IN2014MN02126A - - Google Patents
Info
- Publication number
- IN2014MN02126A IN2014MN02126A IN2126MUN2014A IN2014MN02126A IN 2014MN02126 A IN2014MN02126 A IN 2014MN02126A IN 2126MUN2014 A IN2126MUN2014 A IN 2126MUN2014A IN 2014MN02126 A IN2014MN02126 A IN 2014MN02126A
- Authority
- IN
- India
- Prior art keywords
- compounds
- calcium
- crac
- channel
- formula
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 abstract 3
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 abstract 2
- 150000001669 calcium Chemical class 0.000 abstract 2
- 229910052791 calcium Inorganic materials 0.000 abstract 2
- 239000011575 calcium Substances 0.000 abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- 201000010099 disease Diseases 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 208000011580 syndromic disease Diseases 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Rheumatology (AREA)
- Pulmonology (AREA)
- Cardiology (AREA)
- Pain & Pain Management (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN2126MUN2014 IN2014MN02126A (fr) | 2012-05-02 | 2013-05-01 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN6KO2012 | 2012-05-02 | ||
| IN2126MUN2014 IN2014MN02126A (fr) | 2012-05-02 | 2013-05-01 | |
| PCT/IB2013/053440 WO2013164769A1 (fr) | 2012-05-02 | 2013-05-01 | Composés substitués de pyridine en tant que modulateurs de crac |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IN2014MN02126A true IN2014MN02126A (fr) | 2015-09-11 |
Family
ID=48428565
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN2126MUN2014 IN2014MN02126A (fr) | 2012-05-02 | 2013-05-01 |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US9399638B2 (fr) |
| EP (1) | EP2844655A1 (fr) |
| AU (1) | AU2013255437A1 (fr) |
| CA (1) | CA2871270A1 (fr) |
| IN (1) | IN2014MN02126A (fr) |
| WO (1) | WO2013164769A1 (fr) |
| ZA (1) | ZA201407685B (fr) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10703722B2 (en) | 2010-04-27 | 2020-07-07 | Calcimedica, Inc. | Compounds that modulate intracellular calcium |
| US9242969B2 (en) | 2013-03-14 | 2016-01-26 | Novartis Ag | Biaryl amide compounds as kinase inhibitors |
| WO2014203217A1 (fr) | 2013-06-21 | 2014-12-24 | Lupin Limited | Composés hétérocycliques substitués utiles en tant que modulateurs de crac |
| WO2014207648A1 (fr) | 2013-06-24 | 2014-12-31 | Lupin Limited | Dérivés de chromane et de chromène et leur utilisation en tant que modulateurs de crac |
| WO2015090579A1 (fr) * | 2013-12-18 | 2015-06-25 | Grünenthal GmbH | Carboxamides à base de pyrazolyle servant d'inhibiteurs de canal crac |
| CN105367547B (zh) * | 2014-08-19 | 2019-04-23 | 北京桦冠生物技术有限公司 | 一种噁唑啉酮抗生素的新合成工艺 |
| UY36294A (es) | 2014-09-12 | 2016-04-29 | Novartis Ag | Compuestos y composiciones como inhibidores de quinasa |
| CA2968299A1 (fr) | 2014-11-18 | 2016-05-26 | Rutgers, The State University Of New Jersey | Nouveaux decouplants mitochondriaux pour le traitement de maladies metaboliques et du cancer |
| EP3778595B1 (fr) * | 2015-02-27 | 2021-08-25 | Calcimedica, Inc. | Traitement de la pancréatite |
| US20180161388A1 (en) | 2015-05-18 | 2018-06-14 | Beth Israel Deaconess Medical Center, Inc. | Substance p, mast cell degranulation inhibitors, and peripheral neuropathy |
