IN2014DN03121A - - Google Patents

Download PDF

Info

Publication number
IN2014DN03121A
IN2014DN03121A IN3121DEN2014A IN2014DN03121A IN 2014DN03121 A IN2014DN03121 A IN 2014DN03121A IN 3121DEN2014 A IN3121DEN2014 A IN 3121DEN2014A IN 2014DN03121 A IN2014DN03121 A IN 2014DN03121A
Authority
IN
India
Prior art keywords
alkyl
halogen
hydrogen
necessary
further substituted
Prior art date
Application number
Other languages
English (en)
Inventor
Marko Mihovilovic
Michael Schnürch
Karlheinz Hilber
Xaver König
Thomas Linder
Agnes Mike
Original Assignee
Univ Wien Tech
Univ Wien Med
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Wien Tech, Univ Wien Med filed Critical Univ Wien Tech
Publication of IN2014DN03121A publication Critical patent/IN2014DN03121A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0657—Cardiomyocytes; Heart cells
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D251/00—Heterocyclic compounds containing 1,3,5-triazine rings
    • C07D251/02—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings
    • C07D251/12—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D251/26—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hetero atoms directly attached to ring carbon atoms
    • C07D251/40—Nitrogen atoms
    • C07D251/42—One nitrogen atom
    • C07D251/44—One nitrogen atom with halogen atoms attached to the two other ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D251/00—Heterocyclic compounds containing 1,3,5-triazine rings
    • C07D251/02—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings
    • C07D251/12—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D251/26—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hetero atoms directly attached to ring carbon atoms
    • C07D251/40—Nitrogen atoms
    • C07D251/42—One nitrogen atom
    • C07D251/46—One nitrogen atom with oxygen or sulfur atoms attached to the two other ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D251/00—Heterocyclic compounds containing 1,3,5-triazine rings
    • C07D251/02—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings
    • C07D251/12—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D251/26—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hetero atoms directly attached to ring carbon atoms
    • C07D251/40—Nitrogen atoms
    • C07D251/48—Two nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D251/00—Heterocyclic compounds containing 1,3,5-triazine rings
    • C07D251/02—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings
    • C07D251/12—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D251/26—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hetero atoms directly attached to ring carbon atoms
    • C07D251/40—Nitrogen atoms
    • C07D251/48—Two nitrogen atoms
    • C07D251/50—Two nitrogen atoms with a halogen atom attached to the third ring carbon atom
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/999—Small molecules not provided for elsewhere
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
    • C12N2506/30—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from cancer cells, e.g. reversion of tumour cells

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Cardiology (AREA)
  • Microbiology (AREA)
  • Rheumatology (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
IN3121DEN2014 2011-09-21 2012-09-21 IN2014DN03121A (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ATA1364/2011A AT511441B1 (de) 2011-09-21 2011-09-21 Triazin-derivate als differenzierungsbeschleuniger
PCT/AT2012/050140 WO2013040622A1 (de) 2011-09-21 2012-09-21 Triazin-derivate als differenzierungsbeschleuniger

Publications (1)

Publication Number Publication Date
IN2014DN03121A true IN2014DN03121A (de) 2015-06-26

Family

ID=47142831

Family Applications (1)

Application Number Title Priority Date Filing Date
IN3121DEN2014 IN2014DN03121A (de) 2011-09-21 2012-09-21

Country Status (5)

Country Link
US (1) US9611457B2 (de)
EP (1) EP2758378A1 (de)
AT (1) AT511441B1 (de)
IN (1) IN2014DN03121A (de)
WO (1) WO2013040622A1 (de)

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MXPA03008888A (es) * 2001-03-29 2005-03-07 Vertex Pharma Inhibidores de n-terminal c-jun cinasas (jnk) y otras proteinas cinasas.
GB0512324D0 (en) 2005-06-16 2005-07-27 Novartis Ag Organic compounds
DE102007034679A1 (de) * 2007-07-25 2009-01-29 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Materialzusammensetzungen, welche aus exokrinem Drüsengewebe erhaltene adulte Stammzellen enthalten, insbesondere zur Verwendung in der Regenerationsmedizin, z.B. zur Wiederherstellung von verletztem oder geschädigtem Myokardgewebe
WO2010144423A1 (en) * 2009-06-09 2010-12-16 Abraxis Bioscience, Llc Styryl-triazine derivatives and their therapeutical applications
CA2782577A1 (en) * 2009-12-02 2011-06-09 Research Development Foundation Selection of stem cell clones with defined differentiation capabilities
AT509266B1 (de) 2009-12-28 2014-07-15 Univ Wien Tech Substituierte pyridine und pyrimidine
WO2011088031A1 (en) * 2010-01-13 2011-07-21 Glaxosmithkline Llc Compounds and methods

Also Published As

Publication number Publication date
AT511441A4 (de) 2012-12-15
AT511441B1 (de) 2012-12-15
US9611457B2 (en) 2017-04-04
WO2013040622A1 (de) 2013-03-28
EP2758378A1 (de) 2014-07-30
US20140234965A1 (en) 2014-08-21

Similar Documents

Publication Publication Date Title
MX358376B (es) Nuevos derivados dihidroquinolina-2-ona.
EA201390884A1 (ru) Азабензимидазолы в качестве противовирусных средств в отношении респираторного синцитиального вируса
PH12014500584A1 (en) New bicyclic dihydroquinoline-2-one derivatives
MD4807B1 (ro) Derivaţi de pirimidiniloxi-benzen utilizaţi ca erbicide
PH12014501179B1 (en) New bicyclic dihydroisoquinoline-1-one derivatives
PH12014501365A1 (en) Compounds
MX352928B (es) Compuestos de piridazina-amida.
MX2015001099A (es) Nuevos derivados biciclicos de piridina.
PH12014502697B1 (en) New diazaspirocycloalkane and azaspirocycloalkane
PH12014501979A1 (en) Fused bicyclic 2,4-diaminopyrimidine derivative as a dual alk and fak inhibitor
MY169267A (en) New aryl-quinoline derivatives
MX2021014531A (es) Compuestos de aminopurina sustituida, composiciones del mismo, y metodos de tratamiento con los mismos.
TN2015000261A1 (fr) Dérivés d'imidazopyridazine servant de modulateurs des recepteurs gabaa
PH12015501363A1 (en) Chloro-pyrazine carboxamide derivatives with epithelial sodium channel blocking activity
MX2014014531A (es) Derivados de aminoquinazolina y piridopirimidina.
MX2015007097A (es) Nuevas fenil-piridinas/pirazinas bi-anulares para el tratamiento de cancer.
MX2014002208A (es) Inhibidores de serina/treonina quinasa.
MX343225B (es) Nuevos derivados de aril-benzocicloalquil-amida.
MX380421B (es) Compuestos herbicidas de pirimidiniloxi benceno sustituido.
PH12015502232A1 (en) Naphthyridine derivatives useful as alpha-v-beta-6 integrin antagonists
MX353190B (es) Derivados de isoquinolina y naftiridina.
MY160902A (en) Process for the preparation of the L-arginine salt of perindopril
MX346980B (es) Nuevos compuestos de hexahidrociclopentapirrolona, hexahidropirrolopirrolona, octahidropirrolopiridinona y octahidropiridinona.
MX2015016332A (es) Inhibidores de alk biciclicos fusionados.
MX369470B (es) Medios y método para el tratamiento de tumores sólidos.