IN2014MN02338A - - Google Patents

Info

Publication number
IN2014MN02338A
IN2014MN02338A IN2338MUN2014A IN2014MN02338A IN 2014MN02338 A IN2014MN02338 A IN 2014MN02338A IN 2338MUN2014 A IN2338MUN2014 A IN 2338MUN2014A IN 2014MN02338 A IN2014MN02338 A IN 2014MN02338A
Authority
IN
India
Prior art keywords
inhibitors
relates
present
tec
members
Prior art date
Application number
Other languages
English (en)
Inventor
Alain Laurent
Yannick Rose
James B Jaquith
Original Assignee
Pharmascience Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CA2779184A external-priority patent/CA2779184A1/en
Priority claimed from CA2813299A external-priority patent/CA2813299A1/en
Application filed by Pharmascience Inc filed Critical Pharmascience Inc
Publication of IN2014MN02338A publication Critical patent/IN2014MN02338A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/05—Isotopically modified compounds, e.g. labelled

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Transplantation (AREA)
  • Oncology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
IN2338MUN2014 2012-05-31 2013-05-28 IN2014MN02338A (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CA2779184A CA2779184A1 (en) 2012-05-31 2012-05-31 Protein kinase inhibitors
CA2813299A CA2813299A1 (en) 2013-04-17 2013-04-17 Protein kinase inhibitors
PCT/CA2013/000513 WO2013177668A1 (en) 2012-05-31 2013-05-28 Protein kinase inhibitors

Publications (1)

Publication Number Publication Date
IN2014MN02338A true IN2014MN02338A (de) 2015-08-14

Family

ID=49672221

Family Applications (1)

Application Number Title Priority Date Filing Date
IN2338MUN2014 IN2014MN02338A (de) 2012-05-31 2013-05-28

Country Status (11)

Country Link
US (1) US9796716B2 (de)
EP (1) EP2855484A4 (de)
JP (1) JP6175495B2 (de)
KR (2) KR20190043648A (de)
CN (1) CN104379586B (de)
BR (1) BR112014029718A2 (de)
CA (1) CA2874211A1 (de)
HK (1) HK1208460A1 (de)
IN (1) IN2014MN02338A (de)
RU (1) RU2678767C2 (de)
WO (1) WO2013177668A1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2833867A1 (en) * 2013-11-21 2015-05-21 Pharmascience Inc. Protein kinase inhibitors
CA2834528A1 (en) * 2013-11-26 2015-05-26 Pharmascience Inc. Protein kinase inhibitors
CN106573001B (zh) * 2014-07-07 2019-01-29 江苏恒瑞医药股份有限公司 作为蛋白激酶抑制剂的氨基哒嗪酮化合物
GB201508747D0 (en) 2015-05-21 2015-07-01 Univ Edinburgh Compounds
CA3025813A1 (en) * 2015-05-27 2016-12-01 Gb005, Inc. Inhibitors of the tec kinase enzyme family
KR102624961B1 (ko) 2015-12-07 2024-01-16 디아이씨 가부시끼가이샤 중합성 화합물의 제조 방법
WO2017134685A2 (en) * 2016-02-02 2017-08-10 Sun Pharma Advanced Research Company Limited Novel hydrazino compounds as btk inhibitors
CN109369654A (zh) * 2018-11-20 2019-02-22 山东大学 1，3-二取代-4-氨基吡唑并嘧啶类化合物及其制备方法和应用
CN111454268B (zh) * 2019-01-18 2023-09-08 明慧医药（上海）有限公司 作为布鲁顿酪氨酸激酶抑制剂的环状分子
US20250042904A1 (en) * 2021-11-15 2025-02-06 Wigen Biomedicine Technology (shanghai) Co., Ltd. Compounds used as src inhibitors

