IN2015DN01751A - - Google Patents

Info

Publication number
IN2015DN01751A
IN2015DN01751A IN1751DEN2015A IN2015DN01751A IN 2015DN01751 A IN2015DN01751 A IN 2015DN01751A IN 1751DEN2015 A IN1751DEN2015 A IN 1751DEN2015A IN 2015DN01751 A IN2015DN01751 A IN 2015DN01751A
Authority
IN
India
Prior art keywords
alloy
less
elements
content ranging
remainder
Prior art date
Application number
Inventor
Thomas Imwinkelried
Stefan Beck
Peter Uggowitzer
Joerg Loeffler
Original Assignee
Synthes Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synthes Gmbh filed Critical Synthes Gmbh
Publication of IN2015DN01751A publication Critical patent/IN2015DN01751A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/02—Inorganic materials
    • A61L27/04—Metals or alloys
    • A61L27/047—Other specific metals or alloys not covered by A61L27/042 - A61L27/045 or A61L27/06
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws or setting implements
    • A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
    • A61B17/84—Fasteners therefor or fasteners being internal fixation devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/58—Materials at least partially resorbable by the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/02—Inorganic materials
    • A61L31/022—Metals or alloys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/148—Materials at least partially resorbable by the body
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B21—MECHANICAL METAL-WORKING WITHOUT ESSENTIALLY REMOVING MATERIAL; PUNCHING METAL
    • B21C—MANUFACTURE OF METAL SHEETS, WIRE, RODS, TUBES, PROFILES OR LIKE SEMI-MANUFACTURED PRODUCTS OTHERWISE THAN BY ROLLING; AUXILIARY OPERATIONS USED IN CONNECTION WITH METAL-WORKING WITHOUT ESSENTIALLY REMOVING MATERIAL
    • B21C23/00—Extruding metal; Impact extrusion
    • B21C23/002—Extruding materials of special alloys so far as the composition of the alloy requires or permits special extruding methods of sequences
    • C—CHEMISTRY; METALLURGY
    • C22—METALLURGY; FERROUS OR NON-FERROUS ALLOYS; TREATMENT OF ALLOYS OR NON-FERROUS METALS
    • C22C—ALLOYS
    • C22C23/00—Alloys based on magnesium
    • C—CHEMISTRY; METALLURGY
    • C22—METALLURGY; FERROUS OR NON-FERROUS ALLOYS; TREATMENT OF ALLOYS OR NON-FERROUS METALS
    • C22C—ALLOYS
    • C22C23/00—Alloys based on magnesium
    • C22C23/04—Alloys based on magnesium with zinc or cadmium as the next major constituent
    • C—CHEMISTRY; METALLURGY
    • C22—METALLURGY; FERROUS OR NON-FERROUS ALLOYS; TREATMENT OF ALLOYS OR NON-FERROUS METALS
    • C22F—CHANGING THE PHYSICAL STRUCTURE OF NON-FERROUS METALS AND NON-FERROUS ALLOYS
    • C22F1/00—Changing the physical structure of non-ferrous metals or alloys by heat treatment or by hot or cold working
    • C22F1/06—Changing the physical structure of non-ferrous metals or alloys by heat treatment or by hot or cold working of magnesium or alloys based thereon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00—Materials characterised by their function or physical properties
    • A61L2400/12—Nanosized materials, e.g. nanofibres, nanoparticles, nanowires, nanotubes; Nanostructured surfaces

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Mechanical Engineering (AREA)
  • Metallurgy (AREA)
  • Surgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Organic Chemistry (AREA)
  • Materials Engineering (AREA)
  • Vascular Medicine (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Inorganic Chemistry (AREA)
  • Dermatology (AREA)
  • Medicinal Chemistry (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Biomedical Technology (AREA)
  • Thermal Sciences (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Neurology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Cardiology (AREA)
  • Materials For Medical Uses (AREA)
  • Prostheses (AREA)
  • Powder Metallurgy (AREA)

