IN2014MN01101A - - Google Patents
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- Publication number
- IN2014MN01101A IN2014MN01101A IN1101MUN2014A IN2014MN01101A IN 2014MN01101 A IN2014MN01101 A IN 2014MN01101A IN 1101MUN2014 A IN1101MUN2014 A IN 1101MUN2014A IN 2014MN01101 A IN2014MN01101 A IN 2014MN01101A
- Authority
- IN
- India
- Prior art keywords
- methods
- pharmacomap
- predicting
- test drug
- drugs
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5014—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing toxicity
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
- G01N33/5041—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects involving analysis of members of signalling pathways
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/82—Translation products from oncogenes
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Hematology (AREA)
- Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Molecular Biology (AREA)
- Toxicology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
Described herein are methods of screening drugs in a non human animal using high resolution technology leading to generation of pharmacomaps. Further described herein are methods of predicting the therapeutic benefit and/or toxicity of drug candidate compounds. In specific embodiments provided herein are methods of predicting the clinical effects of a test drug based on comparison of the pharmacomap of the test drug to the pharmacomap of one or more reference drugs with known clinical outcomes.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161558877P | 2011-11-11 | 2011-11-11 | |
| PCT/US2012/064440 WO2013071099A1 (en) | 2011-11-11 | 2012-11-09 | A drug screening method and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IN2014MN01101A true IN2014MN01101A (en) | 2015-07-03 |
Family
ID=48290605
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN1101MUN2014 IN2014MN01101A (en) | 2011-11-11 | 2012-11-09 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20140297199A1 (en) |
| EP (1) | EP2777074A4 (en) |
| JP (1) | JP2015507470A (en) |
| CN (1) | CN104040719A (en) |
| CA (1) | CA2854469A1 (en) |
| IN (1) | IN2014MN01101A (en) |
| MX (1) | MX2014005710A (en) |
| WO (1) | WO2013071099A1 (en) |
Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2007536644A (en) | 2004-05-06 | 2007-12-13 | ザ・レジェンツ・オブ・ザ・ユニバーシティ・オブ・カリフォルニア | Method and system for aligning and classifying images |
| ES2684591T3 (en) * | 2013-07-29 | 2018-10-03 | The Regents Of The University Of California | Real-time feedback system control technology platform with dynamically changing stimulations |
| WO2016145366A1 (en) | 2015-03-11 | 2016-09-15 | Timothy Ragan | System and methods for serial staining and imaging |
| CN104850864A (en) * | 2015-06-01 | 2015-08-19 | 深圳英智源智能系统有限公司 | Unsupervised image recognition method based on convolutional neural network |
| US11462303B2 (en) | 2016-09-12 | 2022-10-04 | Cornell University | Computational systems and methods for improving the accuracy of drug toxicity predictions |
| WO2018094290A1 (en) | 2016-11-18 | 2018-05-24 | Tissuevision, Inc. | Automated tissue section capture, indexing and storage system and methods |
| US10303961B1 (en) * | 2017-04-13 | 2019-05-28 | Zoox, Inc. | Object detection and passenger notification |
| CN106990077A (en) * | 2017-06-15 | 2017-07-28 | 福建师范大学 | It is a kind of based on the micro- high throughput screening system with microfluidic chip technology of multi-photon |
| EP3451190B1 (en) | 2017-09-04 | 2020-02-26 | Sap Se | Model-based analysis in a relational database |
| CN108766587B (en) * | 2018-05-11 | 2022-05-03 | 北京诺道认知医学科技有限公司 | Method and device for constructing drug administration database based on specified drugs |
| JP6559850B1 (en) * | 2018-07-27 | 2019-08-14 | Ｋａｒｙｄｏ ＴｈｅｒａｐｅｕｔｉＸ株式会社 | Artificial intelligence model for predicting the effects of test substances in humans |
| US11486950B2 (en) * | 2018-08-01 | 2022-11-01 | General Electric Company | Systems and methods for automated graphical prescription with deep neural networks |
| JP6558786B1 (en) * | 2018-09-28 | 2019-08-14 | 学校法人東北工業大学 | Method, computer system, and program for predicting target characteristics |
