492110P | 2010-02-16 | 2010-02-16 | |
| PCT/IB2011/050548 WO2011101774A1 (en) | 2010-02-16 | 2011-02-09 | (r)-4-((4-((4-(tetrahydrofuran-3-yloxy)benzo[d]isoxazol-3-yloxy)methyl)piperidin-1-yl)methyl)tetrahydro-2h-pyran-4-ol, a partial agonist of 5-ht4 receptors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IN2012DN06631A true IN2012DN06631A (de) | 2015-10-23 |
Family
ID=43904611
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN6631DEN2012 IN2012DN06631A (de) | 2010-02-16 | 2011-02-09 |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US20120041026A1 (de) |
| EP (1) | EP2536713A1 (de) |
| JP (1) | JP2013519722A (de) |
| KR (1) | KR20120123089A (de) |
| CN (1) | CN102762554A (de) |
| AR (1) | AR080172A1 (de) |
| AU (1) | AU2011216950A1 (de) |
| CA (1) | CA2788656A1 (de) |
| IN (1) | IN2012DN06631A (de) |
| MX (1) | MX2012008721A (de) |
| SG (1) | SG183111A1 (de) |
| TW (1) | TW201141856A (de) |
| UY (1) | UY33225A (de) |
| WO (1) | WO2011101774A1 (de) |
| ZA (1) | ZA201206469B (de) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10583138B2 (en) | 2012-07-12 | 2020-03-10 | Glytech, Llc | Composition and method for treatment of depression and psychosis in humans |
| US9737531B2 (en) | 2012-07-12 | 2017-08-22 | Glytech, Llc | Composition and method for treatment of depression and psychosis in humans |
| MX350024B (es) * | 2011-05-18 | 2017-08-23 | Raqualia Pharma Inc | Formas polimorfas del ácido 4-{[4-({[4-(2,2,2-trifluoroetoxi)-1,2- benzisoxazol-3-il]oxi}metil)piperidin-1-il]metil}-tetrahidro-2h-p iran-4-carboxílico. |
| HK1208457A1 (en) * | 2012-11-21 | 2016-03-04 | 拉夸里亚创药株式会社 | Polymorph forms |
| US9790211B2 (en) | 2013-03-20 | 2017-10-17 | Suven Life Sciences Limited | 5-amino-quinoline-8-carboxamide derivatives as 5-HT4 receptor agonists |
| KR101824154B1 (ko) | 2013-12-16 | 2018-03-14 | 수벤 라이프 사이언시스 리미티드 | 5-ｈｔ４ 수용체 작용제로서 인다졸 화합물 |
| EP3145926B1 (de) * | 2014-05-20 | 2019-07-03 | RaQualia Pharma Inc. | Benzisoxazolderivatsalz |
| SI3265459T1 (sl) | 2015-02-13 | 2019-09-30 | Suven Life Sciences Limited, | Amidne spojine kot 5-HT4 receptor agonisti |
| CN117796401A (zh) * | 2023-12-25 | 2024-04-02 | 江苏万隆化学有限公司 | 一种含2-羟基-6-氟苯甲酸甲酯中间体抗菌剂的制备工艺 |
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| KR100224045B1 (ko) | 1991-02-27 | 1999-10-15 | 슈테펜엘.네스비트 | 엔엠디에이(nmda) 길항제 |
| US5750542A (en) * | 1993-09-28 | 1998-05-12 | Pfizer | Benzisoxazole and benzisothizole derivatives as cholinesterase inhibitors |
| NZ243065A (en) * | 1991-06-13 | 1995-07-26 | Lundbeck & Co As H | Piperidine derivatives and pharmaceutical compositions |
| AU690529B2 (en) * | 1992-11-23 | 1998-04-30 | Hoechst Marion Roussel, Inc. | Substituted 3-(aminoalkylamino)-1,2-benzisoxazoles and related compounds |
| US5889006A (en) | 1995-02-23 | 1999-03-30 | Schering Corporation | Muscarinic antagonists |
| IL117149A0 (en) | 1995-02-23 | 1996-06-18 | Schering Corp | Muscarinic antagonists |
| JP4108123B2 (ja) | 1995-09-29 | 2008-06-25 | グラクソスミスクライン・ソシエタ・ペル・アチオニ | Ｎｍｄａアンタゴニストとしてのテトラヒドロキノリン |
| IL126003A0 (en) | 1996-04-10 | 1999-04-11 | Hoechst Marion Roussel Inc | Spiro [cyclopent [b] indole-piperidines] and n-[phenyl-hydrazon intermediates for their preparation both being acetyl cholinesterase and mao inhibitors |