Abstract

An alloy and an implant having a three dimensional structure based on such alloy. The alloy comprises a monophasic MgZn alloy containing from 2.0 wt. % Zn to 6 wt. % Zn having less than 0.001 wt. % of one or more other elements with the remainder being Mg. In some embodiments the alloy is substantially free of microgalvanic elements. In some embodiments the alloy includes a MgZnCa alloy containing nanosized precipitates being less noble than the Mg matrix alloy and having a Zn content ranging from 3.0 wt. % Zn to 6 wt. % Zn and a calcium content ranging from 0.0005 wt. % to 1.0 wt. % having less than 0.001 wt. % of one or more other elements with the remainder being Mg. In other embodiments the alloy includes a MgZnCa alloy containing nanosized precipitates being less noble than the Mg matrix alloy a plurality of nanosized precipitates being more noble than the Mg matrix and having a Zn content ranging from 3.0 wt. % Zn to 6 wt. % Zn a calcium content ranging from 0.0005 wt. % to 1.0 wt. % having less than 0.001 wt. % of one or more other elements with the remainder being Mg.
IN1751DEN2015 2012-08-31 2013-08-29 IN2015DN01751A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261695621P 2012-08-31 2012-08-31
US13/827,008 US9469889B2 (en) 2012-08-31 2013-03-14 Ultrapure magnesium alloy with adjustable degradation rate
PCT/US2013/057294 WO2014036262A1 (en) 2012-08-31 2013-08-29 Ultrapure magnesium alloy with adjustable degradation rate

Publications (1)

Publication Number Publication Date
IN2015DN01751A true IN2015DN01751A (en) 2015-05-29

Family

ID=49162261

Family Applications (1)

Application Number Title Priority Date Filing Date
IN1751DEN2015 IN2015DN01751A (en) 2012-08-31 2013-08-29

Country Status (10)

Country Link
US (2) US9469889B2 (en)
EP (1) EP2890824B1 (en)
JP (2) JP6752575B2 (en)
KR (1) KR102275471B1 (en)
CN (2) CN111304504A (en)
BR (1) BR112015004503B1 (en)
CA (1) CA2883268C (en)
IN (1) IN2015DN01751A (en)
TW (1) TWI640638B (en)
WO (1) WO2014036262A1 (en)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HK1200881A1 (en) 2012-06-26 2015-08-14 百多力股份公司 Magnesium alloy, method for the production thereof and use thereof
RU2015101291A (en) 2012-06-26 2016-08-10 Биотроник Аг MAGNESIUM ALLOY, METHOD OF ITS PRODUCTION AND USE
US10358709B2 (en) 2012-06-26 2019-07-23 Biotronik Ag Magnesium-zinc-calcium alloy, method for production thereof, and use thereof
AU2013283433A1 (en) 2012-06-26 2014-10-09 Biotronik Ag Magnesium-zinc-calcium alloy, method for production thereof, and use thereof
US9469889B2 (en) 2012-08-31 2016-10-18 DePuy Synthes Products, Inc. Ultrapure magnesium alloy with adjustable degradation rate
US10478529B2 (en) 2013-03-14 2019-11-19 DePuy Synthes Products, Inc. Magnesium alloy with adjustable degradation rate
US9593397B2 (en) 2013-03-14 2017-03-14 DePuy Synthes Products, Inc. Magnesium alloy with adjustable degradation rate
US20160206788A1 (en) * 2013-06-12 2016-07-21 The Regents Of The University Of California Biomimetic interfaces for biodegradable metallic implants
WO2016033312A1 (en) * 2014-08-27 2016-03-03 University Of Pittsburgh-Of The Commonwealth System Of Higher Education Magnesium enhanced/induced bone formation
TWI610651B (en) * 2014-11-20 2018-01-11 財團法人金屬工業研究發展中心 A magnesium alloy sewing nail
CN105568103A (en) * 2016-01-04 2016-05-11 青岛工学院 Degradable biomedical magnesium alloy
CN107227422A (en) * 2016-03-25 2017-10-03 武汉理工大学 A kind of high intensity saline soluble magnesium alloy materials and preparation method thereof
KR20170115429A (en) 2016-04-07 2017-10-17 랩앤피플주식회사 Micro needle Using the Bioabsorbable Metal
WO2017176077A1 (en) * 2016-04-07 2017-10-12 랩앤피플주식회사 Microneedle using biodegradable metal
KR101888091B1 (en) * 2016-10-31 2018-08-14 유앤아이 주식회사 Biodegradable Mg alloy and method of fabricating the same
WO2018109947A1 (en) * 2016-12-16 2018-06-21 三協立山株式会社 Method for producing magnesium alloy, and magnesium alloy
CN107190192B (en) * 2017-07-10 2018-10-02 太原理工大学 A kind of absorbable biological medicinal high-strength anticorrosion magnesium alloy material and preparation method thereof
CN107236886B (en) * 2017-07-10 2018-09-07 太原理工大学 A kind of polynary Mg-Zn-Y-Ca-Zr alloys of medical degradable high-strength anticorrosion and preparation method thereof
CN107523732B (en) * 2017-08-15 2019-04-05 太原科技大学 One kind magnesium alloy of fast degradation containing Na and preparation method thereof
CN108425051A (en) * 2018-03-29 2018-08-21 江苏理工学院 A kind of bio-medical Mg-Sn-Zn-Ca magnesium alloys and preparation method thereof
CN109112377B (en) * 2018-11-09 2020-06-02 吉林大学 Corrosion-resistant biomedical magnesium alloy and preparation method and application thereof
CN110438380B (en) * 2019-08-13 2021-02-26 中南大学 A kind of heat-resistant and flame-retardant magnesium alloy and deformation heat treatment method thereof
WO2021040988A1 (en) * 2019-08-26 2021-03-04 Ohio State Innovation Foundation Magnesium alloy based objects and methods of making and use thereof
CN110604632A (en) * 2019-10-21 2019-12-24 中国人民解放军南部战区海军第一医院 Biodegradable cosmetic pulling line and preparation method thereof
CN111388764B (en) * 2020-04-03 2024-06-04 北京联合大学 Degradable metal anastomosis nail and preparation method thereof
US20230201416A1 (en) * 2020-04-21 2023-06-29 National University Corporation Kumamoto University Implant magnesium alloy, bone fixture, method of manufacturing implant magnesium alloy, and method of manufacturing bone fixture device
EP4023263B1 (en) 2020-12-31 2024-03-27 Bioretec Oy An implant comprising magnesium alloy and a method for preparing thereof
JP2021079133A (en) * 2021-02-10 2021-05-27 キュースリー メディカル デヴァイシズ リミテッドＱ３ Ｍｅｄｉｃａｌ Ｄｅｖｉｃｅｓ Ｌｉｍｉｔｅｄ Biodegradable supporting device

