IN2014KN01319A - - Google Patents
Info
- Publication number
- IN2014KN01319A IN2014KN01319A IN1319KON2014A IN2014KN01319A IN 2014KN01319 A IN2014KN01319 A IN 2014KN01319A IN 1319KON2014 A IN1319KON2014 A IN 1319KON2014A IN 2014KN01319 A IN2014KN01319 A IN 2014KN01319A
- Authority
- IN
- India
- Prior art keywords
- formula
- cinacalcet
- pharmaceutically acceptable
- acceptable salts
- ethylamine
- Prior art date
Links
- VDHAWDNDOKGFTD-MRXNPFEDSA-N cinacalcet Chemical compound N([C@H](C)C=1C2=CC=CC=C2C=CC=1)CCCC1=CC=CC(C(F)(F)F)=C1 VDHAWDNDOKGFTD-MRXNPFEDSA-N 0.000 abstract 3
- 229960003315 cinacalcet Drugs 0.000 abstract 3
- 238000000034 method Methods 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- RUJHATQMIMUYKD-UHFFFAOYSA-N 2-naphthalen-1-ylethanamine Chemical compound C1=CC=C2C(CCN)=CC=CC2=C1 RUJHATQMIMUYKD-UHFFFAOYSA-N 0.000 abstract 1
- QWXKQVIMGVVIBX-UHFFFAOYSA-N 3-[3-(trifluoromethyl)phenyl]propan-1-ol Chemical compound OCCCC1=CC=CC(C(F)(F)F)=C1 QWXKQVIMGVVIBX-UHFFFAOYSA-N 0.000 abstract 1
- 230000029936 alkylation Effects 0.000 abstract 1
- 238000005804 alkylation reaction Methods 0.000 abstract 1
- 239000003054 catalyst Substances 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
- C07C209/04—Preparation of compounds containing amino groups bound to a carbon skeleton by substitution of functional groups by amino groups
- C07C209/14—Preparation of compounds containing amino groups bound to a carbon skeleton by substitution of functional groups by amino groups by substitution of hydroxy groups or of etherified or esterified hydroxy groups
- C07C209/16—Preparation of compounds containing amino groups bound to a carbon skeleton by substitution of functional groups by amino groups by substitution of hydroxy groups or of etherified or esterified hydroxy groups with formation of amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CZ20110770A CZ2011770A3 (cs) | 2011-11-25 | 2011-11-25 | Zpusob výroby Cinacalcetu |
| PCT/CZ2012/000119 WO2013075679A1 (en) | 2011-11-25 | 2012-11-21 | A method of producing cinacalcet |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IN2014KN01319A true IN2014KN01319A (cs) | 2015-10-16 |
Family
ID=47435672
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN1319KON2014 IN2014KN01319A (cs) | 2011-11-25 | 2012-11-21 |
Country Status (7)
| Country | Link |
|---|---|
| CN (1) | CN103958456B (cs) |
| BR (1) | BR112014012434A2 (cs) |
| CZ (1) | CZ2011770A3 (cs) |
| HU (1) | HUP1400341A3 (cs) |
| IL (1) | IL232678A (cs) |
| IN (1) | IN2014KN01319A (cs) |
| WO (1) | WO2013075679A1 (cs) |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6011068A (en) | 1991-08-23 | 2000-01-04 | Nps Pharmaceuticals, Inc. | Calcium receptor-active molecules |
| US5504253A (en) | 1994-07-15 | 1996-04-02 | Nps Pharmaceuticals, Inc. | Amine preparation |
| ES2285707T3 (es) | 1994-10-21 | 2007-11-16 | Nps Pharmaceuticals, Inc. | Compuestos activos frente al receptor de calcio. |
| EP1881954B1 (en) * | 2005-05-16 | 2009-09-16 | Teva Pharmaceutical Industries Ltd. | Process for preparing cinacalcet hydrochloride |
| JP4638491B2 (ja) * | 2005-05-23 | 2011-02-23 | テバ ファーマシューティカル インダストリーズ リミティド | シナカルセト塩酸塩結晶フォームｉの調製方法 |
| US7449603B2 (en) | 2006-04-27 | 2008-11-11 | Teva Pharmaceutical Industries Ltd. | Process for the preparation of cinacalcet base |
| KR20080011320A (ko) | 2006-04-27 | 2008-02-01 | 테바 파마슈티컬 인더스트리즈 리미티드 | 시나칼셋 염기의 제조 방법 |
| AR061310A1 (es) | 2006-06-08 | 2008-08-20 | Medichem Sa | Procesos para preparar compuestos intermediarios utiles para la preparacion de cinacalcet |
| EP2170805B1 (en) * | 2007-06-21 | 2016-03-16 | Amgen Inc. | Methods of synthesizing cinacalcet and salts thereof |
| SI2358659T1 (sl) * | 2008-10-28 | 2013-04-30 | Zach System S.P.A. | Postopek za pripravo cinakalceta |
-
2011