| CA2252039C (en) | 1996-04-12 | 2002-12-24 | Hoechst Marion Roussel, Inc. | Isatin derivatives as acetylcholinesterase inhibitors and analgesics |
| HUP9904167A3 (en) | 1996-07-01 | 2000-07-28 | Schering Corp | 1,4-disubstituted piperazine and piperidine derivatives, their use and pharmaceutical compositions containing the same |
| CN1155574C (zh) | 1996-08-15 | 2004-06-30 | 先灵公司 | 醚毒蕈碱性拮抗剂 |
| DE69734594T2 (de) | 1996-09-30 | 2006-07-06 | Aventis Pharmaceuticals Inc. | Nmda (n-methyl-d-aspartate) antagonists |
| CN1535682A (zh) | 1998-09-30 | 2004-10-13 | ����ҩƷ��ҵ��ʽ���� | 改善膀胱排泄能力的药物 |
| ATE380172T1 (de) | 2001-01-26 | 2007-12-15 | Btg Int Ltd | Benzylaminanalogen |
| JP2005506292A (ja) | 2001-03-08 | 2005-03-03 | エモリー ユニバーシティ | ｐＨに依存するＮＭＤＡレセプターアンタゴニスト |
| US7259157B2 (en) | 2001-04-03 | 2007-08-21 | Merck & Co., Inc. | N-substituted nonaryl-heterocyclo amidyl NMDA/NR2B Antagonists |
| SK287726B6 (en) | 2001-07-24 | 2011-07-06 | Richter Gedeon Vegyeszet | Carboxylic acid amide derivatives, their preparation, pharmaceutical compositions containing them and process for preparing pharmaceutical compositions |
| EP1648882B1 (de) | 2003-06-04 | 2008-08-06 | Merck & Co., Inc. | 3-fluoro-piperidine als nmda/nr2b antagonisten |
| GB0316094D0 (en) | 2003-07-09 | 2003-08-13 | Neuropharma Sa | Acetylcholinesterase dual inhibitors |
| LT2985039T (lt) * | 2004-03-03 | 2018-11-12 | Revance Therapeutics, Inc. | Botulino toksinų vietinis taikymas ir jų įvedimas per odą |
| HU227119B1 (en) | 2004-07-29 | 2010-07-28 | Richter Gedeon Nyrt | Indole and benzimidazole carboxylic acid amide derivatives and pharmaceutical compositions containing them |
| HU226977B1 (en) | 2004-07-29 | 2010-04-28 | Richter Gedeon Nyrt | Kynurenic acid amide derivatives, pharmaceutical compositions containing them and process for producing them |
| HUP0401522A2 (en) | 2004-07-29 | 2006-04-28 | Richter Gedeon Vegyeszet | New 4-benzylidene-piperidine derivatives, pharmaceutical compositions containing the same and process for their preparation |
| HUP0401523A3 (en) | 2004-07-29 | 2007-05-02 | Richter Gedeon Vegyeszet | Indole-2-carboxamide derivatives, pharmaceutical compositions containing them and process for producing them |
| HU227000B1 (en) | 2004-07-29 | 2010-04-28 | Richter Gedeon Nyrt | Nmda receptor antagonist benzoyl urea derivatives, and pharmaceutical compositions containing them |
| TW200621677A (en) | 2004-09-21 | 2006-07-01 | Astellas Pharma Inc | Cyclic amine derivative or salt thereof |
| CA2582640A1 (en) | 2004-10-15 | 2006-04-20 | Universidade Federal Do Rio De Janeiro-Ufrj | Piperidinic derivatives, pharmaceutic compositions containing the same and preparation processes |
| ES2523459T3 (es) * | 2005-02-25 | 2014-11-26 | Raqualia Pharma Inc | Derivados de benzisoxazol |
| US20090124600A1 (en) | 2005-04-19 | 2009-05-14 | Layton Mark E | N-Alkyl-Azacycloalkyl NMDA/NR2B Antagonists |
| JP2009503520A (ja) | 2005-07-29 | 2009-01-29 | リージェンツ オブ ザ ユニバーシティ オブ ミネソタ | ベータアミロイド受容体及びその使用 |
| JP2009531323A (ja) | 2006-03-20 | 2009-09-03 | カウンシル オブ サイエンティフィック アンド インダストリアル リサーチ | アセチルコリンエステラーゼ阻害剤として有用な薬剤組成物 |
| ES2288406B1 (es) | 2006-04-20 | 2008-12-16 | Universidad De Barcelona | Compuestos inhibidores de acetilcolinesterasa para el tratamiento de la enfermedad de alzheimer. |
