IN2014CN03680A - - Google Patents

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Publication number
IN2014CN03680A
IN2014CN03680A IN3680CHN2014A IN2014CN03680A IN 2014CN03680 A IN2014CN03680 A IN 2014CN03680A IN 3680CHN2014 A IN3680CHN2014 A IN 3680CHN2014A IN 2014CN03680 A IN2014CN03680 A IN 2014CN03680A
Authority
IN
India
Prior art keywords
droplet
aqueous
drop
amphipathic molecules
encapsulates
Prior art date
Application number
Other languages
English (en)
Inventor
John Hagan Pryce Bayley
Andrew Heron
Gabriel Villar
Original Assignee
Isis Innovation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Isis Innovation filed Critical Isis Innovation
Publication of IN2014CN03680A publication Critical patent/IN2014CN03680A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/113—Multiple emulsions, e.g. oil-in-water-in-oil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/075—Ethers or acetals
    • A61K31/085—Ethers or acetals having an ether linkage to aromatic ring nuclear carbon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/0002—General or multifunctional contrast agents, e.g. chelated agents
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02—Making microcapsules or microballoons
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02—Making microcapsules or microballoons
    • B01J13/025—Applications of microcapsules not provided for in other subclasses
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B67/00—Influencing the physical, e.g. the dyeing or printing properties of dyestuffs without chemical reactions, e.g. by treating with solvents grinding or grinding assistants, coating of pigments or dyes; Process features in the making of dyestuff preparations; Dyestuff preparations of a special physical nature, e.g. tablets, films
    • C09B67/0097—Dye preparations of special physical nature; Tablets, films, extrusion, microcapsules, sheets, pads, bags with dyes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2984—Microcapsule with fluid core [includes liposome]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Cosmetics (AREA)
IN3680CHN2014 2011-11-03 2012-11-02 IN2014CN03680A (th)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB1119032.9A GB201119032D0 (en) 2011-11-03 2011-11-03 Multisomes: encapsulated droplet networks
US201261592062P 2012-01-30 2012-01-30
PCT/GB2012/052736 WO2013064837A1 (en) 2011-11-03 2012-11-02 Multisomes: encapsulated droplet networks

Publications (1)

Publication Number Publication Date
IN2014CN03680A true IN2014CN03680A (th) 2015-09-25

Family

ID=45375781

Family Applications (1)

Application Number Title Priority Date Filing Date
IN3680CHN2014 IN2014CN03680A (th) 2011-11-03 2012-11-02

Country Status (11)

