IN2013CN01326A - - Google Patents
Info
- Publication number
- IN2013CN01326A IN2013CN01326A IN1326CHN2013A IN2013CN01326A IN 2013CN01326 A IN2013CN01326 A IN 2013CN01326A IN 1326CHN2013 A IN1326CHN2013 A IN 1326CHN2013A IN 2013CN01326 A IN2013CN01326 A IN 2013CN01326A
- Authority
- IN
- India
- Prior art keywords
- group
- combination
- trifluoromethyl
- bis
- phenyl
- Prior art date
Links
- QPFMBZIOSGYJDE-UHFFFAOYSA-N 1,1,2,2-tetrachloroethane Chemical compound ClC(Cl)C(Cl)Cl QPFMBZIOSGYJDE-UHFFFAOYSA-N 0.000 abstract 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 2
- CPELXLSAUQHCOX-UHFFFAOYSA-N Hydrogen bromide Chemical compound Br CPELXLSAUQHCOX-UHFFFAOYSA-N 0.000 abstract 2
- PCLIMKBDDGJMGD-UHFFFAOYSA-N N-bromosuccinimide Chemical compound BrN1C(=O)CCC1=O PCLIMKBDDGJMGD-UHFFFAOYSA-N 0.000 abstract 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
- OTMSDBZUPAUEDD-UHFFFAOYSA-N Ethane Chemical compound CC OTMSDBZUPAUEDD-UHFFFAOYSA-N 0.000 abstract 1
- UCKMPCXJQFINFW-UHFFFAOYSA-N Sulphide Chemical compound [S-2] UCKMPCXJQFINFW-UHFFFAOYSA-N 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 125000004104 aryloxy group Chemical group 0.000 abstract 1
- 125000001246 bromo group Chemical group Br* 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 125000000950 dibromo group Chemical group Br* 0.000 abstract 1
- 229910000042 hydrogen bromide Inorganic materials 0.000 abstract 1
- 230000003287 optical effect Effects 0.000 abstract 1
- 150000002903 organophosphorus compounds Chemical class 0.000 abstract 1
- 229910052698 phosphorus Inorganic materials 0.000 abstract 1
- 239000011574 phosphorus Substances 0.000 abstract 1
- -1 phosphorus halide Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C17/00—Preparation of halogenated hydrocarbons
- C07C17/013—Preparation of halogenated hydrocarbons by addition of halogens
- C07C17/04—Preparation of halogenated hydrocarbons by addition of halogens to unsaturated halogenated hydrocarbons
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B53/00—Asymmetric syntheses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C17/00—Preparation of halogenated hydrocarbons
- C07C17/093—Preparation of halogenated hydrocarbons by replacement by halogens
- C07C17/16—Preparation of halogenated hydrocarbons by replacement by halogens of hydroxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C22/00—Cyclic compounds containing halogen atoms bound to an acyclic carbon atom
- C07C22/02—Cyclic compounds containing halogen atoms bound to an acyclic carbon atom having unsaturation in the rings
- C07C22/04—Cyclic compounds containing halogen atoms bound to an acyclic carbon atom having unsaturation in the rings containing six-membered aromatic rings
- C07C22/08—Cyclic compounds containing halogen atoms bound to an acyclic carbon atom having unsaturation in the rings containing six-membered aromatic rings containing fluorine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2010164725 | 2010-07-22 | ||
| JP2010164726 | 2010-07-22 | ||