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3320055A (en) 1964-08-19 1967-05-16 Dow Chemical Co Magnesium-base alloy
AU2002950563A0 (en) * 2002-08-02 2002-09-12 Commonwealth Scientific And Industrial Research Organisation Age-Hardenable, Zinc-Containing Magnesium Alloys
CN1743486A (en) 2004-08-31 2006-03-08 唐智荣 Alloy as magnesium element as matrix and its use as bone-fracture internal fixer
CN100400114C (en) * 2005-04-30 2008-07-09 中国科学院金属研究所 Biomedical implant material with controllable degradation rate and its application
US8034101B2 (en) 2005-11-16 2011-10-11 National Institute For Materials Science Magnesium-based biodegradable metallic material
CN100368028C (en) 2005-12-22 2008-02-13 上海交通大学 Bioabsorbable Mg-Zn Binary Magnesium Alloy Materials
CN1792383A (en) * 2005-12-22 2006-06-28 上海交通大学 Bio-absorbable Mg-Zn-Ca three-elements magnesium alloy material
DE102006015457A1 (en) 2006-03-31 2007-10-04 Biotronik Vi Patent Ag Magnesium alloy and related manufacturing process
CN102512711A (en) 2006-09-22 2012-06-27 友和安股份公司 Implants comprising biodegradable metals and method for manufacturing the same
KR101289122B1 (en) 2008-03-18 2013-07-23 한국보건산업진흥원 COMPLEX IMPLANTS INFILTERATED WITH BIODEGRADABLE Mg(ALLOYS) INSIDE POROUS STRUCTURAL MATERIALS AND METHOD FOR MANUFACTURING THE SAME
JP5467294B2 (en) 2008-06-05 2014-04-09 独立行政法人産業技術総合研究所 Easy-formable magnesium alloy sheet and method for producing the same
BRPI0912151A2 (en) 2008-06-06 2018-11-06 Synthes Gmbh resorbable magnesium alloy
CN101629260A (en) 2008-07-18 2010-01-20 中国科学院金属研究所 Medical absorbable Mg-Zn-Mn-Ca magnesium alloy
ES2712548T3 (en) 2009-04-22 2019-05-13 U & I Corp Biodegradable implant and procedure to make the same
JP5593812B2 (en) * 2009-04-30 2014-09-24 Ｊｆｅスチール株式会社 Zn-Mg plated steel sheet and method for producing the same
CN101658691B (en) 2009-07-31 2013-03-13 哈尔滨工业大学 Method for plastically manufacturing high-purity magnesium alloy absorbable stent
CN102639158A (en) 2009-12-07 2012-08-15 友和安股份公司 Implant
WO2011071304A2 (en) 2009-12-07 2011-06-16 유앤아이 주식회사 Magnesium alloy
AT510087B1 (en) 2010-07-06 2012-05-15 Ait Austrian Institute Of Technology Gmbh MAGNESIUM ALLOY
CN101899600B (en) 2010-08-13 2012-04-25 上海交通大学 Orthopedic magnesium alloy implant material and preparation method thereof
JP5720926B2 (en) 2010-10-12 2015-05-20 住友電気工業株式会社 Magnesium alloy wire, bolt, nut and washer
US8956403B2 (en) * 2010-10-18 2015-02-17 Boston Scientific Scimed, Inc. Medical implant including a magnesium-based tie layer
EP2804964B1 (en) 2012-01-19 2019-07-31 ETH Zuerich Process and apparatus for vacuum distillation of high-purity magnesium
AU2013283433A1 (en) 2012-06-26 2014-10-09 Biotronik Ag Magnesium-zinc-calcium alloy, method for production thereof, and use thereof
US10358709B2 (en) 2012-06-26 2019-07-23 Biotronik Ag Magnesium-zinc-calcium alloy, method for production thereof, and use thereof
US9469889B2 (en) * 2012-08-31 2016-10-18 DePuy Synthes Products, Inc. Ultrapure magnesium alloy with adjustable degradation rate
US9593397B2 (en) 2013-03-14 2017-03-14 DePuy Synthes Products, Inc. Magnesium alloy with adjustable degradation rate
US10478529B2 (en) 2013-03-14 2019-11-19 DePuy Synthes Products, Inc. Magnesium alloy with adjustable degradation rate

