IS4152A - Water-soluble Camptothecin derivatives and their method of production - Google Patents
Water-soluble Camptothecin derivatives and their method of productionInfo
- Publication number
- IS4152A IS4152A IS4152A IS4152A IS4152A IS 4152 A IS4152 A IS 4152A IS 4152 A IS4152 A IS 4152A IS 4152 A IS4152 A IS 4152A IS 4152 A IS4152 A IS 4152A
- Authority
- IS
- Iceland
- Prior art keywords
- production
- water
- camptothecin derivatives
- soluble camptothecin
- soluble
- Prior art date
Links
- VSJKWCGYPAHWDS-FQEVSTJZSA-N camptothecin Chemical class C1=CC=C2C=C(CN3C4=CC5=C(C3=O)COC(=O)[C@]5(O)CC)C4=NC2=C1 VSJKWCGYPAHWDS-FQEVSTJZSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
- C07D317/62—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to atoms of the carbocyclic ring
- C07D317/66—Nitrogen atoms not forming part of a nitro radical
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
- C07D319/14—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
- C07D319/16—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D319/18—Ethylenedioxybenzenes, not substituted on the hetero ring
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US5458593A | 1993-04-29 | 1993-04-29 | |
| US8104293A | 1993-06-22 | 1993-06-22 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IS4152A true IS4152A (en) | 1994-10-30 |
Family
ID=26733234
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IS4152A IS4152A (en) | 1993-04-29 | 1994-04-25 | Water-soluble Camptothecin derivatives and their method of production |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP0696285A1 (en) |
| JP (1) | JPH08509740A (en) |
| AP (1) | AP9400638A0 (en) |
| AU (1) | AU6777194A (en) |
| CA (1) | CA2161681A1 (en) |
| IL (1) | IL109470A0 (en) |
| IS (1) | IS4152A (en) |
| MY (1) | MY141374A (en) |
| PE (1) | PE52894A1 (en) |
| WO (1) | WO1994025466A1 (en) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6504029B1 (en) * | 1995-04-10 | 2003-01-07 | Daiichi Pharmaceutical Co., Ltd. | Condensed-hexacyclic compounds and a process therefor |
| US5663177A (en) * | 1995-05-31 | 1997-09-02 | Smithkline Beecham Corporation | Water soluble camptothecin analogs |
| SG104284A1 (en) * | 1996-10-30 | 2004-06-21 | Tanabe Seiyaku Co | S type 2-substituted hydroxy-2-indolidinylbutyric ester compounds and process for preparation thereof |
| US6559309B2 (en) | 1996-11-01 | 2003-05-06 | Osi Pharmaceuticals, Inc. | Preparation of a camptothecin derivative by intramolecular cyclisation |
| US6046209A (en) * | 1997-05-27 | 2000-04-04 | Smithkline Beecham Corporation | Water soluble camptothecin analogs |
| IN189180B (en) * | 1997-07-09 | 2003-01-04 | Chong Kun Dang Corp | |
| US6858598B1 (en) | 1998-12-23 | 2005-02-22 | G. D. Searle & Co. | Method of using a matrix metalloproteinase inhibitor and one or more antineoplastic agents as a combination therapy in the treatment of neoplasia |
| US6833373B1 (en) | 1998-12-23 | 2004-12-21 | G.D. Searle & Co. | Method of using an integrin antagonist and one or more antineoplastic agents as a combination therapy in the treatment of neoplasia |
| US6288072B1 (en) * | 1999-12-29 | 2001-09-11 | Monroe E. Wall | Camptothecin β-alanine esters with topoisomerase I inhibition |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK0418099T3 (en) * | 1989-09-15 | 2002-04-02 | Res Triangle Inst | Process for Preparation of 10,11-Methylenedioxy-20 (RS) Camptothecin and 10,11-Methylenedioxy-20 (S) Camptothecin Analogs |
| ATE136898T1 (en) * | 1991-10-29 | 1996-05-15 | Glaxo Wellcome Inc | WATER SOLUBLE CAMPTOTHECINE DERIVATIVES |
| CA2087898A1 (en) * | 1992-01-24 | 1993-07-25 | Hiroshi Akimoto | Condensed heterocyclic compounds, their production and use |
-
1994
- 1994-04-25 IS IS4152A patent/IS4152A/en unknown
- 1994-04-27 MY MYPI94001039A patent/MY141374A/en unknown
- 1994-04-27 PE PE1994241061A patent/PE52894A1/en not_active Application Discontinuation
- 1994-04-28 WO PCT/US1994/004681 patent/WO1994025466A1/en not_active Ceased
- 1994-04-28 EP EP94915931A patent/EP0696285A1/en not_active Withdrawn
- 1994-04-28 CA CA002161681A patent/CA2161681A1/en not_active Abandoned
- 1994-04-28 JP JP6524540A patent/JPH08509740A/en active Pending
- 1994-04-28 AU AU67771/94A patent/AU6777194A/en not_active Abandoned
- 1994-04-28 AP APAP/P/1994/000638A patent/AP9400638A0/en unknown
- 1994-04-28 IL IL10947094A patent/IL109470A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JPH08509740A (en) | 1996-10-15 |
| AP9400638A0 (en) | 1995-10-28 |
| AU6777194A (en) | 1994-11-21 |
| MY141374A (en) | 2010-04-16 |
| CA2161681A1 (en) | 1994-11-10 |
| PE52894A1 (en) | 1995-01-06 |
| WO1994025466A1 (en) | 1994-11-10 |
| EP0696285A1 (en) | 1996-02-14 |
| IL109470A0 (en) | 1994-07-31 |
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