IS4627A - Lyfjablanda sem samanstendur af hindra fyrir proteinkljúfandi hvata og monoglycerid - Google Patents

Lyfjablanda sem samanstendur af hindra fyrir proteinkljúfandi hvata og monoglycerid

Info

Publication number: IS4627A
Authority: IS; Iceland
Prior art keywords: monoglyceride; inhibitor; pharmaceutical composition; protein cleavage; cleavage catalyst
Prior art date: 1995-06-06

Application number

IS4627A

Other languages

English (en)

Other versions

IS2661B (is

Inventor

Ann Bailey Carole

Josephine Ferdinando Christine

Shah Navnit

Original Assignee

F. Hoffmann-La Roche Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-06-06

Filing date

1997-12-04

Publication date

1997-12-04

1996-05-07 Priority claimed from US08/616,233 external-priority patent/US6008228A/en

1997-12-04 Application filed by F. Hoffmann-La Roche Ag filed Critical F. Hoffmann-La Roche Ag

1997-12-04 Publication of IS4627A publication Critical patent/IS4627A/is

2010-08-15 Publication of IS2661B publication Critical patent/IS2661B/is

Links

LDVVTQMJQSCDMK-UHFFFAOYSA-N 1,3-dihydroxypropan-2-yl formate Chemical compound OCC(CO)OC=O LDVVTQMJQSCDMK-UHFFFAOYSA-N 0.000 title 1
239000003054 catalyst Substances 0.000 title 1
239000003112 inhibitor Substances 0.000 title 1
239000008194 pharmaceutical composition Substances 0.000 title 1
230000007026 protein scission Effects 0.000 title 1
239000000203 mixture Substances 0.000 abstract 2
229940019748 antifibrinolytic proteinase inhibitors Drugs 0.000 abstract 1
OGBUMNBNEWYMNJ-UHFFFAOYSA-N batilol Chemical class CCCCCCCCCCCCCCCCCCOCC(O)CO OGBUMNBNEWYMNJ-UHFFFAOYSA-N 0.000 abstract 1
239000003937 drug carrier Substances 0.000 abstract 1
150000004667 medium chain fatty acids Chemical class 0.000 abstract 1
239000000137 peptide hydrolase inhibitor Substances 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/472—Non-condensed isoquinolines, e.g. papaverine
- A61K31/4725—Non-condensed isoquinolines, e.g. papaverine containing further heterocyclic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4866—Organic macromolecular compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Chemical & Material Sciences (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
General Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Immunology (AREA)
Epidemiology (AREA)
Virology (AREA)
Communicable Diseases (AREA)
Bioinformatics & Cheminformatics (AREA)
Oncology (AREA)
Engineering & Computer Science (AREA)
Molecular Biology (AREA)
Tropical Medicine & Parasitology (AREA)
AIDS & HIV (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicinal Preparation (AREA)
Indole Compounds (AREA)
Pyridine Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Hydrogenated Pyridines (AREA)
Other In-Based Heterocyclic Compounds (AREA)
Pyrane Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Pyrrole Compounds (AREA)
Quinoline Compounds (AREA)
Furan Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Heterocyclic Compounds Containing Sulfur Atoms (AREA)
Thiazole And Isothizaole Compounds (AREA)

IS4627A 1995-06-06 1997-12-04 Lyfjablanda sem samanstendur af hindra fyrir proteinkljúfandi hvata og monoglycerid IS2661B (is)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US46849395A	1995-06-06	1995-06-06
US08/616,233 US6008228A (en)	1995-06-06	1996-05-07	Pharmaceutical compositions containing proteinase inhibitors
PCT/EP1996/002431 WO1996039142A1 (en)	1995-06-06	1996-06-04	Pharmaceutical composition comprising a proteinase inhibitor and a monoglyceride

Publications (2)

Publication Number	Publication Date
IS4627A true IS4627A (is)	1997-12-04
IS2661B IS2661B (is)	2010-08-15

Family

ID=27042422

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IS4627A IS2661B (is)	1995-06-06	1997-12-04	Lyfjablanda sem samanstendur af hindra fyrir proteinkljúfandi hvata og monoglycerid

Country Status (26)

