IN2014CN04155A - - Google Patents

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Publication number
IN2014CN04155A
IN2014CN04155A IN4155CHN2014A IN2014CN04155A IN 2014CN04155 A IN2014CN04155 A IN 2014CN04155A IN 4155CHN2014 A IN4155CHN2014 A IN 4155CHN2014A IN 2014CN04155 A IN2014CN04155 A IN 2014CN04155A
Authority
IN
India
Prior art keywords
aice
aices
actinoplanes
sequence
resembles
Prior art date
Application number
Inventor
Andreas Klein
Klaus Selber
Hermann Wehlmann
Winfried Rosen
Alfred Pühler
Patrick Schwientek
Jörn Kalinowski
Udo Wehmeier
Original Assignee
Bayer Ip Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ip Gmbh filed Critical Bayer Ip Gmbh
Publication of IN2014CN04155A publication Critical patent/IN2014CN04155A/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/365—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Actinoplanes (G)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/76—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Actinomyces; for Streptomyces
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C12P19/28—N-glycosides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The present invention is directed to an innate DNA sequence within the complete genome sequence of Actinoplanes sp. SE50/110 which resembles the structure of an actinomycete integrative and conjugative element (AICE). Related AICEs were used for establishing genetic manipulation tools for other bacteria in the past. In this document we describe the unique features of the specific AICE found in Actinoplanes sp. SE50/110 which are clearly distinct from any other known AICE as a whole but share minor parts with varying sequence similarity with other characterized AiCEs from other species.
IN4155CHN2014 2011-12-08 2012-12-04 IN2014CN04155A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP11192618 2011-12-08
PCT/EP2012/074366 WO2013083566A1 (en) 2011-12-08 2012-12-04 New actinomycete integrative and conjugative element from actinoplanes sp. se50/110 as plasmid for genetic transformation of related actinobacteria

Publications (1)

Publication Number Publication Date
IN2014CN04155A true IN2014CN04155A (en) 2015-07-17

Family

ID=47278320

Family Applications (1)

Application Number Title Priority Date Filing Date
IN4155CHN2014 IN2014CN04155A (en) 2011-12-08 2012-12-04

Country Status (12)

Country Link
US (2) US9217154B2 (en)
EP (1) EP2788373B1 (en)
JP (1) JP2015501641A (en)
KR (1) KR20140109922A (en)
CN (1) CN104144942A (en)
AR (1) AR089117A1 (en)
CA (1) CA2858259A1 (en)
ES (1) ES2718331T3 (en)
HK (1) HK1203970A1 (en)
IL (1) IL232587A (en)
IN (1) IN2014CN04155A (en)
WO (1) WO2013083566A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2015501641A (en) 2011-12-08 2015-01-19 バイエル・インテレクチュアル・プロパティ・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツングＢａｙｅｒ Ｉｎｔｅｌｌｅｃｔｕａｌ Ｐｒｏｐｅｒｔｙ ＧｍｂＨ A novel actinomycete-integrating junction element from Actinoplanes sp. SE50 / 110 as a plasmid for genetic transformation of related actinobacteria
CN112522174B (en) * 2020-12-25 2022-08-09 上海交通大学 Method for improving acarbose fermentation level by knocking out negative regulatory protein gene
CN112592878B (en) * 2020-12-25 2022-08-26 上海交通大学 Method for enhancing expression of positive regulatory protein gene to improve acarbose fermentation level

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2064092C2 (en) 1970-12-28 1983-06-01 Bayer Ag, 5090 Leverkusen Actinomycete glycoside hydrolase inhibitors
DE2209834C3 (en) 1972-03-01 1978-04-20 Bayer Ag, 5090 Leverkusen Manufacture of saccharase inhibitors
DE2347782C3 (en) 1973-09-22 1979-10-11 Bayer Ag, 5090 Leverkusen Amino sugar derivatives, processes for their preparation and medicaments containing these compounds
US4062950A (en) 1973-09-22 1977-12-13 Bayer Aktiengesellschaft Amino sugar derivatives
EP0796915A3 (en) * 1996-03-22 1999-04-14 Bayer Ag Process for the preparation and use of acarviosyl-transferase in the conversion of ascarbose-homologous in acarbose and in the preparation of acarbose-homologous
KR20100034055A (en) * 2007-07-27 2010-03-31 와이어쓰 엘엘씨 Vectors and methods for cloning gene clusters or portions thereof
TW201217533A (en) * 2010-08-04 2012-05-01 Bayer Pharma AG Genomics of actinoplanes utahensis
JP2015501641A (en) 2011-12-08 2015-01-19 バイエル・インテレクチュアル・プロパティ・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツングＢａｙｅｒ Ｉｎｔｅｌｌｅｃｔｕａｌ Ｐｒｏｐｅｒｔｙ ＧｍｂＨ A novel actinomycete-integrating junction element from Actinoplanes sp. SE50 / 110 as a plasmid for genetic transformation of related actinobacteria

Also Published As

Publication number Publication date
EP2788373B1 (en) 2019-01-23
JP2015501641A (en) 2015-01-19
HK1203970A1 (en) 2015-11-06
US9217154B2 (en) 2015-12-22
WO2013083566A1 (en) 2013-06-13
ES2718331T3 (en) 2019-07-01
AR089117A1 (en) 2014-07-30
US9562249B2 (en) 2017-02-07
US20140349346A1 (en) 2014-11-27
CA2858259A1 (en) 2013-06-13
EP2788373A1 (en) 2014-10-15
KR20140109922A (en) 2014-09-16
CN104144942A (en) 2014-11-12
US20160130622A1 (en) 2016-05-12
IL232587A0 (en) 2014-06-30
IL232587A (en) 2017-08-31

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