| PL3303330T3 (pl) * | 2015-06-03 | 2019-10-31 | Bristol Myers Squibb Co | Agoniści 4 - hydroksy - 3 - ( heteroarylo ) pirydyno - 2 - onowi receptora apj do stosowania w leczeniu zaburzeń sercowo-naczyniowych |
| CA2995094A1 (fr) | 2015-08-07 | 2017-02-16 | Calcimedica, Inc. | Utilisation d'inhibiteurs du canal crac pour le traitement d'un accident vasculaire cerebral et d'une lesion cerebrale traumatique |
| US10227315B2 (en) | 2016-05-18 | 2019-03-12 | Rutgers, The State University Of New Jersey | Mitochondrial uncouplers for treatment of metabolic diseases and cancer |
| AU2017329090B9 (en) | 2016-09-19 | 2019-09-05 | Novartis Ag | Therapeutic combinations comprising a RAF inhibitor and a ERK inhibitor |
| CA3057969A1 (fr) | 2017-05-02 | 2018-11-08 | Novartis Ag | Polytherapie |
| US11919902B2 (en) * | 2017-12-22 | 2024-03-05 | Hibercell, Inc. | Aryl-bipyridine amine derivatives as phosphatidylinositol phosphate kinase inhibitors |
| BR112020018094A2 (pt) | 2018-03-08 | 2020-12-22 | Incyte Corporation | Compostos de aminopirazina diol como inibidores de pi3k-¿ |
| US11046658B2 (en) | 2018-07-02 | 2021-06-29 | Incyte Corporation | Aminopyrazine derivatives as PI3K-γ inhibitors |
| WO2020053834A1 (fr) | 2018-09-14 | 2020-03-19 | Rhizen Pharmaceuticals Sa | Compositions comprenant un inhibiteur de crac et un corticostéroïde ainsi que leurs méthodes d'utilisation |
| EP3969449B1 (fr) | 2019-05-13 | 2025-02-12 | Novartis AG | Nouvelles formes cristallines de n-(3-(2-(2-hydroxyéthoxy)-6-morpholinopyridin-4-yl)-4-méthylphényl)-2(trifluorométhyl)isonicotinamide servant d'inhibiteurs de raf pour le traitement du cancer |
| CN110407740A (zh) * | 2019-09-04 | 2019-11-05 | 上海毕得医药科技有限公司 | 一种3-溴-2-乙基吡啶的合成方法 |
| JP2023528537A (ja) | 2020-03-20 | 2023-07-04 | カルシメディカ，インク． | 急性肺傷害及び急性呼吸窮迫症候群を処置するための方法及び組成物 |
| CA3198798A1 (fr) | 2020-11-13 | 2022-05-19 | Kenneth Stauderman | Synthese amelioree d'inhibiteurs de canal crac |
| EP4516778A4 (fr) | 2022-04-25 | 2026-04-29 | Nippon Shinyaku Co Ltd | Composé servant d'inhibiteur de ddr1 kinase et médicament |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI376370B (en) | 2003-07-23 | 2012-11-11 | Synta Pharmaceuticals Corp | Compounds for inflammation and immune-related uses |
| KR20070057965A (ko) | 2004-09-21 | 2007-06-07 | 신타 파마슈티칼스 코프. | 염증 및 면역 관련 용도를 위한 화합물 |
| KR20140018997A (ko) | 2005-01-07 | 2014-02-13 | 신타 파마슈티칼스 코프. | 염증 및 면역 관련 용도를 위한 화합물 |
| EP1846388A4 (fr) | 2005-01-25 | 2011-12-07 | Synta Pharmaceuticals Corp | Composes de thiophene utilises contre l'inflammation et les troubles lies a l'immunite |
| PL1848435T3 (pl) | 2005-01-25 | 2016-08-31 | Synta Pharmaceuticals Corp | Związki przeciwko zapaleniom i zastosowania związane z odpornością |
| TW200806641A (en) | 2006-01-25 | 2008-02-01 | Synta Pharmaceuticals Corp | Substituted aromatic compounds for inflammation and immune-related uses |
| TW200806290A (en) | 2006-01-25 | 2008-02-01 | Synta Pharmaceuticals Corp | Substituted biaryl compounds for inflammation and immune-related uses |
| WO2007087429A2 (fr) | 2006-01-25 | 2007-08-02 | Synta Pharmaceuticals Corp. | Composés à base de phényle et de pyridyle pour des utilisations liées aux inflammations ou aux troubles immunitaires |
