IN2014DN02166A - - Google Patents
Info
- Publication number
- IN2014DN02166A IN2014DN02166A IN2166DEN2014A IN2014DN02166A IN 2014DN02166 A IN2014DN02166 A IN 2014DN02166A IN 2166DEN2014 A IN2166DEN2014 A IN 2166DEN2014A IN 2014DN02166 A IN2014DN02166 A IN 2014DN02166A
- Authority
- IN
- India
- Prior art keywords
- palmitoyl
- acetylglycerol
- preparing
- optically active
- racemate
- Prior art date
Links
- JJEYQTYWEVZYLY-UHFFFAOYSA-N (3-acetyloxy-2-hydroxypropyl) hexadecanoate Chemical compound CCCCCCCCCCCCCCCC(=O)OCC(O)COC(C)=O JJEYQTYWEVZYLY-UHFFFAOYSA-N 0.000 abstract 4
- 238000000034 method Methods 0.000 abstract 3
- 239000013543 active substance Substances 0.000 abstract 2
- 239000011541 reaction mixture Substances 0.000 abstract 2
- 239000000126 substance Substances 0.000 abstract 2
- GAKUNXBDVGLOFS-DUZKARGPSA-N (1-acetyloxy-3-hexadecanoyloxypropan-2-yl) (9z,12z)-octadeca-9,12-dienoate Chemical compound CCCCCCCCCCCCCCCC(=O)OCC(COC(C)=O)OC(=O)CCCCCCC\C=C/C\C=C/CCCCC GAKUNXBDVGLOFS-DUZKARGPSA-N 0.000 abstract 1
- QHZLMUACJMDIAE-UHFFFAOYSA-N 1-monopalmitoylglycerol Chemical compound CCCCCCCCCCCCCCCC(=O)OCC(O)CO QHZLMUACJMDIAE-UHFFFAOYSA-N 0.000 abstract 1
- GAKUNXBDVGLOFS-UHFFFAOYSA-N PLA Natural products CCCCCCCCCCCCCCCC(=O)OCC(COC(C)=O)OC(=O)CCCCCCCC=CCC=CCCCCC GAKUNXBDVGLOFS-UHFFFAOYSA-N 0.000 abstract 1
- 239000012345 acetylating agent Substances 0.000 abstract 1
- 238000004440 column chromatography Methods 0.000 abstract 1
- 238000000746 purification Methods 0.000 abstract 1
- 229930195734 saturated hydrocarbon Natural products 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C67/00—Preparation of carboxylic acid esters
- C07C67/08—Preparation of carboxylic acid esters by reacting carboxylic acids or symmetrical anhydrides with the hydroxy or O-metal group of organic compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C67/00—Preparation of carboxylic acid esters
- C07C67/30—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
- C07C67/307—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by introduction of halogen; by substitution of halogen atoms by other halogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B57/00—Separation of optically-active compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C67/00—Preparation of carboxylic acid esters
- C07C67/10—Preparation of carboxylic acid esters by reacting carboxylic acids or symmetrical anhydrides with ester groups or with a carbon-halogen bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C67/00—Preparation of carboxylic acid esters
- C07C67/14—Preparation of carboxylic acid esters from carboxylic acid halides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C67/00—Preparation of carboxylic acid esters
- C07C67/48—Separation; Purification; Stabilisation; Use of additives
- C07C67/52—Separation; Purification; Stabilisation; Use of additives by change in the physical state, e.g. crystallisation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/02—Esters of acyclic saturated monocarboxylic acids having the carboxyl group bound to an acyclic carbon atom or to hydrogen
