IS5449A - Umbreytt K-vítamín-háð fjölpeptíð - Google Patents

Umbreytt K-vítamín-háð fjölpeptíð

Info

Publication number: IS5449A
Authority: IS; Iceland
Prior art keywords: vitamin; transformed; dependent polypeptide; polypeptide; dependent
Prior art date: 1997-10-23

Application number

IS5449A

Other languages

English (en)

Inventor

Gary L Nelsestuen

Original Assignee

Univ Minnesota

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-10-23

Filing date

2000-04-14

Publication date

2000-04-14

2000-04-14 Application filed by Univ Minnesota filed Critical Univ Minnesota

2000-04-14 Publication of IS5449A publication Critical patent/IS5449A/is

Links

229930003448 Vitamin K Natural products 0.000 title 1
230000001419 dependent effect Effects 0.000 title 1
SHUZOJHMOBOZST-UHFFFAOYSA-N phylloquinone Natural products CC(C)CCCCC(C)CCC(C)CCCC(=CCC1=C(C)C(=O)c2ccccc2C1=O)C SHUZOJHMOBOZST-UHFFFAOYSA-N 0.000 title 1
229920001184 polypeptide Polymers 0.000 title 1
102000004196 processed proteins & peptides Human genes 0.000 title 1
108090000765 processed proteins & peptides Proteins 0.000 title 1
235000019168 vitamin K Nutrition 0.000 title 1
239000011712 vitamin K Substances 0.000 title 1
150000003721 vitamin K derivatives Chemical class 0.000 title 1
229940046010 vitamin k Drugs 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6424—Serine endopeptidases (3.4.21)
- C12N9/6437—Coagulation factor VIIa (3.4.21.21)
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6424—Serine endopeptidases (3.4.21)
- C12N9/644—Coagulation factor IXa (3.4.21.22)
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6424—Serine endopeptidases (3.4.21)
- C12N9/6464—Protein C (3.4.21.69)
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6424—Serine endopeptidases (3.4.21)
- C12N9/647—Blood coagulation factors not provided for in a preceding group or according to more than one of the proceeding groups
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/21—Serine endopeptidases (3.4.21)
- C12Y304/21021—Coagulation factor VIIa (3.4.21.21)
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/21—Serine endopeptidases (3.4.21)
- C12Y304/21022—Coagulation factor IXa (3.4.21.22)
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/21—Serine endopeptidases (3.4.21)
- C12Y304/21069—Protein C activated (3.4.21.69)
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Genetics & Genomics (AREA)
Bioinformatics & Cheminformatics (AREA)
Zoology (AREA)
Wood Science & Technology (AREA)
Biomedical Technology (AREA)
General Health & Medical Sciences (AREA)
General Engineering & Computer Science (AREA)
Biochemistry (AREA)
Medicinal Chemistry (AREA)
Molecular Biology (AREA)
Biotechnology (AREA)
Microbiology (AREA)
Hematology (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Public Health (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
Diabetes (AREA)
Physics & Mathematics (AREA)
Biophysics (AREA)
Plant Pathology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Enzymes And Modification Thereof (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)

IS5449A 1997-10-23 2000-04-14 Umbreytt K-vítamín-háð fjölpeptíð IS5449A (is)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US08/955,636 US6017882A (en)	1997-10-23	1997-10-23	Modified vitamin K-dependent polypeptides

Publications (1)

Publication Number	Publication Date
IS5449A true IS5449A (is)	2000-04-14

Family

ID=25497114

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IS5449A IS5449A (is)	1997-10-23	2000-04-14	Umbreytt K-vítamín-háð fjölpeptíð

Country Status (30)