Country Link
US (3) US10548852B2 (th)
EP (1) EP2773451A1 (th)
JP (1) JP6234371B2 (th)
KR (1) KR102038450B1 (th)
CN (1) CN104053497B (th)
AU (1) AU2012330894B2 (th)
BR (1) BR112014010811B1 (th)
CA (1) CA2853966C (th)
GB (1) GB201119032D0 (th)
IN (1) IN2014CN03680A (th)
WO (1) WO2013064837A1 (th)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201119032D0 (en) 2011-11-03 2011-12-14 Isis Innovation Multisomes: encapsulated droplet networks
GB201219201D0 (en) 2012-10-25 2012-12-12 Isis Innovation Hydrogel network
GB201219196D0 (en) 2012-10-25 2012-12-12 Isis Innovation Droplet assembly method
KR102449271B1 (ko) 2012-12-07 2022-09-29 옥스포드 유니버시티 이노베이션 리미티드 3d 프린팅에 의한 비말 어셈블리
WO2014093714A1 (en) * 2012-12-14 2014-06-19 Bio-Rad Laboratories, Inc. Methods and compositions for using oils for analysis and detection of molecules
FR3000688B1 (fr) * 2013-01-08 2016-09-30 Centre Nat De La Rech Scient - Cnrs - Procede pour activer une reaction chimique, melange activable par ce procede et dispostiif pour la mise en oeuvre de ce procede
EP2970668B1 (en) 2013-03-15 2020-07-01 Bio-rad Laboratories, Inc. Silicone surfactants for emulsion assays
HK1220390A1 (zh) * 2013-08-29 2017-05-05 Teva Pharmaceutical Industries Ltd. 包括恩曲他滨，替诺福韦，达芦那韦和利托那韦的单位剂型以及包含达芦那韦和利托那韦的单体片剂
CA2942877A1 (en) * 2014-04-08 2015-10-15 Nitzan SHAHAR Unit dosage form comprising emtricitabine, tenofovir, darunavir and ritonavir
ES2789000T3 (es) 2014-10-10 2020-10-23 Quantapore Inc Análisis de polinucleótidos basado en nanoporos con marcadores fluorescentes que se inactivan mutuamente
US10641764B2 (en) 2015-07-02 2020-05-05 The University Of Massachusetts Membrane and droplet-interface bilayer systems and methods
CN108473933A (zh) 2015-12-08 2018-08-31 昆塔波尔公司 使核酸移位通过纳米孔的方法
WO2017149297A1 (en) * 2016-03-01 2017-09-08 Oxford University Innovation Limited Phase transfer of a cargo laden scaffold
GB201603591D0 (en) * 2016-03-01 2016-04-13 Isis Innovation Improved promotors and compositions
GB201615741D0 (en) 2016-09-15 2016-11-02 Univ College Cardiff Consultants Ltd Artificial cells
GB2561157A (en) * 2017-03-27 2018-10-10 Univ Oxford Innovation Ltd Compartmentalised gel matrix and method of production
CN110961055B (zh) * 2019-12-06 2021-01-05 锦州医科大学 离子液体聚合微球及其制备方法和应用
AU2021241095A1 (en) * 2020-03-26 2022-10-27 Kyushu University, National University Corporation Ionic liquid, solvent, preparation, and transdermally absorbable agent
CN112588218B (zh) * 2020-12-11 2021-09-21 中国科学院力学研究所 一种实现液滴快速自发旋转的方法
CN114250190A (zh) * 2021-12-22 2022-03-29 北京京东方技术开发有限公司 封装细胞及其制备方法

