IN2013CN00536A - - Google Patents
Info
- Publication number
- IN2013CN00536A IN2013CN00536A IN536CHN2013A IN2013CN00536A IN 2013CN00536 A IN2013CN00536 A IN 2013CN00536A IN 536CHN2013 A IN536CHN2013 A IN 536CHN2013A IN 2013CN00536 A IN2013CN00536 A IN 2013CN00536A
- Authority
- IN
- India
- Prior art keywords
- protein
- hpv52
- truncated
- vlp
- infection
- Prior art date
Links
- 108700042300 human papillomavirus type 52 L1 Proteins 0.000 abstract 3
- 108090000623 proteins and genes Proteins 0.000 abstract 3
- 102000004169 proteins and genes Human genes 0.000 abstract 3
- 241000701806 Human papillomavirus Species 0.000 abstract 2
- 208000015181 infectious disease Diseases 0.000 abstract 2
- 206010008342 Cervix carcinoma Diseases 0.000 abstract 1
- 108091026890 Coding region Proteins 0.000 abstract 1
- 241000588724 Escherichia coli Species 0.000 abstract 1
- 208000006105 Uterine Cervical Neoplasms Diseases 0.000 abstract 1
- 241000700605 Viruses Species 0.000 abstract 1
- 150000001413 amino acids Chemical class 0.000 abstract 1
- 201000010881 cervical cancer Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 239000002245 particle Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
- C07K14/01—DNA viruses
- C07K14/025—Papovaviridae, e.g. papillomavirus, polyomavirus, SV40, BK virus, JC virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5258—Virus-like particles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/58—Medicinal preparations containing antigens or antibodies raising an immune response against a target which is not the antigen used for immunisation
- A61K2039/585—Medicinal preparations containing antigens or antibodies raising an immune response against a target which is not the antigen used for immunisation wherein the target is cancer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/80—Vaccine for a specifically defined cancer
- A61K2039/892—Reproductive system [uterus, ovaries, cervix, testes]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/20011—Papillomaviridae
- C12N2710/20022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/20011—Papillomaviridae
- C12N2710/20023—Virus like particles [VLP]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/20011—Papillomaviridae
- C12N2710/20034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/20011—Papillomaviridae
- C12N2710/20051—Methods of production or purification of viral material
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Virology (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Engineering & Computer Science (AREA)
- Gastroenterology & Hepatology (AREA)
- Biophysics (AREA)
- Oncology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201010216189 | 2010-07-02 | ||
| PCT/CN2011/076763 WO2012000454A1 (zh) | 2010-07-02 | 2011-07-01 | 截短的人乳头瘤病毒52型l1蛋白 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IN2013CN00536A true IN2013CN00536A (pt) | 2015-07-03 |
Family
ID=45050553
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN536CHN2013 IN2013CN00536A (pt) | 2010-07-02 | 2011-07-01 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US9499591B2 (pt) |
| EP (1) | EP2589604B1 (pt) |
