IS4181A - Fucosylated glycosides that inhibit the adhesion of bacteria - Google Patents

Fucosylated glycosides that inhibit the adhesion of bacteria

Info

Publication number
IS4181A
IS4181A IS4181A IS4181A IS4181A IS 4181 A IS4181 A IS 4181A IS 4181 A IS4181 A IS 4181A IS 4181 A IS4181 A IS 4181A IS 4181 A IS4181 A IS 4181A
Authority
IS
Iceland
Prior art keywords
fucosylated
glycosides
bacteria
inhibit
adhesion
Prior art date
Application number
IS4181A
Other languages
Icelandic (is)
Inventor
Ingeborg Eklind Karen
Roland Lönn Hans
Ulla Edit Tidén Anna-Karin
Original Assignee
Ab Astra
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ab Astra filed Critical Ab Astra
Publication of IS4181A publication Critical patent/IS4181A/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/58Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. poly[meth]acrylate, polyacrylamide, polystyrene, polyvinylpyrrolidone, polyvinylalcohol or polystyrene sulfonic acid resin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IS4181A 1993-06-25 1994-06-22 Fucosylated glycosides that inhibit the adhesion of bacteria IS4181A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK93761A DK76193D0 (en) 1993-06-25 1993-06-25 CARBOHYDRATE DERIVATIVES

Publications (1)

Publication Number Publication Date
IS4181A true IS4181A (en) 1994-12-26

Family

ID=8097261

Family Applications (1)

Application Number Title Priority Date Filing Date
IS4181A IS4181A (en) 1993-06-25 1994-06-22 Fucosylated glycosides that inhibit the adhesion of bacteria

Country Status (9)

Country Link
EP (1) EP0706528A1 (en)
JP (1) JPH08512026A (en)
AU (1) AU7089194A (en)
CA (1) CA2164961A1 (en)
DK (1) DK76193D0 (en)
IL (1) IL110074A0 (en)
IS (1) IS4181A (en)
LT (1) LT3446B (en)
WO (1) WO1995000527A1 (en)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6204431B1 (en) 1994-03-09 2001-03-20 Abbott Laboratories Transgenic non-human mammals expressing heterologous glycosyltransferase DNA sequences produce oligosaccharides and glycoproteins in their milk
JPH1160590A (en) * 1997-08-22 1999-03-02 Yakult Honsha Co Ltd Oligofucose derivative or oligorhamnose derivative and method for producing the same
SE9901007D0 (en) * 1999-03-19 1999-03-19 Thomas Boren Use of fucosylated sialylated N-acetyl lactosamine carbohydrate structures for inhibition of bacterial adherence
JP5175190B2 (en) * 2005-08-09 2013-04-03 グリコミメティクス, インコーポレイテッド Pseudomonas-derived PA-IL lectin, PA-IIL lectin or a glycomimetic inhibitor of both lectins
US8921328B2 (en) 2010-09-14 2014-12-30 Glycomimetics, Inc. E-selectin antagonists
SI2794626T1 (en) 2011-12-22 2018-02-28 Glycomimetics, Inc. E-selectin antagonist compounds
EP2692740A1 (en) * 2012-07-30 2014-02-05 Le Centre National De La Recherche Scientifique Glycan compositions, processes for preparing the same and their uses as a drug
LT2928476T (en) 2012-12-07 2018-05-25 Glycomimetics, Inc. Compounds, compositions and methods using e-selectin antagonists for mobilization of hematopoietic cells
CA2893927A1 (en) * 2013-01-31 2014-08-07 Pioneer Hi-Bred International, Inc. Synthetic lipochitooligosaccharides for improvement of plant growth and yield
US10086054B2 (en) * 2013-06-26 2018-10-02 Academia Sinica RM2 antigens and use thereof
HUE045542T2 (en) 2014-12-03 2019-12-30 Glycomimetics Inc Heterobifunctional inhibitors of e-selectins and cxcr4 chemokine receptors
WO2017127422A1 (en) 2016-01-22 2017-07-27 Glycomimetics, Inc. Glycomimetic inhibitors of pa-il and pa-iil lectins
WO2017151708A1 (en) 2016-03-02 2017-09-08 Glycomimetics, Inc. Methods for the treatment and/or prevention of cardiovescular disease by inhibition of e-selectin
EP3497131B1 (en) 2016-08-08 2022-03-09 GlycoMimetics, Inc. Combination of t-cell checkpoint inhibitors with inhibitors of e-selectin or cxcr4, or with heterobifunctional inhibitors of both e-selectin and cxcr4.
CA3037850A1 (en) 2016-10-07 2018-04-12 Glycomimetics, Inc. Highly potent multimeric e-selectin antagonists
CA3054605A1 (en) 2017-03-15 2018-09-20 Glycomimetics, Inc. Galactopyranosyl-cyclohexyl derivatives as e-selectin antagonists
EP3717013A1 (en) 2017-11-30 2020-10-07 GlycoMimetics, Inc. Methods of mobilizing marrow infiltrating lymphocytes and uses thereof
EP3732186A1 (en) 2017-12-29 2020-11-04 GlycoMimetics, Inc. Heterobifunctional inhibitors of e-selectin and galectin-3
US11707474B2 (en) 2018-03-05 2023-07-25 Glycomimetics, Inc. Methods for treating acute myeloid leukemia and related conditions
BR112021003156A2 (en) 2018-08-23 2021-05-11 Seagen, Inc. composition, antibody that binds to human tigi, pharmaceutical formulation, isolated polynucleotide, vector, host cell, methods for producing an antibody that binds to human tigi and fucosylated antibodies that bind to tigi, and for the treatment of cancer , and, kit.
US11845771B2 (en) 2018-12-27 2023-12-19 Glycomimetics, Inc. Heterobifunctional inhibitors of E-selectin and galectin-3
CA3122321A1 (en) 2018-12-27 2020-07-02 Glycomimetics, Inc. Galectin-3 inhibiting c-glycosides

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1603609A (en) * 1977-04-14 1981-11-25 Chembiomed Ltd O-protected 2-azido-2-deoxy-glycosyl nitrates
FR2509313A1 (en) * 1981-07-08 1983-01-14 Choay Sa 3-FUCOSYL-N-ACETYL LACTOSAMINE DERIVATIVES, THEIR PREPARATION AND THEIR BIOLOGICAL APPLICATIONS
DE3220427A1 (en) * 1982-05-29 1983-12-01 Behringwerke Ag, 3550 Marburg SS-D-GALACTOSE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE
DK17685D0 (en) * 1985-01-14 1985-01-14 Hans Goeran Magnusson glycoside
AU609999B2 (en) * 1988-06-21 1991-05-09 Marion Laboratories, Inc. Bismuth (phosph/sulf)ated saccharides

Also Published As

Publication number Publication date
LTIP1978A (en) 1995-01-31
AU7089194A (en) 1995-01-17
LT3446B (en) 1995-10-25
IL110074A0 (en) 1994-10-07
EP0706528A1 (en) 1996-04-17
JPH08512026A (en) 1996-12-17
DK76193D0 (en) 1993-06-25
CA2164961A1 (en) 1995-01-05
WO1995000527A1 (en) 1995-01-05

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