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003509428A (ja) * 1999-09-17 2003-03-11 アボツト・ゲー・エム・ベー・ハー・ウント・コンパニー・カーゲー 治療薬としてのピラゾロピリミジン
MXPA02002938A (es) 1999-09-17 2004-12-06 Abbott Gmbh & Co Kg Inhibidores de cinasa como agentes agentes terapeuticos.
US6921763B2 (en) * 1999-09-17 2005-07-26 Abbott Laboratories Pyrazolopyrimidines as therapeutic agents
NZ514403A (en) * 1999-12-27 2002-10-25 Japan Tobacco Inc Fused-ring compounds and use thereof as drugs
AUPR392301A0 (en) 2001-03-23 2001-04-26 University Of Newcastle Research Associates Limited, The Protein phosphatase inhibitors
US20040248906A1 (en) * 2001-08-10 2004-12-09 Donato Nicholas J Use of c-src inhibitors alone or in combination with st1571 for the treatment of leukaemia
DK2526933T3 (en) 2006-09-22 2015-05-18 Pharmacyclics Inc Inhibitors of Bruton's tyrosine kinase
SG10202107066WA (en) * 2007-03-28 2021-07-29 Pharmacyclics Llc Inhibitors of bruton's tyrosine kinase
US7718662B1 (en) * 2009-10-12 2010-05-18 Pharmacyclics, Inc. Pyrazolo-pyrimidine inhibitors of bruton's tyrosine kinase
WO2011046954A1 (en) * 2009-10-13 2011-04-21 Ligand Pharmaceuticals Inc. Hematopoietic growth factor mimetic small molecule compounds and their uses
WO2014187319A1 (en) * 2013-05-21 2014-11-27 Jiangsu Medolution Ltd Substituted pyrazolopyrimidines as kinases inhibitors
CN103787839B (zh) 2014-01-21 2015-12-02 苏州昊帆生物科技有限公司 合成2,3,4,5,6-五氟苯酚的方法

Also Published As

Publication number Publication date
US9796716B2 (en) 2017-10-24
RU2678767C2 (ru) 2019-02-01
KR20190043648A (ko) 2019-04-26
CN104379586A (zh) 2015-02-25
BR112014029718A2 (pt) 2017-06-27
KR20150015527A (ko) 2015-02-10
WO2013177668A1 (en) 2013-12-05
JP6175495B2 (ja) 2017-08-02
KR101972990B1 (ko) 2019-04-26
CN104379586B (zh) 2018-01-16
EP2855484A1 (de) 2015-04-08
EP2855484A4 (de) 2015-12-16
HK1208460A1 (en) 2016-03-04
JP2015518009A (ja) 2015-06-25
US20150191473A1 (en) 2015-07-09
CA2874211A1 (en) 2013-12-05
RU2014145285A (ru) 2016-07-20

Similar Documents

Publication Publication Date Title
IN2014MN02338A (de)
ZA201405140B (en) Disubstituted benzothienyl-pyrolotriazines and their use as fgfr kinase inhibitors
ZA201600648B (en) Novel pyrrolopyrimidine compounds as inhibitors of protein kinases
PT2833973T (pt) Compostos úteis como inibidores da cinase atr e terapias de combinação dos mesmos
ZA201502783B (en) Azaquinazoline inhibitors of atypical protein kinase c
PH12013501922A1 (en) Protein kinase inhibitors
IN2015DN00127A (de)
SI2880035T1 (sl) Nove spojine pirolopirimidina kot inhibitorji protein kinaz
MX2022000026A (es) Anticuerpos para tau.
EP2833889A4 (de) Proteinkinase-c-hemmer und verwendungen davon
IL231484A (en) Protein kinase inhibitors
EP2870158A4 (de) Proteinkinasehemmer
ZA201602311B (en) (aza)pyridopyrazolopyrimidinones and indazolopyrimidinones as inhibitors of fibrinolysis
IL237158A0 (en) Amino quinzolines as kinase inhibitors
EP2895166A4 (de) Aminoisochinolinderivate als proteinkinasehemmer
MX393754B (es) Metodos y composiciones para inhibir cnksr1
MX354501B (es) Ingrediente perfumante de la familia galbano.
EP3042905A4 (de) Proteinkinasehemmer mit einem pyrrolopyridazinderivat
GB201209458D0 (en) Novel compounds and their use as kinase inhibitors
GB201206048D0 (en) Novel compounds and their use as kinase inhibitors
MY168958A (en) Intermediates and processes for preparing compounds
GB201309603D0 (en) Novel compounds and their use as kinase inhibitors