IN2015DN00017A - - Google Patents

Info

Publication number
IN2015DN00017A
IN2015DN00017A IN17DEN2015A IN2015DN00017A IN 2015DN00017 A IN2015DN00017 A IN 2015DN00017A IN 17DEN2015 A IN17DEN2015 A IN 17DEN2015A IN 2015DN00017 A IN2015DN00017 A IN 2015DN00017A
Authority
IN
India
Prior art keywords
constructs
cells
living
disclosed
potent
Prior art date
Application number
Other languages
English (en)
Inventor
Benjamin R Shepherd
Sharon C Presnell
Albert J Evinger
Original Assignee
Organovo Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Organovo Inc filed Critical Organovo Inc
Publication of IN2015DN00017A publication Critical patent/IN2015DN00017A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
    • A61L27/3834—Cells able to produce different cell types, e.g. hematopoietic stem cells, mesenchymal stem cells, marrow stromal cells, embryonic stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/08—Muscles; Tendons; Ligaments
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/28—Bones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3886—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells comprising two or more cell types
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/56—Porous materials, e.g. foams or sponges
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0062—General methods for three-dimensional culture
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0654—Osteocytes, Osteoblasts, Odontocytes; Bones, Teeth
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2502/00—Coculture with; Conditioned medium produced by
    • C12N2502/13—Coculture with; Conditioned medium produced by connective tissue cells; generic mesenchyme cells, e.g. so-called "embryonic fibroblasts"
    • C12N2502/1352—Mesenchymal stem cells
    • C12N2502/1358—Bone marrow mesenchymal stem cells (BM-MSC)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2502/00—Coculture with; Conditioned medium produced by
    • C12N2502/28—Vascular endothelial cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Cell Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Botany (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Immunology (AREA)
  • Vascular Medicine (AREA)
  • Molecular Biology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Food Science & Technology (AREA)
  • Toxicology (AREA)
  • Physics & Mathematics (AREA)
  • Tropical Medicine & Parasitology (AREA)
IN17DEN2015 2012-06-19 2013-06-19 IN2015DN00017A (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261661768P 2012-06-19 2012-06-19
US13/801,780 US20140099709A1 (en) 2012-06-19 2013-03-13 Engineered three-dimensional connective tissue constructs and methods of making the same
PCT/US2013/046519 WO2013192290A1 (fr) 2012-06-19 2013-06-19 Constructions manufacturées de tissu conjonctif tridimensionnel et leurs procédés de fabrication

Publications (1)

Publication Number Publication Date
IN2015DN00017A true IN2015DN00017A (fr) 2015-05-22

Family

ID=49769324

Family Applications (1)

Application Number Title Priority Date Filing Date
IN17DEN2015 IN2015DN00017A (fr) 2012-06-19 2013-06-19

Country Status (13)

Country Link
US (2) US20140099709A1 (fr)
EP (1) EP2861270A4 (fr)
JP (1) JP2015523142A (fr)
KR (1) KR20150020702A (fr)
CN (1) CN104717987A (fr)
AU (2) AU2013277275B2 (fr)
BR (1) BR112014032074A2 (fr)
HK (1) HK1210439A1 (fr)
IL (1) IL236183A0 (fr)
IN (1) IN2015DN00017A (fr)
RU (1) RU2015100977A (fr)
SG (1) SG11201408405WA (fr)
WO (1) WO2013192290A1 (fr)

