IS5257A - Substitutive pyrazole which inhibits p38 kinase - Google Patents
Substitutive pyrazole which inhibits p38 kinaseInfo
- Publication number
- IS5257A IS5257A IS5257A IS5257A IS5257A IS 5257 A IS5257 A IS 5257A IS 5257 A IS5257 A IS 5257A IS 5257 A IS5257 A IS 5257A IS 5257 A IS5257 A IS 5257A
- Authority
- IS
- Iceland
- Prior art keywords
- substitutive
- pyrazole
- kinase
- inhibits
- substitutive pyrazole
- Prior art date
Links
- WTKZEGDFNFYCGP-UHFFFAOYSA-N Pyrazole Chemical compound C=1C=NNC=1 WTKZEGDFNFYCGP-UHFFFAOYSA-N 0.000 title 1
- 102000002574 p38 Mitogen-Activated Protein Kinases Human genes 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
- A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
- C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Rheumatology (AREA)
- Immunology (AREA)
- Physical Education & Sports Medicine (AREA)
- Pulmonology (AREA)
- Hematology (AREA)
- Pain & Pain Management (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Cardiology (AREA)
- Urology & Nephrology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Endocrinology (AREA)
- Vascular Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Transplantation (AREA)
- Dermatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US4757097P | 1997-05-22 | 1997-05-22 | |
| PCT/US1998/010436 WO1998052940A1 (en) | 1997-05-22 | 1998-05-22 | SUBSTITUTED PYRAZOLES AS p38 KINASE INHIBITORS |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IS5257A true IS5257A (en) | 1999-11-19 |
Family
ID=21949743
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IS5257A IS5257A (en) | 1997-05-22 | 1999-11-19 | Substitutive pyrazole which inhibits p38 kinase |
Country Status (24)
| Country | Link |
|---|---|
| EP (1) | EP1000055A1 (en) |
| JP (1) | JP2002508754A (en) |
| KR (1) | KR20010012854A (en) |
| CN (1) | CN1264377A (en) |
| AP (1) | AP1246A (en) |
| AU (1) | AU754830C (en) |
| BG (1) | BG64313B1 (en) |
| BR (1) | BR9809147A (en) |
| CA (1) | CA2291115A1 (en) |
| EA (1) | EA003925B1 (en) |
| EE (1) | EE9900527A (en) |
| GE (1) | GEP20033053B (en) |
| HU (1) | HUP0001880A3 (en) |
| ID (1) | ID22982A (en) |
| IL (1) | IL132991A (en) |
| IS (1) | IS5257A (en) |
| NO (1) | NO995695L (en) |
| NZ (1) | NZ501112A (en) |
| OA (1) | OA12981A (en) |
| PL (1) | PL337020A1 (en) |
| SK (1) | SK157899A3 (en) |
| TR (1) | TR200000235T2 (en) |
| WO (1) | WO1998052940A1 (en) |
| ZA (1) | ZA984358B (en) |
Families Citing this family (88)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW289752B (en) * | 1994-03-11 | 1996-11-01 | Ciba Geigy Ag | |
| US5559137A (en) * | 1994-05-16 | 1996-09-24 | Smithkline Beecham Corp. | Compounds |
| US6979686B1 (en) | 2001-12-07 | 2005-12-27 | Pharmacia Corporation | Substituted pyrazoles as p38 kinase inhibitors |
| US6514977B1 (en) * | 1997-05-22 | 2003-02-04 | G.D. Searle & Company | Substituted pyrazoles as p38 kinase inhibitors |
