IN2013MN01188A - - Google Patents
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- Publication number
- IN2013MN01188A IN2013MN01188A IN1188MUN2013A IN2013MN01188A IN 2013MN01188 A IN2013MN01188 A IN 2013MN01188A IN 1188MUN2013 A IN1188MUN2013 A IN 1188MUN2013A IN 2013MN01188 A IN2013MN01188 A IN 2013MN01188A
- Authority
- IN
- India
- Prior art keywords
- lutetium
- radiotherapy
- tumor
- novel
- directed
- Prior art date
Links
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- DNDCVAGJPBKION-DOPDSADYSA-N bombesin Chemical class C([C@@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(N)=O)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](CC=1NC2=CC=CC=C2C=1)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H]1NC(=O)CC1)C(C)C)C1=CN=CN1 DNDCVAGJPBKION-DOPDSADYSA-N 0.000 abstract 1
- OHSVLFRHMCKCQY-NJFSPNSNSA-N lutetium-177 Chemical compound [177Lu] OHSVLFRHMCKCQY-NJFSPNSNSA-N 0.000 abstract 1
- 238000001959 radiotherapy Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A61K51/088—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/13—Labelling of peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Optics & Photonics (AREA)
- Physics & Mathematics (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Endocrinology (AREA)
- Zoology (AREA)
- Reproductive Health (AREA)
- Pulmonology (AREA)
- Toxicology (AREA)
- Analytical Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Oncology (AREA)
- Urology & Nephrology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Radiation-Therapy Devices (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The invention is directed to novel Lutetium 177 labeled bombesin analogs for treatment of tumor by radiotherapy.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP10075743 | 2010-11-22 | ||
| PCT/EP2011/070553 WO2012069410A1 (en) | 2010-11-22 | 2011-11-21 | 177lutetium-labeled bombesin analogs for radiotherapy |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IN2013MN01188A true IN2013MN01188A (en) | 2015-07-10 |
Family
ID=45001762
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN1188MUN2013 IN2013MN01188A (en) | 2010-11-22 | 2011-11-21 |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US20140023585A1 (en) |
| EP (1) | EP2643024A1 (en) |
| JP (1) | JP2014500262A (en) |
| KR (1) | KR20140053819A (en) |
| CN (1) | CN103476434A (en) |
| AU (1) | AU2011333948A1 (en) |
| BR (1) | BR112013012503A2 (en) |
| CA (1) | CA2818694A1 (en) |
| EA (1) | EA026443B1 (en) |
| IL (1) | IL226498A0 (en) |
| IN (1) | IN2013MN01188A (en) |
| MX (1) | MX2013005697A (en) |
| NZ (1) | NZ610740A (en) |
| PH (1) | PH12013501018A1 (en) |
| SG (1) | SG190371A1 (en) |
| WO (1) | WO2012069410A1 (en) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2100900A1 (en) * | 2008-03-07 | 2009-09-16 | Universitätsspital Basel | Bombesin analog peptide antagonist conjugates |
| ES2745635T3 (en) | 2012-09-25 | 2020-03-03 | Advanced Accelerator Applications Usa Inc | GRPR antagonists for the detection, diagnosis and treatment of GRPR positive cancer |
| CN106039327A (en) * | 2016-06-14 | 2016-10-26 | 宁波益格爱生物科技有限公司 | GRPR targeted molecular probe and preparation method thereof |
| US20190358351A1 (en) * | 2016-11-17 | 2019-11-28 | Minerva Imaging Aps | 177-lu labeled active site inhibited factor vii |
| CA3153267A1 (en) * | 2019-12-19 | 2021-06-24 | Hans-Jurgen Wester | Modified grpr antagonist peptides for imaging and therapy of cancer |
| EP4282439A1 (en) * | 2022-05-23 | 2023-11-29 | Erasmus University Rotterdam Medical Center | Radioisotope labeled sstr2-agonists with linkers |
| CN117919452A (en) * | 2023-03-09 | 2024-04-26 | 中国科学院宁波材料技术与工程研究所 | Subcellular organelle active targeting imaging probe and preparation method thereof |
| CN121793988A (en) | 2023-09-13 | 2026-04-03 | 东丽株式会社 | Pharmaceutical composition for the treatment, prevention and/or diagnosis of cancer |
| CN121752302A (en) * | 2023-12-05 | 2026-03-27 | 烟台蓝纳成生物技术股份有限公司 | A heterodimeric radionuclide conjugate drug, its preparation and application |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2100900A1 (en) * | 2008-03-07 | 2009-09-16 | Universitätsspital Basel | Bombesin analog peptide antagonist conjugates |
-
2011
- 2011-11-21 IN IN1188MUN2013 patent/IN2013MN01188A/en unknown
- 2011-11-21 BR BR112013012503A patent/BR112013012503A2/en active Search and Examination
- 2011-11-21 KR KR1020137016242A patent/KR20140053819A/en not_active Ceased
- 2011-11-21 CA CA2818694A patent/CA2818694A1/en not_active Abandoned
- 2011-11-21 WO PCT/EP2011/070553 patent/WO2012069410A1/en not_active Ceased
- 2011-11-21 PH PH1/2013/501018A patent/PH12013501018A1/en unknown
- 2011-11-21 EP EP11785422.4A patent/EP2643024A1/en not_active Withdrawn
- 2011-11-21 JP JP2013540310A patent/JP2014500262A/en active Pending
- 2011-11-21 CN CN2011800561585A patent/CN103476434A/en active Pending
- 2011-11-21 US US13/988,629 patent/US20140023585A1/en not_active Abandoned
- 2011-11-21 EA EA201300611A patent/EA026443B1/en not_active IP Right Cessation
- 2011-11-21 SG SG2013039508A patent/SG190371A1/en unknown
- 2011-11-21 NZ NZ610740A patent/NZ610740A/en not_active IP Right Cessation
- 2011-11-21 MX MX2013005697A patent/MX2013005697A/en not_active Application Discontinuation
- 2011-11-21 AU AU2011333948A patent/AU2011333948A1/en not_active Abandoned
-
2013
- 2013-05-21 IL IL226498A patent/IL226498A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US20140023585A1 (en) | 2014-01-23 |
| CN103476434A (en) | 2013-12-25 |
| WO2012069410A1 (en) | 2012-05-31 |
| SG190371A1 (en) | 2013-06-28 |
| EP2643024A1 (en) | 2013-10-02 |
| MX2013005697A (en) | 2014-08-01 |
| PH12013501018A1 (en) | 2017-08-23 |
| EA201300611A1 (en) | 2014-04-30 |
| AU2011333948A1 (en) | 2013-06-06 |
| JP2014500262A (en) | 2014-01-09 |
| IL226498A0 (en) | 2013-07-31 |
| KR20140053819A (en) | 2014-05-08 |
| BR112013012503A2 (en) | 2016-11-08 |
| NZ610740A (en) | 2015-08-28 |
| EA026443B1 (en) | 2017-04-28 |
| CA2818694A1 (en) | 2012-05-31 |
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