Also Published As

Publication number Publication date
US9469889B2 (en) 2016-10-18
BR112015004503B1 (en) 2021-03-02
CN104755644A (en) 2015-07-01
CA2883268C (en) 2021-01-05
BR112015004503A2 (en) 2017-07-04
US10213522B2 (en) 2019-02-26
CN111304504A (en) 2020-06-19
CA2883268A1 (en) 2014-03-06
JP2019049056A (en) 2019-03-28
JP6752575B2 (en) 2020-09-09
US20170000925A1 (en) 2017-01-05
KR102275471B1 (en) 2021-07-13
WO2014036262A1 (en) 2014-03-06
TWI640638B (en) 2018-11-11
JP2015532685A (en) 2015-11-12
KR20150050586A (en) 2015-05-08
US20140065009A1 (en) 2014-03-06
TW201422822A (en) 2014-06-16
EP2890824A1 (en) 2015-07-08
EP2890824B1 (en) 2019-04-17

Similar Documents

Publication Publication Date Title
IN2015DN01751A (en)
PH12016500216A1 (en) Stable pharmaceutical composition and methods of using same
MX2013002422A (en) Salts of lorcaserin with optically active acids.
HK1204272A1 (en) Methods of treating pediatric metabolic syndrome
EP4421181A3 (en) Non-natural microbial organisms with improved energetic efficiency
MX2022010507A (en) Methods of reducing the risk of a cardiovascular event in a subject on statin therapy.
EP3257943A3 (en) Methods and vectors for cell immortalisation
MX365135B (en) Bone implant made of at least two different absorbable and biodegradable materials adapted to be combined as hybrid or composite material.
MY182932A (en) Plated steel sheet with quasicrystal
BR112013011259A2 (en) treatment conditions associated with increased eotaxin level with 25-hydroxyvitamin d3
TN2012000507A1 (en) Enteric tablet
MY173321A (en) Use of nutritional compositions including lactoferrin in stimulating immune cells
CY1121268T1 (en) IMMUNE STIMULATING COMPOSITION INCLUDING ARONIA SP EXTRACT. IN COMBINATION WITH MOON
PH12014500859A1 (en) Pharmaceutical compositions comprising dgla and/or 15-hetre and methods of use thereof
MX2013005917A (en) Self-locking screw.
MX2015007678A (en) Transmucosal delivery of glatiramer acetate.
MX2013001793A (en) Product for the upper gastric sphere.
MX2013006356A (en) Filling composition comprising hydrolyzed whole grain.
MX2010008280A (en) Composition for stimulating natural killer cell activity.
MX2015007794A (en) Oral transmucosal delivery of glatiramer acetate.
MX2016007490A (en) Nutrition, exercise and cognitive development.
MX2011007222A (en) Nutritional composition for infants.
IN2014MN01551A (en)
MY163074A (en) Formulations comprising methylthioninium chloride
CA2836488C (en) Methods for treating obesity and/or metabolic syndrome