IS2261B - Process for the preparation of 5-cyanothalide - Google Patents
Process for the preparation of 5-cyanothalideInfo
- Publication number
- IS2261B IS2261B IS5952A IS5952A IS2261B IS 2261 B IS2261 B IS 2261B IS 5952 A IS5952 A IS 5952A IS 5952 A IS5952 A IS 5952A IS 2261 B IS2261 B IS 2261B
- Authority
- IS
- Iceland
- Prior art keywords
- cyanothalide
- preparation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/87—Benzo [c] furans; Hydrogenated benzo [c] furans
- C07D307/88—Benzo [c] furans; Hydrogenated benzo [c] furans with one oxygen atom directly attached in position 1 or 3
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Indole Compounds (AREA)
- Furan Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DKPA199801718 | 1998-12-23 | ||
| PCT/DK1999/000728 WO2000039112A1 (en) | 1998-12-23 | 1999-12-22 | Method for the preparation of 5-cyanophthalide |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IS5952A IS5952A (en) | 2001-05-22 |
| IS2261B true IS2261B (en) | 2007-06-15 |
Family
ID=8107494
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IS5952A IS2261B (en) | 1998-12-23 | 2001-05-22 | Process for the preparation of 5-cyanothalide |
Country Status (31)
| Country | Link |
|---|---|
| US (1) | US6392060B2 (en) |
| EP (1) | EP1140886B1 (en) |
| JP (1) | JP2002533450A (en) |
| KR (1) | KR100454008B1 (en) |
| CN (1) | CN1149208C (en) |
| AR (1) | AR019791A1 (en) |
| AT (1) | ATE236145T1 (en) |
| AU (1) | AU764161B2 (en) |
| BG (1) | BG64986B1 (en) |
| BR (1) | BR9916955A (en) |
| CA (1) | CA2356188C (en) |
| CZ (1) | CZ300408B6 (en) |
| DE (1) | DE69906580T2 (en) |
| DK (1) | DK1140886T3 (en) |
| EA (1) | EA003057B1 (en) |
| ES (1) | ES2195644T3 (en) |
| HK (1) | HK1043130B (en) |
| HU (1) | HUP0104856A3 (en) |
| IL (1) | IL143422A0 (en) |
| IS (1) | IS2261B (en) |
| IT (1) | IT1315269B1 (en) |
| NO (1) | NO326516B1 (en) |
| NZ (1) | NZ512073A (en) |
| PL (1) | PL203275B1 (en) |
| PT (1) | PT1140886E (en) |
| SI (1) | SI1140886T1 (en) |
| SK (1) | SK285530B6 (en) |
| TR (1) | TR200101796T2 (en) |
| UA (1) | UA70979C2 (en) |
| WO (1) | WO2000039112A1 (en) |
| ZA (1) | ZA200104262B (en) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2189502T3 (en) | 1998-10-20 | 2003-07-01 | Lundbeck & Co As H | METHOD FOR THE PREVENTION OF CITALOPRAM. |
| IL143422A0 (en) | 1998-12-23 | 2002-04-21 | Lundbeck & Co As H | Method for the preparation of 5-cyanophthalide |
| AR022329A1 (en) * | 1999-01-29 | 2002-09-04 | Lundbeck & Co As H | METHOD FOR THE PREPARATION OF 5-CYANOFTALIDE |
| DK1173431T4 (en) | 1999-04-14 | 2010-01-04 | Lundbeck & Co As H | Process for the preparation of citalopram |
| ITMI991581A1 (en) * | 1999-06-25 | 2001-01-15 | Lundbeck & Co As H | METHOD FOR THE PREPARATION OF CITALOPRAM |
| ITMI991579A1 (en) | 1999-06-25 | 2001-01-15 | Lundbeck & Co As H | METHOD FOR THE PREPARATION OF CITALOPRAM |
| CH692421A5 (en) | 1999-10-25 | 2002-06-14 | Lundbeck & Co As H | Preparation of citalopram as antidepressant drug and for treating dementia and cerebrovascular disorders comprises reaction of a new intermediate with 3-(N,N-dimethylamino)propyl magnesium halide |
| DK1298124T3 (en) | 1999-10-25 | 2007-07-09 | Lundbeck & Co As H | Process for the preparation of citalopram |
| AR026063A1 (en) | 1999-11-01 | 2002-12-26 | Lundbeck & Co As H | METHOD FOR THE PREPARATION OF 5-CARBOXIFTALIDA. |
| JP2003519136A (en) | 1999-12-28 | 2003-06-17 | ハー・ルンドベック・アクチエゼルスカベット | Method for producing citalopram |