Country	Link
EP (1)	EP0831826B1 (is)
JP (1)	JP3238412B2 (is)
CN (1)	CN1092960C (is)
AT (1)	ATE226075T1 (is)
AU (1)	AU709796B2 (is)
BG (1)	BG63711B1 (is)
BR (1)	BR9610842A (is)
CA (1)	CA2224125C (is)
CY (1)	CY2373B1 (is)
CZ (1)	CZ292192B6 (is)
DE (1)	DE69624354T2 (is)
DK (1)	DK0831826T3 (is)
EA (1)	EA001413B1 (is)
ES (1)	ES2182996T3 (is)
HU (1)	HU223899B1 (is)
IL (1)	IL122353A0 (is)
IS (1)	IS2661B (is)
MX (1)	MX9709193A (is)
NO (1)	NO324531B1 (is)
NZ (1)	NZ311646A (is)
OA (1)	OA10546A (is)
PL (1)	PL184820B1 (is)
PT (1)	PT831826E (is)
SK (1)	SK282121B6 (is)
TR (1)	TR199701541T1 (is)
WO (1)	WO1996039142A1 (is)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
PL192080B1 (pl) *	1997-07-29	2006-08-31	Upjohn Co	Kompozycja farmaceutyczna zawierająca związek piranonowy
HU228923B1 (en)	1997-07-29	2013-06-28	Upjohn Co	Pharmaceutical composition for acidic lipophilic compounds in a form of a self-emulsifying formulation
CA2361424C (en) *	1999-02-08	2009-04-28	Intarcia Therapeutics, Inc.	Stable non-aqueous single phase viscous vehicles and formulations utilizing such vehicles
US7258869B1 (en)	1999-02-08	2007-08-21	Alza Corporation	Stable non-aqueous single phase viscous vehicles and formulations utilizing such vehicle
US7919109B2 (en)	1999-02-08	2011-04-05	Intarcia Therapeutics, Inc.	Stable non-aqueous single phase viscous vehicles and formulations utilizing such vehicles
US6956048B2 (en)	1999-03-31	2005-10-18	Pharmacia & Upjohn Company	Pharmaceutical emulsions for retroviral protease inhibitors
US6309663B1 (en) *	1999-08-17	2001-10-30	Lipocine Inc.	Triglyceride-free compositions and methods for enhanced absorption of hydrophilic therapeutic agents
BR0202252A (pt)	2002-06-12	2004-06-29	Cristalia Prod Quimicos Farm	Composição farmacêutica solúvel estável para administração de inibidores da hiv protease e processo de obtenção de composições farmacêuticas concentradas para a administração de inibidores da hiv protease
US7731947B2 (en)	2003-11-17	2010-06-08	Intarcia Therapeutics, Inc.	Composition and dosage form comprising an interferon particle formulation and suspending vehicle
WO2006083761A2 (en)	2005-02-03	2006-08-10	Alza Corporation	Solvent/polymer solutions as suspension vehicles
US11246913B2 (en)	2005-02-03	2022-02-15	Intarcia Therapeutics, Inc.	Suspension formulation comprising an insulinotropic peptide
KR101106510B1 (ko)	2006-05-30	2012-01-20	인타르시아 세라퓨틱스 인코포레이티드	투피스, 내부채널 삼투압 전달 시스템 유동 조절기
WO2008133908A2 (en)	2007-04-23	2008-11-06	Intarcia Therapeutics, Inc.	Suspension formulations of insulinotropic peptides and uses thereof
CA2726861C (en)	2008-02-13	2014-05-27	Intarcia Therapeutics, Inc.	Devices, formulations, and methods for delivery of multiple beneficial agents
EP2108705A1 (en)	2008-04-08	2009-10-14	Universität Duisburg-Essen	Method for analysing the epigenetic status of the HtrA 1 gene in a biological sample
RU2547990C2 (ru)	2009-09-28	2015-04-10	Интарсия Терапьютикс, Инк.	Быстрое достижение и/или прекращение существенной стабильной доставки лекарственного средства
US20120208755A1 (en)	2011-02-16	2012-08-16	Intarcia Therapeutics, Inc.	Compositions, Devices and Methods of Use Thereof for the Treatment of Cancers
US9889085B1 (en)	2014-09-30	2018-02-13	Intarcia Therapeutics, Inc.	Therapeutic methods for the treatment of diabetes and related conditions for patients with high baseline HbA1c
RU2730996C2 (ru)	2015-06-03	2020-08-26	Интарсия Терапьютикс, Инк.	Системы установки и извлечения имплантата
KR102574993B1 (ko)	2016-05-16	2023-09-06	인타르시아 세라퓨틱스 인코포레이티드	글루카곤-수용체 선택적 폴리펩티드 및 이들의 이용 방법
USD860451S1 (en)	2016-06-02	2019-09-17	Intarcia Therapeutics, Inc.	Implant removal tool
USD840030S1 (en)	2016-06-02	2019-02-05	Intarcia Therapeutics, Inc.	Implant placement guide
JP7286542B2 (ja)	2017-01-03	2023-06-05	インターシアセラピューティクス，インコーポレイティド	Ｇｌｐ－１受容体アゴニストの持続的投与及び薬物の同時投与を含む方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB8927913D0 (en) *	1989-12-11	1990-02-14	Hoffmann La Roche	Amino acid derivatives
IL110752A (en) *	1993-09-13	2000-07-26	Abbott Lab	Liquid semi-solid or solid pharmaceutical composition for an HIV protease inhibitor