- C07C69/22—Esters of acyclic saturated monocarboxylic acids having the carboxyl group bound to an acyclic carbon atom or to hydrogen having three or more carbon atoms in the acid moiety
- C07C69/30—Esters of acyclic saturated monocarboxylic acids having the carboxyl group bound to an acyclic carbon atom or to hydrogen having three or more carbon atoms in the acid moiety esterified with trihydroxylic compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/34—Esters of acyclic saturated polycarboxylic acids having an esterified carboxyl group bound to an acyclic carbon atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Crystallography & Structural Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR1020110096341A KR101278874B1 (ko) | 2011-09-23 | 2011-09-23 | 1-팔미토일-3-아세틸글리세롤의 제조방법 및 이를 이용한 1-팔미토일-2-리놀레오일-3-아세틸글리세롤의 제조방법 |
| PCT/KR2012/007644 WO2013043009A2 (ko) | 2011-09-23 | 2012-09-24 | 1-팔미토일-3-아세틸글리세롤의 제조방법 및 이를 이용한 1-팔미토일-2-리놀레오일-3-아세틸글리세롤의 제조방법 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IN2014DN02166A true IN2014DN02166A (de) | 2015-05-15 |
Family
ID=47915041
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN2166DEN2014 IN2014DN02166A (de) | 2011-09-23 | 2012-09-24 |
Country Status (11)
| Country | Link |
|---|---|
| US (3) | US20140243548A1 (de) |
| EP (1) | EP2759529B1 (de) |
| JP (1) | JP5799171B2 (de) |
| KR (1) | KR101278874B1 (de) |
| CN (1) | CN103827075B (de) |
| AU (1) | AU2012310342B2 (de) |
| CA (1) | CA2849289C (de) |
| ES (1) | ES2620103T3 (de) |
| IN (1) | IN2014DN02166A (de) |
| RU (1) | RU2566826C1 (de) |
| WO (1) | WO2013043009A2 (de) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101278874B1 (ko) | 2011-09-23 | 2013-06-26 | 주식회사 엔지켐생명과학 | 1-팔미토일-3-아세틸글리세롤의 제조방법 및 이를 이용한 1-팔미토일-2-리놀레오일-3-아세틸글리세롤의 제조방법 |
| RU2636615C2 (ru) | 2013-08-19 | 2017-11-24 | Энзикем Лайфсайенсиз Корпорейшн | Композиция для предотвращения или лечения астмы, содержащая моноацетилдиацилглицериновое соединение в качестве активного ингредиента |
| US9808438B2 (en) | 2015-11-09 | 2017-11-07 | Enzychem Lifesciences Corporation | Method for treating mucositis |
| US10555923B2 (en) | 2015-11-14 | 2020-02-11 | Enzychem Lifesciences Corporation | Method for treating paroxysmal nocturnal hemoglobinuria |
| US10653657B2 (en) | 2015-11-14 | 2020-05-19 | Enzychem Lifesciences Corporation | Method for treating hemolytic uremic syndrome |
| WO2019106632A1 (en) | 2017-11-30 | 2019-06-06 | Enzychem Lifesciences Corporation | Compositions for prevention or treatment of acute radiation syndrome |
| KR102333606B1 (ko) | 2019-10-15 | 2021-12-01 | 주식회사 엔지켐생명과학 | 1-팔미토일-2-리놀레오일-3-아세틸 글리세롤의 제조 방법 |
| RU2758793C1 (ru) * | 2021-03-29 | 2021-11-01 | Федеральное Государственное Бюджетное Образовательное Учреждение Высшего Образования «Новосибирский Государственный Технический Университет» | Адаптивная стартер-генераторная система |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0694438B2 (ja) * | 1985-11-06 | 1994-11-24 | 株式会社ツムラ | 新規なグリセリン誘導体 |
| JPH0694438A (ja) | 1992-09-14 | 1994-04-05 | Matsushita Electric Works Ltd | 光切断法による外観検査装置 |
| JP3408337B2 (ja) * | 1994-10-05 | 2003-05-19 | 花王株式会社 | グリセリン誘導体の製造法 |