Families Citing this family (64)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8241905B2 (en) 2004-02-24 2012-08-14 The Curators Of The University Of Missouri Self-assembling cell aggregates and methods of making engineered tissue using the same
JP5624981B2 (ja) 2008-06-24 2014-11-12 ザ・キュレーターズ・オブ・ザ・ユニバーシティ・オブ・ミズーリＴｈｅ Ｃｕｒａｔｏｒｓ Ｏｆｔｈｅ Ｕｎｉｖｅｒｓｉｔｙ Ｏｆ Ｍｉｓｓｏｕｒｉ 自己集合性多細胞体、および前記多細胞体を用いて３次元の生物構造体を作製する方法
US9719068B2 (en) 2010-05-06 2017-08-01 Children's Hospital Medical Center Methods and systems for converting precursor cells into intestinal tissues through directed differentiation
AU2011318437B2 (en) 2010-10-21 2015-02-26 Organovo, Inc. Devices, systems, and methods for the fabrication of tissue
WO2012068170A2 (fr) 2010-11-15 2012-05-24 Jau-Nan Lee Génération de cellules souches neurales à partir de cellules souches trophoblastiques humaines
HK1200483A1 (en) 2011-09-12 2015-08-07 奥加诺沃公司 Engineered tissues for in vitro research uses, arrays thereof, and methods of making the same
US9499779B2 (en) 2012-04-20 2016-11-22 Organovo, Inc. Devices, systems, and methods for the fabrication of tissue utilizing UV cross-linking
EP2919794B1 (fr) 2012-11-15 2021-01-20 AlloSource Systèmes de cartilage haché et méthodes associées
WO2014085493A1 (fr) 2012-11-30 2014-06-05 Jau-Nan Lee Méthodes de différenciation de cellules souches par modulation du mir-124
CA2894750C (fr) 2013-02-22 2021-12-14 Allosource Compositions de mosaique de cartilage et procedes afferents
AU2014236705B2 (en) 2013-03-15 2018-04-12 Allosource Perforated osteochondral allograft compositions
US9442105B2 (en) 2013-03-15 2016-09-13 Organovo, Inc. Engineered liver tissues, arrays thereof, and methods of making the same
SG11201600770RA (en) 2013-07-31 2016-02-26 Organovo Inc Automated devices, systems, and methods for the fabrication of tissue
EP3808838B1 (fr) * 2014-04-04 2024-04-10 Organovo, Inc. Tissu mammaire tridimensionnel artificiel, tissu adipeux, et modèle de maladies tumorales
SG10201801654RA (en) 2014-05-28 2018-04-27 Childrens Hospital Med Ct Methods and systems for converting precursor cells into gastric tissues through directed differentiation
KR101690872B1 (ko) 2014-08-19 2016-12-29 이화여자대학교 산학협력단 편도 유래 중간엽 줄기세포로부터 인슐린 분비 세포의 분화 방법
KR20170064547A (ko) 2014-10-06 2017-06-09 오가노보, 인크. 조작된 신장 조직, 이의 어레이, 및 이를 제조하는 방법
AU2015331848B2 (en) 2014-10-17 2022-03-03 Children's Hospital Medical Center, D/B/A Cincinnati Children's Hospital Medical Center In vivo model of human small intestine using pluripotent stem cells and methods of making and using same
US11529436B2 (en) 2014-11-05 2022-12-20 Organovo, Inc. Engineered three-dimensional skin tissues, arrays thereof, and methods of making the same
US10538725B1 (en) 2014-11-14 2020-01-21 Autodesk, Inc. Multi-dimensional bioprinting system
US9808490B2 (en) 2014-11-26 2017-11-07 Accelerated Biosciences Corp. Induced hepatocytes and uses thereof
KR20160115204A (ko) * 2015-03-26 2016-10-06 포항공과대학교 산학협력단 3차원 프린팅용 조성물, 이의 제조방법, 및 이를 사용한 3차원 구조체의 제조방법
KR102311639B1 (ko) * 2015-03-26 2021-10-12 주식회사 티앤알바이오팹 심근조직 재생용 3차원 구조체의 제조방법
WO2017008035A1 (fr) * 2015-07-08 2017-01-12 The Trustees Of The University Of Pennesylvania Échafaudages obtenus par ingénierie tissulaire dérivés d'organes décellularisés
EP3320925B1 (fr) 2015-07-10 2024-02-28 FUJIFILM Corporation Structure cellulaire et procédé permettant de produire une structure cellulaire
KR102078602B1 (ko) * 2015-07-23 2020-02-19 한국화학연구원 지방세포와 마크로파지의 3차원 공동 배양 방법
EP3359641B1 (fr) 2015-10-09 2020-01-08 DEKA Products Limited Partnership Système de bioréacteur et de pompage de fluide
WO2017083402A1 (fr) 2015-11-09 2017-05-18 Organovo, Inc. Procédés améliorés de fabrication de tissus
WO2017123722A1 (fr) 2016-01-12 2017-07-20 Cleveland State University Constructions biologiques miniatures imprimées en 3d
CN109415685B (zh) 2016-05-05 2023-07-04 儿童医院医疗中心 用于体外制造胃底组织的方法和与其相关的组合物
US11254901B2 (en) 2016-07-12 2022-02-22 Deka Products Limited Partnership System and method for printing tissue
US10345208B2 (en) 2016-07-12 2019-07-09 Deka Products Limited Partnership System and method for applying force to a device
EP3526007A4 (fr) 2016-10-12 2020-05-27 Advanced Biomatrix, Inc. Encres d'impression tridimensionnelles (3-d) fabriquées à partir de molécules de matrice extracellulaire naturelle