Family Cites Families (82)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4812856A (en) 1987-10-30 1989-03-14 Microfab Technologies, Inc. Method and apparatus for dispensing a fluid with dispersed particles therein
US5104736A (en) 1988-03-03 1992-04-14 Micro-Pak, Inc. Reinforced paucilamellar lipid vesicles
US4934564A (en) 1989-03-23 1990-06-19 Eastman Kodak Company Drop jet metering method and system
US5858399A (en) 1992-04-09 1999-01-12 Northwestern University Acoustically reflective liposomes and methods to make and use the same
US5464629A (en) 1993-11-16 1995-11-07 Georgetown University Method of forming hydrogel particles having a controlled size using liposomes
US6531156B1 (en) 1994-04-15 2003-03-11 Temple University Aqueous solven encapsulation method, apparatus and microcapsules
DE4438232A1 (de) 1994-10-26 1996-05-02 Guenter Prof Dr Fuhr Kryokonservierung und Tieftemperaturbearbeitung von biologischen Zellen
CA2564120C (en) 1997-01-31 2010-04-13 Skyepharma Inc. Method for utilizing neutral lipids to modify in vivo release from multivesicular liposomes
US5891467A (en) 1997-01-31 1999-04-06 Depotech Corporation Method for utilizing neutral lipids to modify in vivo release from multivesicular liposomes
US6106858A (en) 1997-09-08 2000-08-22 Skyepharma, Inc. Modulation of drug loading in multivescular liposomes
US7470547B2 (en) 2003-07-31 2008-12-30 Biodot, Inc. Methods and systems for dispensing sub-microfluidic drops
US6461812B2 (en) 1998-09-09 2002-10-08 Agilent Technologies, Inc. Method and multiple reservoir apparatus for fabrication of biomolecular arrays
BR9915963B1 (pt) * 1998-12-05 2012-07-24 emulsço àleo em Água cosmÉtica ou para o cuidado pessoal na forma de leite ou creme, emulsço de mistura seca, mistura seca, e, uso de uma combinaÇço de polissacarÍdeo, de um polissacarÍdeo de xantano e de um polissacarÍdeo de poliglucomanano.
EP1099484B1 (en) 1999-11-11 2006-06-07 The Provost, Fellows And Scholars Of The College Of The Holy And Undivided Trinity Of Queen Elizabeth Near Dublin A dispensing method and assembly for liquid droplets
US20030048341A1 (en) 2000-09-25 2003-03-13 Mutz Mitchell W. High-throughput biomolecular crystallization and biomolecular crystal screening
US20020106308A1 (en) 2001-02-02 2002-08-08 Zweifel Ronald A. Microdrop dispensing apparatus
US20030119193A1 (en) 2001-04-25 2003-06-26 Robert Hess System and method for high throughput screening of droplets
US7943067B2 (en) 2001-08-16 2011-05-17 Polytechnic Institute Of New York University Nanogels and their production using liposomes as reactors
US6995024B2 (en) 2001-08-27 2006-02-07 Sri International Method and apparatus for electrostatic dispensing of microdroplets
US6962747B1 (en) 2001-10-23 2005-11-08 Sandia Corporation Self-assembled lipid bilayer materials
US6945638B2 (en) 2001-10-29 2005-09-20 Therics, Inc. Method and system for controlling the temperature of a dispensed liquid
US6960298B2 (en) 2001-12-10 2005-11-01 Nanogen, Inc. Mesoporous permeation layers for use on active electronic matrix devices
FR2846041B1 (fr) * 2002-10-18 2006-06-09 Peugeot Citroen Automobiles Sa Moteur a combustion interne a suralimentation et bougie a prechambre, procede d'allumage et application
US7160614B2 (en) 2002-11-01 2007-01-09 Sony Corporation Crystalline superfine particles, complex material, method of manufacturing crystalline superfine particles, inverted micelles, inverted micelles enveloping precursor superfine particles, inverted micelles enveloping crystalline superfine particles, and precursor superfine particles