| JPH09110787A (ja) * | 1995-10-11 | 1997-04-28 | Hoechst Japan Ltd | 無溶媒反応による１級アルコールとフェノールのアセチル化方法 |
| DK0847994T3 (da) * | 1996-12-11 | 2003-07-28 | Hoffmann La Roche | Fremgangsmåde til fremstilling af blandede anhydrider |
| WO1999026640A1 (en) * | 1997-11-20 | 1999-06-03 | Bukwang Pharm. Ind. Co., Ltd. | Pharmaceutical composition containing extracts of cervus nippon antlers having growth-stimulating activities of hematopoietic stem cells and megakaryocytes |
| KR100291743B1 (ko) | 1997-11-20 | 2001-05-15 | 전길자 | 글리세롤 유도체의 제조방법 |
| KR100283010B1 (ko) | 1997-11-20 | 2001-04-02 | 전길자 | 녹용 추출물을 함유하는 조혈모세포 및 혈소판 전구세포 증식촉진용 조성물 |
| KR20010008387A (ko) * | 2000-11-30 | 2001-02-05 | 이성권 | 결정화방법을 이용한 고순도 불포화지방산의 분리 정제 방법 |
| WO2005090274A1 (en) * | 2004-03-22 | 2005-09-29 | Enzychem Co., Ltd | Process for regioselective preparation of glycerol, derivative and intermediate therefor |
| KR20050118057A (ko) * | 2004-04-24 | 2005-12-15 | 김상희 | 아세틸디아실글리세롤류의 화합물을 유효성분으로함유하는 항암제 및 건강식품 |
| KR100789323B1 (ko) * | 2005-07-20 | 2007-12-28 | 주식회사 엔지켐 | 글리세롤 유도체의 위치 선택적 제조방법 및 그 중간체 |
| WO2010006261A1 (en) * | 2008-07-10 | 2010-01-14 | Hong John J | Methods for inducing stem cell migration and specialization with ec-18 |
| KR101278874B1 (ko) | 2011-09-23 | 2013-06-26 | 주식회사 엔지켐생명과학 | 1-팔미토일-3-아세틸글리세롤의 제조방법 및 이를 이용한 1-팔미토일-2-리놀레오일-3-아세틸글리세롤의 제조방법 |
| JP6094438B2 (ja) | 2013-09-27 | 2017-03-15 | トヨタ自動車株式会社 | 内燃機関の制御装置 |
-
2011
- 2011-09-23 KR KR1020110096341A patent/KR101278874B1/ko active Active
-
2012
- 2012-09-24 WO PCT/KR2012/007644 patent/WO2013043009A2/ko not_active Ceased
- 2012-09-24 EP EP12834214.4A patent/EP2759529B1/de active Active
- 2012-09-24 RU RU2014116232/04A patent/RU2566826C1/ru active
- 2012-09-24 ES ES12834214.4T patent/ES2620103T3/es active Active
- 2012-09-24 AU AU2012310342A patent/AU2012310342B2/en active Active
- 2012-09-24 CA CA2849289A patent/CA2849289C/en active Active
- 2012-09-24 JP JP2014531727A patent/JP5799171B2/ja active Active
- 2012-09-24 IN IN2166DEN2014 patent/IN2014DN02166A/en unknown
- 2012-09-24 US US14/346,783 patent/US20140243548A1/en not_active Abandoned
- 2012-09-24 CN CN201280046277.7A patent/CN103827075B/zh active Active
-
2015
- 2015-12-03 US US14/958,734 patent/US9701613B2/en active Active
-
2017
- 2017-03-03 US US15/448,728 patent/US20170183287A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| AU2012310342A1 (en) | 2014-04-03 |
| JP5799171B2 (ja) | 2015-10-21 |
| US9701613B2 (en) | 2017-07-11 |
| WO2013043009A3 (ko) | 2013-05-30 |
| EP2759529A2 (de) | 2014-07-30 |
| US20170183287A1 (en) | 2017-06-29 |
| KR20130032628A (ko) | 2013-04-02 |
| AU2012310342B2 (en) | 2015-11-26 |
| EP2759529A4 (de) | 2015-05-20 |
| KR101278874B1 (ko) | 2013-06-26 |
| CN103827075A (zh) | 2014-05-28 |
| JP2014528945A (ja) | 2014-10-30 |
| CN103827075B (zh) | 2015-09-16 |
| ES2620103T3 (es) | 2017-06-27 |
| RU2566826C1 (ru) | 2015-10-27 |
| US20140243548A1 (en) | 2014-08-28 |
| CA2849289C (en) | 2016-05-10 |
| WO2013043009A2 (ko) | 2013-03-28 |
| US20160083329A1 (en) | 2016-03-24 |
| EP2759529B1 (de) | 2016-12-21 |
| CA2849289A1 (en) | 2013-03-28 |
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