EP4553082A3 (fr) 2016-11-04 2025-08-20 Children's Hospital Medical Center Compositions d'organoïdes hépatiques et leurs procédés de fabrication et d'utilisation
US11299705B2 (en) 2016-11-07 2022-04-12 Deka Products Limited Partnership System and method for creating tissue
EP3541518A4 (fr) 2016-11-17 2020-09-30 Cleveland State University Plates-formes de puce pour la bio-impression 3d de microréseau
EP3548507A4 (fr) 2016-12-05 2020-07-15 Children's Hospital Medical Center Organoïdes du côlon et leurs procédés de préparation et d'utilisation
JP7248586B2 (ja) 2017-04-14 2023-03-29 チルドレンズ ホスピタル メディカル センター 複数ドナー幹細胞組成物およびそれを作製する方法
US12297416B2 (en) 2017-07-12 2025-05-13 Deka Products Limited Partneship System and method for transferring tissue
US10570362B2 (en) 2017-07-12 2020-02-25 Deka Products Limited Partnership System and method for transferring tissue
EP3694603B1 (fr) 2017-10-10 2026-04-08 Children's Hospital Medical Center Compositions de tissus oesophagiens et/ou d'organoïdes et leurs procédés de fabrication
US11262349B2 (en) 2017-10-11 2022-03-01 Cleveland State University Multiplexed immune cell assays on a micropillar/microwell chip platform
EP3697340A4 (fr) * 2017-10-20 2021-08-04 Indiana University Research & Technology Corporation Bio-impression 3d de cellules porcines sans échafaudage
EP3727394A4 (fr) 2017-12-21 2021-09-08 Children's Hospital Medical Center Organoïdes humains numérisés et méthodes d'utilisation de ceux-ci
PE20211587A1 (es) * 2018-01-31 2021-08-18 Rokit Healthcare Inc Composicion de tinta biologica para lamina para la regeneracion de la dermis, metodo de fabricacion de lamina personalizada para regeneracion de la dermis usando la misma, y lamina personalizada para regeneracion de la dermis fabricada con el metodo de fabricacion
CN108409917B (zh) * 2018-03-07 2021-03-30 广州锐澄医疗技术有限公司 一种羊膜固定器的制备方法
CO2018004340A1 (es) * 2018-04-24 2018-07-19 Univ Del Valle Implante para la regeneración de tejidos
EP4678727A3 (fr) 2018-07-26 2026-03-11 Children's Hospital Medical Center Tissus hépato-biliaire-pancréatiques et leurs procédés de fabrication
CA3112026A1 (fr) 2018-09-12 2020-03-19 Children's Hospital Medical Center Compositions d'organoides pour la production de cellules souches hematopoietiques et leurs derives
WO2020150310A1 (fr) * 2019-01-16 2020-07-23 University Of Utah Research Foundation Utilisation de feuilles de cellules souches mésenchymateuses pour prévenir la formation de cicatrices utérines
US12600943B2 (en) 2019-02-01 2026-04-14 The University Of Hong Kong Innervated organoid compositions and methods of making same
AU2020252089B2 (en) * 2019-03-29 2026-04-02 Kolon Tissuegene, Inc. Treatment of intervertebral disc degeneration
AU2020283048A1 (en) 2019-05-31 2021-12-23 Children's Hospital Medical Center Shaped organoid compositions and methods of making same
US12497597B2 (en) 2019-05-31 2025-12-16 Children's Hospital Medical Center Methods of generating and expanding hematopoietic stem cells
US11718823B2 (en) * 2020-02-03 2023-08-08 Purdue Research Foundation Methods and materials for rapid preparation of 3D spheroids/organoids
WO2021247907A1 (fr) * 2020-06-03 2021-12-09 Northeastern University Implant biodégradable pour l'administration trans-nasale prolongée d'agents thérapeutiques au niveau du cerveau
CN113941029B (zh) * 2020-07-17 2022-11-18 四川大学华西医院 一种3d打印神经导管及其应用
CN112251352B (zh) * 2020-09-29 2022-06-07 中国肉类食品综合研究中心 一种3d生物组织专用培养装置和块状培育肉的制备方法
CA3206143A1 (fr) 2021-02-26 2022-09-01 Wei Hsu Isolement de cellules souches squelettiques et leurs utilisations
CN113403268B (zh) * 2021-08-20 2022-01-07 北京大学第三医院（北京大学第三临床医学院） 一种含干细胞外泌体的生物墨水及其制造方法
JP2025506727A (ja) 2022-02-18 2025-03-13 エーディーエー フォーサイス インスティテュート， インコーポレイテッド 骨格幹細胞のマーカー及びその使用
KR102670562B1 (ko) * 2022-10-13 2024-05-29 바오밥헬스케어 주식회사 3차원 바이오프린팅 기술을 이용한 생선근육 형태 모사 근육을 포함하는 배양생선의 제조방법 및 이에 의해 제조된 배양생선
WO2024091824A1 (fr) 2022-10-26 2024-05-02 Ada Forsyth Institute, Inc. Différenciation et reprogrammation de chondrocyte
EP4375362A1 (fr) 2022-11-28 2024-05-29 Universität Zürich Insert de culture de tissu rotatif pour la position à l'intérieur d'une bouteille à rouleau rotatif partiellement remplie d'un liquide pour la culture de cellules