| EP1019394A1 (en) | 1997-05-22 | 2000-07-19 | G.D. Searle & Co. | PYRAZOLE DERIVATIVES AS p38 KINASE INHIBITORS |
| AU7966198A (en) | 1997-06-13 | 1998-12-30 | Smithkline Beecham Corporation | Novel pyrazole and pyrazoline substituted compounds |
| US7301021B2 (en) | 1997-07-02 | 2007-11-27 | Smithkline Beecham Corporation | Substituted imidazole compounds |
| US6858617B2 (en) | 1998-05-26 | 2005-02-22 | Smithkline Beecham Corporation | Substituted imidazole compounds |
| US6184226B1 (en) * | 1998-08-28 | 2001-02-06 | Scios Inc. | Quinazoline derivatives as inhibitors of P-38 α |
| US6649617B1 (en) | 1998-10-07 | 2003-11-18 | Smithkline Beecham Corporation | Treatment for stroke management |
| DE69914357T2 (en) | 1998-11-04 | 2004-11-11 | Smithkline Beecham Corp. | PYRIDIN-4-YL OR PYRIMIDIN-4-YL SUBSTITUTED PYRAZINE |
| CA2355075C (en) | 1998-12-16 | 2009-12-08 | Aventis Pharma Limited | Heteroaryl-cyclic acetals |
| US6191147B1 (en) * | 1998-12-24 | 2001-02-20 | Ppd Discovery, Inc. | Pyrazole compounds and uses thereof |
| KR100711538B1 (en) * | 1998-12-25 | 2007-04-27 | 아스카 세이야쿠 가부시키가이샤 | Aminopyrazole derivatives |
| TW502019B (en) | 1999-03-26 | 2002-09-11 | Cocensys Inc | Aryl substituted pyrazoles, imidazoles, oxazoles, thiazoles and pyrroles, and the use thereof |
| DE60020560T2 (en) | 1999-06-03 | 2006-04-27 | Teikoku Hormone Mfg. Co., Ltd. | SUBSTITUTED PYRAZOLE DERIVATIVES |
| US7122666B2 (en) | 1999-07-21 | 2006-10-17 | Sankyo Company, Limited | Heteroaryl-substituted pyrrole derivatives, their preparation and their therapeutic uses |
| BR0013551A (en) * | 1999-08-13 | 2003-06-17 | Vertex Pharma | Inhibitors of cjun (jnk) n-terminal kinases and other protein kinases |
| AU7922100A (en) * | 1999-10-25 | 2001-05-08 | Basf Aktiengesellschaft | Agrochemical compositions containing pyrazoles as the active agents and use of said compositions as plant protection agents with a fungicidal action |
| DE19952147A1 (en) | 1999-10-29 | 2001-05-03 | Boehringer Ingelheim Pharma | New cyclopropanes, pharmaceutical compositions containing these compounds and process for their preparation |
| EP1233950B1 (en) | 1999-11-23 | 2005-10-05 | Smithkline Beecham Corporation | 3,4-DIHYDRO-(1H)QUINAZOLIN-2-ONE COMPOUNDS AS CSBP/P39 kINASE INHIBITORS |
| ATE281439T1 (en) | 1999-11-23 | 2004-11-15 | Smithkline Beecham Corp | 3,4-DIHYDRO-(1H)CHINAZOLINE-2-ONE COMPOUNDS AS CSBP/P38 KINASE INHIBITORS |
| JP2003514900A (en) | 1999-11-23 | 2003-04-22 | スミスクライン・ビーチャム・コーポレイション | 3,4-Dihydro- (1H) -quinazolin-2-one compounds as CSBP / p38 kinase inhibitors |
| US7235551B2 (en) | 2000-03-02 | 2007-06-26 | Smithkline Beecham Corporation | 1,5-disubstituted-3,4-dihydro-1h-pyrimido[4,5-d]pyrimidin-2-one compounds and their use in treating csbp/p38 kinase mediated diseases |
| HK1052705B (en) | 2000-08-14 | 2006-09-29 | Ortho-Mcneil Pharmaceutical, Inc. | Substituted pyrazoles |
| US7199124B2 (en) | 2001-02-02 | 2007-04-03 | Takeda Pharmaceutical Company Limited | JNK inhibitor |