| DK1246813T3 (en) | 1999-12-30 | 2004-03-01 | Lundbeck & Co As H | Process for Preparing Citalopram |
| AU3033700A (en) | 2000-01-14 | 2001-07-24 | H. Lundbeck A/S | Method for the preparation of 5-cyanophthalide |
| FR2805812A1 (en) | 2000-02-24 | 2001-09-07 | Lundbeck & Co As H | PROCESS FOR THE PREPARATION OF CITALOPRAM |
| IES20010157A2 (en) | 2000-03-03 | 2002-03-06 | Lundbeck & Co As H | Method for the preparation of citalopram |
| KR20020080485A (en) | 2000-03-13 | 2002-10-23 | 하. 룬트벡 아크티에 셀스카브 | Stepwise alkylation of 5-substituted 1-(4-fluorophenyl)-1,3-dihydroisobenzo furans |
| AU2001242298A1 (en) | 2000-03-13 | 2001-09-24 | H Lunbeck A/S | Method for the preparation of citalopram |
| NL1017500C1 (en) | 2000-03-13 | 2001-04-26 | Lundbeck & Co As H | Process for the preparation of Citalopram. |
| ES2214400T3 (en) | 2000-03-14 | 2004-09-16 | H. Lundbeck A/S | METHOD FOR THE PREPARATION OF CITALOPRAM. |
| DE10190485T1 (en) * | 2000-03-16 | 2002-03-21 | Lundbeck & Co As H | Process for the preparation of 5-cyano-1- (4-fluorophenyl) -1,3-dihydroisobenzofurans |
| AR032455A1 (en) | 2000-05-12 | 2003-11-12 | Lundbeck & Co As H | METHOD FOR THE PREPARATION OF CITALOPRAM, AN INTERMEDIARY EMPLOYED IN THE METHOD, A METHOD FOR THE PREPARATION OF THE INTERMEDIARY EMPLOYED IN THE METHOD AND PHARMACEUTICAL COMPOSITION ANTIDEPRESSIVE |
| CA2354877C (en) * | 2000-08-18 | 2006-05-02 | H. Lundbeck A/S | Method for the preparation of citalopram |
| CA2360303C (en) | 2000-12-22 | 2003-08-12 | Marco Villa | Process for the preparation of pure citalopram |
| SK284418B6 (en) | 2000-12-28 | 2005-04-01 | H. Lundbeck A/S | Process for producing citalopram |
| EP1321464A1 (en) * | 2001-12-21 | 2003-06-25 | ICROM S.p.A. | Process for the preparation of 5-cyanophthalide and intermediates useful therein |
| CN1761659A (en) | 2003-03-21 | 2006-04-19 | H·隆德贝克有限公司 | Intermediates for the preparation of citalopram and escitalopram |
| AU2003223105A1 (en) * | 2003-03-24 | 2004-10-18 | Hetero Drugs Limited | Novel crystalline forms of (s)-citalopram oxalate |
| EP1777221A1 (en) | 2005-10-14 | 2007-04-25 | Adorkem Technology SpA | Process for the preparation of 5-cyanophthalide starting from 5-carboxyphthalide |
| CN119775242B (en) * | 2024-12-31 | 2025-08-15 | 内蒙古源宏精细化工有限公司 | Method for synthesizing 5-cyanophthalide |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1143703A (en) | 1965-03-18 | |||
| GB1526331A (en) | 1976-01-14 | 1978-09-27 | Kefalas As | Phthalanes |
| GB8419963D0 (en) | 1984-08-06 | 1984-09-12 | Lundbeck & Co As H | Intermediate compound and method |
| GB8814057D0 (en) | 1988-06-14 | 1988-07-20 | Lundbeck & Co As H | New enantiomers & their isolation |
| DK213290D0 (en) | 1990-09-06 | 1990-09-06 | Lundbeck & Co As H | TREATMENT OF CEREBROVASCULAR DISORDERS |
| DE19626659A1 (en) | 1996-07-03 | 1998-01-08 | Basf Ag | Process for the production of phthalides |
| DE19627697A1 (en) | 1996-07-10 | 1998-01-15 | Basf Ag | Process for the production of phthalides |
| ZA9711376B (en) | 1996-12-20 | 1998-07-21 | Lundbeck & Co As H | Indole or dihydroindole derivatives |
| SK283309B6 (en) * | 1997-07-08 | 2003-05-02 | H. Lundbeck A/S | Method for the preparation of citalopram and intermediates |
| UA62985C2 (en) | 1997-11-10 | 2004-01-15 | Lunnbeck As H | A method for the preparation of citalopram |
| DK1042310T3 (en) | 1997-11-11 | 2002-12-02 | Lundbeck & Co As H | Process for the preparation of citalopram |