Country	Link
US (1)	US6017882A (is)
EP (2)	EP1090128B1 (is)
JP (1)	JP4276379B2 (is)
KR (1)	KR20010031370A (is)
CN (1)	CN1246462C (is)
AP (1)	AP2000001811A0 (is)
AR (2)	AR020048A1 (is)
AT (1)	ATE390486T1 (is)
AU (1)	AU749279C (is)
BR (1)	BR9814611A (is)
CA (1)	CA2307175C (is)
DE (1)	DE69839313T2 (is)
DK (1)	DK1090128T3 (is)
EA (1)	EA200000449A1 (is)
ES (2)	ES2303362T3 (is)
HR (1)	HRP20000234A2 (is)
HU (1)	HU225993B1 (is)
ID (1)	ID26330A (is)
IL (1)	IL135603A0 (is)
IS (1)	IS5449A (is)
MY (1)	MY136336A (is)
NO (1)	NO20002025L (is)
NZ (1)	NZ504114A (is)
PL (1)	PL194194B1 (is)
PT (1)	PT1090128E (is)
SG (1)	SG105547A1 (is)
TR (1)	TR200001105T2 (is)
TW (1)	TW587081B (is)
WO (1)	WO1999020767A1 (is)
ZA (1)	ZA989597B (is)