| GB0102687D0 (en) | 2001-02-02 | 2001-03-21 | Pharmacia & Upjohn Spa | Oxazolyl-pyrazole derivatives active as kinase inhibitors,process for their preparation and pharmaceutical compositions comprising them |
| US7074801B1 (en) | 2001-04-26 | 2006-07-11 | Eisai Co., Ltd. | Nitrogen-containing condensed cyclic compound having a pyrazolyl group as a substituent group and pharmaceutical composition thereof |
| SK287857B6 (en) | 2001-05-24 | 2012-01-04 | Eli Lilly And Company | Novel pyrrole derivatives as pharmaceutical agents |
| AU2002330096B2 (en) | 2001-09-25 | 2007-11-08 | Pharmacia Corporation | Process for making substituted pyrazoles |
| RU2277534C2 (en) * | 2001-09-25 | 2006-06-10 | Фармация Корпорейшн | Method for preparing substituted pyrazoles |
| US7057049B2 (en) | 2001-09-25 | 2006-06-06 | Pharmacia Corporation | Process for making substituted pyrazoles |
| TW200400960A (en) * | 2002-06-05 | 2004-01-16 | Pharmacia Corp | Novel pyrazoles and their use as P38 kinase inhibitors |
| ES2278170T3 (en) | 2002-07-09 | 2007-08-01 | BOEHRINGER INGELHEIM PHARMA GMBH & CO.KG | PHARMACEUTICAL COMPOSITIONS OF ANTICOLINERGIC AND INHIBITORS OF QUINASE P38 IN THE TREATMENT OF RESPIRATORY DISEASES. |
| GB0215844D0 (en) | 2002-07-09 | 2002-08-14 | Novartis Ag | Organic compounds |
| GB0217786D0 (en) * | 2002-07-31 | 2002-09-11 | Glaxo Group Ltd | Compounds |
| AU2003265395A1 (en) | 2002-08-14 | 2004-03-03 | Ppd Discovery, Inc. | Prenylation inhibitors and methods of their synthesis and use |
| US6649638B1 (en) | 2002-08-14 | 2003-11-18 | Ppd Discovery, Inc. | Prenylation inhibitors and methods of their synthesis and use |
| WO2004026302A1 (en) * | 2002-09-19 | 2004-04-01 | Eli Lilly And Company | Methods of inhibiting tgf beta with substituted pyrazoles |
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| US7622471B2 (en) | 2003-02-07 | 2009-11-24 | Daiichi Pharmaceutical Co., Ltd. | Pyrazole derivatives having a pyridazine and pyridine functionality |
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| CA2819961C (en) * | 2010-12-20 | 2015-08-18 | Pfizer Inc. | Novel fused pyridine compounds as casein kinase inhibitors |
| AR086992A1 (en) | 2011-06-20 | 2014-02-05 | Bayer Ip Gmbh | TIENILPIRI (MI) DINILPIRAZOLES |
| WO2013025664A1 (en) | 2011-08-17 | 2013-02-21 | Boehringer Ingelheim International Gmbh | Indenopyridine derivatives |
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| JP6211522B2 (en) | 2011-10-06 | 2017-10-11 | バイエル・インテレクチュアル・プロパティ・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツングＢａｙｅｒ Ｉｎｔｅｌｌｅｃｔｕａｌ Ｐｒｏｐｅｒｔｙ ＧｍｂＨ | Heterocyclylpyri (mi) dinylpyrazole |
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Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2753659B2 (en) * | 1990-09-03 | 1998-05-20 | 株式会社大塚製薬工場 | Pyrazole derivatives |
| US5593992A (en) * | 1993-07-16 | 1997-01-14 | Smithkline Beecham Corporation | Compounds |
| US5559137A (en) * | 1994-05-16 | 1996-09-24 | Smithkline Beecham Corp. | Compounds |