| EP3644228B1 (en) * | 2018-10-23 | 2024-08-14 | The Chinese University Of Hong Kong | Method and apparatus for segmenting cellular image |
| KR102307479B1 (en) * | 2019-02-12 | 2021-09-30 | 단국대학교 천안캠퍼스 산학협력단 | For producing and using method of brain map based on neurotransmitters |
| US20220113288A1 (en) * | 2019-02-12 | 2022-04-14 | Neurovis Inc. | Neurotransmitter-based brain mapping method and use of brain map |
| CN109709129A (en) * | 2019-02-13 | 2019-05-03 | 李秀利 | A kind of MR imaging method of high flux screening drug |
| US11808760B1 (en) * | 2019-02-14 | 2023-11-07 | Curi Bio, Inc. | System and methods for in vitro structural toxicity testing |
| CN113678143A (en) * | 2019-02-20 | 2021-11-19 | 蓝岩治疗有限公司 | Detection of target cells in large image datasets using artificial intelligence |
| CN110178757B (en) * | 2019-04-19 | 2021-08-27 | 广东医科大学附属医院 | Zebra fish brain trauma model and preparation method and application thereof |
| JP7536860B2 (en) * | 2019-08-13 | 2024-08-20 | サノフイ | Predicting Patient Responses to Chemicals |
| CA3158327A1 (en) * | 2019-10-17 | 2021-04-22 | Karydo Therapeutix, Inc. | Artificial intelligence model for predicting indications for test substances in humans |
| CN110850070B (en) * | 2019-11-22 | 2021-06-01 | 北京大学 | Method for evaluating reproductive development toxicity of chemical substances based on fluorescence labeling transgenic animal model |
| CN111061729B (en) * | 2019-11-29 | 2021-04-16 | 武汉大学 | Granularity-considered vector tile organization method |
| US12241830B2 (en) * | 2019-12-06 | 2025-03-04 | Broad Institute, Inc. | Living biosensors |
| CN111062346A (en) * | 2019-12-21 | 2020-04-24 | 电子科技大学 | Automatic leukocyte positioning detection and classification recognition system and method |
| US11605038B1 (en) | 2020-05-18 | 2023-03-14 | Vignet Incorporated | Selecting digital health technology to achieve data collection compliance in clinical trials |
| US11461216B1 (en) | 2020-05-18 | 2022-10-04 | Vignet Incorporated | Monitoring and improving data collection using digital health technology |
| CN111657861B (en) * | 2020-06-04 | 2022-02-25 | 浙江大学 | Thrombolytic drug effect evaluation method based on two-photon microscope technology |
| US20230374590A1 (en) * | 2021-09-14 | 2023-11-23 | Massachusetts Institute Of Technology | Methods and reagent for diagnosing bipolar disorder |
| WO2024168475A1 (en) * | 2023-02-13 | 2024-08-22 | 深圳先进技术研究院 | Evaluation method and device for comparing anti-anxiety effects of different medicines with efficiency |
| CN116369275B (en) * | 2023-03-01 | 2025-03-28 | 山东师范大学 | A method for constructing an animal model for specifically manipulating somatostatin neurons |
| EP4731105A1 (en) | 2023-06-26 | 2026-04-29 | Conceivable Life Sciences, Inc. | Intelligent automated in vitro fertilization and intracytoplasmic sperm injection platform background |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7998704B2 (en) * | 2002-03-07 | 2011-08-16 | Carnegie Mellon University | Methods for magnetic resonance imaging |
| US8952213B2 (en) * | 2002-04-26 | 2015-02-10 | The Board Of Trustees Of The Leland Stanford Junior University | Neuronal activation in a transgenic model |
| US7372985B2 (en) * | 2003-08-15 | 2008-05-13 | Massachusetts Institute Of Technology | Systems and methods for volumetric tissue scanning microscopy |
| CN101484806A (en) * | 2006-05-17 | 2009-07-15 | 协乐民公司 | Method for automated tissue analysis |
-
2012
- 2012-11-09 US US14/356,975 patent/US20140297199A1/en not_active Abandoned
- 2012-11-09 JP JP2014541325A patent/JP2015507470A/en active Pending
- 2012-11-09 CA CA2854469A patent/CA2854469A1/en not_active Abandoned
- 2012-11-09 CN CN201280066634.6A patent/CN104040719A/en active Pending
- 2012-11-09 MX MX2014005710A patent/MX2014005710A/en unknown
- 2012-11-09 IN IN1101MUN2014 patent/IN2014MN01101A/en unknown
- 2012-11-09 EP EP12847222.2A patent/EP2777074A4/en not_active Withdrawn
- 2012-11-09 WO PCT/US2012/064440 patent/WO2013071099A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| CN104040719A (en) | 2014-09-10 |
| EP2777074A4 (en) | 2015-08-19 |
| JP2015507470A (en) | 2015-03-12 |
| EP2777074A1 (en) | 2014-09-17 |
| US20140297199A1 (en) | 2014-10-02 |
| MX2014005710A (en) | 2015-03-09 |
| CA2854469A1 (en) | 2013-05-16 |
| WO2013071099A1 (en) | 2013-05-16 |