Families Citing this family (50)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6747003B1 (en)	1997-10-23	2004-06-08	Regents Of The University Of Minnesota	Modified vitamin K-dependent polypeptides
US7247708B2 (en)	1997-10-23	2007-07-24	Regents Of The University Of Minnesota	Modified vitamin K-dependent polypeptides
US6693075B1 (en) *	1997-10-23	2004-02-17	Regents Of The University Of Minnesota	Modified vitamin K-dependent polypeptides
US6998122B1 (en)	1999-04-30	2006-02-14	Eli Lilly And Company	Protein C derivatives
EP1237917A2 (en) *	1999-11-19	2002-09-11	Eli Lilly And Company	Protein c derivatives
AU2001232736A1 (en)	2000-02-02	2001-08-14	Eli Lilly And Company	Protein c derivatives
PL204285B1 (pl)	2000-02-11	2009-12-31	Bayer Healthcare Llc	Koniugat polipeptydowy, polipeptyd, sekwencja nukleotydowa, wektor ekspresyjny, komórka gospodarz, sposób wytwarzania koniugatu polipeptydowego, środek farmaceutyczny i zastosowanie koniugatu polipeptydowego
WO2001059084A1 (en)	2000-02-11	2001-08-16	Eli Lilly And Company	Protein c derivatives
US7220837B1 (en)	2000-04-28	2007-05-22	Regents Of The University Of Minnesota	Modified vitamin K-dependent polypeptides
US7812132B2 (en)	2000-04-28	2010-10-12	Regents Of The University Of Minnesota	Modified vitamin K-dependent polypeptides
US6423826B1 (en)	2000-06-30	2002-07-23	Regents Of The University Of Minnesota	High molecular weight derivatives of vitamin K-dependent polypeptides
US7160540B2 (en) *	2000-06-30	2007-01-09	Regents Of The University Of Minnesota	Methods for detecting activity of clottings factors
US20030211094A1 (en)	2001-06-26	2003-11-13	Nelsestuen Gary L.	High molecular weight derivatives of vitamin k-dependent polypeptides
US6828306B2 (en) *	2000-07-31	2004-12-07	Ottawa Heart Institute Research Corporation	Charged lipid compositions and methods for their use
US6933367B2 (en)	2000-10-18	2005-08-23	Maxygen Aps	Protein C or activated protein C-like molecules
EP1370649A1 (en) *	2001-03-02	2003-12-17	T.A.C. Thrombosis and Coagulation AB	Protein c variants
WO2003073980A2 (en) *	2002-03-01	2003-09-12	T.A.C. Thrombosis And Coagulation Aktiebolag	Recombinant protein c variants
US20030186862A1 (en) *	2002-04-02	2003-10-02	Nelsestuen Gary L.	Factor VIIa compositions
BR0309576A (pt)	2002-04-30	2005-02-09	Maxygen Holdings Ltd	Variante de polipeptìdeo do fator vii (fvii) ou fator viia (fviia), sequência de nucleotìdeo, vetor de expressão, célula hospedeira, composição farmacêutica, uso de uma variante, e, método para tratar um mamìfero que tenha uma doença ou um distúrbio em que a formação de coágulo é desejável
US20030232075A1 (en) *	2002-05-06	2003-12-18	University Of Minnesota, A Minnesota Corporation	Compositions for producing factor Xa
CA2490342C (en)	2002-06-21	2015-06-16	Novo Nordisk A/S	Stabilised solid compositions of factor vii polypeptides
US20040176704A1 (en) *	2003-03-04	2004-09-09	Stevens Timothy A	Collection device adapted to accept cartridge for point of care system
JP4885707B2 (ja)	2003-03-18	2012-02-29	ノボノルディスクヘルスケアアクチェンゲゼルシャフト	セリンプロテアーゼを含むｇｌａ−残基の生産方法
AU2004221761B2 (en)	2003-03-20	2010-01-07	Bayer Healthcare Llc	FVII or FVIIa variants
DE602004025576D1 (de) *	2003-06-19	2010-04-01	Bayer Healthcare Llc	Varianten der faktor-vii- oder -viia-gla-domäne
ATE547519T1 (de)	2003-09-09	2012-03-15	Novo Nordisk Healthcare Ag	Gerinnungsfaktor-vii-polypeptide
KR100755967B1 (ko) *	2003-10-23	2007-09-06	한국타이어 주식회사	타이어의 비드와 휠의 갭 측정장치
EP1711513B1 (en)	2003-12-01	2014-07-02	Novo Nordisk Health Care AG	Nanofiltration of factor vii solutions to remove virus
ES2676644T3 (es)	2003-12-19	2018-07-23	Novo Nordisk Health Care Ag	Composiciones estabilizadas de polipéptidos de factor VII
EP2368579A1 (en)	2004-01-21	2011-09-28	Novo Nordisk Health Care AG	Transglutaminase mediated conjugation of peptides
CN101098883B (zh)	2004-12-23	2013-01-23	诺和诺德医疗保健公司	减少含有目的维生素k依赖性蛋白质的组合物中的蛋白质污染物的含量
US8206750B2 (en)	2005-03-24	2012-06-26	Cerenis Therapeutics Holding S.A.	Charged lipoprotein complexes and their uses
US20080188400A1 (en) *	2005-04-26	2008-08-07	Maxygen Holdings Ltd.	Methods For Treating Bleeding
JP5335422B2 (ja)	2005-06-17	2013-11-06	ノボノルディスクヘルスケアアクチェンゲゼルシャフト	少なくとも１つの非天然のシステインを含んでいる操作されたタンパク質の選択的な還元および誘導体化
JP5147692B2 (ja)	2005-07-13	2013-02-20	ノボノルディスクヘルスケアアーゲー	治療用タンパク質生成のための宿主細胞タンパク質ノックアウト細胞
EP1924689B1 (en)	2005-09-01	2014-08-13	Novo Nordisk Health Care AG	Hydrophobic interaction chromatography purification of factor vii polypeptides
JP5690047B2 (ja)	2005-09-14	2015-03-25	ノボノルディスクヘルスケアアーゲー	ヒト凝固第ｖｉｉ因子ポリペプチド
EP2059527B1 (en)	2006-09-01	2014-12-03	Novo Nordisk Health Care AG	Modified glycoproteins
WO2008078189A2 (en) *	2006-12-20	2008-07-03	Bayer Healthcare Llc	Factor vii and viia compositions
WO2008127702A2 (en)	2007-04-13	2008-10-23	Catalyst Biosciences, Inc.	Modified factor vii polypetides and uses thereof
US20080305157A1 (en) *	2007-06-08	2008-12-11	University Of Maryland Office Of Technology Commercialization	Encapsulation and separation of charged organic solutes inside catanionic vesicles
AU2008345231B2 (en)	2007-12-27	2014-09-11	Takeda Pharmaceutical Company Limited	Cell culture processes
TWI465247B (zh)	2008-04-11	2014-12-21	Catalyst Biosciences Inc	經修飾的因子ｖｉｉ多肽和其用途
ES2966234T3 (es)	2009-06-09	2024-04-18	Prolong Pharmaceuticals Llc	Composiciones de hemoglobina
WO2011074578A1 (ja) *	2009-12-14	2011-06-23	国立大学法人北海道大学	脂質膜構造体に細胞透過能を付与および／または脂質膜構造体の細胞透過能を増強するペプチド、ならびにそれらペプチドと結合した脂質を構成脂質として含む、細胞透過能を有するまたは細胞透過能が増強された脂質膜構造体
TWI595004B (zh)	2010-11-03	2017-08-11	介控生化科技公司	經修飾之第九因子多胜肽及其用途
US9145552B2 (en)	2012-07-25	2015-09-29	Catalyst Biosciences, Inc.	Modified factor X polypeptides and uses thereof
US11491212B1 (en)	2017-09-27	2022-11-08	Catalyst Biosciences, Inc.	Subcutaneous administration of modified factor IX polypeptides and treatment of hemophilia B
US20210069306A1 (en)	2019-08-15	2021-03-11	Catalyst Biosciences, Inc.	Modified factor vii polypeptides for subcutaneous administration and on-demand treatment
WO2021154414A2 (en)	2020-01-29	2021-08-05	Catalyst Biosciences, Inc.	Gene therapy for hemophilia b with a chimeric aav capsid vector encoding modified factor ix polypeptides