- 2011-11-25 CZ CZ20110770A patent/CZ2011770A3/cs not_active IP Right Cessation
-
2012
- 2012-11-21 CN CN201280057515.4A patent/CN103958456B/zh active Active
- 2012-11-21 IN IN1319KON2014 patent/IN2014KN01319A/en unknown
- 2012-11-21 BR BR112014012434A patent/BR112014012434A2/pt not_active IP Right Cessation
- 2012-11-21 HU HU1400341A patent/HUP1400341A3/hu unknown
- 2012-11-21 WO PCT/CZ2012/000119 patent/WO2013075679A1/en not_active Ceased
-
2014
- 2014-05-18 IL IL232678A patent/IL232678A/en active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| IL232678A (en) | 2017-05-29 |
| HUP1400341A3 (en) | 2014-12-29 |
| BR112014012434A2 (pt) | 2017-06-06 |
| IL232678A0 (en) | 2014-08-03 |
| CZ303627B6 (cs) | 2013-01-16 |
| CN103958456A (zh) | 2014-07-30 |
| CZ2011770A3 (cs) | 2013-01-16 |
| HUP1400341A2 (en) | 2014-10-28 |
| CN103958456B (zh) | 2015-10-21 |
| WO2013075679A1 (en) | 2013-05-30 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| BR112014007674A2 (pt) | método para produzir derivados de 4,4-diflúor-3,4-dihidroisoquinolina | |
| BR112014006237A2 (pt) | método para produzir para-xileno, uso do para-xileno, método para produzir ácido tereftálico, método para produzir um composto | |
| TN2013000347A1 (en) | Production method of optically active dihydrobenzofuran derivative | |
| AR076027A1 (es) | Metodos e intermediarios para la preparacion de agentes farmaceuticos | |
| BR112014001418A2 (pt) | compostos, processo para a preparação dos compostos, e, uso dos compostos | |
| SG10201804021TA (en) | Methods of preparing inhibitors of influenza viruses replication | |
| MX359825B (es) | Compuesto pirazol y su uso farmaceutico. | |
| BR112013032690A2 (pt) | método para produzir um composto, composto, e, uso do mesmo | |
| ES2603227T3 (es) | Proceso para la preparación de compuestos cetólidos | |
| JO2930B1 (en) | A new process for the synthesis of ivabradine and salts of addition with a pharmaceutically acceptable acid | |
| IN2014KN01319A (cs) | ||
| JO3189B1 (ar) | طريقة جديدة لتخليق (e2) -3- (3, 4- داي ميثوكسي فينيل)بروب-2 - يننيتريل واستخدامها لتخليق ايفابرادين والاملاح المضافة منها مع حمض مقبول صيدلانيا | |
| UA111329C2 (uk) | Спосіб синтезу івабрадину і його адитивних солей з фармацевтично прийнятною кислотою | |
| ES2556470T3 (es) | Procedimiento para preparar [3-[(6-cloro-3-piridinil)metil]-2-tiazolidiniliden]cianamida | |
| UA117900C2 (uk) | Спосіб синтезу 3-(2-бром-4,5-диметоксифеніл)пропаннітрилу та застосування в синтезі івабрадину та його адитивних солей з фармацевтично прийнятною кислотою | |
| IN2014DE01203A (cs) | ||
| BR112013008664A2 (pt) | polimorfos de hidrocloreto de 4-metilbenzoato de 4-[2-dimetilamino-1-(1-hidroxiciclohexil)etil]fenila, métodos para a preparação dos mesmos e utilização dos mesmos | |
| BR112014011748A2 (pt) | composto, processo para preparar um composto, e, uso de um composto | |
| BR112013015903A2 (pt) | polimorfo cristalino, processo para preparar um polimorfo, composição farmacêutica, forma purificada do polimorfo, uso de um polimorfo, processo para preparar um composto, e, composto. | |
| MX2013002656A (es) | Nuevo proceso. | |
| UA111156C2 (uk) | Спосіб синтезу івабрадину і його адитивних солей з фармацевтично прийнятною кислотою | |
| MX2013011705A (es) | Nuevo procedimiento de sintesis del 3-(2-bromo-4,5-dimetoxifenil)p ropanonitrilo, y aplicacion a la sintesis de la ivabradina y de sus sales de adicion a un acido farmaceuticamente aceptable. | |
| BR112013020015A2 (pt) | (5s,8s)-3-(4'-cloro-3'-flúor-4-metilbifenil-3-il)-4-hidróxi-8-metóxi-1-azaspiro[4.5]dec-3-en-2-ona (composto a) para terapia | |
| BR112014002522A2 (pt) | processo para a preparação de um composto, uso do composto e composto | |
| GEP20156369B (en) | New process for synthesis of ivabradine and addition salts therewith pharmaceutically acceptable acid |