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060270032A1 (en) * 2005-05-24 2006-11-30 The Regents Of The University Of California Microscale micropatterened engineered in vitro tissue
US6998264B2 (en) * 2002-11-19 2006-02-14 Huntington Medical Research Institutes Replication of biological tissue
US20040197375A1 (en) * 2003-04-02 2004-10-07 Alireza Rezania Composite scaffolds seeded with mammalian cells
US8043614B2 (en) * 2004-03-09 2011-10-25 Ahlfors Jan-Eric W Autogenic living scaffolds and living tissue matrices: methods and uses thereof
US20090142307A1 (en) * 2004-07-09 2009-06-04 Athanasiou Kyriacos A Shape-Based Approach for Scaffoldless Tissue Engineering
JP5624981B2 (ja) * 2008-06-24 2014-11-12 ザ・キュレーターズ・オブ・ザ・ユニバーシティ・オブ・ミズーリＴｈｅ Ｃｕｒａｔｏｒｓ Ｏｆｔｈｅ Ｕｎｉｖｅｒｓｉｔｙ Ｏｆ Ｍｉｓｓｏｕｒｉ 自己集合性多細胞体、および前記多細胞体を用いて３次元の生物構造体を作製する方法
US20110250688A1 (en) * 2008-11-24 2011-10-13 Immunotrex Corporation Three Dimensional Tissue Generation
HUP0900819A2 (en) * 2009-05-05 2011-01-28 Pecsi Tudomanyegyetem Lung tissue culture
EP2450707B1 (fr) * 2010-11-04 2016-04-27 University of Pécs Modèle de tissu de poumon
WO2012003465A2 (fr) * 2010-07-01 2012-01-05 The Regents Of The University Of Michigan Constructions de fibroblaste de nerf en trois dimensions sans échafaudage
AU2011318437B2 (en) * 2010-10-21 2015-02-26 Organovo, Inc. Devices, systems, and methods for the fabrication of tissue
WO2013130823A1 (fr) * 2012-02-29 2013-09-06 Massachusetts Institute Of Technology Procédé de formation de motif inverse pour la micro-organisation en trois dimensions à compartiments multiples de plusieurs types de cellules
EP3808838B1 (fr) * 2014-04-04 2024-04-10 Organovo, Inc. Tissu mammaire tridimensionnel artificiel, tissu adipeux, et modèle de maladies tumorales