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
PT87688B (pt) *	1987-06-12	1992-09-30	Hoechst Japan	Processo para a preparacao de proteina hibrida c
JPH0246296A (ja) *	1988-08-09	1990-02-15	Hoechst Japan Ltd	雑種プロテインｃ及びその製造方法
US5580560A (en) *	1989-11-13	1996-12-03	Novo Nordisk A/S	Modified factor VII/VIIa
CA2074839C (en) *	1990-01-29	2000-11-14	Kathleen L. Berkner	Modified factor vii anticoagulant proteins
US5504064A (en) *	1991-04-10	1996-04-02	Oklahoma Medical Research Foundation	Treatment of bleeding with modified tissue factor in combination with an activator of FVII

1997
- 1997-10-23 US US08/955,636 patent/US6017882A/en not_active Expired - Lifetime
1998
- 1998-10-20 TW TW087117304A patent/TW587081B/zh active
- 1998-10-20 ID IDW20000983A patent/ID26330A/id unknown
- 1998-10-20 DE DE69839313T patent/DE69839313T2/de not_active Expired - Lifetime
- 1998-10-20 KR KR1020007004378A patent/KR20010031370A/ko not_active Ceased
- 1998-10-20 AU AU27024/99A patent/AU749279C/en not_active Ceased
- 1998-10-20 JP JP2000517087A patent/JP4276379B2/ja not_active Expired - Fee Related
- 1998-10-20 AP APAP/P/2000/001811A patent/AP2000001811A0/en unknown
- 1998-10-20 TR TR2000/01105T patent/TR200001105T2/xx unknown
- 1998-10-20 HU HU0102257A patent/HU225993B1/hu not_active IP Right Cessation
- 1998-10-20 ES ES98967009T patent/ES2303362T3/es not_active Expired - Lifetime
- 1998-10-20 HR HR20000234A patent/HRP20000234A2/hr not_active Application Discontinuation
- 1998-10-20 NZ NZ504114A patent/NZ504114A/xx unknown
- 1998-10-20 CN CNB988125811A patent/CN1246462C/zh not_active Expired - Fee Related
- 1998-10-20 AT AT98967009T patent/ATE390486T1/de active
- 1998-10-20 EP EP98967009A patent/EP1090128B1/en not_active Expired - Lifetime
- 1998-10-20 EA EA200000449A patent/EA200000449A1/ru unknown
- 1998-10-20 SG SG200203078A patent/SG105547A1/en unknown
- 1998-10-20 ES ES05026205.4T patent/ES2496104T3/es not_active Expired - Lifetime
- 1998-10-20 EP EP05026205.4A patent/EP1676919B1/en not_active Expired - Lifetime
- 1998-10-20 BR BR9814611-4A patent/BR9814611A/pt active Search and Examination
- 1998-10-20 CA CA002307175A patent/CA2307175C/en not_active Expired - Fee Related
- 1998-10-20 IL IL13560398A patent/IL135603A0/xx unknown
- 1998-10-20 DK DK98967009T patent/DK1090128T3/da active
- 1998-10-20 PL PL98340284A patent/PL194194B1/pl unknown
- 1998-10-20 PT PT98967009T patent/PT1090128E/pt unknown
- 1998-10-20 WO PCT/US1998/022152 patent/WO1999020767A1/en not_active Ceased
- 1998-10-21 ZA ZA989597A patent/ZA989597B/xx unknown
- 1998-10-22 AR ARP980105278A patent/AR020048A1/es unknown
- 1998-10-22 MY MYPI98004808A patent/MY136336A/en unknown
2000
- 2000-04-14 IS IS5449A patent/IS5449A/is unknown
- 2000-04-18 NO NO20002025A patent/NO20002025L/no not_active Application Discontinuation
2002
- 2002-03-20 AR ARP020101003A patent/AR035786A2/es active IP Right Grant