EP1622574A4 (en) * 2003-04-25 2006-10-18 Medimmune Vaccines Inc EXPRESSION SYSTEMS OF RECOMBINANT PARAINFLUENZA VIRUSES AND VACCINES COMPRISING HETEROLOGOUS ANTIGENS DERIVED FROM METAPNEUMOVIRUS
US7914714B2 (en) 2003-05-14 2011-03-29 The Regents Of The University Of Colorado Methods and apparatus using electrostatic atomization to form liquid vesicles
US7051654B2 (en) 2003-05-30 2006-05-30 Clemson University Ink-jet printing of viable cells
US7217410B2 (en) 2003-06-17 2007-05-15 The Board Of Trustees Of The Universtiy Of Illinois Surface modified protein microparticles
JPWO2005053643A1 (ja) 2003-12-01 2007-06-28 三菱ウェルファーマ株式会社 リポソーム
WO2005061536A1 (en) * 2003-12-16 2005-07-07 Aventis Pharmaceuticals Inc. Secreted neural apoptosis inhibiting proteins
US20080226500A1 (en) 2004-01-15 2008-09-18 Mitsuhiro Shikida Chemical Analytic Apparatus and Chemical Analytic Method
WO2006096571A2 (en) 2005-03-04 2006-09-14 President And Fellows Of Harvard College Method and apparatus for forming multiple emulsions
US20060210443A1 (en) 2005-03-14 2006-09-21 Stearns Richard G Avoidance of bouncing and splashing in droplet-based fluid transport
GB0505971D0 (en) 2005-03-23 2005-04-27 Isis Innovation Delivery of molecules to a lipid bilayer
US8076090B2 (en) * 2005-04-05 2011-12-13 Corning Incorporated Label free biosensors and cells
JP2007046595A (ja) 2005-07-15 2007-02-22 Daikin Ind Ltd 回転式圧縮機
JP5114702B2 (ja) 2005-07-29 2013-01-09 国立大学法人 東京大学 両親媒性単分子膜の接触による二分子膜の形成方法およびその装置
US20070148697A1 (en) 2005-12-27 2007-06-28 Boston Scientific Scimed, Inc. Methods and system for high throughput screening of polymer materials for medical devices
JP2009526970A (ja) 2006-02-13 2009-07-23 エージェンシー フォー サイエンス，テクノロジー アンド リサーチ 生物学的試料または化学的試料の処理方法
WO2007101174A2 (en) 2006-02-27 2007-09-07 Arizona Board Of Regents For And On Behalf Of Arizona State University Digital magnetofluidic devices and methods
US8492168B2 (en) 2006-04-18 2013-07-23 Advanced Liquid Logic Inc. Droplet-based affinity assays
US7439014B2 (en) 2006-04-18 2008-10-21 Advanced Liquid Logic, Inc. Droplet-based surface modification and washing
US7901947B2 (en) 2006-04-18 2011-03-08 Advanced Liquid Logic, Inc. Droplet-based particle sorting
WO2007124023A2 (en) 2006-04-21 2007-11-01 Wake Forest University Health Sciences Ink-jet printing of tissues
US20070293449A1 (en) * 2006-06-20 2007-12-20 Nastech Pharmaceutical Company Inc. Compositions and methods for delivery of double-stranded rna
KR100817086B1 (ko) 2006-07-21 2008-03-26 삼성전자주식회사 비전도성 모세관 노즐을 구비한 전하집중 방식 액적디스펜싱 장치
GB0614835D0 (en) 2006-07-26 2006-09-06 Isis Innovation Formation of bilayers of amphipathic molecules
US9364016B2 (en) 2006-09-19 2016-06-14 The Product Makers (Australia) Pty Ltd Extracts derived from sugar cane and a process for their manufacture
EP1920765A1 (en) 2006-11-07 2008-05-14 Medigene AG Liposome preparation by single-pass process
EP2136786B8 (en) 2007-03-28 2012-11-14 President and Fellows of Harvard College Apparatus for forming droplets
GB0716264D0 (en) 2007-08-21 2007-09-26 Isis Innovation Bilayers
US8293339B2 (en) 2007-09-17 2012-10-23 Sri International, Inc. Droplet bilayers
US9468607B2 (en) 2007-10-09 2016-10-18 Washington University Ligand directed toroidal nanoparticles for therapy and diagnostic imaging
WO2009076414A2 (en) 2007-12-10 2009-06-18 Advanced Liquid Logic, Inc. Droplet actuator configurations and methods
WO2009111723A1 (en) 2008-03-07 2009-09-11 Drexel University Electrowetting microarray printing system and methods for bioactive tissue construct manufacturing
US8270148B2 (en) 2008-03-14 2012-09-18 David Griffith Suspension for a pressure sensitive touch display or panel
EP2303246A1 (en) * 2008-06-05 2011-04-06 President and Fellows of Harvard College Polymersomes, colloidosomes, liposomes, and other species associated with fluidic droplets