| CN (1) | CN102268076B (pt) |
| DK (1) | DK2589604T3 (pt) |
| IN (1) | IN2013CN00536A (pt) |
| WO (1) | WO2012000454A1 (pt) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103044531B (zh) * | 2012-09-29 | 2014-07-30 | 重庆原伦生物科技有限公司 | 耐甲氧西林金黄色葡萄球菌(mrsa)疫苗重组蛋白抗原hi2的纯化方法 |
| CN106701796B (zh) * | 2015-08-12 | 2021-11-16 | 北京康乐卫士生物技术股份有限公司 | 52型重组人乳头瘤病毒病毒样颗粒及其制备方法 |
| CN105985934A (zh) * | 2015-08-18 | 2016-10-05 | 北京康乐卫士生物技术股份有限公司 | 一种二价、三价或多价hpv假病毒及其应用 |
| EP3385273A4 (en) * | 2015-12-04 | 2019-08-07 | Xiamen University | MUTANT OF HUMAN PAPILLOMAIRUS TYPE 58 L1 PROTEIN |
| CN106831959B (zh) * | 2015-12-04 | 2019-11-05 | 厦门大学 | 一种人乳头瘤病毒33型l1蛋白的突变体 |
| CN107557347B (zh) * | 2016-06-30 | 2022-03-29 | 中国科学院上海巴斯德研究所 | 肠道病毒71型的新型病毒样颗粒、其制备方法及应用 |
| WO2021013071A1 (zh) | 2019-07-19 | 2021-01-28 | 神州细胞工程有限公司 | 人乳头瘤病毒多价免疫原性组合物 |
| CN114174319B (zh) * | 2019-07-19 | 2024-05-14 | 神州细胞工程有限公司 | 嵌合的人乳头瘤病毒52型l1蛋白 |
| CN114539365B (zh) * | 2020-11-26 | 2023-12-01 | 中国医学科学院基础医学研究所 | 一种改造的人乳头瘤病毒52型l1蛋白及其用途 |
| US20250281594A1 (en) * | 2024-03-11 | 2025-09-11 | Sk Bioscience Co., Ltd. | Truncated recombinant l1 protein of human papillomavirus |
| CN119684471B (zh) * | 2024-12-10 | 2025-10-10 | 昆明理工大学 | 一种52型人乳头瘤病毒l1蛋白的重组蛋白及其应用 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2000054730A2 (en) * | 1999-03-18 | 2000-09-21 | The President & Fellows Of Harvard College | Compositions preparations and uses of human papillomavirus l1 protein |
| CN1293093C (zh) | 2002-08-30 | 2007-01-03 | 马润林 | 乳头瘤病毒衣壳蛋白的原核制备和应用 |
| ATE466022T1 (de) * | 2004-03-24 | 2010-05-15 | Merck Sharp & Dohme | Optimierte expression von hpv-52-l1 in hefe |
| CN101153280B (zh) | 2006-09-29 | 2015-08-19 | 厦门大学 | 从原核生物中纯化人乳头瘤病毒晚期蛋白l1的方法 |
| EP2147926B1 (en) | 2007-04-29 | 2016-08-24 | Beijing Wantai Biological Pharmacy Enterprise Co., Ltd. | Truncated human papillomavirus type 18 l1 proteins |
| EP2154147B1 (en) | 2007-04-29 | 2015-10-07 | Beijing Wantai Biological Pharmacy Enterprise Co., Ltd. | A truncated l1 protein of human papillomavirus 16 |
| US9533035B2 (en) | 2007-05-29 | 2017-01-03 | Xiamen University | Truncated L1 protein of human papillomavirus type 11 |
| EP2154149B1 (en) | 2007-05-29 | 2019-07-10 | Xiamen University | A truncated l1 protein of human papillomavirus 6 |
-
2011
- 2011-07-01 CN CN201110182799.7A patent/CN102268076B/zh active Active
- 2011-07-01 IN IN536CHN2013 patent/IN2013CN00536A/en unknown
- 2011-07-01 WO PCT/CN2011/076763 patent/WO2012000454A1/zh not_active Ceased
- 2011-07-01 EP EP11800199.9A patent/EP2589604B1/en active Active
- 2011-07-01 US US13/807,858 patent/US9499591B2/en active Active
- 2011-07-01 DK DK11800199.9T patent/DK2589604T3/en active
Also Published As
| Publication number | Publication date |
|---|---|
| WO2012000454A1 (zh) | 2012-01-05 |
| US9499591B2 (en) | 2016-11-22 |
| EP2589604A1 (en) | 2013-05-08 |
| EP2589604B1 (en) | 2016-10-05 |
| DK2589604T3 (en) | 2017-01-16 |
| US20130230548A1 (en) | 2013-09-05 |
| CN102268076A (zh) | 2011-12-07 |
| CN102268076B (zh) | 2017-04-26 |
| BR112013000031A2 (pt) | 2016-05-10 |
| EP2589604A4 (en) | 2013-12-18 |
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