Also Published As

Publication number	Publication date
HUP0102257A2 (hu)	2001-09-28
JP4276379B2 (ja)	2009-06-10
JP2001520042A (ja)	2001-10-30
ZA989597B (en)	1999-04-23
TW587081B (en)	2004-05-11
AU2702499A (en)	1999-05-10
PL340284A1 (en)	2001-01-29
DE69839313D1 (de)	2008-05-08
EA200000449A1 (ru)	2000-12-25
NO20002025L (no)	2000-06-19
ATE390486T1 (de)	2008-04-15
AU749279B2 (en)	2002-06-20
PL194194B1 (pl)	2007-05-31
EP1676919A1 (en)	2006-07-05
CN1246462C (zh)	2006-03-22
PT1090128E (pt)	2008-04-17
AU749279C (en)	2004-09-16
CN1283231A (zh)	2001-02-07
CA2307175A1 (en)	1999-04-29
HUP0102257A3 (en)	2003-09-29
AR020048A1 (es)	2002-04-10
AP2000001811A0 (en)	2000-06-30
WO1999020767A1 (en)	1999-04-29
EP1676919B1 (en)	2014-07-23
ES2303362T3 (es)	2008-08-01
KR20010031370A (ko)	2001-04-16
DE69839313T2 (de)	2009-04-16
NO20002025D0 (no)	2000-04-18
EP1090128B1 (en)	2008-03-26
AR035786A2 (es)	2004-07-14
HRP20000234A2 (en)	2001-08-31
EP1090128A1 (en)	2001-04-11
HU225993B1 (en)	2008-02-28
US6017882A (en)	2000-01-25
IL135603A0 (en)	2001-05-20
MY136336A (en)	2008-09-30
ID26330A (id)	2000-12-14
NZ504114A (en)	2002-10-25
SG105547A1 (en)	2004-08-27
CA2307175C (en)	2009-04-14
DK1090128T3 (da)	2008-06-23
TR200001105T2 (tr)	2000-09-21
ES2496104T3 (es)	2014-09-18
BR9814611A (pt)	2000-10-03

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DE69834353D1 (de)	2006-06-01	Leistungsteilungs-/-addierschaltung
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ID24430A (id)	2000-07-20	Turunan-turunan benzamidina
NO2011017I2 (no)	2013-04-02	Retigabin
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DE59806582D1 (de)	2003-01-23	Sitzmöbel
NO20001415D0 (no)	2000-03-17	Farmasøytikum inneholdende vitamin-K-avhengige faktorer
DE69829900D1 (de)	2005-06-02	Neigungsverstellvorrichtung
DE59805888D1 (de)	2002-11-14	Schleifkörper
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ID21138A (id)	1999-04-29	Teknologi film-tipis untuk head-drum
KR980000493U (ko)	1998-03-30	의자
ATA188297A (de)	2001-05-15	Beschlag
UA1635S (uk)	1997-10-31	Картка - медичний маячок
FIU970370U0 (fi)	1997-08-26	Liitäntäkeskus
FI970511A0 (fi)	1997-02-07	Lutbart plan
FI2868U1 (fi)	1997-04-29	Syöttötuoli
FR2778665B1 (fr)	2000-06-30	Polypeptide prax-1
FI974635A0 (fi)	1997-12-29	I vaermebatteri integrerbar ventilkonstruktion
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