US9156010B2 (en) 2008-09-23 2015-10-13 Bio-Rad Laboratories, Inc. Droplet-based assay system
GB0909154D0 (en) 2008-09-25 2009-07-08 Nanomaterials Tech Pte Ltd A process for making particles for delivery of drug nanoparticles
US20110250688A1 (en) 2008-11-24 2011-10-13 Immunotrex Corporation Three Dimensional Tissue Generation
WO2010110471A1 (ja) * 2009-03-23 2010-09-30 国立大学法人北海道大学 脂質膜構造体
JP5487666B2 (ja) 2009-03-23 2014-05-07 コニカミノルタ株式会社 内水相を固定化することを特徴とするリポソームの製造方法
EP2253378A1 (de) 2009-05-13 2010-11-24 Ibidi Gmbh Verfahren zum Positionieren einer organischen, biologischen und/oder medizinischen Probe
GB0913823D0 (en) 2009-08-07 2009-09-16 Isis Innovation Bilayers
US8992984B1 (en) * 2009-10-21 2015-03-31 Stc.Unm Protocells and their use for targeted delivery of multicomponent cargos to cancer cells
US9039998B2 (en) 2010-03-04 2015-05-26 Institut National De La Sante Et De La Recherche Medical (Inserm) Bioprinting station, assembly comprising such bioprinting station and bioprinting method
US20110312537A1 (en) 2010-06-17 2011-12-22 Geneasys Pty Ltd Loc device for amplifying and detecting target nucleic acid sequences using electrochemiluminescent resonant energy transfer, linear probes with covalently attached primers
US20120006681A1 (en) 2010-07-06 2012-01-12 Kaler Karan V I S Controlled Dispensing of Ultrafine, Variable Volume, Emulsion Droplets
CN103167868B (zh) 2010-10-14 2016-08-03 株式会社爱茉莉太平洋 包覆有脂质的水凝胶粒子及其制备方法
KR101550941B1 (ko) 2010-10-14 2015-09-07 (주)아모레퍼시픽 리피드가 코팅된 하이드로겔 입자 및 이의 제조방법
AU2011318437B2 (en) 2010-10-21 2015-02-26 Organovo, Inc. Devices, systems, and methods for the fabrication of tissue
JP2012166159A (ja) 2011-02-15 2012-09-06 Microjet:Kk 吐出装置および吐出する方法
US8944083B2 (en) 2011-06-15 2015-02-03 Ut-Battelle, Llc Generation of monodisperse droplets by shape-induced shear and interfacial controlled fusion of individual droplets on-demand
WO2013041983A1 (en) 2011-09-19 2013-03-28 Centre National De La Recherche Scientifique Microfluidic system
GB201119032D0 (en) 2011-11-03 2011-12-14 Isis Innovation Multisomes: encapsulated droplet networks
US20130319861A1 (en) 2012-05-30 2013-12-05 Berkeley Lights, Inc. Outputting A Droplet Of Liquid Medium From A Device For Processing Micro-Objects In The Medium
US9223317B2 (en) 2012-06-14 2015-12-29 Advanced Liquid Logic, Inc. Droplet actuators that include molecular barrier coatings
US20140023697A1 (en) 2012-07-17 2014-01-23 Iona College Methods and systems for nanomembrane crystallization
GB201219196D0 (en) 2012-10-25 2012-12-12 Isis Innovation Droplet assembly method
GB201219201D0 (en) 2012-10-25 2012-12-12 Isis Innovation Hydrogel network
JP6375301B2 (ja) 2012-10-26 2018-08-15 オックスフォード ナノポール テクノロジーズ リミテッド 液滴界面
KR102449271B1 (ko) 2012-12-07 2022-09-29 옥스포드 유니버시티 이노베이션 리미티드 3d 프린팅에 의한 비말 어셈블리

Also Published As

Publication number Publication date
KR20140097303A (ko) 2014-08-06
KR102038450B1 (ko) 2019-11-26
US20140356289A1 (en) 2014-12-04
US10548852B2 (en) 2020-02-04
GB201119032D0 (en) 2011-12-14
CN104053497B (zh) 2017-04-26
BR112014010811A8 (pt) 2018-01-02
CN104053497A (zh) 2014-09-17
CA2853966C (en) 2021-07-06
US20200214988A1 (en) 2020-07-09
US11998642B2 (en) 2024-06-04
JP2015501328A (ja) 2015-01-15
CA2853966A1 (en) 2013-05-10
EP2773451A1 (en) 2014-09-10
AU2012330894B2 (en) 2017-07-13
US11406603B2 (en) 2022-08-09
JP6234371B2 (ja) 2017-11-22
AU2012330894A1 (en) 2014-05-29
US20230048266A1 (en) 2023-02-16
BR112014010811A2 (pt) 2017-05-02
WO2013064837A1 (en) 2013-05-10
BR112014010811B1 (pt) 2022-07-12

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