| US5486534A (en) * | 1994-07-21 | 1996-01-23 | G. D. Searle & Co. | 3,4-substituted pyrazoles for the treatment of inflammation |
| JP3734180B2 (en) * | 1994-12-28 | 2006-01-11 | エーザイ株式会社 | New pyrazole derivatives |
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1998
- 1998-05-22 AU AU75883/98A patent/AU754830C/en not_active Ceased
- 1998-05-22 KR KR19997010820A patent/KR20010012854A/en not_active Ceased
- 1998-05-22 CA CA002291115A patent/CA2291115A1/en not_active Abandoned
- 1998-05-22 EE EEP199900527A patent/EE9900527A/en unknown
- 1998-05-22 EP EP98923642A patent/EP1000055A1/en not_active Withdrawn
- 1998-05-22 GE GEAP19985095A patent/GEP20033053B/en unknown
- 1998-05-22 SK SK1578-99A patent/SK157899A3/en unknown
- 1998-05-22 IL IL13299198A patent/IL132991A/en not_active IP Right Cessation
- 1998-05-22 JP JP55065098A patent/JP2002508754A/en not_active Withdrawn
- 1998-05-22 BR BR9809147-6A patent/BR9809147A/en not_active Application Discontinuation
- 1998-05-22 EA EA199900953A patent/EA003925B1/en not_active IP Right Cessation
- 1998-05-22 NZ NZ501112A patent/NZ501112A/en unknown
- 1998-05-22 ID IDW991425A patent/ID22982A/en unknown
- 1998-05-22 AP APAP/P/1999/001715A patent/AP1246A/en active
- 1998-05-22 TR TR2000/00235T patent/TR200000235T2/en unknown
- 1998-05-22 ZA ZA984358A patent/ZA984358B/en unknown
- 1998-05-22 HU HU0001880A patent/HUP0001880A3/en unknown
- 1998-05-22 WO PCT/US1998/010436 patent/WO1998052940A1/en not_active Ceased
- 1998-05-22 CN CN98807369A patent/CN1264377A/en active Pending
- 1998-05-22 PL PL98337020A patent/PL337020A1/en unknown
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- 1999-11-22 OA OA9900252A patent/OA12981A/en unknown
- 1999-12-08 BG BG103964A patent/BG64313B1/en unknown
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| AP1246A (en) | 2004-02-07 |
| BG64313B1 (en) | 2004-09-30 |
| JP2002508754A (en) | 2002-03-19 |
| SK157899A3 (en) | 2000-08-14 |
| NO995695D0 (en) | 1999-11-19 |
| CN1264377A (en) | 2000-08-23 |
| NO995695L (en) | 2000-01-21 |
| IL132991A0 (en) | 2001-03-19 |
| ID22982A (en) | 1999-12-23 |
| EA199900953A1 (en) | 2000-10-30 |
| CA2291115A1 (en) | 1998-11-26 |
| AU754830B2 (en) | 2002-11-28 |
| KR20010012854A (en) | 2001-02-26 |
| ZA984358B (en) | 1999-05-24 |
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| EA003925B1 (en) | 2003-10-30 |
| EE9900527A (en) | 2000-06-15 |
| HUP0001880A2 (en) | 2001-03-28 |
| AP9901715A0 (en) | 1999-12-31 |
| BG103964A (en) | 2000-08-31 |
| NZ501112A (en) | 2002-10-25 |
| GEP20033053B (en) | 2003-08-25 |
| IL132991A (en) | 2005-11-20 |
| OA12981A (en) | 2006-10-13 |
| PL337020A1 (en) | 2000-07-31 |
| WO1998052940A1 (en) | 1998-11-26 |
| AU7588398A (en) | 1998-12-11 |
| HUP0001880A3 (en) | 2002-03-28 |
| TR200000235T2 (en) | 2000-05-22 |
| AU754830C (en) | 2004-02-12 |
| BR9809147A (en) | 2000-08-01 |
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