| PCT/JP2011/066512 WO2012011516A1 (ja) | 2010-07-22 | 2011-07-21 | 光学活性１－ブロモ－１－［３，５－ビス（トリフルオロメチル）フェニル］エタンの製造方法 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IN2013CN01326A true IN2013CN01326A (de) | 2015-04-24 |
Family
ID=45496934
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN1326CHN2013 IN2013CN01326A (de) | 2010-07-22 | 2011-07-21 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US9272966B2 (de) |
| EP (1) | EP2597079A4 (de) |
| JP (1) | JP5793143B2 (de) |
| CN (2) | CN105837401A (de) |
| HK (1) | HK1223908A1 (de) |
| IN (1) | IN2013CN01326A (de) |
| WO (1) | WO2012011516A1 (de) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104628584B (zh) * | 2013-11-08 | 2017-03-08 | 广州朗圣药业有限公司 | 一种适合工业化的高纯度达泊西汀的制备方法 |
| CN114105796B (zh) * | 2021-12-11 | 2023-11-28 | 上海化工研究院有限公司 | 一种稳定性同位素氘标记异亮氨酸的合成方法 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6750344B1 (en) * | 1997-09-05 | 2004-06-15 | Isis Pharmaceuticals, Inc. | Amine compounds and combinatorial libraries comprising same |
| JP3938651B2 (ja) | 2000-04-13 | 2007-06-27 | セントラル硝子株式会社 | 光学活性α−メチル−ビス−３、５−（トリフルオロメチル）ベンジルアミンの製造方法 |
| EP1942734A4 (de) | 2005-10-06 | 2010-04-07 | Reddys Lab Ltd Dr | Herstellung von aprepitant |
| US7790737B2 (en) * | 2007-03-13 | 2010-09-07 | Kowa Company, Ltd. | Substituted pyrimidine compounds and their utility as CETP inhibitors |
| CA2683534C (en) | 2007-04-13 | 2015-02-24 | Kowa Company, Ltd. | Novel pyrimidine compound having dibenzylamine structure and medicament comprising the same |
| CN101412711A (zh) * | 2007-10-15 | 2009-04-22 | 上海恒瑞医药有限公司 | 氨基甲酸酯类衍生物及其在医药上的应用 |
| MX2010006243A (es) | 2007-12-06 | 2010-08-31 | Schering Corp | Moduladores de gamma secretasa. |
| JP5319457B2 (ja) * | 2008-08-25 | 2013-10-16 | 興和株式会社 | 新規なジベンジルアミン構造を有するピリミジン化合物及びこれを含有する医薬 |
| KR20130111512A (ko) * | 2010-06-04 | 2013-10-10 | 코와 가부시키가이샤 | 광학 활성 디벤질아민 유도체 및 그의 제조 방법 |
| JPWO2012046681A1 (ja) | 2010-10-04 | 2014-02-24 | 興和株式会社 | 脂質代謝関連ｍＲＮＡの発現抑制剤 |
-
2011
- 2011-07-21 IN IN1326CHN2013 patent/IN2013CN01326A/en unknown
- 2011-07-21 EP EP11809686.6A patent/EP2597079A4/de not_active Withdrawn
- 2011-07-21 JP JP2012525419A patent/JP5793143B2/ja not_active Expired - Fee Related
- 2011-07-21 CN CN201610205007.6A patent/CN105837401A/zh active Pending
- 2011-07-21 US US13/811,651 patent/US9272966B2/en not_active Expired - Fee Related
- 2011-07-21 WO PCT/JP2011/066512 patent/WO2012011516A1/ja not_active Ceased
- 2011-07-21 CN CN2011800357009A patent/CN102985395A/zh active Pending
-
2016
- 2016-09-23 HK HK16111176.5A patent/HK1223908A1/zh unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP2597079A1 (de) | 2013-05-29 |
| WO2012011516A1 (ja) | 2012-01-26 |
| EP2597079A4 (de) | 2015-11-11 |
| JP5793143B2 (ja) | 2015-10-14 |
| JPWO2012011516A1 (ja) | 2013-09-09 |
| HK1223908A1 (zh) | 2017-08-11 |
| CN102985395A (zh) | 2013-03-20 |
| US20130190540A1 (en) | 2013-07-25 |
| US9272966B2 (en) | 2016-03-01 |
| CN105837401A (zh) | 2016-08-10 |
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