1996
- 1996-06-04 ES ES96921929T patent/ES2182996T3/es not_active Expired - Lifetime
- 1996-06-04 PL PL96323860A patent/PL184820B1/pl unknown
- 1996-06-04 HU HU9801905A patent/HU223899B1/hu active IP Right Grant
- 1996-06-04 DK DK96921929T patent/DK0831826T3/da active
- 1996-06-04 AT AT96921929T patent/ATE226075T1/de active
- 1996-06-04 DE DE69624354T patent/DE69624354T2/de not_active Expired - Lifetime
- 1996-06-04 EP EP96921929A patent/EP0831826B1/en not_active Expired - Lifetime
- 1996-06-04 CA CA002224125A patent/CA2224125C/en not_active Expired - Lifetime
- 1996-06-04 EA EA199800023A patent/EA001413B1/ru not_active IP Right Cessation
- 1996-06-04 CZ CZ19973803A patent/CZ292192B6/cs not_active IP Right Cessation
- 1996-06-04 BR BR9610842A patent/BR9610842A/pt not_active IP Right Cessation
- 1996-06-04 SK SK1627-97A patent/SK282121B6/sk not_active IP Right Cessation
- 1996-06-04 NZ NZ311646A patent/NZ311646A/en not_active IP Right Cessation
- 1996-06-04 IL IL12235396A patent/IL122353A0/xx not_active IP Right Cessation
- 1996-06-04 PT PT96921929T patent/PT831826E/pt unknown
- 1996-06-04 AU AU63004/96A patent/AU709796B2/en not_active Expired
- 1996-06-04 JP JP50014397A patent/JP3238412B2/ja not_active Expired - Lifetime
- 1996-06-04 CN CN96194327A patent/CN1092960C/zh not_active Expired - Lifetime
- 1996-06-04 WO PCT/EP1996/002431 patent/WO1996039142A1/en not_active Ceased
- 1996-06-04 MX MX9709193A patent/MX9709193A/es unknown
- 1996-06-04 TR TR97/01541T patent/TR199701541T1/xx unknown
1997
- 1997-12-04 IS IS4627A patent/IS2661B/is unknown
- 1997-12-05 OA OA70151A patent/OA10546A/en unknown
- 1997-12-05 BG BG102106A patent/BG63711B1/bg unknown
- 1997-12-05 NO NO19975665A patent/NO324531B1/no not_active IP Right Cessation
2003
- 2003-08-22 CY CY0300057A patent/CY2373B1/xx unknown