| ES2189502T3 (en) | 1998-10-20 | 2003-07-01 | Lundbeck & Co As H | METHOD FOR THE PREVENTION OF CITALOPRAM. |
| IL143422A0 (en) | 1998-12-23 | 2002-04-21 | Lundbeck & Co As H | Method for the preparation of 5-cyanophthalide |
| AR022329A1 (en) | 1999-01-29 | 2002-09-04 | Lundbeck & Co As H | METHOD FOR THE PREPARATION OF 5-CYANOFTALIDE |
| DK1173431T4 (en) | 1999-04-14 | 2010-01-04 | Lundbeck & Co As H | Process for the preparation of citalopram |
| ITMI991579A1 (en) | 1999-06-25 | 2001-01-15 | Lundbeck & Co As H | METHOD FOR THE PREPARATION OF CITALOPRAM |
| ITMI991581A1 (en) | 1999-06-25 | 2001-01-15 | Lundbeck & Co As H | METHOD FOR THE PREPARATION OF CITALOPRAM |
| CH692421A5 (en) | 1999-10-25 | 2002-06-14 | Lundbeck & Co As H | Preparation of citalopram as antidepressant drug and for treating dementia and cerebrovascular disorders comprises reaction of a new intermediate with 3-(N,N-dimethylamino)propyl magnesium halide |
| US6310222B1 (en) | 1999-11-01 | 2001-10-30 | Sumika Fine Chemicals Co., Ltd. | Production method of 5-phthalancarbonitrile compound, intermediate therefor and production method of the intermediate |
-
1999
- 1999-12-22 IL IL14342299A patent/IL143422A0/en not_active IP Right Cessation
- 1999-12-22 EP EP99960958A patent/EP1140886B1/en not_active Expired - Lifetime
- 1999-12-22 HK HK02105040.7A patent/HK1043130B/en not_active IP Right Cessation
- 1999-12-22 PT PT99960958T patent/PT1140886E/en unknown
- 1999-12-22 JP JP2000591023A patent/JP2002533450A/en active Pending
- 1999-12-22 CN CNB998150002A patent/CN1149208C/en not_active Expired - Fee Related
- 1999-12-22 CA CA002356188A patent/CA2356188C/en not_active Expired - Fee Related
- 1999-12-22 AU AU17742/00A patent/AU764161B2/en not_active Ceased
- 1999-12-22 DE DE69906580T patent/DE69906580T2/en not_active Expired - Lifetime
- 1999-12-22 HU HU0104856A patent/HUP0104856A3/en unknown
- 1999-12-22 DK DK99960958T patent/DK1140886T3/en active
- 1999-12-22 SI SI9930278T patent/SI1140886T1/en unknown
- 1999-12-22 CZ CZ20012335A patent/CZ300408B6/en not_active IP Right Cessation
- 1999-12-22 AT AT99960958T patent/ATE236145T1/en not_active IP Right Cessation
- 1999-12-22 SK SK896-2001A patent/SK285530B6/en unknown
- 1999-12-22 KR KR10-2001-7007686A patent/KR100454008B1/en not_active Expired - Fee Related
- 1999-12-22 PL PL348608A patent/PL203275B1/en not_active IP Right Cessation
- 1999-12-22 UA UA2001064498A patent/UA70979C2/en unknown
- 1999-12-22 EA EA200100696A patent/EA003057B1/en not_active IP Right Cessation
- 1999-12-22 BR BR9916955-0A patent/BR9916955A/en not_active IP Right Cessation
- 1999-12-22 ES ES99960958T patent/ES2195644T3/en not_active Expired - Lifetime
- 1999-12-22 WO PCT/DK1999/000728 patent/WO2000039112A1/en not_active Ceased
- 1999-12-22 TR TR2001/01796T patent/TR200101796T2/en unknown
- 1999-12-22 NZ NZ512073A patent/NZ512073A/en not_active IP Right Cessation
- 1999-12-23 IT IT1999MI002696A patent/IT1315269B1/en active
- 1999-12-23 AR ARP990106726A patent/AR019791A1/en active IP Right Grant
-
2001
- 2001-05-22 IS IS5952A patent/IS2261B/en unknown
- 2001-05-24 ZA ZA200104262A patent/ZA200104262B/en unknown
- 2001-06-22 US US09/888,067 patent/US6392060B2/en not_active Expired - Fee Related
- 2001-06-22 NO NO20013150A patent/NO326516B1/en not_active IP Right Cessation
- 2001-06-27 BG BG105655A patent/BG64986B1/en unknown
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