| US20070254926A1 (en) | 2006-01-31 | 2007-11-01 | Jun Jiang | Pyridylphenyl compounds for inflammation and immune-related uses |
| ES2528797T3 (es) | 2006-08-21 | 2015-02-12 | Genentech, Inc. | Compuestos de aza-benzotiofenilo y métodos de uso |
| CA2695148A1 (fr) | 2007-08-01 | 2009-02-05 | Synta Pharmaceuticals Corp. | Composes pyridine utilises pour des etats inflammatoires et des troubles immunitaires |
| PT2195311E (pt) | 2007-08-17 | 2011-05-25 | Actelion Pharmaceuticals Ltd | Derivados de piridina como moduladores do receptor s1p1/edg1 |
| US8263641B2 (en) | 2007-09-10 | 2012-09-11 | Calcimedica, Inc. | Compounds that modulate intracellular calcium |
| US8389567B2 (en) | 2007-12-12 | 2013-03-05 | Calcimedica, Inc. | Compounds that modulate intracellular calcium |
| CA2725726A1 (fr) | 2008-05-23 | 2009-11-26 | Glaxo Group Limited | Composes contenant de l'azote tricyclique et utilisation de ceux-ci comme antibacteriens |
| DE102008031299B4 (de) | 2008-07-02 | 2014-10-30 | Acandis Gmbh & Co. Kg | Filter für ein Blutgefäß |
| TWI392673B (zh) | 2008-08-27 | 2013-04-11 | Calcimedica Inc | 調控細胞內鈣離子濃度之化合物 |
| US8524763B2 (en) | 2008-09-22 | 2013-09-03 | Calcimedica, Inc. | Inhibitors of store operated calcium release |
| AU2009300318A1 (en) | 2008-10-01 | 2010-04-08 | Synta Pharmaceuticals Corp. | Compounds for inflammation and immune-related uses |
| TW201111380A (en) | 2009-08-26 | 2011-04-01 | Astrazeneca Ab | Heterocyclic urea derivatives and methods of use thereof |
| EP2477982A4 (fr) | 2009-09-16 | 2013-04-03 | Calcimedica Inc | Composés qui modulent le calcium intracellulaire |
| AU2011322068B2 (en) | 2010-10-30 | 2015-11-05 | Lupin Limited | Oxazoline and isoxazoline derivatives as CRAC modulators |
| CA2834928C (fr) | 2011-05-03 | 2017-10-17 | Synta Pharmaceuticals Corp. | Composes pour une inflammation et des utilisations apparentees au systeme immunitaire |
| WO2013059677A1 (fr) | 2011-10-19 | 2013-04-25 | Calcimedica, Inc. | Composés qui modulent le calcium intracellulaire |
| WO2013059666A1 (fr) | 2011-10-19 | 2013-04-25 | Calcimedica, Inc. | Composés qui modulent le calcium intracellulaire |
-
2013
- 2013-05-01 CA CA2871270A patent/CA2871270A1/fr not_active Abandoned
- 2013-05-01 US US14/398,154 patent/US9399638B2/en not_active Expired - Fee Related
- 2013-05-01 AU AU2013255437A patent/AU2013255437A1/en not_active Abandoned
- 2013-05-01 WO PCT/IB2013/053440 patent/WO2013164769A1/fr not_active Ceased
- 2013-05-01 EP EP13722111.5A patent/EP2844655A1/fr not_active Withdrawn
- 2013-05-01 IN IN2126MUN2014 patent/IN2014MN02126A/en unknown
-
2014
- 2014-10-22 ZA ZA2014/07685A patent/ZA201407685B/en unknown
-
2016
- 2016-06-20 US US15/186,882 patent/US20160304506A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| WO2013164769A1 (fr) | 2013-11-07 |
| AU2013255437A1 (en) | 2014-11-13 |
| US20150111900A1 (en) | 2015-04-23 |
| EP2844655A1 (fr) | 2015-03-11 |
| US9399638B2 (en) | 2016-07-26 |
| CA2871270A1 (fr) | 2013-11-07 |
| ZA201407685B (en) | 2015-11-25 |
| US20160304506A1 (en) | 2016-10-20 |
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