Also Published As

Publication number Publication date
SG11201408405WA (en) 2015-01-29
CA2876659A1 (fr) 2013-12-27
KR20150020702A (ko) 2015-02-26
CN104717987A (zh) 2015-06-17
EP2861270A4 (fr) 2016-01-20
AU2017200162A1 (en) 2017-02-02
HK1210439A1 (en) 2016-04-22
BR112014032074A2 (pt) 2017-06-27
US20190062707A1 (en) 2019-02-28
AU2013277275A1 (en) 2015-01-29
JP2015523142A (ja) 2015-08-13
AU2013277275B2 (en) 2016-10-13
US20140099709A1 (en) 2014-04-10
EP2861270A1 (fr) 2015-04-22
WO2013192290A1 (fr) 2013-12-27
RU2015100977A (ru) 2016-08-10
IL236183A0 (en) 2015-01-29

Similar Documents

Publication Publication Date Title
IN2015DN00017A (fr)
WO2013040078A3 (fr) Tissus artificiels pour des utilisations en recherche in vitro, puces de ces tissus et procédés de fabrication correspondants
WO2014153346A8 (fr) Ingénierie de cellules souches pluripotentes d'un tissu hétérogène
WO2012006440A3 (fr) Production de cellules endothéliales par programmation
MY169357A (en) Methods for additive manufacturing of implant components
EP4275618A3 (fr) Implant fenestré
WO2013106556A3 (fr) Prothèses mammaires, procédés de fabrication de prothèses mammaires, et procédés de traitement utilisant les prothèses mammaires
MX2011007930A (es) Conjugados de insulina cristalina.
WO2014186469A3 (fr) Application à des humains de lymphocytes t comprenant un récepteur antigénique chimérique (car)
BR112015005878A2 (pt) nanopartículas terapêuticas compreendendo agente terapêutico e métodos de preparar e usar as mesmas
EA201290988A1 (ru) Стереоселективный синтез фосфорсодержащих активных соединений
EP4403197A3 (fr) Formulations injectables pour l'augmentation d'organes
UA113541C2 (xx) Заміщені піролідин-2-карбоксаміди
MX359769B (es) Metodos para descelularizar huesos.
MX2013009175A (es) Composiciones que comprenden acido peroxi alfa-cetocarboxilico y metodos para producirlas y usarlas.
IN2014MN01981A (fr)
MX2013004061A (es) Analogos de ciclosporina.
MX390739B (es) Composicion de hueso comprimido y metodo para usar la misma.
WO2014141210A3 (fr) Cellules souches de pulpe dentaire immatures multifonctionnelles et applications thérapeutiques
SG10201901713RA (en) Extracellular matrix compositions
PL2552401T3 (pl) Zastosowanie preparatu otrzymanego z hodowli in vitro odróżnicowanych nieelicytowanych komórek drzewa arganowego, do leczenia starzenia się skóry
SG11201804755VA (en) Method for manufacturing tissue/organ by using blood cells
WO2012048170A3 (fr) Animaux humanisés par ingénierie tissulaire et leurs utilisations
IL231195A0 (en) A dental implant, a vascular implant and a tissue implant made of polytetrafluoroethylene with a three-dimensional porous structure
PH12020551126A1 (en) Modulation of heparin-binding epidermal growth factor activity for tympanic membrane healing