Also Published As

Publication number	Publication date
JP3238412B2 (ja)	2001-12-17
WO1996039142A1 (en)	1996-12-12
BG63711B1 (bg)	2002-10-31
DK0831826T3 (da)	2003-02-03
NO975665D0 (no)	1997-12-05
JPH10507202A (ja)	1998-07-14
CA2224125C (en)	2004-09-28
BR9610842A (pt)	1999-07-13
CY2373B1 (en)	2004-06-04
ES2182996T3 (es)	2003-03-16
EA199800023A1 (ru)	1998-08-27
OA10546A (en)	2002-05-29
DE69624354D1 (de)	2002-11-21
TR199701541T1 (xx)	1998-03-21
PT831826E (pt)	2003-02-28
MX9709193A (es)	1998-03-31
IL122353A0 (en)	1998-04-05
EP0831826A1 (en)	1998-04-01
ATE226075T1 (de)	2002-11-15
EA001413B1 (ru)	2001-02-26
CN1092960C (zh)	2002-10-23
SK282121B6 (sk)	2001-11-06
HK1010136A1 (en)	1999-06-17
AU709796B2 (en)	1999-09-09
PL323860A1 (en)	1998-04-27
PL184820B1 (pl)	2002-12-31
HUP9801905A3 (en)	2001-04-28
HUP9801905A2 (hu)	1999-05-28
HU223899B1 (hu)	2005-03-29
IS2661B (is)	2010-08-15
BG102106A (en)	1998-08-31
NO324531B1 (no)	2007-11-12
CN1186434A (zh)	1998-07-01
CA2224125A1 (en)	1996-12-12
CZ380397A3 (cs)	1998-03-18
DE69624354T2 (de)	2003-06-05
EP0831826B1 (en)	2002-10-16
NO975665L (no)	1998-02-05
CZ292192B6 (cs)	2003-08-13
AU6300496A (en)	1996-12-24
NZ311646A (en)	2000-02-28
SK162797A3 (en)	1998-05-06

Publication	Publication Date	Title
IS4627A (is)	1997-12-04	Lyfjablanda sem samanstendur af hindra fyrir proteinkljúfandi hvata og monoglycerid
AU2012199A (en)	1999-07-19	Prodrugs of aspartyl protease inhibitors
ZA9811830B (en)	2000-06-23	Prodrugs of aspartyl protease inhibitors.
FI973360A7 (fi)	1997-08-15	Uusia dipeptidisiä amidiineja trombiininestäjiksi
TR200200129T2 (tr)	2002-06-21	Hepatit C inhibitörü tri-peptidler
AU7371998A (en)	1998-11-27	Inhibitors of protein isoprenyl transferases
LV11951A (lv)	1998-01-20	Mikrosomalo trigliceridu transportproteinu inhibitors
NO2013019I2 (no)	2013-12-17	Aliskiren eller et farmasøytisk akseptabelt salt derav, og hydroklortiazid eller et farmasøytisk akseptabelt salt derav.
NO20006716D0 (no)	2000-12-29	Proteaseinhibitorer
NO982809L (no)	1998-08-20	Prolegemidler av tombin-inhibitorer
ATE218336T1 (de)	2002-06-15	Verwendung von 3-benzoylphenylessigsäuren, deren estern oder amiden zur behandlung von glc1a glaukom
AU7117496A (en)	1997-04-28	Peptide inhibitor for viral protease derived from the transframe region of the gag-pol gene
MY116525A (en)	2004-02-28	Pharmaceutical composition comprising a proteinase inhibitor and a monoglyceride
IT1307928B1 (it)	2001-11-29	Metodo di sintesi di nitrossimetilfenil esteri di derivatidell'aspirina.
DK0842185T3 (da)	2002-02-04	Ara-C-derivater
AU1287100A (en)	2000-06-13	Peptide inhibitor of browman-birk type
AU6678398A (en)	1998-09-18	Inhibitors of isoprenyl transferase
EP1030661A4 (en)	2002-07-17	N, N-DIETHYLGLYCOLAMIDOESTER OF INDOLS AS PRELIMINARY MEDICINE OF SPLA 2 INHIBITORS
HK1032225A (en)	2001-07-13	Prodrugs of aspartyl protease inhibitors
ECSP961778A (es)	1997-11-04	Composiciones que incrementan la biodisponibilidad de inhibidores de proteinasa
TNSN96081A1 (fr)	2005-03-15	Composition antiretrovirale
ZA969078B (en)	1998-04-29	Inhibitors of cysteine protease.