| JP2010513395A (ja) | 2006-12-20 | 2010-04-30 | ソルベイ・フアーマシユーチカルズ・ベー・ブイ | カンナビノイド−ｃｂ１拮抗作用とアセチルコリンエステラーゼ阻害の組み合わせを示す化合物 |
| US7605265B2 (en) | 2007-01-22 | 2009-10-20 | Biotechnology Research Corporation Ltd. | Heterodimers and methods of using them |
| PL2345653T3 (pl) | 2007-05-01 | 2013-05-31 | Concert Pharmaceuticals Inc | Związki morfianu |
| CN101730706B (zh) | 2007-05-11 | 2015-04-15 | 生物科技研究有限公司 | 具有神经保护和增强记忆活性的受体拮抗剂 |
| EA201070077A1 (ru) | 2007-06-29 | 2010-08-30 | Эмори Юниверсити | Антагонисты nmda-рецепторов с нейропротективным действием |
| AP2010005217A0 (en) | 2007-09-12 | 2010-04-30 | Virginia Tech Intell Prop | Insecticidal carbamates exhibiting species-selective inhibition of acetyl cholinesterase (ACHE) |
| GB2470495B (en) | 2008-01-16 | 2012-12-26 | Biotechnology Res Corp Ltd | Oxazolidine derivatives as NMDA antagonists |
| EA014100B1 (ru) | 2008-02-21 | 2010-08-30 | Общество С Ограниченной Ответственностью "Валексфарм" | Производные 2,4-диаминопиридина, фармацевтическая композиция, лекарственное средство на их основе для лечения или предупреждения заболеваний и нарушений, вызванных гиперактивацией nmda-рецепторов и/или в качестве стимуляторов когнитивных функций и способ лечения |
| CN101440061B (zh) | 2008-04-08 | 2010-12-08 | 温州医学院 | 一类具有抑制乙酰胆碱酯酶活性的芳基吡啶酮类衍生物 |
| WO2009129181A1 (en) | 2008-04-14 | 2009-10-22 | Concert Pharmaceuticals Inc. | Propanediol-dicarbamate derivatives |
| MX2010012186A (es) | 2008-05-09 | 2011-02-22 | Univ Emory | Antagonistas del receptor nmda para el tratamiento de transtornos neuropsiquitricos. |
-
2011
- 2011-02-09 IN IN6631DEN2012 patent/IN2012DN06631A/en unknown
- 2011-02-09 CN CN2011800099647A patent/CN102762554A/zh active Pending
- 2011-02-09 JP JP2012553423A patent/JP2013519722A/ja not_active Withdrawn
- 2011-02-09 AU AU2011216950A patent/AU2011216950A1/en not_active Abandoned
- 2011-02-09 CA CA2788656A patent/CA2788656A1/en not_active Abandoned
- 2011-02-09 MX MX2012008721A patent/MX2012008721A/es not_active Application Discontinuation
- 2011-02-09 EP EP11710564A patent/EP2536713A1/de not_active Withdrawn
- 2011-02-09 KR KR1020127021310A patent/KR20120123089A/ko not_active Ceased
- 2011-02-09 WO PCT/IB2011/050548 patent/WO2011101774A1/en not_active Ceased
- 2011-02-09 SG SG2012053906A patent/SG183111A1/en unknown
- 2011-02-14 UY UY0001033225A patent/UY33225A/es not_active Application Discontinuation
- 2011-02-14 AR ARP110100443A patent/AR080172A1/es not_active Application Discontinuation
- 2011-02-15 TW TW100104942A patent/TW201141856A/zh unknown
- 2011-02-16 US US13/028,368 patent/US20120041026A1/en not_active Abandoned
-
2012
- 2012-08-28 ZA ZA2012/06469A patent/ZA201206469B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US20120041026A1 (en) | 2012-02-16 |
| CA2788656A1 (en) | 2011-08-25 |
| TW201141856A (en) | 2011-12-01 |
| ZA201206469B (en) | 2013-05-29 |
| AR080172A1 (es) | 2012-03-21 |
| UY33225A (es) | 2011-09-30 |
| MX2012008721A (es) | 2012-08-17 |
| WO2011101774A1 (en) | 2011-08-25 |
| KR20120123089A (ko) | 2012-11-07 |
| CN102762554A (zh) | 2012-10-31 |
| SG183111A1 (en) | 2012-09-27 |
| EP2536713A1 (de) | 2012-12-26 |
| JP2013519722A (ja) | 2013-05-30 |
| AU2011216950A1 (en) | 2012-08-23 |
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